Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | REACTOME_GENE_EXPRESSION |
Enrichment Score (ES) | 0.6520575 |
Normalized Enrichment Score (NES) | 1.5699731 |
Nominal p-value | 0.0 |
FDR q-value | 0.081080064 |
FWER p-Value | 0.676 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL38 | 70040 4060138 6200601 | 2 | 8.396 | 0.1351 | Yes | ||
2 | SMC1A | 3060600 5700148 5890113 6370154 | 134 | 2.203 | 0.1635 | Yes | ||
3 | EIF2S2 | 770095 2810487 | 137 | 2.172 | 0.1984 | Yes | ||
4 | SNRPA1 | 1050735 6110131 | 177 | 1.916 | 0.2271 | Yes | ||
5 | AARS | 1570279 2370136 | 187 | 1.874 | 0.2568 | Yes | ||
6 | METTL3 | 360497 | 221 | 1.775 | 0.2836 | Yes | ||
7 | TXNL4A | 4120286 6510242 | 339 | 1.428 | 0.3002 | Yes | ||
8 | CCAR1 | 3190092 | 388 | 1.319 | 0.3189 | Yes | ||
9 | U2AF1 | 5130292 | 407 | 1.287 | 0.3386 | Yes | ||
10 | RPS24 | 5420377 | 453 | 1.188 | 0.3553 | Yes | ||
11 | ETF1 | 6770075 | 456 | 1.182 | 0.3743 | Yes | ||
12 | POLR2E | 2900348 3360348 | 507 | 1.107 | 0.3894 | Yes | ||
13 | CCNH | 3190347 | 562 | 1.041 | 0.4032 | Yes | ||
14 | RPS3A | 2470086 | 610 | 0.998 | 0.4167 | Yes | ||
15 | NARS | 1660722 | 652 | 0.957 | 0.4299 | Yes | ||
16 | RPS19 | 5860066 | 672 | 0.943 | 0.4441 | Yes | ||
17 | RARS | 380390 | 675 | 0.941 | 0.4591 | Yes | ||
18 | SFRS6 | 60224 | 699 | 0.926 | 0.4728 | Yes | ||
19 | EIF4A1 | 1990341 2810300 | 806 | 0.852 | 0.4808 | Yes | ||
20 | TCEB1 | 1170619 | 808 | 0.850 | 0.4944 | Yes | ||
21 | GARS | 1230601 | 845 | 0.818 | 0.5057 | Yes | ||
22 | GTF2H1 | 2570746 2650148 | 855 | 0.811 | 0.5182 | Yes | ||
23 | NUP93 | 2190273 | 876 | 0.795 | 0.5300 | Yes | ||
24 | YBX1 | 1340039 4730500 | 980 | 0.695 | 0.5356 | Yes | ||
25 | TBP | 1450601 2810193 | 1004 | 0.681 | 0.5453 | Yes | ||
26 | GTF2H2 | 5130358 | 1054 | 0.654 | 0.5532 | Yes | ||
27 | PHF5A | 2690519 | 1061 | 0.649 | 0.5633 | Yes | ||
28 | CPSF1 | 6290064 | 1066 | 0.647 | 0.5735 | Yes | ||
29 | EIF2B2 | 4290048 | 1096 | 0.629 | 0.5821 | Yes | ||
30 | EIF2B1 | 4610082 7040242 | 1245 | 0.560 | 0.5831 | Yes | ||
31 | CCNC | 3390750 | 1257 | 0.556 | 0.5914 | Yes | ||
32 | SNRPF | 3170280 | 1265 | 0.553 | 0.5999 | Yes | ||
33 | EIF4B | 5390563 5270577 | 1274 | 0.548 | 0.6083 | Yes | ||
34 | POLR2I | 4060400 | 1307 | 0.535 | 0.6152 | Yes | ||
35 | SFRS9 | 3800047 | 1340 | 0.522 | 0.6219 | Yes | ||
36 | NUP160 | 1990551 | 1529 | 0.444 | 0.6189 | Yes | ||
37 | SF3A3 | 6660603 | 1532 | 0.442 | 0.6259 | Yes | ||
38 | NUP43 | 3360482 | 1589 | 0.430 | 0.6298 | Yes | ||
39 | RAE1 | 7050121 | 1786 | 0.368 | 0.6251 | Yes | ||
40 | GTF2E2 | 4010441 | 1809 | 0.360 | 0.6297 | Yes | ||
41 | SF3A2 | 3140500 | 1839 | 0.352 | 0.6338 | Yes | ||
42 | SFRS2 | 50707 380593 | 1912 | 0.330 | 0.6352 | Yes | ||
43 | RNMT | 1770500 | 1954 | 0.321 | 0.6381 | Yes | ||
44 | NUPL2 | 6550537 | 1976 | 0.315 | 0.6421 | Yes | ||
45 | SFRS3 | 770315 4230593 | 2053 | 0.295 | 0.6427 | Yes | ||
46 | EIF4G1 | 4070446 | 2065 | 0.292 | 0.6468 | Yes | ||
47 | RPS23 | 7100594 | 2146 | 0.272 | 0.6469 | Yes | ||
48 | RPS15A | 1170180 | 2172 | 0.268 | 0.6498 | Yes | ||
49 | RPL14 | 5080471 | 2209 | 0.259 | 0.6521 | Yes | ||
50 | YARS | 70739 | 2440 | 0.209 | 0.6430 | No | ||
51 | POLR2H | 5890242 | 2477 | 0.201 | 0.6443 | No | ||
52 | CSTF1 | 4610129 | 2482 | 0.201 | 0.6473 | No | ||
53 | SNRPD2 | 6110035 | 2551 | 0.189 | 0.6466 | No | ||
54 | EEF1G | 3940603 | 2597 | 0.180 | 0.6471 | No | ||
55 | RPL5 | 840095 | 2647 | 0.173 | 0.6472 | No | ||
56 | SF3B3 | 3710044 | 2763 | 0.157 | 0.6435 | No | ||
57 | RPS2 | 1340647 | 2866 | 0.144 | 0.6403 | No | ||
58 | SNRPB | 1230097 2940086 3520671 | 2899 | 0.139 | 0.6408 | No | ||
59 | PTBP1 | 4070736 | 2959 | 0.133 | 0.6398 | No | ||
60 | POLR2A | 5220647 | 3173 | 0.114 | 0.6301 | No | ||
61 | RPL37A | 7040717 | 3221 | 0.110 | 0.6293 | No | ||
62 | RPL4 | 2940014 5420324 | 3322 | 0.099 | 0.6255 | No | ||
63 | RPL18A | 4570619 | 3327 | 0.099 | 0.6269 | No | ||
64 | RPS13 | 1570364 | 3408 | 0.092 | 0.6240 | No | ||
65 | GTF2H3 | 50600 | 3455 | 0.089 | 0.6230 | No | ||
66 | SF3B4 | 110072 | 3537 | 0.082 | 0.6199 | No | ||
67 | POLR2J | 7100372 | 3620 | 0.076 | 0.6167 | No | ||
68 | NUP54 | 940546 2360156 4060278 | 3718 | 0.069 | 0.6126 | No | ||
69 | RANBP2 | 4280338 | 3789 | 0.065 | 0.6098 | No | ||
70 | RPL27A | 3130451 110195 6840494 | 3837 | 0.062 | 0.6083 | No | ||
71 | FARS2 | 5340575 | 3863 | 0.061 | 0.6079 | No | ||
72 | NUP62 | 1240128 | 4272 | 0.044 | 0.5865 | No | ||
73 | EIF2S1 | 5360292 | 4459 | 0.039 | 0.5771 | No | ||
74 | TH1L | 1190632 | 5490 | 0.021 | 0.5216 | No | ||
75 | SNW1 | 4010736 | 5625 | 0.020 | 0.5147 | No | ||
76 | POLR2C | 1690020 | 5741 | 0.019 | 0.5088 | No | ||
77 | CCNT2 | 2100390 4150563 | 6133 | 0.015 | 0.4879 | No | ||
78 | EPRS | 3170301 | 6167 | 0.015 | 0.4863 | No | ||
79 | SF3B1 | 7000632 | 6492 | 0.013 | 0.4690 | No | ||
80 | GTF2A2 | 2230184 | 7512 | 0.008 | 0.4139 | No | ||
81 | RPL41 | 6940112 | 7654 | 0.007 | 0.4064 | No | ||
82 | RPL17 | 2690167 5690504 | 7848 | 0.006 | 0.3961 | No | ||
83 | CDK7 | 2640451 | 8024 | 0.006 | 0.3867 | No | ||
84 | TAF4 | 1450170 | 9006 | 0.002 | 0.3336 | No | ||
85 | NUP153 | 7000452 | 9036 | 0.002 | 0.3321 | No | ||
86 | TAF9 | 1850458 3830136 | 9836 | -0.000 | 0.2888 | No | ||
87 | HARS | 6100487 | 9967 | -0.001 | 0.2818 | No | ||
88 | NFX1 | 450504 | 10516 | -0.002 | 0.2522 | No | ||
89 | RNPS1 | 610736 1090021 | 10730 | -0.003 | 0.2407 | No | ||
90 | RBM5 | 3520402 5270121 | 10792 | -0.003 | 0.2374 | No | ||
91 | TAF11 | 5720538 | 10849 | -0.004 | 0.2345 | No | ||
92 | NUP35 | 5340408 | 11131 | -0.004 | 0.2193 | No | ||
93 | EIF5B | 1190102 4200440 | 11189 | -0.005 | 0.2163 | No | ||
94 | ERCC3 | 6900008 | 11347 | -0.005 | 0.2079 | No | ||
95 | POLR2B | 3780138 | 11790 | -0.007 | 0.1841 | No | ||
96 | RNGTT | 780152 780746 1090471 | 11793 | -0.007 | 0.1841 | No | ||
97 | SNRPG | 2340551 | 11804 | -0.007 | 0.1837 | No | ||
98 | DHX9 | 60017 1170095 2260014 | 12113 | -0.008 | 0.1671 | No | ||
99 | TPR | 1990066 6550390 | 12150 | -0.009 | 0.1653 | No | ||
100 | SNRPB2 | 5720577 | 12663 | -0.011 | 0.1378 | No | ||
101 | TAF12 | 3710746 4920300 6180603 | 12755 | -0.012 | 0.1330 | No | ||
102 | LARS2 | 7000706 | 12761 | -0.012 | 0.1330 | No | ||
103 | RPS21 | 3120673 | 13028 | -0.014 | 0.1188 | No | ||
104 | EEF1E1 | 4540711 | 13040 | -0.014 | 0.1184 | No | ||
105 | RPL27 | 1940088 | 13264 | -0.016 | 0.1066 | No | ||
106 | IARS | 460528 1580739 1690008 | 13435 | -0.017 | 0.0977 | No | ||
107 | RPL18 | 6380181 3870195 | 13857 | -0.023 | 0.0752 | No | ||
108 | RPS28 | 3830221 | 13892 | -0.023 | 0.0738 | No | ||
109 | EEF2 | 1050369 4670035 5890598 | 13923 | -0.024 | 0.0725 | No | ||
110 | GTF2B | 6860685 | 14124 | -0.027 | 0.0622 | No | ||
111 | EIF5 | 6380750 | 14406 | -0.033 | 0.0475 | No | ||
112 | RPLP2 | 5290020 | 14574 | -0.038 | 0.0390 | No | ||
113 | RARS2 | 5570524 6290497 6900332 | 14600 | -0.038 | 0.0383 | No | ||
114 | RPS20 | 1740092 | 14729 | -0.043 | 0.0321 | No | ||
115 | RPL6 | 6040735 | 15133 | -0.062 | 0.0112 | No | ||
116 | RPS16 | 510722 | 15161 | -0.064 | 0.0108 | No | ||
117 | NUDT21 | 1240167 | 15229 | -0.068 | 0.0083 | No | ||
118 | RPS5 | 580093 | 15284 | -0.072 | 0.0065 | No | ||
119 | U2AF2 | 450600 4670128 5420292 | 15431 | -0.084 | -0.0000 | No | ||
120 | RPL8 | 20296 | 15620 | -0.102 | -0.0086 | No | ||
121 | RPLP1 | 3140292 | 15634 | -0.103 | -0.0076 | No | ||
122 | RPL28 | 6900136 | 15763 | -0.116 | -0.0127 | No | ||
123 | FAU | 7100465 | 15915 | -0.136 | -0.0186 | No | ||
124 | RDBP | 6590044 | 15959 | -0.142 | -0.0187 | No | ||
125 | RPS29 | 580324 | 16104 | -0.163 | -0.0239 | No | ||
126 | EIF4E | 1580403 70133 6380215 | 16200 | -0.177 | -0.0261 | No | ||
127 | RPL19 | 5550592 | 16277 | -0.188 | -0.0272 | No | ||
128 | MAGOH | 2370373 5050068 | 16361 | -0.203 | -0.0285 | No | ||
129 | PRPF8 | 1230497 1570600 | 16481 | -0.226 | -0.0313 | No | ||
130 | ELL | 3520731 | 16484 | -0.226 | -0.0277 | No | ||
131 | DNAJC8 | 4050075 | 16690 | -0.263 | -0.0346 | No | ||
132 | RPL11 | 3780435 | 16735 | -0.271 | -0.0326 | No | ||
133 | SFRS1 | 2360440 | 16829 | -0.295 | -0.0329 | No | ||
134 | SF3B2 | 6590576 | 16841 | -0.298 | -0.0287 | No | ||
135 | WARS | 2570717 3290139 | 17084 | -0.367 | -0.0359 | No | ||
136 | CD2BP2 | 1580301 | 17090 | -0.371 | -0.0302 | No | ||
137 | CCNT1 | 2450563 5390184 | 17237 | -0.428 | -0.0312 | No | ||
138 | MED6 | 6840500 | 17267 | -0.439 | -0.0257 | No | ||
139 | SFRS5 | 3450176 6350008 | 17328 | -0.468 | -0.0214 | No | ||
140 | PRPF4 | 430301 2970364 | 17440 | -0.519 | -0.0191 | No | ||
141 | TAF10 | 2760020 | 17506 | -0.548 | -0.0138 | No | ||
142 | SRRM1 | 6110025 | 17517 | -0.553 | -0.0054 | No | ||
143 | SFRS7 | 2760408 | 17758 | -0.687 | -0.0073 | No | ||
144 | SUPT4H1 | 6200056 | 17929 | -0.810 | -0.0035 | No | ||
145 | EIF4EBP1 | 60132 5720148 | 18525 | -2.523 | 0.0049 | No |