Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | CTCAGGG,MIR-125B,MIR-125A |
Enrichment Score (ES) | -0.58412504 |
Normalized Enrichment Score (NES) | -1.5308342 |
Nominal p-value | 0.0 |
FDR q-value | 0.13992637 |
FWER p-Value | 0.665 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EMID1 | 3190079 5130152 | 618 | 0.988 | -0.0192 | No | ||
2 | ATP5G2 | 840068 | 684 | 0.934 | -0.0091 | No | ||
3 | PPAT | 1980019 | 740 | 0.895 | 0.0009 | No | ||
4 | RAB3D | 4210253 | 759 | 0.886 | 0.0129 | No | ||
5 | TRAPPC6B | 5080184 5290068 | 878 | 0.788 | 0.0180 | No | ||
6 | BMF | 610102 | 967 | 0.709 | 0.0235 | No | ||
7 | UBE2L3 | 1690707 5900242 | 997 | 0.686 | 0.0319 | No | ||
8 | ITGA9 | 670180 | 1015 | 0.675 | 0.0409 | No | ||
9 | SLC25A15 | 4640368 5550064 | 1107 | 0.621 | 0.0450 | No | ||
10 | EIF2C2 | 770451 | 1325 | 0.528 | 0.0409 | No | ||
11 | FUT4 | 2030324 | 1358 | 0.516 | 0.0466 | No | ||
12 | RPS6KA1 | 4120647 | 1406 | 0.496 | 0.0513 | No | ||
13 | BAP1 | 3830131 | 1465 | 0.472 | 0.0550 | No | ||
14 | NEU1 | 380546 | 1548 | 0.438 | 0.0570 | No | ||
15 | SOCS4 | 1170162 | 1764 | 0.373 | 0.0507 | No | ||
16 | TOR2A | 1400026 | 1798 | 0.363 | 0.0542 | No | ||
17 | ELOVL6 | 5340746 | 1814 | 0.358 | 0.0586 | No | ||
18 | LACTB | 2320139 | 1906 | 0.333 | 0.0585 | No | ||
19 | SLC27A4 | 4060139 | 1918 | 0.329 | 0.0627 | No | ||
20 | PCGF6 | 6420487 | 2030 | 0.302 | 0.0611 | No | ||
21 | APOBEC1 | 4610022 | 2082 | 0.287 | 0.0625 | No | ||
22 | BCL9L | 6940053 | 2123 | 0.279 | 0.0644 | No | ||
23 | ASB6 | 2570600 3850092 | 2133 | 0.275 | 0.0679 | No | ||
24 | MADD | 6100725 7000088 | 2212 | 0.258 | 0.0674 | No | ||
25 | DAG1 | 460053 610341 | 2215 | 0.258 | 0.0711 | No | ||
26 | COPS7B | 2970484 4280022 | 2248 | 0.250 | 0.0730 | No | ||
27 | SUV39H1 | 630112 | 2431 | 0.212 | 0.0662 | No | ||
28 | LOXL1 | 3520537 | 2437 | 0.209 | 0.0690 | No | ||
29 | GRSF1 | 2100184 | 2439 | 0.209 | 0.0720 | No | ||
30 | ZBTB7A | 3780092 | 2476 | 0.201 | 0.0729 | No | ||
31 | OSBPL9 | 2570373 | 2480 | 0.201 | 0.0757 | No | ||
32 | MLF2 | 1940176 | 2672 | 0.170 | 0.0678 | No | ||
33 | MIB1 | 3800537 | 2730 | 0.161 | 0.0670 | No | ||
34 | DYNLT3 | 5570398 | 2780 | 0.155 | 0.0666 | No | ||
35 | PHF15 | 6550066 6860673 | 2960 | 0.133 | 0.0588 | No | ||
36 | PARP14 | 5860487 | 3016 | 0.129 | 0.0577 | No | ||
37 | FAM62A | 5080008 | 3051 | 0.125 | 0.0577 | No | ||
38 | ENTPD4 | 7040288 | 3082 | 0.123 | 0.0578 | No | ||
39 | TRPS1 | 870100 | 3123 | 0.118 | 0.0574 | No | ||
40 | NT5DC1 | 2320463 | 3127 | 0.118 | 0.0590 | No | ||
41 | SLC7A6 | 60687 | 3180 | 0.113 | 0.0578 | No | ||
42 | HOXC6 | 3850133 4920736 | 3257 | 0.106 | 0.0552 | No | ||
43 | SLC7A1 | 2450193 2710241 | 3288 | 0.103 | 0.0551 | No | ||
44 | FBXW4 | 3060577 5670095 | 3318 | 0.100 | 0.0549 | No | ||
45 | ADAM9 | 3360411 | 3330 | 0.099 | 0.0558 | No | ||
46 | EAF1 | 5420039 6550619 | 3401 | 0.092 | 0.0533 | No | ||
47 | NUP210 | 3610161 | 3413 | 0.091 | 0.0540 | No | ||
48 | ZFYVE1 | 60440 | 3429 | 0.091 | 0.0546 | No | ||
49 | MMP11 | 1980619 | 3465 | 0.088 | 0.0539 | No | ||
50 | BAK1 | 6450563 | 3480 | 0.087 | 0.0544 | No | ||
51 | SEMA4F | 3850056 | 3562 | 0.080 | 0.0512 | No | ||
52 | TXNRD1 | 6590446 | 3584 | 0.079 | 0.0512 | No | ||
53 | PODXL | 130717 | 3597 | 0.078 | 0.0517 | No | ||
54 | CNNM1 | 2190433 | 3649 | 0.074 | 0.0500 | No | ||
55 | ANPEP | 6510138 | 3666 | 0.073 | 0.0502 | No | ||
56 | ZNF76 | 3850020 | 3681 | 0.072 | 0.0505 | No | ||
57 | STC1 | 360161 | 3750 | 0.067 | 0.0477 | No | ||
58 | NRM | 520068 | 3759 | 0.066 | 0.0483 | No | ||
59 | PCTK1 | 4560079 | 3779 | 0.065 | 0.0482 | No | ||
60 | ETS1 | 5270278 6450717 6620465 | 3819 | 0.063 | 0.0470 | No | ||
61 | GGTL3 | 1770288 | 3893 | 0.060 | 0.0439 | No | ||
62 | RAB8B | 510692 1980017 3130136 4570739 | 3930 | 0.058 | 0.0428 | No | ||
63 | PPP2R5C | 3310121 6650672 | 3956 | 0.057 | 0.0422 | No | ||
64 | ABR | 610079 1170609 3610195 5670050 | 3979 | 0.056 | 0.0419 | No | ||
65 | ORC2L | 1990470 6510019 | 3989 | 0.055 | 0.0422 | No | ||
66 | SEMA4C | 1980315 | 4018 | 0.053 | 0.0414 | No | ||
67 | APBA2BP | 5700341 | 4044 | 0.052 | 0.0408 | No | ||
68 | LYPLA2 | 1500112 | 4148 | 0.048 | 0.0359 | No | ||
69 | KCNH7 | 7510068 | 4918 | 0.029 | -0.0055 | No | ||
70 | SSTR3 | 5420064 | 4937 | 0.029 | -0.0061 | No | ||
71 | MFN1 | 5080546 6200292 | 4963 | 0.028 | -0.0070 | No | ||
72 | E2F3 | 50162 460180 | 5098 | 0.026 | -0.0139 | No | ||
73 | ADAM11 | 1050008 3130494 | 5104 | 0.026 | -0.0138 | No | ||
74 | SYN2 | 3990593 | 5154 | 0.025 | -0.0161 | No | ||
75 | UBE2R2 | 1230504 | 5218 | 0.024 | -0.0192 | No | ||
76 | SLC35A4 | 2940671 | 5381 | 0.022 | -0.0277 | No | ||
77 | FCHSD1 | 5080050 6450025 | 5415 | 0.022 | -0.0292 | No | ||
78 | SH3BP4 | 3140242 | 5432 | 0.022 | -0.0297 | No | ||
79 | SLC4A4 | 1780075 1850040 4810068 | 5466 | 0.021 | -0.0312 | No | ||
80 | HOXB3 | 520292 | 5473 | 0.021 | -0.0312 | No | ||
81 | IER2 | 2030008 | 5500 | 0.021 | -0.0323 | No | ||
82 | MAP6 | 6860195 | 5590 | 0.020 | -0.0369 | No | ||
83 | CD34 | 6650270 | 5733 | 0.019 | -0.0443 | No | ||
84 | ATP1B4 | 5670546 | 5754 | 0.018 | -0.0451 | No | ||
85 | MAP2K7 | 2260086 | 5805 | 0.018 | -0.0476 | No | ||
86 | SNAI1 | 6590253 | 5831 | 0.018 | -0.0487 | No | ||
87 | PCTP | 6980324 | 6109 | 0.015 | -0.0636 | No | ||
88 | HIVEP2 | 6520538 | 6148 | 0.015 | -0.0654 | No | ||
89 | BSN | 5270347 | 6156 | 0.015 | -0.0656 | No | ||
90 | DVL3 | 360156 5390075 | 6161 | 0.015 | -0.0656 | No | ||
91 | LIFR | 3360068 3830102 | 6409 | 0.013 | -0.0788 | No | ||
92 | OLFML2A | 5890039 | 6412 | 0.013 | -0.0787 | No | ||
93 | BMPR2 | 5340066 6960328 | 6433 | 0.013 | -0.0796 | No | ||
94 | TBX4 | 3060008 | 6471 | 0.013 | -0.0815 | No | ||
95 | DLL4 | 6400403 | 6565 | 0.012 | -0.0863 | No | ||
96 | NCOR2 | 1980575 6550050 | 6630 | 0.012 | -0.0897 | No | ||
97 | RNF121 | 110079 1580279 | 6737 | 0.011 | -0.0953 | No | ||
98 | SLC4A10 | 2060670 | 6768 | 0.011 | -0.0967 | No | ||
99 | VPS4B | 3440332 | 6830 | 0.011 | -0.0999 | No | ||
100 | GPC4 | 5910408 | 6842 | 0.010 | -0.1003 | No | ||
101 | DOCK3 | 3290273 3360497 2850068 | 6851 | 0.010 | -0.1006 | No | ||
102 | GALNT14 | 3990278 2030546 | 7188 | 0.009 | -0.1188 | No | ||
103 | PHOX2B | 5270075 | 7225 | 0.009 | -0.1206 | No | ||
104 | BAI1 | 6350053 | 7307 | 0.008 | -0.1249 | No | ||
105 | SLC8A2 | 6220092 | 7314 | 0.008 | -0.1251 | No | ||
106 | ACCN2 | 6450465 | 7572 | 0.007 | -0.1390 | No | ||
107 | DIRAS1 | 2640270 | 7697 | 0.007 | -0.1456 | No | ||
108 | GOPC | 6620400 | 7850 | 0.006 | -0.1538 | No | ||
109 | ST8SIA4 | 2680605 3060215 | 7922 | 0.006 | -0.1576 | No | ||
110 | EIF5A2 | 7040139 | 7923 | 0.006 | -0.1575 | No | ||
111 | SATB2 | 2470181 | 7962 | 0.006 | -0.1595 | No | ||
112 | NIN | 3450576 5080048 | 7967 | 0.006 | -0.1596 | No | ||
113 | UBE2G1 | 2230546 5420528 7040463 | 8210 | 0.005 | -0.1727 | No | ||
114 | MAP3K10 | 3360168 4850180 | 8277 | 0.005 | -0.1762 | No | ||
115 | STARD13 | 540722 | 8398 | 0.004 | -0.1827 | No | ||
116 | SLC17A7 | 7000037 | 8401 | 0.004 | -0.1828 | No | ||
117 | GRIN2A | 6550538 | 8554 | 0.004 | -0.1910 | No | ||
118 | CGN | 5890139 6370167 6400537 | 8556 | 0.004 | -0.1910 | No | ||
119 | MYT1 | 6770524 | 8692 | 0.003 | -0.1983 | No | ||
120 | HMGB3 | 2940168 | 9465 | 0.001 | -0.2403 | No | ||
121 | GALNT7 | 3990280 | 9483 | 0.001 | -0.2412 | No | ||
122 | SOX11 | 610279 | 9618 | 0.000 | -0.2485 | No | ||
123 | MAMDC2 | 430471 | 9702 | -0.000 | -0.2530 | No | ||
124 | PHYHIP | 1170377 | 9728 | -0.000 | -0.2543 | No | ||
125 | DPF2 | 6980373 | 10125 | -0.001 | -0.2759 | No | ||
126 | RHOQ | 520161 | 10146 | -0.001 | -0.2769 | No | ||
127 | ADD2 | 5910463 | 10152 | -0.001 | -0.2772 | No | ||
128 | IBRDC2 | 5130041 | 10177 | -0.001 | -0.2785 | No | ||
129 | HCN4 | 1050026 | 10218 | -0.002 | -0.2806 | No | ||
130 | CCNJ | 870047 | 10316 | -0.002 | -0.2859 | No | ||
131 | SAMD10 | 1580497 | 10605 | -0.003 | -0.3015 | No | ||
132 | VANGL2 | 70097 870075 | 10606 | -0.003 | -0.3015 | No | ||
133 | PAFAH1B1 | 4230333 6420121 6450066 | 10752 | -0.003 | -0.3093 | No | ||
134 | RBM7 | 5890348 | 10756 | -0.003 | -0.3094 | No | ||
135 | LRFN2 | 6450411 | 10828 | -0.003 | -0.3133 | No | ||
136 | ABHD3 | 2370091 | 10942 | -0.004 | -0.3193 | No | ||
137 | OAZ2 | 2810110 | 10977 | -0.004 | -0.3211 | No | ||
138 | KCNS3 | 4150039 | 11150 | -0.005 | -0.3304 | No | ||
139 | DDX42 | 2060546 | 11610 | -0.006 | -0.3553 | No | ||
140 | M6PR | 2480458 3290593 3840324 | 12240 | -0.009 | -0.3894 | No | ||
141 | TGOLN2 | 4920433 | 12298 | -0.009 | -0.3924 | No | ||
142 | ATOH8 | 4540204 | 12374 | -0.010 | -0.3963 | No | ||
143 | GRB10 | 6980082 | 12405 | -0.010 | -0.3978 | No | ||
144 | SET | 6650286 | 12420 | -0.010 | -0.3984 | No | ||
145 | PAPOLA | 4200286 4850112 | 12665 | -0.011 | -0.4115 | No | ||
146 | CPEB3 | 3940164 | 12700 | -0.011 | -0.4132 | No | ||
147 | PRDM1 | 3170347 3520301 | 12774 | -0.012 | -0.4170 | No | ||
148 | PLXNA1 | 70066 | 12824 | -0.012 | -0.4195 | No | ||
149 | ASB13 | 1090070 | 12897 | -0.013 | -0.4232 | No | ||
150 | ABHD6 | 630717 | 12984 | -0.014 | -0.4277 | No | ||
151 | SLITRK6 | 7320739 | 13144 | -0.015 | -0.4361 | No | ||
152 | RET | 3850746 | 13211 | -0.015 | -0.4395 | No | ||
153 | CSNK2A1 | 1580577 | 13739 | -0.021 | -0.4679 | No | ||
154 | LRP4 | 1740253 | 13940 | -0.024 | -0.4784 | No | ||
155 | MASP1 | 1780619 2900066 | 14040 | -0.026 | -0.4834 | No | ||
156 | FKHL18 | 6370603 | 14055 | -0.026 | -0.4838 | No | ||
157 | RTN2 | 4480538 | 14188 | -0.029 | -0.4906 | No | ||
158 | MTUS1 | 780348 4920609 | 14325 | -0.032 | -0.4975 | No | ||
159 | LNPEP | 1170092 1940093 3120025 | 14564 | -0.037 | -0.5099 | No | ||
160 | KLC2 | 1240048 5340441 | 14568 | -0.037 | -0.5095 | No | ||
161 | ABCC5 | 2100600 5050692 | 14657 | -0.040 | -0.5137 | No | ||
162 | NIPA1 | 380600 | 14728 | -0.043 | -0.5169 | No | ||
163 | MYLK | 4010600 7000364 | 14743 | -0.043 | -0.5171 | No | ||
164 | CACNB1 | 2940427 3710487 | 14786 | -0.045 | -0.5187 | No | ||
165 | SMURF1 | 520609 580647 | 15048 | -0.057 | -0.5321 | No | ||
166 | ITGB3 | 5270463 | 15056 | -0.057 | -0.5316 | No | ||
167 | PPP1CA | 1450722 3140181 1770133 4070092 | 15069 | -0.058 | -0.5314 | No | ||
168 | USP37 | 2470433 | 15071 | -0.058 | -0.5306 | No | ||
169 | USP12 | 6130735 6620280 | 15512 | -0.091 | -0.5532 | No | ||
170 | ZNF385 | 450176 4810358 | 15514 | -0.092 | -0.5519 | No | ||
171 | SLC39A9 | 3940348 | 15560 | -0.095 | -0.5530 | No | ||
172 | UBN1 | 5900195 | 15575 | -0.097 | -0.5524 | No | ||
173 | MKNK2 | 1240020 5270092 | 15588 | -0.098 | -0.5516 | No | ||
174 | SORT1 | 1850242 2320632 3870537 | 15664 | -0.106 | -0.5541 | No | ||
175 | SGPL1 | 4480059 | 15748 | -0.115 | -0.5570 | No | ||
176 | CORO2A | 3840605 6620390 | 16059 | -0.156 | -0.5715 | No | ||
177 | VDR | 130156 510438 | 16112 | -0.164 | -0.5720 | No | ||
178 | SUV420H2 | 4050368 | 16134 | -0.168 | -0.5707 | No | ||
179 | DICER1 | 540286 | 16382 | -0.206 | -0.5811 | Yes | ||
180 | ESRRA | 6550242 | 16407 | -0.211 | -0.5793 | Yes | ||
181 | PTPRF | 1770528 3190044 | 16443 | -0.219 | -0.5781 | Yes | ||
182 | ATP10D | 4850139 | 16446 | -0.219 | -0.5750 | Yes | ||
183 | UBTD1 | 6900315 | 16494 | -0.228 | -0.5742 | Yes | ||
184 | GGA2 | 520451 1240082 2650332 | 16554 | -0.239 | -0.5739 | Yes | ||
185 | PTPN18 | 2640537 | 16555 | -0.239 | -0.5704 | Yes | ||
186 | ATXN1 | 5550156 | 16576 | -0.244 | -0.5680 | Yes | ||
187 | PELI2 | 1940364 | 16597 | -0.248 | -0.5655 | Yes | ||
188 | MXD4 | 4810113 | 16630 | -0.252 | -0.5635 | Yes | ||
189 | SCARB1 | 510441 6770047 | 16633 | -0.253 | -0.5599 | Yes | ||
190 | TBC1D1 | 2510072 | 16644 | -0.255 | -0.5568 | Yes | ||
191 | IRF4 | 610133 | 16700 | -0.265 | -0.5559 | Yes | ||
192 | ETV6 | 610524 | 16718 | -0.268 | -0.5529 | Yes | ||
193 | RFXANK | 4010341 | 16855 | -0.302 | -0.5559 | Yes | ||
194 | SEMA4D | 7050152 | 16910 | -0.315 | -0.5542 | Yes | ||
195 | SMARCD2 | 3830619 | 16926 | -0.318 | -0.5504 | Yes | ||
196 | PHC2 | 1430433 | 16928 | -0.318 | -0.5458 | Yes | ||
197 | MAPK14 | 5290731 | 16936 | -0.320 | -0.5415 | Yes | ||
198 | SYVN1 | 6940594 | 16975 | -0.332 | -0.5387 | Yes | ||
199 | LFNG | 5360711 | 16979 | -0.334 | -0.5340 | Yes | ||
200 | WARS | 2570717 3290139 | 17084 | -0.367 | -0.5343 | Yes | ||
201 | PCSK7 | 6370450 | 17138 | -0.388 | -0.5316 | Yes | ||
202 | BAZ2A | 730184 | 17202 | -0.414 | -0.5289 | Yes | ||
203 | PCQAP | 3060064 6200273 | 17287 | -0.448 | -0.5270 | Yes | ||
204 | TLK2 | 1170161 | 17304 | -0.456 | -0.5212 | Yes | ||
205 | HIC2 | 4010433 | 17372 | -0.492 | -0.5177 | Yes | ||
206 | CASC3 | 5890095 | 17393 | -0.499 | -0.5115 | Yes | ||
207 | MYO18A | 1230333 | 17436 | -0.517 | -0.5062 | Yes | ||
208 | MTMR3 | 1050014 4920180 | 17457 | -0.526 | -0.4996 | Yes | ||
209 | SIRT7 | 5890632 | 17462 | -0.527 | -0.4922 | Yes | ||
210 | BRPF1 | 3170139 | 17530 | -0.560 | -0.4876 | Yes | ||
211 | RHOT2 | 1660053 2120292 | 17657 | -0.622 | -0.4854 | Yes | ||
212 | ABTB1 | 4780086 | 17667 | -0.627 | -0.4768 | Yes | ||
213 | TEF | 1050050 3120397 4060487 | 17678 | -0.631 | -0.4681 | Yes | ||
214 | RNF40 | 3610397 | 17708 | -0.649 | -0.4602 | Yes | ||
215 | DNAJB5 | 2900215 | 17717 | -0.653 | -0.4511 | Yes | ||
216 | MAP3K11 | 7000039 | 17763 | -0.692 | -0.4435 | Yes | ||
217 | DCTN1 | 1450056 6590022 | 17780 | -0.703 | -0.4341 | Yes | ||
218 | CASP2 | 2260692 | 17790 | -0.709 | -0.4242 | Yes | ||
219 | SEMA4B | 110347 | 17797 | -0.715 | -0.4141 | Yes | ||
220 | SERTAD3 | 2810088 | 17815 | -0.728 | -0.4044 | Yes | ||
221 | USP52 | 3710215 6380133 | 17874 | -0.769 | -0.3964 | Yes | ||
222 | STAT3 | 460040 3710341 | 17921 | -0.802 | -0.3872 | Yes | ||
223 | CDC42SE1 | 510037 3780438 | 17961 | -0.837 | -0.3771 | Yes | ||
224 | IHPK1 | 1340053 | 18031 | -0.918 | -0.3675 | Yes | ||
225 | LBH | 70093 | 18081 | -0.978 | -0.3559 | Yes | ||
226 | ANKRD50 | 870543 | 18166 | -1.089 | -0.3445 | Yes | ||
227 | CBX7 | 3940035 | 18219 | -1.193 | -0.3300 | Yes | ||
228 | ZSWIM4 | 6940195 | 18225 | -1.202 | -0.3127 | Yes | ||
229 | KLF13 | 4670563 | 18239 | -1.228 | -0.2955 | Yes | ||
230 | GTPBP2 | 2760750 | 18289 | -1.353 | -0.2784 | Yes | ||
231 | PLAGL2 | 1770148 | 18310 | -1.390 | -0.2592 | Yes | ||
232 | RNF44 | 5910692 | 18317 | -1.410 | -0.2390 | Yes | ||
233 | MCL1 | 1660672 | 18366 | -1.559 | -0.2189 | Yes | ||
234 | ARID3B | 6650008 | 18459 | -1.981 | -0.1950 | Yes | ||
235 | FLOT2 | 50358 4210068 5080397 | 18499 | -2.293 | -0.1637 | Yes | ||
236 | IL16 | 3850168 | 18515 | -2.441 | -0.1289 | Yes | ||
237 | EIF4EBP1 | 60132 5720148 | 18525 | -2.523 | -0.0926 | Yes | ||
238 | SRF | 70139 2320039 | 18583 | -3.247 | -0.0483 | Yes | ||
239 | ST6GAL1 | 2970546 | 18592 | -3.431 | 0.0013 | Yes |