Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$CMYB_01 |
Enrichment Score (ES) | 0.55425256 |
Normalized Enrichment Score (NES) | 1.3397963 |
Nominal p-value | 0.023569023 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 6 | 5.043 | 0.0803 | Yes | ||
2 | TPM3 | 670600 3170296 5670167 6650471 | 19 | 4.650 | 0.1541 | Yes | ||
3 | PPP2R4 | 670280 2900097 | 37 | 3.665 | 0.2118 | Yes | ||
4 | HES6 | 540411 6550504 | 45 | 3.458 | 0.2667 | Yes | ||
5 | RTN4 | 50725 630647 870097 870184 | 96 | 2.577 | 0.3052 | Yes | ||
6 | FBXO34 | 4010671 5700647 6450026 | 175 | 1.926 | 0.3318 | Yes | ||
7 | DTX1 | 5900372 | 206 | 1.837 | 0.3596 | Yes | ||
8 | HIP2 | 2810095 3990369 4120301 | 270 | 1.642 | 0.3825 | Yes | ||
9 | ATF5 | 5670685 | 304 | 1.513 | 0.4049 | Yes | ||
10 | SH3KBP1 | 670102 2850458 7000309 | 415 | 1.267 | 0.4192 | Yes | ||
11 | SCN5A | 4070017 | 423 | 1.234 | 0.4385 | Yes | ||
12 | LYAR | 7000402 | 461 | 1.171 | 0.4553 | Yes | ||
13 | HOXB4 | 540131 | 471 | 1.159 | 0.4733 | Yes | ||
14 | PIK3R3 | 1770333 | 515 | 1.100 | 0.4886 | Yes | ||
15 | RUVBL2 | 1190377 | 601 | 1.010 | 0.5001 | Yes | ||
16 | DLX1 | 360168 | 662 | 0.950 | 0.5121 | Yes | ||
17 | UBE2M | 2450215 | 711 | 0.919 | 0.5242 | Yes | ||
18 | NLGN2 | 5900592 | 857 | 0.809 | 0.5293 | Yes | ||
19 | PHF7 | 1510519 | 875 | 0.795 | 0.5411 | Yes | ||
20 | HIST1H1A | 1450131 | 1113 | 0.618 | 0.5381 | Yes | ||
21 | ARL1 | 450619 | 1150 | 0.600 | 0.5458 | Yes | ||
22 | ZNF148 | 6420403 | 1169 | 0.591 | 0.5543 | Yes | ||
23 | BAP1 | 3830131 | 1465 | 0.472 | 0.5458 | No | ||
24 | MORF4L2 | 6450133 | 1725 | 0.384 | 0.5379 | No | ||
25 | DAP3 | 1660528 2120039 5420593 | 1868 | 0.343 | 0.5357 | No | ||
26 | NDST2 | 6290711 | 1911 | 0.330 | 0.5387 | No | ||
27 | VAPA | 2480594 | 1974 | 0.316 | 0.5404 | No | ||
28 | BCL9L | 6940053 | 2123 | 0.279 | 0.5369 | No | ||
29 | ABHD2 | 4850504 6840010 | 2267 | 0.244 | 0.5330 | No | ||
30 | SNRPD1 | 4480162 | 2327 | 0.231 | 0.5335 | No | ||
31 | TYRO3 | 3130193 | 2599 | 0.180 | 0.5217 | No | ||
32 | ROCK1 | 130044 | 2627 | 0.176 | 0.5231 | No | ||
33 | PRR3 | 3440112 | 2687 | 0.168 | 0.5226 | No | ||
34 | XPO5 | 2850286 | 2744 | 0.159 | 0.5221 | No | ||
35 | YWHAZ | 1230717 | 2828 | 0.149 | 0.5199 | No | ||
36 | STMN1 | 1990717 | 2854 | 0.145 | 0.5209 | No | ||
37 | RANBP1 | 430215 1090180 | 2860 | 0.145 | 0.5230 | No | ||
38 | PHF15 | 6550066 6860673 | 2960 | 0.133 | 0.5197 | No | ||
39 | KPNB1 | 1690138 | 3047 | 0.126 | 0.5171 | No | ||
40 | RBM6 | 840279 3840563 4780129 6020446 | 3276 | 0.104 | 0.5064 | No | ||
41 | RPL4 | 2940014 5420324 | 3322 | 0.099 | 0.5055 | No | ||
42 | RBBP6 | 2320129 | 3332 | 0.098 | 0.5066 | No | ||
43 | NR2E1 | 4730288 | 3493 | 0.085 | 0.4993 | No | ||
44 | PAPOLG | 2470400 | 3539 | 0.082 | 0.4982 | No | ||
45 | STAG2 | 4540132 | 3554 | 0.081 | 0.4987 | No | ||
46 | EGR3 | 6940128 | 3564 | 0.080 | 0.4995 | No | ||
47 | SPAG9 | 580497 2510180 4210685 | 3898 | 0.060 | 0.4825 | No | ||
48 | MXI1 | 5050064 5130484 | 4107 | 0.049 | 0.4720 | No | ||
49 | BHLHB2 | 7040603 | 4158 | 0.048 | 0.4700 | No | ||
50 | NUP62 | 1240128 | 4272 | 0.044 | 0.4646 | No | ||
51 | ARMET | 5130670 | 4591 | 0.036 | 0.4479 | No | ||
52 | MFN1 | 5080546 6200292 | 4963 | 0.028 | 0.4283 | No | ||
53 | E2F3 | 50162 460180 | 5098 | 0.026 | 0.4214 | No | ||
54 | HOXB3 | 520292 | 5473 | 0.021 | 0.4015 | No | ||
55 | IL4 | 6020537 | 5571 | 0.020 | 0.3966 | No | ||
56 | HR | 2690095 6200300 | 5800 | 0.018 | 0.3845 | No | ||
57 | SULF1 | 430575 | 5945 | 0.017 | 0.3770 | No | ||
58 | DIO1 | 4570279 5290112 5420148 | 5958 | 0.017 | 0.3766 | No | ||
59 | PNRC2 | 3360309 | 6035 | 0.016 | 0.3727 | No | ||
60 | GMPR2 | 4920204 | 6201 | 0.015 | 0.3640 | No | ||
61 | KCNJ15 | 70176 6900750 | 6316 | 0.014 | 0.3581 | No | ||
62 | HOXB8 | 3710450 | 6441 | 0.013 | 0.3516 | No | ||
63 | MORF4L1 | 3190100 | 6578 | 0.012 | 0.3444 | No | ||
64 | GPR21 | 6520152 | 6668 | 0.012 | 0.3398 | No | ||
65 | GPC4 | 5910408 | 6842 | 0.010 | 0.3306 | No | ||
66 | NEUROG3 | 6980451 | 6935 | 0.010 | 0.3257 | No | ||
67 | POGZ | 870348 7040286 | 6941 | 0.010 | 0.3256 | No | ||
68 | UBE2H | 1980142 2970079 | 7004 | 0.010 | 0.3224 | No | ||
69 | PURA | 3870156 | 7035 | 0.010 | 0.3209 | No | ||
70 | ASXL2 | 130670 | 7209 | 0.009 | 0.3117 | No | ||
71 | PHOX2B | 5270075 | 7225 | 0.009 | 0.3110 | No | ||
72 | EYA1 | 1450278 5220390 | 7336 | 0.008 | 0.3052 | No | ||
73 | ACCN2 | 6450465 | 7572 | 0.007 | 0.2926 | No | ||
74 | WNT3 | 2360685 | 7844 | 0.006 | 0.2780 | No | ||
75 | WNT4 | 4150619 | 7931 | 0.006 | 0.2735 | No | ||
76 | BHLHB5 | 6510520 | 7944 | 0.006 | 0.2729 | No | ||
77 | ARHGAP12 | 1050181 | 8231 | 0.005 | 0.2575 | No | ||
78 | LHX1 | 1690100 | 8314 | 0.004 | 0.2531 | No | ||
79 | ATP2B2 | 3780397 | 8446 | 0.004 | 0.2461 | No | ||
80 | FST | 1110600 | 8819 | 0.003 | 0.2260 | No | ||
81 | NR3C2 | 2480324 6400093 | 8916 | 0.002 | 0.2208 | No | ||
82 | PITX2 | 870537 2690139 | 8980 | 0.002 | 0.2174 | No | ||
83 | CITED2 | 5670114 5130088 | 9116 | 0.002 | 0.2101 | No | ||
84 | SCML2 | 3290603 | 9233 | 0.001 | 0.2039 | No | ||
85 | PBX1 | 6660301 | 9823 | -0.000 | 0.1720 | No | ||
86 | ZNF462 | 6900100 | 9853 | -0.000 | 0.1704 | No | ||
87 | FGF12 | 1740446 2360037 | 10144 | -0.001 | 0.1547 | No | ||
88 | CANX | 4760402 | 10215 | -0.002 | 0.1509 | No | ||
89 | TRIM37 | 5270091 | 10520 | -0.002 | 0.1345 | No | ||
90 | PAFAH1B1 | 4230333 6420121 6450066 | 10752 | -0.003 | 0.1220 | No | ||
91 | AP2B1 | 1450184 2370148 3520139 4850593 | 10754 | -0.003 | 0.1220 | No | ||
92 | NEDD8 | 2350722 | 10779 | -0.003 | 0.1208 | No | ||
93 | OAZ2 | 2810110 | 10977 | -0.004 | 0.1102 | No | ||
94 | FGF16 | 4210440 | 11043 | -0.004 | 0.1067 | No | ||
95 | BARHL1 | 4210113 | 11107 | -0.004 | 0.1034 | No | ||
96 | HOXA2 | 2120121 | 11357 | -0.005 | 0.0900 | No | ||
97 | APLN | 6620632 | 11559 | -0.006 | 0.0792 | No | ||
98 | AVPR1B | 1190707 | 11809 | -0.007 | 0.0658 | No | ||
99 | WAC | 5340390 5910164 | 11992 | -0.008 | 0.0561 | No | ||
100 | WNT9B | 50095 | 12060 | -0.008 | 0.0526 | No | ||
101 | CRAT | 540020 2060364 3520148 | 12105 | -0.008 | 0.0503 | No | ||
102 | YBX2 | 3520441 | 12398 | -0.010 | 0.0347 | No | ||
103 | TIMP4 | 6110433 | 12689 | -0.011 | 0.0191 | No | ||
104 | SPATS2 | 2360066 | 13060 | -0.014 | -0.0007 | No | ||
105 | PIK3AP1 | 6760008 | 13120 | -0.015 | -0.0037 | No | ||
106 | MYOG | 3190672 | 13217 | -0.015 | -0.0086 | No | ||
107 | IER5 | 2350575 | 13336 | -0.016 | -0.0147 | No | ||
108 | ERBB4 | 4610400 4810017 | 13431 | -0.017 | -0.0196 | No | ||
109 | ANAPC2 | 6660438 | 13758 | -0.022 | -0.0369 | No | ||
110 | ASH1L | 2510402 5360687 6650685 | 13915 | -0.024 | -0.0449 | No | ||
111 | ETV4 | 2450605 | 13983 | -0.025 | -0.0482 | No | ||
112 | MLLT10 | 1410288 3290142 | 14494 | -0.035 | -0.0753 | No | ||
113 | RBM14 | 5340731 5690315 | 14550 | -0.037 | -0.0776 | No | ||
114 | ODF2 | 1660487 4150484 5690706 6940121 | 14555 | -0.037 | -0.0773 | No | ||
115 | PER1 | 3290315 | 14719 | -0.042 | -0.0854 | No | ||
116 | TOM1 | 940398 2190053 | 14854 | -0.048 | -0.0919 | No | ||
117 | CDC14B | 2320497 3360162 | 14863 | -0.048 | -0.0916 | No | ||
118 | DVL2 | 6110162 | 15006 | -0.055 | -0.0984 | No | ||
119 | NLK | 2030010 2450041 | 15198 | -0.067 | -0.1077 | No | ||
120 | SPINT2 | 2630039 6110519 | 15322 | -0.074 | -0.1132 | No | ||
121 | NRGN | 4280433 | 15326 | -0.075 | -0.1121 | No | ||
122 | ITGA5 | 5550520 | 15331 | -0.075 | -0.1111 | No | ||
123 | TCF1 | 5390022 | 15393 | -0.079 | -0.1132 | No | ||
124 | MGLL | 2030446 4210520 | 15403 | -0.081 | -0.1124 | No | ||
125 | SSNA1 | 360593 | 15570 | -0.096 | -0.1198 | No | ||
126 | ZIC4 | 1500082 | 15644 | -0.104 | -0.1221 | No | ||
127 | GNB2 | 2350053 | 15749 | -0.115 | -0.1259 | No | ||
128 | RNF38 | 1940746 3140133 3840601 | 15787 | -0.120 | -0.1260 | No | ||
129 | SLC39A3 | 3990397 4670494 | 15843 | -0.127 | -0.1270 | No | ||
130 | SP1 | 6590017 | 15961 | -0.142 | -0.1310 | No | ||
131 | POMT1 | 2680047 3440040 6660114 | 16009 | -0.149 | -0.1312 | No | ||
132 | KLF5 | 3840348 | 16019 | -0.150 | -0.1293 | No | ||
133 | PDGFB | 3060440 6370008 | 16044 | -0.153 | -0.1281 | No | ||
134 | AEBP2 | 2970603 | 16442 | -0.219 | -0.1461 | No | ||
135 | USP2 | 1190292 1240253 4850035 | 16553 | -0.238 | -0.1483 | No | ||
136 | ADD3 | 4150739 5390600 | 16573 | -0.243 | -0.1454 | No | ||
137 | DHX30 | 2480494 | 16731 | -0.270 | -0.1496 | No | ||
138 | ARF6 | 3520026 | 16734 | -0.270 | -0.1454 | No | ||
139 | MNAT1 | 730292 2350364 | 16754 | -0.275 | -0.1420 | No | ||
140 | CRSP7 | 4230408 | 16775 | -0.279 | -0.1387 | No | ||
141 | RALY | 940427 1740066 | 16864 | -0.305 | -0.1385 | No | ||
142 | ALDH6A1 | 1770746 | 16886 | -0.310 | -0.1347 | No | ||
143 | NFYA | 5860368 | 17275 | -0.443 | -0.1487 | No | ||
144 | POLH | 2690528 | 17311 | -0.459 | -0.1432 | No | ||
145 | CALM3 | 3390288 | 17313 | -0.460 | -0.1359 | No | ||
146 | HEBP1 | 6100279 | 17357 | -0.484 | -0.1305 | No | ||
147 | CSDA | 2470092 3060053 4780056 | 17377 | -0.493 | -0.1236 | No | ||
148 | NCOA5 | 2060647 | 17386 | -0.496 | -0.1161 | No | ||
149 | MAZ | 3360121 6940750 | 17389 | -0.497 | -0.1083 | No | ||
150 | HTF9C | 3190048 4120132 | 17477 | -0.533 | -0.1045 | No | ||
151 | BRPF1 | 3170139 | 17530 | -0.560 | -0.0983 | No | ||
152 | GSK3B | 5360348 | 17615 | -0.598 | -0.0933 | No | ||
153 | ITPKB | 2900195 7100039 | 17999 | -0.872 | -0.1001 | No | ||
154 | NFE2 | 3710373 | 18067 | -0.961 | -0.0884 | No | ||
155 | IL4I1 | 3190161 | 18072 | -0.965 | -0.0732 | No | ||
156 | MTCH2 | 3780603 6620215 | 18085 | -0.988 | -0.0580 | No | ||
157 | DNAJB1 | 1090041 | 18169 | -1.092 | -0.0450 | No | ||
158 | IGFBP4 | 2680309 5420441 | 18204 | -1.158 | -0.0283 | No | ||
159 | ARNTL | 3170463 | 18352 | -1.518 | -0.0120 | No | ||
160 | EPC1 | 1570050 5290095 6900193 | 18382 | -1.642 | 0.0127 | No |