Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D |
Enrichment Score (ES) | -0.59022176 |
Normalized Enrichment Score (NES) | -1.5606079 |
Nominal p-value | 0.0 |
FDR q-value | 0.14430378 |
FWER p-Value | 0.497 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RGMA | 2450711 | 74 | 2.853 | 0.0295 | No | ||
2 | CCND1 | 460524 770309 3120576 6980398 | 90 | 2.631 | 0.0596 | No | ||
3 | SLC6A9 | 2470520 | 204 | 1.842 | 0.0751 | No | ||
4 | PPP3R1 | 1190041 1570487 | 228 | 1.760 | 0.0946 | No | ||
5 | MUTED | 3140452 4610086 4730348 | 230 | 1.748 | 0.1151 | No | ||
6 | INHBB | 2680092 | 661 | 0.950 | 0.1029 | No | ||
7 | LEFTY1 | 3290452 | 678 | 0.938 | 0.1130 | No | ||
8 | RBBP7 | 430113 450450 2370309 | 786 | 0.864 | 0.1174 | No | ||
9 | TNFAIP1 | 6940593 | 788 | 0.863 | 0.1275 | No | ||
10 | SDC1 | 3440471 6350408 | 1070 | 0.645 | 0.1198 | No | ||
11 | APP | 2510053 | 1312 | 0.534 | 0.1129 | No | ||
12 | CXXC6 | 2810168 | 1393 | 0.500 | 0.1145 | No | ||
13 | RPS6KA1 | 4120647 | 1406 | 0.496 | 0.1196 | No | ||
14 | DAZAP2 | 6200102 | 1597 | 0.428 | 0.1143 | No | ||
15 | MBNL2 | 3450707 | 1669 | 0.400 | 0.1152 | No | ||
16 | MRPS25 | 610441 870128 1410368 | 2101 | 0.283 | 0.0951 | No | ||
17 | RPS6KA3 | 1980707 | 2107 | 0.281 | 0.0981 | No | ||
18 | NEK9 | 3440402 | 2232 | 0.254 | 0.0943 | No | ||
19 | AK2 | 4590458 4760195 6110097 | 2317 | 0.233 | 0.0925 | No | ||
20 | CUGBP2 | 6180121 6840139 | 2374 | 0.221 | 0.0921 | No | ||
21 | SS18L1 | 4610180 6550068 | 2413 | 0.215 | 0.0925 | No | ||
22 | SUV39H1 | 630112 | 2431 | 0.212 | 0.0941 | No | ||
23 | ASF1A | 7050020 | 2502 | 0.196 | 0.0926 | No | ||
24 | TRIM36 | 1400600 1980082 5130037 | 2570 | 0.185 | 0.0911 | No | ||
25 | DCUN1D1 | 2360332 | 2586 | 0.183 | 0.0925 | No | ||
26 | PBX3 | 1300424 3710577 6180575 | 2632 | 0.175 | 0.0921 | No | ||
27 | RALGDS | 430463 | 2781 | 0.155 | 0.0859 | No | ||
28 | YWHAZ | 1230717 | 2828 | 0.149 | 0.0851 | No | ||
29 | UBE2J1 | 4070133 | 2918 | 0.137 | 0.0819 | No | ||
30 | YTHDF3 | 4540632 4670717 7040609 | 3007 | 0.130 | 0.0786 | No | ||
31 | TRPS1 | 870100 | 3123 | 0.118 | 0.0738 | No | ||
32 | RAB22A | 110500 3830707 | 3310 | 0.101 | 0.0648 | No | ||
33 | ADAM9 | 3360411 | 3330 | 0.099 | 0.0650 | No | ||
34 | PCDHA7 | 1850019 | 3337 | 0.098 | 0.0658 | No | ||
35 | PFN2 | 730040 5700026 | 3403 | 0.092 | 0.0633 | No | ||
36 | DMTF1 | 5910047 1570497 2480100 6620239 | 3632 | 0.076 | 0.0518 | No | ||
37 | TARDBP | 870390 2350093 | 4036 | 0.052 | 0.0305 | No | ||
38 | ZFP36L2 | 510180 | 4049 | 0.052 | 0.0305 | No | ||
39 | FLT1 | 3830167 4920438 | 4096 | 0.050 | 0.0286 | No | ||
40 | LATS2 | 4480593 6020494 | 4124 | 0.049 | 0.0277 | No | ||
41 | POLQ | 1050053 2190102 | 4146 | 0.048 | 0.0271 | No | ||
42 | CDCA7 | 3060097 | 4164 | 0.047 | 0.0267 | No | ||
43 | DHX40 | 360672 | 4232 | 0.045 | 0.0236 | No | ||
44 | ST8SIA2 | 2680082 | 4314 | 0.043 | 0.0197 | No | ||
45 | LUC7L2 | 1850402 6350088 | 4408 | 0.040 | 0.0151 | No | ||
46 | RABGAP1 | 5050397 | 4468 | 0.038 | 0.0124 | No | ||
47 | RHOC | 2060242 | 4523 | 0.037 | 0.0099 | No | ||
48 | FOXL2 | 5670537 | 4585 | 0.036 | 0.0070 | No | ||
49 | MMP24 | 5340154 | 4586 | 0.036 | 0.0074 | No | ||
50 | RABEP1 | 4760427 6200463 | 4663 | 0.034 | 0.0037 | No | ||
51 | PCAF | 2230161 2570369 6550451 | 4690 | 0.033 | 0.0026 | No | ||
52 | SYNC1 | 580114 | 4694 | 0.033 | 0.0029 | No | ||
53 | NEO1 | 1990154 | 4699 | 0.033 | 0.0030 | No | ||
54 | NFIB | 460450 | 4752 | 0.032 | 0.0006 | No | ||
55 | ARID4B | 730754 6660026 | 4881 | 0.030 | -0.0060 | No | ||
56 | EDNRB | 4280717 6400435 | 4931 | 0.029 | -0.0084 | No | ||
57 | OLFM3 | 580112 1050072 4070204 | 5113 | 0.026 | -0.0179 | No | ||
58 | ARID4A | 520156 1050707 | 5122 | 0.026 | -0.0180 | No | ||
59 | GABPB2 | 6130450 7050735 | 5164 | 0.025 | -0.0200 | No | ||
60 | UBE2R2 | 1230504 | 5218 | 0.024 | -0.0226 | No | ||
61 | NEUROD1 | 3060619 | 5313 | 0.023 | -0.0274 | No | ||
62 | ESR1 | 4060372 5860193 | 5448 | 0.022 | -0.0344 | No | ||
63 | DPYSL5 | 4900333 | 5513 | 0.021 | -0.0377 | No | ||
64 | SLITRK3 | 5910041 | 5731 | 0.019 | -0.0492 | No | ||
65 | RGL1 | 1500097 6900450 | 5824 | 0.018 | -0.0540 | No | ||
66 | FNDC3A | 2690097 3290044 | 5826 | 0.018 | -0.0539 | No | ||
67 | ZKSCAN1 | 6380605 | 5937 | 0.017 | -0.0597 | No | ||
68 | PCDHA1 | 940026 540484 | 6162 | 0.015 | -0.0717 | No | ||
69 | RSBN1 | 7000487 | 6176 | 0.015 | -0.0722 | No | ||
70 | MLLT6 | 3870168 | 6398 | 0.013 | -0.0841 | No | ||
71 | PRRX1 | 4120193 4480390 | 6452 | 0.013 | -0.0868 | No | ||
72 | ECT2 | 3830086 | 6969 | 0.010 | -0.1147 | No | ||
73 | PURA | 3870156 | 7035 | 0.010 | -0.1181 | No | ||
74 | ZBTB4 | 6450441 | 7059 | 0.009 | -0.1193 | No | ||
75 | MYT1L | 5670369 6660403 | 7121 | 0.009 | -0.1225 | No | ||
76 | NPAS3 | 630408 4610066 | 7282 | 0.008 | -0.1311 | No | ||
77 | TLOC1 | 4050309 | 7320 | 0.008 | -0.1330 | No | ||
78 | ETV1 | 70735 2940603 5080463 | 7354 | 0.008 | -0.1347 | No | ||
79 | DRD1 | 430025 | 7424 | 0.008 | -0.1384 | No | ||
80 | PHF6 | 3120632 3990041 | 7665 | 0.007 | -0.1513 | No | ||
81 | LASS6 | 5890576 6520138 | 7673 | 0.007 | -0.1516 | No | ||
82 | BRP44L | 1340605 | 7807 | 0.006 | -0.1588 | No | ||
83 | ARHGEF17 | 2060008 | 8134 | 0.005 | -0.1764 | No | ||
84 | PCDHA3 | 3840402 | 8235 | 0.005 | -0.1818 | No | ||
85 | EPAS1 | 5290156 | 8247 | 0.005 | -0.1824 | No | ||
86 | OSBPL5 | 3840537 6040286 | 8252 | 0.005 | -0.1825 | No | ||
87 | BAMBI | 6650463 | 8310 | 0.005 | -0.1856 | No | ||
88 | ANKRD13C | 5270202 | 8442 | 0.004 | -0.1926 | No | ||
89 | ATP2B2 | 3780397 | 8446 | 0.004 | -0.1928 | No | ||
90 | LHX8 | 5700347 | 8579 | 0.004 | -0.1999 | No | ||
91 | RAD23B | 2190671 | 8683 | 0.003 | -0.2055 | No | ||
92 | PCDHA10 | 3830725 | 8977 | 0.002 | -0.2214 | No | ||
93 | ZFPM2 | 460072 | 9005 | 0.002 | -0.2228 | No | ||
94 | TIPARP | 50397 | 9437 | 0.001 | -0.2462 | No | ||
95 | KCNMA1 | 1450402 | 9448 | 0.001 | -0.2468 | No | ||
96 | ZMYND11 | 630181 2570019 4850138 5360040 | 9589 | 0.000 | -0.2544 | No | ||
97 | LHX6 | 2360731 3360397 | 9697 | -0.000 | -0.2602 | No | ||
98 | SLC2A4 | 540441 | 9929 | -0.001 | -0.2727 | No | ||
99 | VSX1 | 4610605 6650112 | 10053 | -0.001 | -0.2794 | No | ||
100 | PCDHA5 | 2970347 | 10285 | -0.002 | -0.2920 | No | ||
101 | CCNJ | 870047 | 10316 | -0.002 | -0.2936 | No | ||
102 | PCDHA12 | 2810215 | 10586 | -0.003 | -0.3082 | No | ||
103 | PRDM8 | 840746 | 10645 | -0.003 | -0.3113 | No | ||
104 | ALX4 | 3870019 | 10656 | -0.003 | -0.3118 | No | ||
105 | TAOK2 | 110575 6380692 | 10715 | -0.003 | -0.3149 | No | ||
106 | ABCA1 | 6290156 | 10872 | -0.004 | -0.3233 | No | ||
107 | ANK2 | 6510546 | 11257 | -0.005 | -0.3442 | No | ||
108 | SSX2IP | 4610176 | 11292 | -0.005 | -0.3459 | No | ||
109 | PAK7 | 3830164 | 11345 | -0.005 | -0.3487 | No | ||
110 | NR4A3 | 2900021 5860095 5910039 | 11354 | -0.005 | -0.3491 | No | ||
111 | E2F5 | 5860575 | 11547 | -0.006 | -0.3595 | No | ||
112 | VLDLR | 870722 3060047 5340452 6550131 | 11548 | -0.006 | -0.3594 | No | ||
113 | CREB5 | 2320368 | 11672 | -0.006 | -0.3660 | No | ||
114 | ZBTB11 | 6520092 | 11824 | -0.007 | -0.3741 | No | ||
115 | NTN4 | 6940398 | 12052 | -0.008 | -0.3864 | No | ||
116 | PCDHA11 | 1510253 | 12194 | -0.009 | -0.3939 | No | ||
117 | HLF | 2370113 | 12231 | -0.009 | -0.3958 | No | ||
118 | MEF2C | 670025 780338 | 12418 | -0.010 | -0.4058 | No | ||
119 | NEUROD6 | 4670731 | 12492 | -0.010 | -0.4096 | No | ||
120 | PCDHA6 | 780333 2370280 | 12609 | -0.011 | -0.4158 | No | ||
121 | PAPOLA | 4200286 4850112 | 12665 | -0.011 | -0.4187 | No | ||
122 | PLXNA1 | 70066 | 12824 | -0.012 | -0.4271 | No | ||
123 | PLAG1 | 1450142 3870139 6520039 | 12912 | -0.013 | -0.4317 | No | ||
124 | ARHGEF10 | 3120593 6900673 | 12955 | -0.013 | -0.4338 | No | ||
125 | OSBPL8 | 50603 | 12971 | -0.013 | -0.4345 | No | ||
126 | WEE1 | 3390070 | 13018 | -0.014 | -0.4368 | No | ||
127 | MINK1 | 5860647 | 13243 | -0.016 | -0.4488 | No | ||
128 | UBE2B | 4780497 | 13313 | -0.016 | -0.4524 | No | ||
129 | RB1CC1 | 510494 7100072 | 13345 | -0.017 | -0.4538 | No | ||
130 | PGBD5 | 1190047 | 13354 | -0.017 | -0.4541 | No | ||
131 | EPHA2 | 5890056 | 13415 | -0.017 | -0.4571 | No | ||
132 | KLF12 | 1660095 4810288 5340546 6520286 | 13474 | -0.018 | -0.4601 | No | ||
133 | MARCH8 | 60397 | 13629 | -0.020 | -0.4682 | No | ||
134 | TRPV6 | 4010717 | 13700 | -0.021 | -0.4718 | No | ||
135 | RAB11FIP1 | 2470333 | 13848 | -0.023 | -0.4795 | No | ||
136 | PARP8 | 4150204 | 13917 | -0.024 | -0.4829 | No | ||
137 | CYP26B1 | 2630142 | 13978 | -0.025 | -0.4859 | No | ||
138 | RPS6KA5 | 2120563 7040546 | 14078 | -0.026 | -0.4910 | No | ||
139 | DDHD1 | 3450241 3940523 6380156 | 14158 | -0.028 | -0.4949 | No | ||
140 | FGD5 | 3520438 4060500 | 14246 | -0.030 | -0.4993 | No | ||
141 | SENP1 | 6100537 | 14280 | -0.031 | -0.5008 | No | ||
142 | MTUS1 | 780348 4920609 | 14325 | -0.032 | -0.5028 | No | ||
143 | KLHL18 | 4560075 | 14444 | -0.034 | -0.5088 | No | ||
144 | BRMS1L | 6110609 | 14450 | -0.034 | -0.5087 | No | ||
145 | RBL1 | 3130372 | 14714 | -0.042 | -0.5225 | No | ||
146 | KPNA2 | 3450114 | 14715 | -0.042 | -0.5220 | No | ||
147 | NR2C2 | 6100097 | 14738 | -0.043 | -0.5227 | No | ||
148 | PLEKHA3 | 5080068 | 14820 | -0.046 | -0.5265 | No | ||
149 | NR4A2 | 60273 | 14893 | -0.050 | -0.5298 | No | ||
150 | ATAD2 | 870242 2260687 | 15205 | -0.067 | -0.5460 | No | ||
151 | RAB6A | 3840463 4780731 | 15250 | -0.070 | -0.5475 | No | ||
152 | TAL1 | 7040239 | 15279 | -0.072 | -0.5482 | No | ||
153 | RAB11A | 5360079 | 15282 | -0.072 | -0.5475 | No | ||
154 | CRIM1 | 130491 | 15335 | -0.075 | -0.5494 | No | ||
155 | SNF1LK | 6110403 | 15372 | -0.078 | -0.5505 | No | ||
156 | GNB5 | 4480736 6550722 6770463 | 15415 | -0.082 | -0.5518 | No | ||
157 | ZNF385 | 450176 4810358 | 15514 | -0.092 | -0.5560 | No | ||
158 | LEF1 | 2470082 7100288 | 15520 | -0.092 | -0.5552 | No | ||
159 | SAR1B | 2510273 | 15580 | -0.097 | -0.5573 | No | ||
160 | MKNK2 | 1240020 5270092 | 15588 | -0.098 | -0.5565 | No | ||
161 | YPEL2 | 5560609 | 15649 | -0.105 | -0.5586 | No | ||
162 | E2F7 | 4200056 | 15752 | -0.115 | -0.5627 | No | ||
163 | PURB | 5360138 | 15833 | -0.126 | -0.5656 | No | ||
164 | CFL2 | 380239 6200368 | 15913 | -0.135 | -0.5683 | No | ||
165 | SF4 | 3830341 | 15953 | -0.142 | -0.5688 | No | ||
166 | COL23A1 | 2030358 | 15954 | -0.142 | -0.5671 | No | ||
167 | RDBP | 6590044 | 15959 | -0.142 | -0.5657 | No | ||
168 | OXR1 | 2370039 3190706 | 15980 | -0.145 | -0.5650 | No | ||
169 | MNT | 4920575 | 16026 | -0.150 | -0.5657 | No | ||
170 | DNAJA2 | 2630253 6860358 | 16102 | -0.162 | -0.5679 | No | ||
171 | CRK | 1230162 4780128 | 16356 | -0.203 | -0.5793 | No | ||
172 | AEBP2 | 2970603 | 16442 | -0.219 | -0.5813 | No | ||
173 | MECP2 | 1940450 | 16526 | -0.233 | -0.5831 | No | ||
174 | ATXN1 | 5550156 | 16576 | -0.244 | -0.5829 | No | ||
175 | ORMDL3 | 1340711 | 16606 | -0.249 | -0.5815 | No | ||
176 | FRMD4A | 2190176 | 16646 | -0.255 | -0.5807 | No | ||
177 | SMAD2 | 4200592 | 16785 | -0.281 | -0.5849 | No | ||
178 | RNF6 | 2640035 | 16826 | -0.294 | -0.5836 | No | ||
179 | PERQ1 | 1340164 | 16937 | -0.320 | -0.5858 | No | ||
180 | BCL11A | 6860369 | 16955 | -0.325 | -0.5829 | No | ||
181 | TUSC2 | 1580253 | 17091 | -0.371 | -0.5859 | Yes | ||
182 | IQWD1 | 160475 | 17108 | -0.376 | -0.5823 | Yes | ||
183 | WDR37 | 2630519 6840347 | 17244 | -0.430 | -0.5846 | Yes | ||
184 | NFYA | 5860368 | 17275 | -0.443 | -0.5810 | Yes | ||
185 | MKRN1 | 1410097 | 17317 | -0.463 | -0.5778 | Yes | ||
186 | ASF1B | 6590706 | 17360 | -0.486 | -0.5744 | Yes | ||
187 | HIC2 | 4010433 | 17372 | -0.492 | -0.5692 | Yes | ||
188 | MAP3K14 | 5890435 | 17378 | -0.493 | -0.5637 | Yes | ||
189 | MTMR3 | 1050014 4920180 | 17457 | -0.526 | -0.5617 | Yes | ||
190 | TMEM16F | 5860008 | 17501 | -0.544 | -0.5577 | Yes | ||
191 | HN1 | 3360156 | 17535 | -0.560 | -0.5529 | Yes | ||
192 | SPOP | 450035 | 17567 | -0.575 | -0.5478 | Yes | ||
193 | ZDHHC9 | 3940204 | 17575 | -0.577 | -0.5414 | Yes | ||
194 | RRAGD | 670075 | 17623 | -0.601 | -0.5369 | Yes | ||
195 | ULK1 | 6100315 | 17644 | -0.613 | -0.5307 | Yes | ||
196 | DUSP2 | 2370184 | 17677 | -0.631 | -0.5251 | Yes | ||
197 | MAP3K11 | 7000039 | 17763 | -0.692 | -0.5215 | Yes | ||
198 | FEM1C | 60300 6130717 6980164 | 17881 | -0.772 | -0.5188 | Yes | ||
199 | FOXJ2 | 2450441 | 17909 | -0.793 | -0.5110 | Yes | ||
200 | RUNX1 | 3840711 | 17925 | -0.807 | -0.5023 | Yes | ||
201 | BCL2L11 | 780044 4200601 | 17932 | -0.811 | -0.4931 | Yes | ||
202 | CREBL1 | 1340546 | 17943 | -0.823 | -0.4840 | Yes | ||
203 | TOB2 | 1240465 | 17985 | -0.853 | -0.4762 | Yes | ||
204 | ZFYVE26 | 6860152 | 18008 | -0.888 | -0.4669 | Yes | ||
205 | IRF2 | 5390044 | 18019 | -0.899 | -0.4569 | Yes | ||
206 | WDR45 | 1660538 | 18023 | -0.907 | -0.4464 | Yes | ||
207 | IHPK1 | 1340053 | 18031 | -0.918 | -0.4360 | Yes | ||
208 | KLF13 | 4670563 | 18239 | -1.228 | -0.4328 | Yes | ||
209 | PPP6C | 2450670 | 18244 | -1.236 | -0.4185 | Yes | ||
210 | PLAGL2 | 1770148 | 18310 | -1.390 | -0.4057 | Yes | ||
211 | MAML1 | 2760008 | 18333 | -1.456 | -0.3898 | Yes | ||
212 | MCL1 | 1660672 | 18366 | -1.559 | -0.3732 | Yes | ||
213 | ARHGEF18 | 2120279 | 18406 | -1.735 | -0.3549 | Yes | ||
214 | MAPK9 | 2060273 3780209 4070397 | 18415 | -1.759 | -0.3347 | Yes | ||
215 | PHF2 | 4060300 | 18416 | -1.760 | -0.3140 | Yes | ||
216 | RASSF2 | 2480079 5720546 | 18506 | -2.342 | -0.2913 | Yes | ||
217 | CCND2 | 5340167 | 18548 | -2.713 | -0.2616 | Yes | ||
218 | TLE4 | 1450064 1500519 | 18549 | -2.720 | -0.2296 | Yes | ||
219 | TOX | 3440053 | 18571 | -3.029 | -0.1952 | Yes | ||
220 | PLEKHM1 | 1050161 1990750 | 18573 | -3.050 | -0.1594 | Yes | ||
221 | BCL6 | 940100 | 18581 | -3.177 | -0.1224 | Yes | ||
222 | BTG1 | 4200735 6040131 6200133 | 18610 | -4.873 | -0.0666 | Yes | ||
223 | HRBL | 1850102 3830253 4780176 | 18613 | -5.691 | 0.0002 | Yes |