Details for gene set REACTOME_GLUCOSE_REGULATION_OF_INSULIN

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	wtNotch
GeneSet	REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION
Enrichment Score (ES)	0.66875064
Normalized Enrichment Score (NES)	1.5353504
Nominal p-value	0.006993007
FDR q-value	0.11947939
FWER p-Value	0.911

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PGK1	1570494 630300	8	5.004	0.1300	Yes
2	PKM2	6520403 70500	34	3.793	0.2276	Yes
3	TPI1	1500215 2100154	44	3.470	0.3176	Yes
4	CYC1	2850546	498	1.122	0.3224	Yes
5	IDH3A	460332	517	1.096	0.3500	Yes
6	ATP5G1	5290019	729	0.902	0.3621	Yes
7	NDUFS3	1690136 5340528	777	0.874	0.3824	Yes
8	CYCS	2030072	807	0.851	0.4030	Yes
9	ETFB	2690025	811	0.850	0.4250	Yes
10	NDUFA10	5570347	834	0.826	0.4454	Yes
11	NDUFB8	2260450	921	0.750	0.4603	Yes
12	COX5A	1450609	962	0.711	0.4767	Yes
13	UQCRC1	520053	1040	0.664	0.4898	Yes
14	MDH2	1850601	1135	0.607	0.5006	Yes
15	NDUFV1	5420369	1337	0.522	0.5034	Yes
16	ATP5C1	5910601	1342	0.520	0.5167	Yes
17	DLST	2320722	1488	0.461	0.5209	Yes
18	ETFA	50347 5690040 6370044	1537	0.441	0.5298	Yes
19	NDUFA8	3460491	1647	0.409	0.5346	Yes
20	PDHA1	5550397	1693	0.392	0.5424	Yes
21	ATP5E	4120411	1699	0.391	0.5523	Yes
22	NDUFA6	3990348	1706	0.389	0.5621	Yes
23	UQCR	6130025	1712	0.386	0.5719	Yes
24	UQCRB	1450047	1767	0.372	0.5787	Yes
25	NDUFB5	110685	1793	0.364	0.5869	Yes
26	SDHD	2570128	1822	0.357	0.5946	Yes
27	NDUFB7	1850026	1882	0.340	0.6003	Yes
28	NDUFS7	1740142	1929	0.327	0.6064	Yes
29	NDUFB10	5900576	1978	0.314	0.6120	Yes
30	ATP5D	6550167	2044	0.298	0.6162	Yes
31	NDUFS2	4850020 6200402	2059	0.293	0.6231	Yes
32	IDH3B	5690070	2168	0.268	0.6243	Yes
33	ATP5A1	1990722	2195	0.262	0.6297	Yes
34	COX5B	6550670	2292	0.238	0.6307	Yes
35	PFKFB2	3940538 7100059	2307	0.235	0.6361	Yes
36	ATP5O	7000398	2311	0.234	0.6420	Yes
37	CS	5080600	2436	0.210	0.6408	Yes
38	ETFDH	4670358	2451	0.206	0.6454	Yes
39	NDUFS8	4150100	2467	0.204	0.6499	Yes
40	DLAT	430452	2471	0.202	0.6550	Yes
41	SDHB	3120398 4780113 3710435	2612	0.178	0.6521	Yes
42	DLD	4150403 6590341	2678	0.169	0.6530	Yes
43	COX8A	3780500	2690	0.167	0.6568	Yes
44	ATP5I	6220047	2695	0.166	0.6609	Yes
45	ATP5F1	7000725	2733	0.161	0.6631	Yes
46	NDUFB2	1230750	2819	0.150	0.6624	Yes
47	COX6C	1400020	2842	0.146	0.6650	Yes
48	NDUFA1	6200411	2895	0.139	0.6659	Yes
49	NDUFC2	580075	2909	0.138	0.6688	Yes
50	NDUFA9	2260280	3156	0.115	0.6585	No
51	COX7B	2340504	3213	0.110	0.6583	No
52	UQCRC2	5550091	3452	0.089	0.6478	No
53	NDUFA11	3780333	3489	0.086	0.6481	No
54	NDUFAB1	1980091	3623	0.076	0.6429	No
55	SLC2A2	5130537 5720722 6770079	3873	0.061	0.6311	No
56	IDH3G	6860706	3908	0.059	0.6308	No
57	NDUFA7	5900722	4054	0.052	0.6243	No
58	NDUFA5	5720239 6550035	4536	0.037	0.5993	No
59	NDUFB4	460348 5690594	5271	0.024	0.5603	No
60	NDUFS5	4010692	5345	0.023	0.5569	No
61	PDHX	870315	5988	0.016	0.5227	No
62	UQCRFS1	6620576	6896	0.010	0.4740	No
63	KCNJ11	2510131	6999	0.010	0.4688	No
64	ATP5J	4210100 6900288	7398	0.008	0.4475	No
65	SUCLG1	1850082 5290270	7985	0.006	0.4160	No
66	ATP5J2	2630706	8801	0.003	0.3721	No
67	SDHA	7000056	10242	-0.002	0.2944	No
68	PFKFB1	2370128	12179	-0.009	0.1902	No
69	NDUFS1	2650253	12667	-0.011	0.1642	No
70	ABCC8	2810671 3120671	12878	-0.013	0.1532	No
71	SYT5	4150082	13411	-0.017	0.1249	No
72	COX6B1	3710440 6180438	13488	-0.018	0.1213	No
73	COX7C	2470047	14891	-0.050	0.0469	No
74	OGDH	3840333 6350100	14904	-0.050	0.0476	No
75	COX4I1	5340427	15177	-0.065	0.0346	No
76	ATP5H	670438	15249	-0.070	0.0326	No
77	VAMP2	2100100	15502	-0.091	0.0213	No
78	COX6A1	1050095 1450239	15532	-0.093	0.0222	No
79	ATP5B	3870138	15922	-0.137	0.0048	No
80	NDUFB3	4610687	16363	-0.203	-0.0137	No
81	PFKFB3	630706	16409	-0.212	-0.0106	No
82	PDHB	70215 610086	16745	-0.273	-0.0215	No
83	UQCRH	4210463	17017	-0.345	-0.0272	No
84	NDUFA4	6860364	17112	-0.377	-0.0224	No
85	NDUFA2	6020100	17153	-0.393	-0.0143	No
86	NDUFA3	6040438	17599	-0.587	-0.0230	No
87	PRKACB	4210170	17608	-0.594	-0.0080	No
88	NDUFS4	510142 1240148 4760253	17739	-0.668	0.0024	No
89	COX7A2L	1500142	17880	-0.771	0.0150	No
90	NDUFC1	2570377 4200239	18059	-0.947	0.0301	No