Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$MAX_01 |
Enrichment Score (ES) | 0.5084004 |
Normalized Enrichment Score (NES) | 1.2492489 |
Nominal p-value | 0.070512824 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 6 | 5.043 | 0.0625 | Yes | ||
2 | TIMM10 | 610070 1450019 | 20 | 4.600 | 0.1191 | Yes | ||
3 | HNRPA1 | 4670398 5050687 | 57 | 3.108 | 0.1558 | Yes | ||
4 | TFRC | 4050551 | 123 | 2.289 | 0.1808 | Yes | ||
5 | BAX | 3830008 | 144 | 2.108 | 0.2060 | Yes | ||
6 | ATF4 | 730441 1740195 | 203 | 1.842 | 0.2258 | Yes | ||
7 | SUPT16H | 1240333 | 229 | 1.755 | 0.2463 | Yes | ||
8 | CFL1 | 2340735 | 251 | 1.707 | 0.2664 | Yes | ||
9 | CAD | 2340717 | 273 | 1.626 | 0.2856 | Yes | ||
10 | PLCG2 | 5720008 | 292 | 1.552 | 0.3039 | Yes | ||
11 | AKAP12 | 1450739 | 321 | 1.471 | 0.3207 | Yes | ||
12 | QTRT1 | 1340162 | 354 | 1.389 | 0.3363 | Yes | ||
13 | CCAR1 | 3190092 | 388 | 1.319 | 0.3509 | Yes | ||
14 | NOTCH1 | 3390114 | 463 | 1.166 | 0.3614 | Yes | ||
15 | PTGES2 | 4210097 | 475 | 1.156 | 0.3753 | Yes | ||
16 | AATF | 5220575 | 587 | 1.023 | 0.3820 | Yes | ||
17 | VPS16 | 430064 3390041 6860301 | 630 | 0.976 | 0.3919 | Yes | ||
18 | PFDN2 | 4230156 | 738 | 0.895 | 0.3972 | Yes | ||
19 | PA2G4 | 2030463 | 742 | 0.894 | 0.4082 | Yes | ||
20 | HMGA1 | 6580408 | 824 | 0.834 | 0.4142 | Yes | ||
21 | UBE4B | 780008 3610154 | 852 | 0.812 | 0.4228 | Yes | ||
22 | GTF2H1 | 2570746 2650148 | 855 | 0.811 | 0.4328 | Yes | ||
23 | DDX3X | 2190020 | 877 | 0.789 | 0.4415 | Yes | ||
24 | ACY1 | 2360279 6550161 | 970 | 0.708 | 0.4454 | Yes | ||
25 | NUDC | 4780025 | 986 | 0.691 | 0.4532 | Yes | ||
26 | ASNA1 | 3830041 | 1037 | 0.664 | 0.4587 | Yes | ||
27 | TIMM8A | 110279 | 1057 | 0.652 | 0.4658 | Yes | ||
28 | OPRS1 | 6130128 6290717 | 1100 | 0.628 | 0.4713 | Yes | ||
29 | PPRC1 | 1740441 | 1121 | 0.612 | 0.4779 | Yes | ||
30 | FKBP11 | 3170575 | 1126 | 0.610 | 0.4853 | Yes | ||
31 | MRPL27 | 2060131 | 1233 | 0.564 | 0.4866 | Yes | ||
32 | EIF4B | 5390563 5270577 | 1274 | 0.548 | 0.4912 | Yes | ||
33 | PSME3 | 2810537 | 1319 | 0.530 | 0.4954 | Yes | ||
34 | PRPS1 | 6350129 | 1321 | 0.529 | 0.5020 | Yes | ||
35 | EIF2C2 | 770451 | 1325 | 0.528 | 0.5084 | Yes | ||
36 | CLN3 | 780368 | 1619 | 0.419 | 0.4977 | No | ||
37 | EEF1B2 | 4850400 6130161 | 1666 | 0.402 | 0.5002 | No | ||
38 | SRP72 | 3990427 | 1789 | 0.367 | 0.4982 | No | ||
39 | ZCCHC7 | 6510592 | 1934 | 0.326 | 0.4945 | No | ||
40 | CD164 | 3830594 | 1967 | 0.318 | 0.4967 | No | ||
41 | ATP6V1A | 6590242 | 2298 | 0.237 | 0.4817 | No | ||
42 | TCF4 | 520021 | 2331 | 0.231 | 0.4829 | No | ||
43 | TAF6L | 1850056 | 2450 | 0.206 | 0.4791 | No | ||
44 | HIRA | 4480609 5270167 | 2749 | 0.159 | 0.4649 | No | ||
45 | ATP6V1C1 | 2690324 5220528 | 2836 | 0.147 | 0.4620 | No | ||
46 | STMN1 | 1990717 | 2854 | 0.145 | 0.4629 | No | ||
47 | RPS2 | 1340647 | 2866 | 0.144 | 0.4641 | No | ||
48 | COPZ1 | 6940100 | 3087 | 0.122 | 0.4537 | No | ||
49 | TOPORS | 4060592 | 3089 | 0.122 | 0.4552 | No | ||
50 | TCOF1 | 2680086 | 3171 | 0.114 | 0.4522 | No | ||
51 | SNTB2 | 2630014 5390035 | 3203 | 0.111 | 0.4519 | No | ||
52 | COMMD3 | 2510259 | 3210 | 0.111 | 0.4530 | No | ||
53 | DHX35 | 1230440 | 3317 | 0.100 | 0.4485 | No | ||
54 | EN1 | 5360168 7050025 | 3548 | 0.082 | 0.4370 | No | ||
55 | QTRTD1 | 7000053 | 3662 | 0.073 | 0.4318 | No | ||
56 | RUNX2 | 1400193 4230215 | 3699 | 0.070 | 0.4308 | No | ||
57 | AMPD2 | 630093 1170070 | 3769 | 0.066 | 0.4278 | No | ||
58 | SLC26A2 | 2360278 | 4005 | 0.054 | 0.4158 | No | ||
59 | SYT3 | 6380017 | 4014 | 0.053 | 0.4160 | No | ||
60 | CHD4 | 5420059 6130338 6380717 | 4203 | 0.046 | 0.4064 | No | ||
61 | UBXD3 | 5050193 | 4291 | 0.043 | 0.4022 | No | ||
62 | SUCLG2 | 5340397 5700270 | 4316 | 0.042 | 0.4014 | No | ||
63 | PPP1R3C | 2640170 | 4361 | 0.041 | 0.3996 | No | ||
64 | RCL1 | 1980408 2680008 3800176 | 4561 | 0.036 | 0.3892 | No | ||
65 | RAB3IL1 | 380685 5420176 | 4576 | 0.036 | 0.3889 | No | ||
66 | ARMET | 5130670 | 4591 | 0.036 | 0.3886 | No | ||
67 | ZNF318 | 5890091 6130021 | 4885 | 0.030 | 0.3731 | No | ||
68 | RAI14 | 770288 1660075 | 5056 | 0.027 | 0.3642 | No | ||
69 | NEUROD1 | 3060619 | 5313 | 0.023 | 0.3506 | No | ||
70 | TESK2 | 6520524 | 5352 | 0.023 | 0.3488 | No | ||
71 | DSCAM | 1780050 2450731 2810438 | 5499 | 0.021 | 0.3412 | No | ||
72 | GATA5 | 430465 | 5762 | 0.018 | 0.3272 | No | ||
73 | PICALM | 1940280 | 6478 | 0.013 | 0.2886 | No | ||
74 | IRS4 | 430341 1190450 | 6568 | 0.012 | 0.2839 | No | ||
75 | SLC1A7 | 1990181 | 6713 | 0.011 | 0.2763 | No | ||
76 | GUCY1A2 | 1660441 | 6895 | 0.010 | 0.2666 | No | ||
77 | EIF3S10 | 1190079 3840176 | 6992 | 0.010 | 0.2615 | No | ||
78 | FGF14 | 2630390 3520075 6770048 | 7022 | 0.010 | 0.2601 | No | ||
79 | DUSP7 | 2940309 | 7071 | 0.009 | 0.2576 | No | ||
80 | USP15 | 610592 3520504 | 7267 | 0.009 | 0.2471 | No | ||
81 | ETV1 | 70735 2940603 5080463 | 7354 | 0.008 | 0.2425 | No | ||
82 | LIN28 | 6590672 | 7554 | 0.007 | 0.2318 | No | ||
83 | DNMT3A | 4050068 4810717 | 7784 | 0.006 | 0.2195 | No | ||
84 | POGK | 5290315 | 7932 | 0.006 | 0.2116 | No | ||
85 | SLC38A5 | 540093 | 8155 | 0.005 | 0.1996 | No | ||
86 | XPO1 | 540707 | 8292 | 0.005 | 0.1923 | No | ||
87 | HOXD10 | 6100039 | 8634 | 0.003 | 0.1739 | No | ||
88 | ZBTB10 | 4200132 | 8667 | 0.003 | 0.1722 | No | ||
89 | HOXC5 | 1580017 | 8919 | 0.002 | 0.1586 | No | ||
90 | PCDHA10 | 3830725 | 8977 | 0.002 | 0.1556 | No | ||
91 | ODC1 | 5670168 | 9074 | 0.002 | 0.1504 | No | ||
92 | SSR1 | 5890100 | 9108 | 0.002 | 0.1486 | No | ||
93 | AKAP1 | 110148 1740735 2260019 7000563 | 9168 | 0.002 | 0.1454 | No | ||
94 | AP1S2 | 780279 4280707 | 9355 | 0.001 | 0.1354 | No | ||
95 | MEOX2 | 6400288 | 9397 | 0.001 | 0.1332 | No | ||
96 | SNX5 | 1570021 6860609 | 9427 | 0.001 | 0.1316 | No | ||
97 | BMP6 | 2100128 | 9745 | -0.000 | 0.1144 | No | ||
98 | LZTFL1 | 540114 | 9975 | -0.001 | 0.1020 | No | ||
99 | SIRT1 | 1190731 | 10151 | -0.001 | 0.0925 | No | ||
100 | NFX1 | 450504 | 10516 | -0.002 | 0.0728 | No | ||
101 | MTHFD1 | 5900398 6520427 | 10571 | -0.003 | 0.0699 | No | ||
102 | OPRD1 | 4280138 | 11062 | -0.004 | 0.0434 | No | ||
103 | MAX | 5220021 | 11143 | -0.005 | 0.0392 | No | ||
104 | HOXA11 | 6980133 | 11187 | -0.005 | 0.0369 | No | ||
105 | NRIP3 | 1340372 | 11329 | -0.005 | 0.0293 | No | ||
106 | FOXD3 | 6550156 | 11353 | -0.005 | 0.0281 | No | ||
107 | CPT1A | 6350093 | 11395 | -0.005 | 0.0260 | No | ||
108 | BCOR | 1660452 3940053 | 11421 | -0.006 | 0.0247 | No | ||
109 | SEPT3 | 3830022 5290079 | 11806 | -0.007 | 0.0040 | No | ||
110 | NPM1 | 4730427 | 11860 | -0.007 | 0.0012 | No | ||
111 | SYNCRIP | 1690195 3140113 4670279 | 12143 | -0.009 | -0.0140 | No | ||
112 | ATOH8 | 4540204 | 12374 | -0.010 | -0.0264 | No | ||
113 | HOXB5 | 2900538 | 12487 | -0.010 | -0.0323 | No | ||
114 | NDUFS1 | 2650253 | 12667 | -0.011 | -0.0419 | No | ||
115 | ELAVL3 | 2850014 | 12764 | -0.012 | -0.0469 | No | ||
116 | IPO13 | 3870088 | 13106 | -0.014 | -0.0652 | No | ||
117 | UBE2B | 4780497 | 13313 | -0.016 | -0.0762 | No | ||
118 | NPTX1 | 3710736 | 13341 | -0.017 | -0.0774 | No | ||
119 | ADAMTS17 | 6510739 | 13463 | -0.018 | -0.0838 | No | ||
120 | CBX5 | 3830072 6290167 | 13487 | -0.018 | -0.0848 | No | ||
121 | SNCAIP | 4010551 | 13516 | -0.018 | -0.0861 | No | ||
122 | TCERG1 | 2350551 4540397 5220746 | 13543 | -0.018 | -0.0873 | No | ||
123 | SUMF1 | 730050 | 13627 | -0.020 | -0.0915 | No | ||
124 | ANAPC13 | 3800446 | 13837 | -0.023 | -0.1026 | No | ||
125 | TGFB2 | 4920292 | 14037 | -0.026 | -0.1130 | No | ||
126 | GGN | 1410528 4210082 5290170 | 14339 | -0.032 | -0.1290 | No | ||
127 | HOXB7 | 4540706 4610358 | 14570 | -0.037 | -0.1410 | No | ||
128 | SLC38A2 | 1470242 3800026 | 14697 | -0.041 | -0.1473 | No | ||
129 | PER1 | 3290315 | 14719 | -0.042 | -0.1479 | No | ||
130 | KCNE4 | 2470102 | 14954 | -0.053 | -0.1599 | No | ||
131 | DVL2 | 6110162 | 15006 | -0.055 | -0.1620 | No | ||
132 | SLC31A2 | 1450577 | 15445 | -0.085 | -0.1847 | No | ||
133 | MRPL40 | 2370215 | 15446 | -0.085 | -0.1836 | No | ||
134 | PTMA | 5570148 | 15567 | -0.096 | -0.1889 | No | ||
135 | GNB2 | 2350053 | 15749 | -0.115 | -0.1973 | No | ||
136 | BOK | 1170373 5860446 | 15952 | -0.141 | -0.2065 | No | ||
137 | EIF4E | 1580403 70133 6380215 | 16200 | -0.177 | -0.2177 | No | ||
138 | FEN1 | 1770541 | 16217 | -0.179 | -0.2163 | No | ||
139 | CSK | 6350593 | 16371 | -0.204 | -0.2221 | No | ||
140 | MAT2A | 4070026 4730079 6020280 | 16421 | -0.215 | -0.2220 | No | ||
141 | TOP1 | 770471 4060632 6650324 | 16424 | -0.215 | -0.2195 | No | ||
142 | HHEX | 2340575 | 16533 | -0.235 | -0.2224 | No | ||
143 | GPX1 | 4150093 | 16538 | -0.236 | -0.2197 | No | ||
144 | PDK2 | 2690017 | 16570 | -0.243 | -0.2183 | No | ||
145 | MXD4 | 4810113 | 16630 | -0.252 | -0.2184 | No | ||
146 | CENTB5 | 5690128 | 16650 | -0.255 | -0.2162 | No | ||
147 | ILF3 | 940722 3190647 6520110 | 16695 | -0.265 | -0.2153 | No | ||
148 | SMAD2 | 4200592 | 16785 | -0.281 | -0.2166 | No | ||
149 | ALDH6A1 | 1770746 | 16886 | -0.310 | -0.2182 | No | ||
150 | LAMP1 | 2470524 | 17131 | -0.385 | -0.2266 | No | ||
151 | PPM1A | 1170301 5900273 | 17166 | -0.397 | -0.2235 | No | ||
152 | BCAS3 | 4050647 | 17388 | -0.496 | -0.2293 | No | ||
153 | PRKCH | 5720079 | 17442 | -0.520 | -0.2257 | No | ||
154 | LZTS2 | 2260440 | 17450 | -0.524 | -0.2196 | No | ||
155 | BRDT | 3940102 | 17484 | -0.536 | -0.2147 | No | ||
156 | DNAJB5 | 2900215 | 17717 | -0.653 | -0.2191 | No | ||
157 | HOXA7 | 5910152 | 17729 | -0.661 | -0.2115 | No | ||
158 | GJA1 | 5220731 | 17809 | -0.725 | -0.2068 | No | ||
159 | ZFYVE26 | 6860152 | 18008 | -0.888 | -0.2064 | No | ||
160 | MTCH2 | 3780603 6620215 | 18085 | -0.988 | -0.1982 | No | ||
161 | KBTBD2 | 2320014 | 18294 | -1.366 | -0.1925 | No | ||
162 | EPC1 | 1570050 5290095 6900193 | 18382 | -1.642 | -0.1768 | No | ||
163 | HBP1 | 2510102 3130010 4210619 | 18428 | -1.800 | -0.1568 | No | ||
164 | DUSP1 | 6860121 | 18444 | -1.881 | -0.1342 | No | ||
165 | ISGF3G | 3190131 7100142 | 18453 | -1.937 | -0.1105 | No | ||
166 | CDK5R1 | 3870161 | 18465 | -2.008 | -0.0860 | No | ||
167 | GNAS | 630441 1850373 4050152 | 18468 | -2.029 | -0.0609 | No | ||
168 | ATF7IP | 2690176 6770021 | 18478 | -2.122 | -0.0349 | No | ||
169 | NIT1 | 1230338 3940671 | 18589 | -3.401 | 0.0015 | No |