Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$GFI1_01 |
Enrichment Score (ES) | -0.61404014 |
Normalized Enrichment Score (NES) | -1.5796858 |
Nominal p-value | 0.0 |
FDR q-value | 0.1394209 |
FWER p-Value | 0.397 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ATP5G2 | 840068 | 684 | 0.934 | -0.0194 | No | ||
2 | ABCF2 | 630040 3140035 6450601 | 714 | 0.919 | -0.0035 | No | ||
3 | SREBF2 | 3390692 | 723 | 0.908 | 0.0133 | No | ||
4 | CSAD | 770215 | 728 | 0.903 | 0.0303 | No | ||
5 | MBNL1 | 2640762 7100048 | 822 | 0.837 | 0.0411 | No | ||
6 | HMGA1 | 6580408 | 824 | 0.834 | 0.0569 | No | ||
7 | MCTS1 | 6130133 | 995 | 0.688 | 0.0608 | No | ||
8 | EXOC7 | 3060037 | 1184 | 0.587 | 0.0617 | No | ||
9 | USP5 | 4850017 | 1252 | 0.557 | 0.0687 | No | ||
10 | MYO1C | 3190398 | 1679 | 0.396 | 0.0531 | No | ||
11 | TMPRSS2 | 2970279 | 1694 | 0.392 | 0.0598 | No | ||
12 | SFRS2 | 50707 380593 | 1912 | 0.330 | 0.0542 | No | ||
13 | BCL9L | 6940053 | 2123 | 0.279 | 0.0481 | No | ||
14 | TRAF4 | 3060041 4920528 6980286 | 2176 | 0.267 | 0.0504 | No | ||
15 | TCF4 | 520021 | 2331 | 0.231 | 0.0464 | No | ||
16 | PPP2R2A | 2900014 5700575 | 2484 | 0.200 | 0.0420 | No | ||
17 | XPO5 | 2850286 | 2744 | 0.159 | 0.0309 | No | ||
18 | STMN1 | 1990717 | 2854 | 0.145 | 0.0278 | No | ||
19 | GPR17 | 5890671 | 2917 | 0.137 | 0.0270 | No | ||
20 | PPARGC1B | 3290114 | 2930 | 0.136 | 0.0290 | No | ||
21 | MYH10 | 2640673 | 2949 | 0.134 | 0.0305 | No | ||
22 | TRIM23 | 580168 6510672 | 2984 | 0.132 | 0.0312 | No | ||
23 | PRKAG1 | 6450091 | 3107 | 0.120 | 0.0268 | No | ||
24 | PRIMA1 | 1500673 6760671 | 3533 | 0.082 | 0.0053 | No | ||
25 | PDC | 3140400 3780184 | 3559 | 0.081 | 0.0055 | No | ||
26 | TLK1 | 7100605 | 3570 | 0.080 | 0.0065 | No | ||
27 | MTMR4 | 4540524 | 3746 | 0.067 | -0.0017 | No | ||
28 | ETS1 | 5270278 6450717 6620465 | 3819 | 0.063 | -0.0044 | No | ||
29 | WDR23 | 2030372 | 3881 | 0.060 | -0.0066 | No | ||
30 | GPRC5D | 4760021 | 3906 | 0.059 | -0.0068 | No | ||
31 | PDE4D | 2470528 6660014 | 3914 | 0.059 | -0.0060 | No | ||
32 | NR2F2 | 3170609 3310577 | 4149 | 0.048 | -0.0178 | No | ||
33 | DNAJB4 | 380195 2760372 3940735 | 4224 | 0.045 | -0.0210 | No | ||
34 | CNTN6 | 2630711 | 4370 | 0.041 | -0.0281 | No | ||
35 | RPS6KB1 | 1450427 5080110 6200563 | 4372 | 0.041 | -0.0274 | No | ||
36 | DPF3 | 2650128 2970168 | 4445 | 0.039 | -0.0305 | No | ||
37 | CNKSR1 | 730528 3390672 | 4449 | 0.039 | -0.0299 | No | ||
38 | HOXC8 | 6220050 | 4452 | 0.039 | -0.0293 | No | ||
39 | FOXP2 | 3520561 4150372 4760524 | 4495 | 0.038 | -0.0309 | No | ||
40 | DDR2 | 7050273 | 4518 | 0.037 | -0.0314 | No | ||
41 | HOXA9 | 610494 4730040 5130601 | 4660 | 0.034 | -0.0384 | No | ||
42 | GAS2 | 1340082 | 4711 | 0.033 | -0.0405 | No | ||
43 | AVP | 2100113 | 4766 | 0.032 | -0.0428 | No | ||
44 | ICAM5 | 2350647 | 4809 | 0.031 | -0.0445 | No | ||
45 | DSG3 | 3940014 | 4970 | 0.028 | -0.0526 | No | ||
46 | CRYZL1 | 730022 2320044 | 4991 | 0.028 | -0.0532 | No | ||
47 | HIVEP3 | 3990551 | 5026 | 0.027 | -0.0545 | No | ||
48 | OTP | 2630070 | 5153 | 0.025 | -0.0609 | No | ||
49 | HOXA3 | 3610632 6020358 | 5425 | 0.022 | -0.0752 | No | ||
50 | HOXB6 | 4210739 | 5445 | 0.022 | -0.0758 | No | ||
51 | HOXB3 | 520292 | 5473 | 0.021 | -0.0769 | No | ||
52 | ZIC1 | 670113 | 5539 | 0.021 | -0.0800 | No | ||
53 | ASB4 | 2100064 3060059 | 5633 | 0.020 | -0.0847 | No | ||
54 | ANGPT1 | 3990368 5130288 6770035 | 5684 | 0.019 | -0.0870 | No | ||
55 | HOXC4 | 1940193 | 5751 | 0.018 | -0.0902 | No | ||
56 | MAP2K7 | 2260086 | 5805 | 0.018 | -0.0928 | No | ||
57 | CACNB2 | 1500095 7330707 | 5868 | 0.017 | -0.0958 | No | ||
58 | PPARGC1A | 4670040 | 5938 | 0.017 | -0.0992 | No | ||
59 | HIST1H1E | 6980706 | 6027 | 0.016 | -0.1037 | No | ||
60 | SOSTDC1 | 6760017 | 6029 | 0.016 | -0.1035 | No | ||
61 | SOX9 | 5720681 | 6113 | 0.015 | -0.1077 | No | ||
62 | NFIA | 2760129 5860278 | 6439 | 0.013 | -0.1251 | No | ||
63 | HOXB8 | 3710450 | 6441 | 0.013 | -0.1249 | No | ||
64 | HOXA10 | 6110397 7100458 | 6442 | 0.013 | -0.1246 | No | ||
65 | SP8 | 4060576 | 6627 | 0.012 | -0.1344 | No | ||
66 | PHF8 | 70722 | 6718 | 0.011 | -0.1391 | No | ||
67 | RKHD3 | 6180471 | 6720 | 0.011 | -0.1389 | No | ||
68 | PURA | 3870156 | 7035 | 0.010 | -0.1558 | No | ||
69 | HIST1H1T | 130632 | 7125 | 0.009 | -0.1604 | No | ||
70 | BMP4 | 380113 | 7150 | 0.009 | -0.1616 | No | ||
71 | CALN1 | 3610722 | 7423 | 0.008 | -0.1762 | No | ||
72 | JPH4 | 780020 | 7568 | 0.007 | -0.1839 | No | ||
73 | EBF2 | 940324 | 7877 | 0.006 | -0.2005 | No | ||
74 | MSR1 | 940538 | 7891 | 0.006 | -0.2010 | No | ||
75 | DSPP | 5890403 | 7934 | 0.006 | -0.2032 | No | ||
76 | CLMN | 1340446 1660433 2940670 | 7984 | 0.006 | -0.2058 | No | ||
77 | BDNF | 2940128 3520368 | 8004 | 0.006 | -0.2067 | No | ||
78 | HOXD11 | 2260242 | 8020 | 0.006 | -0.2074 | No | ||
79 | NGEF | 3190538 | 8032 | 0.006 | -0.2079 | No | ||
80 | GPR20 | 6620601 | 8109 | 0.005 | -0.2119 | No | ||
81 | PROCR | 4920687 | 8374 | 0.004 | -0.2262 | No | ||
82 | GRPR | 6020170 | 8433 | 0.004 | -0.2292 | No | ||
83 | SOX15 | 2470603 | 8506 | 0.004 | -0.2331 | No | ||
84 | PCDH8 | 2360047 4200452 | 8537 | 0.004 | -0.2346 | No | ||
85 | CGN | 5890139 6370167 6400537 | 8556 | 0.004 | -0.2355 | No | ||
86 | CAMK2D | 2370685 | 8562 | 0.004 | -0.2357 | No | ||
87 | HOXD10 | 6100039 | 8634 | 0.003 | -0.2395 | No | ||
88 | ITSN1 | 2640577 | 8639 | 0.003 | -0.2397 | No | ||
89 | SLC26A3 | 380750 | 8851 | 0.003 | -0.2511 | No | ||
90 | ZFPM2 | 460072 | 9005 | 0.002 | -0.2593 | No | ||
91 | CDH6 | 4730541 | 9043 | 0.002 | -0.2613 | No | ||
92 | CHRM1 | 4280619 | 9256 | 0.001 | -0.2728 | No | ||
93 | DCX | 130075 5360025 7050673 | 9306 | 0.001 | -0.2754 | No | ||
94 | BAI3 | 940692 | 9500 | 0.001 | -0.2859 | No | ||
95 | PHYHIP | 1170377 | 9728 | -0.000 | -0.2982 | No | ||
96 | CACNG3 | 520093 | 9732 | -0.000 | -0.2984 | No | ||
97 | C1QTNF7 | 2970619 | 9734 | -0.000 | -0.2984 | No | ||
98 | EDN1 | 1770047 | 9775 | -0.000 | -0.3006 | No | ||
99 | PBX1 | 6660301 | 9823 | -0.000 | -0.3031 | No | ||
100 | PTHLH | 5290739 | 9842 | -0.000 | -0.3041 | No | ||
101 | NEXN | 1240017 5290047 | 10118 | -0.001 | -0.3190 | No | ||
102 | YWHAE | 5310435 | 10135 | -0.001 | -0.3199 | No | ||
103 | NKX2-8 | 50022 | 10186 | -0.001 | -0.3225 | No | ||
104 | SGK2 | 1850070 | 10306 | -0.002 | -0.3290 | No | ||
105 | ZIC3 | 380020 | 10740 | -0.003 | -0.3524 | No | ||
106 | NRXN3 | 1400546 3360471 | 10911 | -0.004 | -0.3616 | No | ||
107 | CDH13 | 5130368 5340114 | 10944 | -0.004 | -0.3632 | No | ||
108 | ICAM4 | 6770053 | 10978 | -0.004 | -0.3649 | No | ||
109 | DEPDC2 | 5220102 | 11266 | -0.005 | -0.3804 | No | ||
110 | DSCR1L1 | 940438 | 11352 | -0.005 | -0.3849 | No | ||
111 | TFEC | 1170722 | 11489 | -0.006 | -0.3922 | No | ||
112 | PI15 | 3840133 | 11541 | -0.006 | -0.3949 | No | ||
113 | CREB5 | 2320368 | 11672 | -0.006 | -0.4018 | No | ||
114 | SLC25A18 | 4540047 | 11911 | -0.007 | -0.4146 | No | ||
115 | CDON | 540204 | 11918 | -0.008 | -0.4148 | No | ||
116 | MRGPRF | 4780746 | 11966 | -0.008 | -0.4172 | No | ||
117 | RARB | 430139 1410138 | 12049 | -0.008 | -0.4215 | No | ||
118 | GFRA3 | 6510609 | 12069 | -0.008 | -0.4223 | No | ||
119 | BNC2 | 4810603 | 12209 | -0.009 | -0.4297 | No | ||
120 | GREM1 | 3940180 | 12219 | -0.009 | -0.4300 | No | ||
121 | JMJD1C | 940575 2120025 | 12357 | -0.010 | -0.4373 | No | ||
122 | MEF2C | 670025 780338 | 12418 | -0.010 | -0.4403 | No | ||
123 | TLR1 | 1410524 | 12692 | -0.011 | -0.4549 | No | ||
124 | CPEB3 | 3940164 | 12700 | -0.011 | -0.4551 | No | ||
125 | KLF15 | 4230164 | 12771 | -0.012 | -0.4587 | No | ||
126 | TPBG | 630161 | 13069 | -0.014 | -0.4745 | No | ||
127 | SPAG7 | 4560524 | 13072 | -0.014 | -0.4744 | No | ||
128 | TSGA10 | 450594 3130435 4920093 | 13139 | -0.015 | -0.4777 | No | ||
129 | POU3F1 | 3710022 | 13314 | -0.016 | -0.4868 | No | ||
130 | ARHGEF2 | 3360577 | 13426 | -0.017 | -0.4925 | No | ||
131 | KLF12 | 1660095 4810288 5340546 6520286 | 13474 | -0.018 | -0.4947 | No | ||
132 | MEIS1 | 1400575 | 13595 | -0.019 | -0.5009 | No | ||
133 | SH3BGRL2 | 1780239 | 13606 | -0.019 | -0.5010 | No | ||
134 | HOXA6 | 2340333 | 13812 | -0.022 | -0.5117 | No | ||
135 | PHACTR3 | 3850435 5900445 | 13954 | -0.024 | -0.5189 | No | ||
136 | PLCD4 | 6450040 | 14008 | -0.025 | -0.5213 | No | ||
137 | RAB6B | 5860121 | 14163 | -0.028 | -0.5292 | No | ||
138 | TRDN | 1580411 | 14202 | -0.029 | -0.5307 | No | ||
139 | TBR1 | 5130053 | 14207 | -0.029 | -0.5303 | No | ||
140 | SOX5 | 2370576 2900167 3190128 5050528 | 14297 | -0.031 | -0.5346 | No | ||
141 | NCAM1 | 3140026 | 14373 | -0.033 | -0.5380 | No | ||
142 | IRX3 | 4200112 | 14498 | -0.035 | -0.5441 | No | ||
143 | LUZP1 | 940075 4280458 6180070 | 14608 | -0.038 | -0.5493 | No | ||
144 | CDX2 | 3850349 | 14621 | -0.039 | -0.5492 | No | ||
145 | ELMO3 | 110372 2640019 | 14691 | -0.041 | -0.5522 | No | ||
146 | BCL9 | 7100112 | 14784 | -0.045 | -0.5563 | No | ||
147 | ITGA10 | 6330438 | 15171 | -0.065 | -0.5760 | No | ||
148 | LAMA3 | 1190131 5290239 | 15380 | -0.078 | -0.5858 | No | ||
149 | TCF1 | 5390022 | 15393 | -0.079 | -0.5850 | No | ||
150 | BPGM | 5080520 | 15423 | -0.083 | -0.5850 | No | ||
151 | ZIC4 | 1500082 | 15644 | -0.104 | -0.5949 | No | ||
152 | ATF2 | 2260348 2480441 | 15731 | -0.113 | -0.5974 | No | ||
153 | RKHD1 | 6860577 | 15745 | -0.114 | -0.5960 | No | ||
154 | SLC4A7 | 2370056 | 15772 | -0.118 | -0.5951 | No | ||
155 | ELAVL4 | 50735 3360086 5220167 | 15832 | -0.126 | -0.5960 | No | ||
156 | GRK6 | 1500053 | 15906 | -0.135 | -0.5974 | No | ||
157 | RORA | 380164 5220215 | 15921 | -0.137 | -0.5955 | No | ||
158 | TFB1M | 2190110 | 15968 | -0.143 | -0.5953 | No | ||
159 | MAP2K5 | 2030440 | 16064 | -0.156 | -0.5975 | No | ||
160 | PDLIM1 | 450100 | 16117 | -0.165 | -0.5972 | No | ||
161 | PANK1 | 670091 6220605 | 16261 | -0.186 | -0.6014 | No | ||
162 | BRUNOL4 | 4490452 5080451 | 16269 | -0.187 | -0.5982 | No | ||
163 | CREM | 840156 6380438 6660041 6660168 | 16364 | -0.204 | -0.5995 | No | ||
164 | TOP1 | 770471 4060632 6650324 | 16424 | -0.215 | -0.5986 | No | ||
165 | SERTAD4 | 130593 | 16514 | -0.230 | -0.5990 | No | ||
166 | ADD3 | 4150739 5390600 | 16573 | -0.243 | -0.5976 | No | ||
167 | MAP4K3 | 5390551 | 16794 | -0.284 | -0.6041 | No | ||
168 | PEA15 | 4590685 | 16911 | -0.315 | -0.6044 | No | ||
169 | PTEN | 3390064 | 17072 | -0.362 | -0.6062 | Yes | ||
170 | TCTA | 2680687 | 17217 | -0.420 | -0.6061 | Yes | ||
171 | TCF12 | 3610324 7000156 | 17226 | -0.423 | -0.5985 | Yes | ||
172 | POLH | 2690528 | 17311 | -0.459 | -0.5943 | Yes | ||
173 | HNRPA0 | 2680048 | 17550 | -0.569 | -0.5964 | Yes | ||
174 | HOXA7 | 5910152 | 17729 | -0.661 | -0.5935 | Yes | ||
175 | SOX4 | 2260091 | 17765 | -0.693 | -0.5822 | Yes | ||
176 | PREP | 6220292 | 17848 | -0.750 | -0.5724 | Yes | ||
177 | IRF2BP1 | 3170019 | 17851 | -0.753 | -0.5582 | Yes | ||
178 | AGPAT4 | 6040079 | 17883 | -0.777 | -0.5452 | Yes | ||
179 | GABARAP | 1450286 | 17920 | -0.802 | -0.5319 | Yes | ||
180 | BRD2 | 1450300 5340484 6100605 | 18040 | -0.926 | -0.5207 | Yes | ||
181 | GADD45A | 2900717 | 18099 | -1.001 | -0.5049 | Yes | ||
182 | MAP3K3 | 610685 | 18205 | -1.159 | -0.4885 | Yes | ||
183 | EVA1 | 5690538 | 18228 | -1.211 | -0.4667 | Yes | ||
184 | HSD11B1 | 450066 5550408 | 18314 | -1.402 | -0.4447 | Yes | ||
185 | CTLA4 | 6590537 | 18369 | -1.563 | -0.4179 | Yes | ||
186 | MAP4K2 | 4200037 | 18375 | -1.598 | -0.3878 | Yes | ||
187 | HBP1 | 2510102 3130010 4210619 | 18428 | -1.800 | -0.3565 | Yes | ||
188 | IL16 | 3850168 | 18515 | -2.441 | -0.3148 | Yes | ||
189 | CCR7 | 2060687 | 18568 | -3.010 | -0.2604 | Yes | ||
190 | BCL6 | 940100 | 18581 | -3.177 | -0.2007 | Yes | ||
191 | BTG1 | 4200735 6040131 6200133 | 18610 | -4.873 | -0.1096 | Yes | ||
192 | RHOA | 580142 5900131 5340450 | 18614 | -5.784 | 0.0001 | Yes |