Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$LEF1_Q2 |
Enrichment Score (ES) | 0.5944158 |
Normalized Enrichment Score (NES) | 1.4275038 |
Nominal p-value | 0.008361204 |
FDR q-value | 1.0 |
FWER p-Value | 0.998 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARID1A | 2630022 1690551 4810110 | 3 | 6.330 | 0.1338 | Yes | ||
2 | SDHC | 3140347 6100156 | 4 | 5.878 | 0.2581 | Yes | ||
3 | TIMM10 | 610070 1450019 | 20 | 4.600 | 0.3546 | Yes | ||
4 | SLC6A9 | 2470520 | 204 | 1.842 | 0.3837 | Yes | ||
5 | CD160 | 4210377 | 371 | 1.347 | 0.4032 | Yes | ||
6 | SMYD2 | 5050026 | 413 | 1.270 | 0.4278 | Yes | ||
7 | SYTL1 | 510487 | 427 | 1.224 | 0.4530 | Yes | ||
8 | WNT8B | 4560301 | 438 | 1.211 | 0.4781 | Yes | ||
9 | NDUFS3 | 1690136 5340528 | 777 | 0.874 | 0.4783 | Yes | ||
10 | BMI1 | 3830026 2630204 | 842 | 0.820 | 0.4922 | Yes | ||
11 | UBE4B | 780008 3610154 | 852 | 0.812 | 0.5089 | Yes | ||
12 | PRKRIR | 2370402 | 910 | 0.758 | 0.5218 | Yes | ||
13 | GLUD1 | 4210372 | 938 | 0.730 | 0.5358 | Yes | ||
14 | DHCR24 | 840600 1050672 6290097 | 1007 | 0.680 | 0.5465 | Yes | ||
15 | CNR2 | 2760398 | 1025 | 0.669 | 0.5598 | Yes | ||
16 | ELOVL1 | 2450019 4760138 5340685 | 1153 | 0.598 | 0.5656 | Yes | ||
17 | DYRK3 | 1090014 | 1263 | 0.555 | 0.5714 | Yes | ||
18 | RRM1 | 4150433 | 1302 | 0.536 | 0.5807 | Yes | ||
19 | RPA2 | 2760301 5420195 | 1374 | 0.508 | 0.5876 | Yes | ||
20 | SYT13 | 5910110 | 1438 | 0.484 | 0.5944 | Yes | ||
21 | AHCYL1 | 540609 | 1939 | 0.325 | 0.5742 | No | ||
22 | SEMA4G | 5890026 | 1955 | 0.321 | 0.5802 | No | ||
23 | EIF4G2 | 3800575 6860184 | 2335 | 0.229 | 0.5645 | No | ||
24 | YARS | 70739 | 2440 | 0.209 | 0.5633 | No | ||
25 | BSCL2 | 2680671 | 2495 | 0.199 | 0.5646 | No | ||
26 | EFNA4 | 4280309 6550576 | 2545 | 0.189 | 0.5660 | No | ||
27 | NDUFC2 | 580075 | 2909 | 0.138 | 0.5492 | No | ||
28 | NCDN | 50040 1980739 3520603 | 3043 | 0.126 | 0.5447 | No | ||
29 | RUNX3 | 3800546 | 3117 | 0.119 | 0.5433 | No | ||
30 | TRIM33 | 580619 2230280 3990433 6200747 | 3420 | 0.091 | 0.5288 | No | ||
31 | RNF11 | 3990068 5080458 | 3436 | 0.090 | 0.5299 | No | ||
32 | PDC | 3140400 3780184 | 3559 | 0.081 | 0.5250 | No | ||
33 | SLC25A28 | 6590600 | 3580 | 0.079 | 0.5256 | No | ||
34 | AMPD3 | 610369 3360528 | 3755 | 0.067 | 0.5176 | No | ||
35 | MOV10 | 50673 430577 3870280 | 3774 | 0.066 | 0.5180 | No | ||
36 | TMEM9 | 130039 | 3845 | 0.062 | 0.5155 | No | ||
37 | BAI2 | 380632 630113 6650170 | 3902 | 0.059 | 0.5138 | No | ||
38 | DUSP10 | 2850673 3360064 | 4142 | 0.048 | 0.5019 | No | ||
39 | MMP21 | 4480673 | 4184 | 0.047 | 0.5006 | No | ||
40 | TIAL1 | 4150048 6510605 | 4191 | 0.046 | 0.5013 | No | ||
41 | HABP2 | 5360541 6350273 | 4307 | 0.043 | 0.4960 | No | ||
42 | SOX6 | 2940458 4070601 6840717 | 4414 | 0.040 | 0.4911 | No | ||
43 | DDR2 | 7050273 | 4518 | 0.037 | 0.4863 | No | ||
44 | HNRPR | 2320440 2900601 4610008 | 4750 | 0.032 | 0.4744 | No | ||
45 | SCUBE2 | 2850315 5130040 | 4825 | 0.031 | 0.4711 | No | ||
46 | GRK5 | 1940348 4670053 | 4939 | 0.029 | 0.4656 | No | ||
47 | COL13A1 | 4120079 | 4976 | 0.028 | 0.4642 | No | ||
48 | ELF5 | 3140156 5220020 | 5112 | 0.026 | 0.4575 | No | ||
49 | RERE | 3940279 | 5188 | 0.025 | 0.4539 | No | ||
50 | VAX1 | 6660750 | 5235 | 0.024 | 0.4519 | No | ||
51 | CLCNKA | 1740050 | 5519 | 0.021 | 0.4371 | No | ||
52 | PTCH2 | 2900092 | 5694 | 0.019 | 0.4280 | No | ||
53 | RGL1 | 1500097 6900450 | 5824 | 0.018 | 0.4214 | No | ||
54 | CACNB2 | 1500095 7330707 | 5868 | 0.017 | 0.4195 | No | ||
55 | MRVI1 | 4810338 4850601 5900441 | 6362 | 0.014 | 0.3931 | No | ||
56 | MPZ | 1990333 | 6432 | 0.013 | 0.3896 | No | ||
57 | PRRX1 | 4120193 4480390 | 6452 | 0.013 | 0.3888 | No | ||
58 | DKK1 | 1940215 | 6485 | 0.013 | 0.3874 | No | ||
59 | MFN2 | 2260195 6100164 | 6501 | 0.012 | 0.3868 | No | ||
60 | ANK3 | 1500161 2900435 4210154 6400100 | 6673 | 0.012 | 0.3778 | No | ||
61 | LMO1 | 3170528 | 6765 | 0.011 | 0.3731 | No | ||
62 | HIAT1 | 1580176 | 6838 | 0.011 | 0.3694 | No | ||
63 | PTPRJ | 4010707 | 6845 | 0.010 | 0.3693 | No | ||
64 | NEUROG3 | 6980451 | 6935 | 0.010 | 0.3647 | No | ||
65 | SORCS1 | 60411 5890373 | 6942 | 0.010 | 0.3646 | No | ||
66 | NHLH2 | 6200021 | 6946 | 0.010 | 0.3647 | No | ||
67 | PLA2G4A | 6380364 | 7420 | 0.008 | 0.3392 | No | ||
68 | ESRRG | 4010181 | 7440 | 0.008 | 0.3384 | No | ||
69 | PHTF1 | 7050441 | 7530 | 0.007 | 0.3337 | No | ||
70 | LIN28 | 6590672 | 7554 | 0.007 | 0.3326 | No | ||
71 | IL20 | 4850647 | 7930 | 0.006 | 0.3125 | No | ||
72 | SH2D4B | 670204 | 8165 | 0.005 | 0.2999 | No | ||
73 | PVRL4 | 2340048 6220195 | 8338 | 0.004 | 0.2907 | No | ||
74 | TCERG1L | 3360707 | 8365 | 0.004 | 0.2894 | No | ||
75 | RCN1 | 2480041 | 8405 | 0.004 | 0.2873 | No | ||
76 | DPYD | 6110095 | 8479 | 0.004 | 0.2835 | No | ||
77 | SLC17A6 | 4210576 | 8483 | 0.004 | 0.2834 | No | ||
78 | TLL2 | 6220040 | 8524 | 0.004 | 0.2813 | No | ||
79 | CGN | 5890139 6370167 6400537 | 8556 | 0.004 | 0.2797 | No | ||
80 | IL19 | 6040142 | 8766 | 0.003 | 0.2684 | No | ||
81 | CUBN | 630338 | 8779 | 0.003 | 0.2679 | No | ||
82 | AP4B1 | 2900300 | 8845 | 0.003 | 0.2644 | No | ||
83 | SPOCK2 | 6650369 | 9522 | 0.001 | 0.2278 | No | ||
84 | GAB2 | 1410280 2340520 4280040 | 9538 | 0.000 | 0.2270 | No | ||
85 | LRP8 | 3610746 5360035 | 9894 | -0.001 | 0.2078 | No | ||
86 | GNG3 | 6980397 | 10097 | -0.001 | 0.1969 | No | ||
87 | NEXN | 1240017 5290047 | 10118 | -0.001 | 0.1958 | No | ||
88 | SLC22A8 | 3520204 | 10157 | -0.001 | 0.1938 | No | ||
89 | SERPINC1 | 1780717 | 10444 | -0.002 | 0.1784 | No | ||
90 | UBE2D1 | 1850400 | 10639 | -0.003 | 0.1679 | No | ||
91 | LRRTM3 | 4210021 | 11334 | -0.005 | 0.1305 | No | ||
92 | COL11A1 | 2100300 2810136 4200706 4810524 | 11436 | -0.006 | 0.1251 | No | ||
93 | PAX6 | 1190025 | 11545 | -0.006 | 0.1194 | No | ||
94 | LPHN2 | 4480010 | 11649 | -0.006 | 0.1140 | No | ||
95 | PROX1 | 4210193 | 11969 | -0.008 | 0.0968 | No | ||
96 | SFXN2 | 2650563 3140095 3830762 3870398 | 12362 | -0.010 | 0.0758 | No | ||
97 | NEK7 | 4540026 | 12718 | -0.012 | 0.0569 | No | ||
98 | BSND | 1780041 | 12737 | -0.012 | 0.0561 | No | ||
99 | SV2A | 1450039 5570685 | 12866 | -0.013 | 0.0495 | No | ||
100 | ASB13 | 1090070 | 12897 | -0.013 | 0.0481 | No | ||
101 | ZFYVE9 | 6980288 7100017 | 13163 | -0.015 | 0.0341 | No | ||
102 | PAK1 | 4540315 | 13205 | -0.015 | 0.0322 | No | ||
103 | RET | 3850746 | 13211 | -0.015 | 0.0322 | No | ||
104 | WNT9A | 3830711 | 13234 | -0.015 | 0.0314 | No | ||
105 | EPHA2 | 5890056 | 13415 | -0.017 | 0.0220 | No | ||
106 | KBTBD4 | 70465 3840093 | 13485 | -0.018 | 0.0186 | No | ||
107 | LHX4 | 6940551 | 13625 | -0.020 | 0.0115 | No | ||
108 | LEMD1 | 3990132 5720187 | 13747 | -0.021 | 0.0054 | No | ||
109 | NPPA | 6550328 | 13790 | -0.022 | 0.0036 | No | ||
110 | OVOL1 | 1690131 | 13918 | -0.024 | -0.0027 | No | ||
111 | DGAT2 | 5130685 | 13930 | -0.024 | -0.0028 | No | ||
112 | SLC26A9 | 3440722 5340088 7510093 | 14227 | -0.029 | -0.0182 | No | ||
113 | NAV1 | 4210519 6620129 | 14317 | -0.032 | -0.0224 | No | ||
114 | CYP2E1 | 4480209 | 14353 | -0.032 | -0.0236 | No | ||
115 | ARNT | 1170672 5670711 | 14409 | -0.033 | -0.0259 | No | ||
116 | ADAM12 | 3390132 4070347 | 15187 | -0.066 | -0.0666 | No | ||
117 | UAP1 | 3060093 | 15443 | -0.085 | -0.0786 | No | ||
118 | SLC16A9 | 6220497 | 15505 | -0.091 | -0.0799 | No | ||
119 | GFRA1 | 3610152 | 15534 | -0.093 | -0.0795 | No | ||
120 | ENTPD7 | 1980601 | 15595 | -0.099 | -0.0806 | No | ||
121 | CNTF | 450128 870253 1780068 6520195 | 15639 | -0.104 | -0.0808 | No | ||
122 | ELAVL4 | 50735 3360086 5220167 | 15832 | -0.126 | -0.0885 | No | ||
123 | S100A3 | 6400563 | 15916 | -0.136 | -0.0901 | No | ||
124 | TCF7L2 | 2190348 5220113 | 15948 | -0.141 | -0.0888 | No | ||
125 | ACTR1A | 5860070 | 15965 | -0.143 | -0.0867 | No | ||
126 | FRAG1 | 1050504 1170152 2030092 | 16093 | -0.161 | -0.0901 | No | ||
127 | PANK1 | 670091 6220605 | 16261 | -0.186 | -0.0953 | No | ||
128 | CREM | 840156 6380438 6660041 6660168 | 16364 | -0.204 | -0.0965 | No | ||
129 | TACSTD2 | 6660341 | 16465 | -0.223 | -0.0972 | No | ||
130 | SIPA1 | 5220687 | 16478 | -0.225 | -0.0931 | No | ||
131 | ADD3 | 4150739 5390600 | 16573 | -0.243 | -0.0930 | No | ||
132 | CEPT1 | 1940047 | 16642 | -0.255 | -0.0913 | No | ||
133 | DCLRE1B | 540070 4730373 5550176 | 16672 | -0.260 | -0.0874 | No | ||
134 | ADRBK1 | 1340333 | 16790 | -0.283 | -0.0877 | No | ||
135 | ARL3 | 5690725 | 16973 | -0.331 | -0.0906 | No | ||
136 | TSG101 | 770148 | 17252 | -0.435 | -0.0964 | No | ||
137 | PTPN7 | 3450110 | 17336 | -0.473 | -0.0909 | No | ||
138 | PRDM2 | 780278 1940692 | 17488 | -0.538 | -0.0877 | No | ||
139 | SCAMP3 | 2360707 | 17732 | -0.662 | -0.0869 | No | ||
140 | EIF4EBP2 | 5670279 | 17798 | -0.716 | -0.0752 | No | ||
141 | SLC43A3 | 430168 5220400 | 17910 | -0.794 | -0.0645 | No | ||
142 | UCP2 | 2190050 4070711 | 18091 | -0.994 | -0.0532 | No | ||
143 | GADD45A | 2900717 | 18099 | -1.001 | -0.0324 | No | ||
144 | HSD11B1 | 450066 5550408 | 18314 | -1.402 | -0.0143 | No | ||
145 | CAP1 | 2650278 | 18327 | -1.446 | 0.0156 | No |