Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | REACTOME_TCR_SIGNALING |
| Enrichment Score (ES) | -0.78429765 |
| Normalized Enrichment Score (NES) | -1.5805345 |
| Nominal p-value | 0.011415525 |
| FDR q-value | 0.15483487 |
| FWER p-Value | 0.704 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTPRC | 130402 5290148 | 1795 | 0.364 | -0.0692 | No | ||
| 2 | NFKB1 | 5420358 | 2339 | 0.229 | -0.0813 | No | ||
| 3 | MAP3K7 | 6040068 | 2712 | 0.164 | -0.0890 | No | ||
| 4 | ZAP70 | 1410494 2260504 | 3498 | 0.085 | -0.1249 | No | ||
| 5 | UBE2N | 520369 2900047 | 4590 | 0.036 | -0.1809 | No | ||
| 6 | ENAH | 1690292 5700300 | 4595 | 0.035 | -0.1785 | No | ||
| 7 | RIPK2 | 5050072 6290632 | 5362 | 0.023 | -0.2180 | No | ||
| 8 | GRAP2 | 7100441 1410647 | 6397 | 0.013 | -0.2726 | No | ||
| 9 | PIK3R1 | 4730671 | 7181 | 0.009 | -0.3141 | No | ||
| 10 | PRKCQ | 2260170 3870193 | 9203 | 0.001 | -0.4227 | No | ||
| 11 | NCK1 | 6200575 6510050 | 9651 | 0.000 | -0.4468 | No | ||
| 12 | CHUK | 7050736 | 12475 | -0.010 | -0.5979 | No | ||
| 13 | PLCG1 | 6020369 | 12813 | -0.012 | -0.6151 | No | ||
| 14 | PAK1 | 4540315 | 13205 | -0.015 | -0.6350 | No | ||
| 15 | IKBKB | 6840072 | 15396 | -0.080 | -0.7469 | No | ||
| 16 | LCP2 | 2680066 6650707 | 16038 | -0.152 | -0.7700 | Yes | ||
| 17 | WAS | 5270193 | 16305 | -0.192 | -0.7699 | Yes | ||
| 18 | CSK | 6350593 | 16371 | -0.204 | -0.7581 | Yes | ||
| 19 | PIK3CB | 3800600 | 16391 | -0.208 | -0.7435 | Yes | ||
| 20 | LAT | 3170025 | 16412 | -0.213 | -0.7286 | Yes | ||
| 21 | FYB | 1690440 | 16867 | -0.305 | -0.7301 | Yes | ||
| 22 | RELA | 3830075 | 16981 | -0.335 | -0.7111 | Yes | ||
| 23 | PTEN | 3390064 | 17072 | -0.362 | -0.6887 | Yes | ||
| 24 | LCK | 3360142 | 17374 | -0.493 | -0.6680 | Yes | ||
| 25 | CD3D | 2810739 | 17668 | -0.628 | -0.6366 | Yes | ||
| 26 | BCL10 | 2360397 | 17750 | -0.680 | -0.5899 | Yes | ||
| 27 | NFKBIA | 1570152 | 17914 | -0.797 | -0.5389 | Yes | ||
| 28 | CD4 | 1090010 | 17959 | -0.836 | -0.4785 | Yes | ||
| 29 | CD3E | 3800056 | 18183 | -1.120 | -0.4065 | Yes | ||
| 30 | PDPK1 | 6650168 | 18363 | -1.543 | -0.3004 | Yes | ||
| 31 | CD3G | 2680288 | 18446 | -1.891 | -0.1630 | Yes | ||
| 32 | ITK | 2230592 | 18500 | -2.294 | 0.0062 | Yes |
