Details for gene set REACTOME_SIGNALING_BY

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	REACTOME_SIGNALING_BY_GPCR
Enrichment Score (ES)	-0.6952698
Normalized Enrichment Score (NES)	-1.7397975
Nominal p-value	0.0
FDR q-value	0.02165961
FWER p-Value	0.019

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	F2	5720280	120	2.310	0.0637	No
2	CNR2	2760398	1025	0.669	0.0351	No
3	GAL	3930279	1267	0.552	0.0388	No
4	P2RY6	5290400	2062	0.293	0.0047	No
5	P2RY10	6370039 6840204	2604	0.179	-0.0191	No
6	ROCK1	130044	2627	0.176	-0.0150	No
7	P2RY2	2640180 2810128	2908	0.138	-0.0259	No
8	GPR17	5890671	2917	0.137	-0.0222	No
9	CCL25	450541 540435	3226	0.109	-0.0356	No
10	ADCY6	450364 6290670 6940286	3240	0.107	-0.0330	No
11	HRH2	3840440	3242	0.107	-0.0298	No
12	SCTR	2940070	3641	0.075	-0.0491	No
13	LTB4R	1770056	3871	0.061	-0.0596	No
14	PDE4D	2470528 6660014	3914	0.059	-0.0601	No
15	NTSR1	6510136	3984	0.055	-0.0622	No
16	PDYN	5720408	3995	0.055	-0.0611	No
17	PNOC	1990114	4226	0.045	-0.0721	No
18	OPN1SW	6420377	4632	0.035	-0.0930	No
19	AVP	2100113	4766	0.032	-0.0992	No
20	GRK5	1940348 4670053	4939	0.029	-0.1077	No
21	AVPR1A	2120300	4965	0.028	-0.1082	No
22	ADCYAP1	520086	5025	0.027	-0.1106	No
23	GCG	6220735	5145	0.025	-0.1162	No
24	ADRA1D	380035 540025	5268	0.024	-0.1221	No
25	PTGER2	3170039	5317	0.023	-0.1240	No
26	PLCB2	360132	5394	0.022	-0.1274	No
27	IAPP	4230040	5437	0.022	-0.1290	No
28	GNA14	3390017	5530	0.021	-0.1334	No
29	SSTR1	2630471	5654	0.019	-0.1395	No
30	KISS1	1580398	5854	0.017	-0.1497	No
31	GALR1	6020452	6040	0.016	-0.1592	No
32	MC2R	2970504	6058	0.016	-0.1597	No
33	PTGER3	2900739 6770750	6115	0.015	-0.1622	No
34	CGB	580273	6268	0.014	-0.1700	No
35	NTS	380300 2120592	6294	0.014	-0.1710	No
36	IL8RB	450592 1170537	6380	0.013	-0.1752	No
37	CASR	610504	6413	0.013	-0.1765	No
38	TSHR	1190687 5270364	6445	0.013	-0.1778	No
39	CCK	6370368	6940	0.010	-0.2042	No
40	CCR3	50427	6950	0.010	-0.2044	No
41	CXCL11	1090551	6964	0.010	-0.2048	No
42	HCRTR2	2350463	7160	0.009	-0.2151	No
43	PIK3R1	4730671	7181	0.009	-0.2159	No
44	TACR3	4780017	7184	0.009	-0.2157	No
45	MTNR1A	380204	7321	0.008	-0.2228	No
46	TACR2	1740358	7324	0.008	-0.2227	No
47	HTR1F	670148	7334	0.008	-0.2229	No
48	LHCGR	4560465 5860551	7394	0.008	-0.2259	No
49	DRD1	430025	7424	0.008	-0.2272	No
50	VIP	2850647	7484	0.008	-0.2302	No
51	PPY	2340373	7573	0.007	-0.2347	No
52	GLP2R	4150577 5290273 7050095	7590	0.007	-0.2354	No
53	AKT1	5290746	7820	0.006	-0.2476	No
54	SST	6590142	8056	0.005	-0.2601	No
55	HCRT	2970463	8070	0.005	-0.2607	No
56	ADM2	4060102	8082	0.005	-0.2611	No
57	CCKBR	2760128	8170	0.005	-0.2657	No
58	C5AR1	4540402	8239	0.005	-0.2692	No
59	GLP1R	6420528	8327	0.004	-0.2738	No
60	EDNRA	6900133	8329	0.004	-0.2737	No
61	GNAT1	5270048 6100170	8387	0.004	-0.2766	No
62	GRPR	6020170	8433	0.004	-0.2790	No
63	ADRA2A	5340520	8449	0.004	-0.2797	No
64	PPYR1	1410072	8555	0.004	-0.2852	No
65	VIPR2	6520050	8636	0.003	-0.2895	No
66	GNAZ	6130296	8663	0.003	-0.2908	No
67	GPRC6A	4560576	8765	0.003	-0.2961	No
68	GHRHR	3130500 4010154	8915	0.002	-0.3041	No
69	PTGER1	6100132	9087	0.002	-0.3133	No
70	PTGFR	3850373	9148	0.002	-0.3165	No
71	OXT	3850692	9270	0.001	-0.3230	No
72	GHRH	4570575	9363	0.001	-0.3280	No
73	BAI3	940692	9500	0.001	-0.3353	No
74	ADORA1	6370520	9664	0.000	-0.3442	No
75	GIP	3170364	9670	0.000	-0.3444	No
76	EDN1	1770047	9775	-0.000	-0.3500	No
77	PIK3CA	6220129	9883	-0.001	-0.3558	No
78	ADCYAP1R1	3390020 4280184 5360180	10113	-0.001	-0.3682	No
79	HTR6	4850022	10202	-0.002	-0.3729	No
80	P2RY4	630053	10522	-0.002	-0.3901	No
81	CRH	3710301	10535	-0.003	-0.3907	No
82	HRH1	840100	10572	-0.003	-0.3925	No
83	CALCA	5860167	10672	-0.003	-0.3978	No
84	CCR10	4050097	10815	-0.003	-0.4054	No
85	GNGT1	5220156	11085	-0.004	-0.4198	No
86	DARC	3940050	11155	-0.005	-0.4234	No
87	TACR1	70358 3840411	11250	-0.005	-0.4283	No
88	IL8RA	1580100	11340	-0.005	-0.4330	No
89	CHRM5	5390333	11386	-0.005	-0.4353	No
90	CHRM2	870750	11393	-0.005	-0.4354	No
91	KNG1	6400576 6770347	11470	-0.006	-0.4394	No
92	DRD3	4780402	11570	-0.006	-0.4445	No
93	TAC1	7000195 380706	11607	-0.006	-0.4463	No
94	GCGR	6620497	11619	-0.006	-0.4467	No
95	LHB	1450368	11632	-0.006	-0.4472	No
96	HCRTR1	1580273	11664	-0.006	-0.4486	No
97	AGTR1	4780524 2680592	11668	-0.006	-0.4486	No
98	CALCR	1690494	12280	-0.009	-0.4814	No
99	FSHR	610041 7040121	12307	-0.009	-0.4825	No
100	CGA	630403	12431	-0.010	-0.4889	No
101	CXCR6	3190440	12450	-0.010	-0.4896	No
102	TSHB	6770500	12745	-0.012	-0.5051	No
103	XCR1	5080072	12826	-0.012	-0.5091	No
104	PTGDR	3850161	13087	-0.014	-0.5227	No
105	FSHB	7100592	13219	-0.015	-0.5293	No
106	AGT	7000575	13238	-0.016	-0.5298	No
107	MC5R	2640176	13500	-0.018	-0.5434	No
108	NPFF	2030280	13546	-0.018	-0.5453	No
109	BDKRB1	730592	13903	-0.024	-0.5638	No
110	OPRM1	5360279	13936	-0.024	-0.5648	No
111	P2RY1	6040121	14107	-0.027	-0.5732	No
112	CRHR2	4590672	14113	-0.027	-0.5727	No
113	ADORA2A	1990687	14116	-0.027	-0.5719	No
114	CALCRL	4280035	14331	-0.032	-0.5826	No
115	CCR6	5720368 6020176	14337	-0.032	-0.5819	No
116	GRM6	2030398	14350	-0.032	-0.5815	No
117	CX3CL1	3990707	14503	-0.035	-0.5887	No
118	GNAQ	430670 4210131 5900736	14645	-0.040	-0.5951	No
119	AVPR2	360064	14915	-0.051	-0.6081	No
120	GNA12	1230301	15101	-0.060	-0.6163	No
121	HTR2A	360037 6330255	15199	-0.067	-0.6196	No
122	SCT	2230348	15392	-0.079	-0.6275	No
123	P2RY14	6100497	16077	-0.158	-0.6598	No
124	GNA13	4590102	16639	-0.254	-0.6824	Yes
125	NMB	3360735	16697	-0.265	-0.6774	Yes
126	ADRBK1	1340333	16790	-0.283	-0.6738	Yes
127	PTGIR	2100563	16902	-0.313	-0.6703	Yes
128	RHOG	6760575	17364	-0.489	-0.6804	Yes
129	RAMP1	2320168	17482	-0.534	-0.6705	Yes
130	GNG2	2230390	17510	-0.549	-0.6553	Yes
131	PIK3CG	5890110	17542	-0.565	-0.6398	Yes
132	GNB1	2120397	17751	-0.681	-0.6304	Yes
133	ADRB2	3290373	17896	-0.784	-0.6144	Yes
134	F2R	4810180	18172	-1.096	-0.5960	Yes
135	PDPK1	6650168	18363	-1.543	-0.5594	Yes
136	GNAS	630441 1850373 4050152	18468	-2.029	-0.5034	Yes
137	TBXA2R	2370292 3940066	18517	-2.443	-0.4318	Yes
138	CCL5	3710397	18554	-2.751	-0.3502	Yes
139	XCL1	3800504	18560	-2.844	-0.2641	Yes
140	CCR7	2060687	18568	-3.010	-0.1731	Yes
141	RHOA	580142 5900131 5340450	18614	-5.784	0.0001	Yes