Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$E2F_Q3 |
Enrichment Score (ES) | 0.5448863 |
Normalized Enrichment Score (NES) | 1.292469 |
Nominal p-value | 0.0464 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HNRPA1 | 4670398 5050687 | 57 | 3.108 | 0.0636 | Yes | ||
2 | TFRC | 4050551 | 123 | 2.289 | 0.1092 | Yes | ||
3 | MCM6 | 60092 540181 6510110 | 127 | 2.248 | 0.1573 | Yes | ||
4 | CDC6 | 4570296 5360600 | 153 | 2.049 | 0.1999 | Yes | ||
5 | DPYSL2 | 2100427 3130112 5700324 | 166 | 1.977 | 0.2417 | Yes | ||
6 | GCH1 | 670364 6550358 | 170 | 1.958 | 0.2835 | Yes | ||
7 | NCL | 2360463 4540279 | 341 | 1.422 | 0.3048 | Yes | ||
8 | MCM4 | 2760673 5420711 | 342 | 1.420 | 0.3353 | Yes | ||
9 | TCP1 | 2450100 5130524 | 431 | 1.221 | 0.3567 | Yes | ||
10 | SHMT1 | 5900132 | 683 | 0.936 | 0.3632 | Yes | ||
11 | ABCF2 | 630040 3140035 6450601 | 714 | 0.919 | 0.3813 | Yes | ||
12 | RBBP7 | 430113 450450 2370309 | 786 | 0.864 | 0.3960 | Yes | ||
13 | SLC25A3 | 670112 | 850 | 0.814 | 0.4101 | Yes | ||
14 | IMPDH2 | 5220138 | 874 | 0.797 | 0.4259 | Yes | ||
15 | RFC1 | 1190673 | 882 | 0.785 | 0.4424 | Yes | ||
16 | UNG | 3130110 6100364 | 1073 | 0.643 | 0.4459 | Yes | ||
17 | APRIN | 2810050 | 1166 | 0.595 | 0.4537 | Yes | ||
18 | HIST1H2BK | 6130433 | 1182 | 0.587 | 0.4655 | Yes | ||
19 | HMGN2 | 3140091 | 1250 | 0.558 | 0.4738 | Yes | ||
20 | PRPS1 | 6350129 | 1321 | 0.529 | 0.4814 | Yes | ||
21 | PIAS1 | 5340301 | 1436 | 0.484 | 0.4856 | Yes | ||
22 | E2F1 | 5360093 | 1439 | 0.484 | 0.4959 | Yes | ||
23 | DLST | 2320722 | 1488 | 0.461 | 0.5032 | Yes | ||
24 | OLFML3 | 7100463 | 1630 | 0.413 | 0.5044 | Yes | ||
25 | NASP | 2260139 2940369 5130707 | 1657 | 0.404 | 0.5117 | Yes | ||
26 | LIG1 | 1980438 4540112 5570609 | 1700 | 0.391 | 0.5178 | Yes | ||
27 | ZCCHC8 | 2260332 2350487 | 1808 | 0.360 | 0.5197 | Yes | ||
28 | DNAJC11 | 360465 3390215 | 1866 | 0.344 | 0.5240 | Yes | ||
29 | BAT3 | 1990594 | 1907 | 0.332 | 0.5289 | Yes | ||
30 | SFRS2 | 50707 380593 | 1912 | 0.330 | 0.5358 | Yes | ||
31 | PPP1R8 | 6290292 | 1965 | 0.318 | 0.5398 | Yes | ||
32 | MCM3 | 5570068 | 2036 | 0.300 | 0.5425 | Yes | ||
33 | SLC38A1 | 520465 | 2110 | 0.281 | 0.5445 | Yes | ||
34 | TBX6 | 4730139 6840647 | 2295 | 0.237 | 0.5397 | Yes | ||
35 | POLA2 | 940519 | 2355 | 0.226 | 0.5413 | Yes | ||
36 | DNMT1 | 2260097 | 2456 | 0.205 | 0.5403 | Yes | ||
37 | RBBP4 | 6650528 | 2589 | 0.182 | 0.5371 | Yes | ||
38 | MCM7 | 3290292 5220056 | 2682 | 0.168 | 0.5357 | Yes | ||
39 | GMNN | 2630148 | 2742 | 0.159 | 0.5359 | Yes | ||
40 | EPHB2 | 1090288 1410377 2100541 | 2761 | 0.157 | 0.5383 | Yes | ||
41 | STMN1 | 1990717 | 2854 | 0.145 | 0.5365 | Yes | ||
42 | RANBP1 | 430215 1090180 | 2860 | 0.145 | 0.5393 | Yes | ||
43 | CLTA | 450010 | 2911 | 0.138 | 0.5395 | Yes | ||
44 | KCNA1 | 2030594 | 2948 | 0.135 | 0.5405 | Yes | ||
45 | PHF15 | 6550066 6860673 | 2960 | 0.133 | 0.5427 | Yes | ||
46 | CPNE5 | 6380673 | 2974 | 0.133 | 0.5449 | Yes | ||
47 | KPNB1 | 1690138 | 3047 | 0.126 | 0.5437 | No | ||
48 | MCM2 | 5050139 | 3131 | 0.118 | 0.5417 | No | ||
49 | SNPH | 2680484 | 3475 | 0.087 | 0.5250 | No | ||
50 | NDUFA11 | 3780333 | 3489 | 0.086 | 0.5262 | No | ||
51 | ERBB2IP | 580253 1090672 | 3517 | 0.084 | 0.5265 | No | ||
52 | PAPOLG | 2470400 | 3539 | 0.082 | 0.5271 | No | ||
53 | STAG2 | 4540132 | 3554 | 0.081 | 0.5281 | No | ||
54 | CDC25A | 3800184 | 3629 | 0.076 | 0.5257 | No | ||
55 | ADAMTS2 | 2650025 6370133 6840670 | 3752 | 0.067 | 0.5206 | No | ||
56 | LASP1 | 1690528 2190341 6420341 | 3803 | 0.064 | 0.5192 | No | ||
57 | SSBP3 | 870717 1050377 7040551 | 3872 | 0.061 | 0.5168 | No | ||
58 | CNOT3 | 130519 4480292 1990609 | 3985 | 0.055 | 0.5120 | No | ||
59 | CDCA7 | 3060097 | 4164 | 0.047 | 0.5033 | No | ||
60 | RAD51 | 6110450 6980280 | 4169 | 0.047 | 0.5041 | No | ||
61 | KCND2 | 1170128 2100112 | 4285 | 0.043 | 0.4988 | No | ||
62 | KLF4 | 1850022 3830239 5570750 | 4373 | 0.041 | 0.4950 | No | ||
63 | AP4M1 | 70609 3440128 | 4493 | 0.038 | 0.4894 | No | ||
64 | RHD | 4050168 | 4643 | 0.034 | 0.4820 | No | ||
65 | CDC45L | 70537 3130114 | 4662 | 0.034 | 0.4818 | No | ||
66 | PRKDC | 1400072 4230541 | 4834 | 0.030 | 0.4732 | No | ||
67 | HS6ST3 | 5910138 | 4851 | 0.030 | 0.4730 | No | ||
68 | ATRX | 2340039 3610132 4210373 | 4867 | 0.030 | 0.4728 | No | ||
69 | PAQR4 | 730736 | 4916 | 0.029 | 0.4708 | No | ||
70 | SEMA5A | 6200110 6520435 | 4968 | 0.028 | 0.4687 | No | ||
71 | E2F3 | 50162 460180 | 5098 | 0.026 | 0.4622 | No | ||
72 | ARID4A | 520156 1050707 | 5122 | 0.026 | 0.4615 | No | ||
73 | GRIK2 | 4610164 | 5344 | 0.023 | 0.4501 | No | ||
74 | CTDSP1 | 6650215 6940731 | 5626 | 0.020 | 0.4353 | No | ||
75 | SALL1 | 5420020 7050195 | 5642 | 0.020 | 0.4349 | No | ||
76 | NRP2 | 4070400 5860041 6650446 | 6000 | 0.016 | 0.4159 | No | ||
77 | FBXO5 | 2630551 | 6593 | 0.012 | 0.3841 | No | ||
78 | STK35 | 2360121 | 6695 | 0.011 | 0.3789 | No | ||
79 | MRPL18 | 6560341 | 6911 | 0.010 | 0.3675 | No | ||
80 | HNRPD | 4120021 | 7164 | 0.009 | 0.3540 | No | ||
81 | ARHGAP6 | 2060121 | 7460 | 0.008 | 0.3382 | No | ||
82 | TOPBP1 | 6020333 | 7521 | 0.007 | 0.3351 | No | ||
83 | UFD1L | 870020 | 7546 | 0.007 | 0.3340 | No | ||
84 | HIST1H1D | 3440446 | 7974 | 0.006 | 0.3110 | No | ||
85 | POLE2 | 6110041 | 8218 | 0.005 | 0.2979 | No | ||
86 | NPR3 | 1580239 | 8419 | 0.004 | 0.2872 | No | ||
87 | PODN | 3710068 | 8511 | 0.004 | 0.2823 | No | ||
88 | NUP153 | 7000452 | 9036 | 0.002 | 0.2540 | No | ||
89 | ONECUT1 | 6450136 | 9341 | 0.001 | 0.2376 | No | ||
90 | AP1S2 | 780279 4280707 | 9355 | 0.001 | 0.2369 | No | ||
91 | TREX2 | 4920707 | 9473 | 0.001 | 0.2306 | No | ||
92 | TBX3 | 2570672 | 10327 | -0.002 | 0.1844 | No | ||
93 | SEZ6 | 3450722 | 10344 | -0.002 | 0.1836 | No | ||
94 | PCSK1 | 2350148 | 10601 | -0.003 | 0.1698 | No | ||
95 | IPO7 | 2190746 | 10678 | -0.003 | 0.1658 | No | ||
96 | CACNA1G | 3060161 4810706 5550722 | 10720 | -0.003 | 0.1636 | No | ||
97 | EPHB1 | 4610056 | 10898 | -0.004 | 0.1541 | No | ||
98 | BARHL1 | 4210113 | 11107 | -0.004 | 0.1429 | No | ||
99 | ORC1L | 2370328 6110390 | 11186 | -0.005 | 0.1388 | No | ||
100 | FMO4 | 360735 | 11247 | -0.005 | 0.1357 | No | ||
101 | ASCL1 | 6650100 | 11377 | -0.005 | 0.1288 | No | ||
102 | PEG3 | 3710020 | 11485 | -0.006 | 0.1231 | No | ||
103 | SMAD6 | 870504 | 12013 | -0.008 | 0.0948 | No | ||
104 | CASP8AP2 | 5910593 | 12227 | -0.009 | 0.0834 | No | ||
105 | WEE1 | 3390070 | 13018 | -0.014 | 0.0410 | No | ||
106 | LHX5 | 2350097 | 13191 | -0.015 | 0.0320 | No | ||
107 | ADCY8 | 6760519 | 13215 | -0.015 | 0.0310 | No | ||
108 | DMD | 1740041 3990332 | 13276 | -0.016 | 0.0281 | No | ||
109 | CBX5 | 3830072 6290167 | 13487 | -0.018 | 0.0172 | No | ||
110 | MEIS1 | 1400575 | 13595 | -0.019 | 0.0118 | No | ||
111 | SLC6A4 | 2230372 | 13655 | -0.020 | 0.0090 | No | ||
112 | DDB2 | 3520341 4610168 4850184 4920717 | 13836 | -0.023 | -0.0003 | No | ||
113 | NOL4 | 5050446 5360519 | 13842 | -0.023 | -0.0000 | No | ||
114 | TRIM47 | 5080717 | 14111 | -0.027 | -0.0140 | No | ||
115 | UXT | 110019 5080066 | 14276 | -0.031 | -0.0222 | No | ||
116 | JPH1 | 610739 | 14329 | -0.032 | -0.0243 | No | ||
117 | MCM8 | 6130743 | 14349 | -0.032 | -0.0247 | No | ||
118 | INSM1 | 3450671 | 14946 | -0.053 | -0.0558 | No | ||
119 | MDGA1 | 1170139 | 15050 | -0.057 | -0.0602 | No | ||
120 | ATAD2 | 870242 2260687 | 15205 | -0.067 | -0.0671 | No | ||
121 | PVRL1 | 2570167 5220519 5890500 3190309 | 15320 | -0.074 | -0.0716 | No | ||
122 | H2AFZ | 1470168 | 15338 | -0.075 | -0.0709 | No | ||
123 | HIST1H2AH | 3710333 | 15718 | -0.111 | -0.0891 | No | ||
124 | E2F7 | 4200056 | 15752 | -0.115 | -0.0884 | No | ||
125 | ATE1 | 290491 6940722 | 15858 | -0.128 | -0.0913 | No | ||
126 | ING3 | 110438 2060390 | 15975 | -0.145 | -0.0945 | No | ||
127 | KLF5 | 3840348 | 16019 | -0.150 | -0.0936 | No | ||
128 | PLK4 | 430162 5720110 | 16081 | -0.159 | -0.0935 | No | ||
129 | EZH2 | 6130605 6380524 | 16236 | -0.182 | -0.0979 | No | ||
130 | PCSK4 | 130687 670711 3170075 6400411 | 16358 | -0.203 | -0.1001 | No | ||
131 | USP1 | 2760541 5690438 6220673 | 16388 | -0.207 | -0.0973 | No | ||
132 | MAT2A | 4070026 4730079 6020280 | 16421 | -0.215 | -0.0944 | No | ||
133 | FLI1 | 3990142 | 16746 | -0.273 | -0.1061 | No | ||
134 | CTCF | 5340017 | 16777 | -0.280 | -0.1017 | No | ||
135 | SFRS1 | 2360440 | 16829 | -0.295 | -0.0981 | No | ||
136 | PCNA | 940754 | 16965 | -0.328 | -0.0984 | No | ||
137 | SLC25A14 | 4760180 | 17263 | -0.438 | -0.1051 | No | ||
138 | PPP1CC | 6380300 2510647 | 17334 | -0.473 | -0.0987 | No | ||
139 | MAZ | 3360121 6940750 | 17389 | -0.497 | -0.0910 | No | ||
140 | HTF9C | 3190048 4120132 | 17477 | -0.533 | -0.0842 | No | ||
141 | PHF13 | 450435 | 17483 | -0.535 | -0.0730 | No | ||
142 | PIM1 | 630047 | 17505 | -0.548 | -0.0624 | No | ||
143 | PHF12 | 870400 3130687 | 17745 | -0.678 | -0.0608 | No | ||
144 | RAB11B | 3990609 | 17899 | -0.786 | -0.0522 | No | ||
145 | MXD3 | 6220014 | 17936 | -0.815 | -0.0367 | No | ||
146 | SYT11 | 630433 | 18118 | -1.030 | -0.0244 | No | ||
147 | DCK | 6900411 | 18512 | -2.390 | 0.0056 | No |