DatasetSet_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls
#wtNotch_versus_normalThy_repos
Phenotypephenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in classnormalThy
GeneSetREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
Enrichment Score (ES)-0.85232794
Normalized Enrichment Score (NES)-1.5849043
Nominal p-value0.008810572
FDR q-value0.1600569
FWER p-Value0.675
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CD8087011229700.133-0.1482No
2PDCD1412008237110.070-0.1819No
3GRAP27100441 141064763970.013-0.3251No
4PIK3R1473067171810.009-0.3665No
5AKT1529074678200.006-0.4002No
6PTPN112230100 2470180 610052891700.002-0.4727No
7PIK3CA62201299883-0.001-0.5109No
8PAK1454031513205-0.015-0.6882No
9ICOSLG7012814519-0.036-0.7557No
10CD863390471 620028015717-0.111-0.8104No
11MAP3K8294028616098-0.161-0.8168Yes
12FYN2100468 4760520 485068716182-0.174-0.8061Yes
13CSK635059316371-0.204-0.7984Yes
14LCK336014217374-0.493-0.8095Yes
15VAV1602048717649-0.615-0.7707Yes
16CD3D281073917668-0.628-0.7170Yes
17CD4109001017959-0.836-0.6598Yes
18CD3E380005618183-1.120-0.5744Yes
19PDPK1665016818363-1.543-0.4497Yes
20CTLA4659053718369-1.563-0.3139Yes
21CD281400739 421009318442-1.868-0.1553Yes
22CD3G268028818446-1.8910.0091Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY: Random ES distribution   
Gene set null distribution of ES for REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY