Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | NUCLEOPLASM |
Enrichment Score (ES) | -0.57001096 |
Normalized Enrichment Score (NES) | -1.5787143 |
Nominal p-value | 0.0 |
FDR q-value | 0.24189898 |
FWER p-Value | 0.971 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SFRS2 | 50707 380593 | 7 | 4.052 | 0.0721 | No | ||
2 | HES6 | 540411 6550504 | 96 | 1.504 | 0.0942 | No | ||
3 | HDAC5 | 2370035 6370139 | 355 | 0.797 | 0.0945 | No | ||
4 | TAF6 | 2470541 4280497 | 458 | 0.665 | 0.1008 | No | ||
5 | ERCC2 | 2360750 4060390 6550138 | 470 | 0.657 | 0.1120 | No | ||
6 | MCRS1 | 110121 2340592 5270484 | 732 | 0.496 | 0.1067 | No | ||
7 | SMARCB1 | 5860494 | 813 | 0.463 | 0.1106 | No | ||
8 | GEMIN7 | 2320433 | 821 | 0.460 | 0.1185 | No | ||
9 | TAF10 | 2760020 | 1067 | 0.380 | 0.1120 | No | ||
10 | HMGA1 | 6580408 | 1226 | 0.349 | 0.1096 | No | ||
11 | SMARCD1 | 3060193 3850184 6400369 | 1240 | 0.347 | 0.1151 | No | ||
12 | NUP98 | 2850465 | 1247 | 0.346 | 0.1210 | No | ||
13 | PMF1 | 5130273 | 1421 | 0.310 | 0.1172 | No | ||
14 | HTATIP | 5360739 | 1453 | 0.303 | 0.1209 | No | ||
15 | RBM14 | 5340731 5690315 | 1486 | 0.297 | 0.1245 | No | ||
16 | HDAC7A | 2570278 | 1494 | 0.296 | 0.1294 | No | ||
17 | EPC1 | 1570050 5290095 6900193 | 2078 | 0.205 | 0.1014 | No | ||
18 | MEN1 | 4850300 5900671 | 2092 | 0.203 | 0.1043 | No | ||
19 | RUVBL2 | 1190377 | 2141 | 0.197 | 0.1052 | No | ||
20 | ISG20 | 1770750 | 2214 | 0.188 | 0.1047 | No | ||
21 | HDAC6 | 6200446 | 2379 | 0.166 | 0.0988 | No | ||
22 | TOP1 | 770471 4060632 6650324 | 2420 | 0.162 | 0.0995 | No | ||
23 | HDAC3 | 4060072 | 2427 | 0.161 | 0.1020 | No | ||
24 | MPG | 2760021 | 2586 | 0.144 | 0.0960 | No | ||
25 | TAF6L | 1850056 | 2588 | 0.144 | 0.0986 | No | ||
26 | TIMM50 | 1500139 | 2595 | 0.143 | 0.1008 | No | ||
27 | ZBTB16 | 3290022 | 2803 | 0.123 | 0.0918 | No | ||
28 | APTX | 3360041 4560167 | 2823 | 0.121 | 0.0929 | No | ||
29 | NUDT21 | 1240167 | 2870 | 0.117 | 0.0925 | No | ||
30 | U2AF1 | 5130292 | 3081 | 0.102 | 0.0829 | No | ||
31 | TAF12 | 3710746 4920300 6180603 | 3221 | 0.092 | 0.0770 | No | ||
32 | EPAS1 | 5290156 | 3250 | 0.090 | 0.0771 | No | ||
33 | TAF9 | 1850458 3830136 | 3436 | 0.080 | 0.0685 | No | ||
34 | TFIP11 | 1340301 | 3445 | 0.079 | 0.0695 | No | ||
35 | CHEK2 | 610139 1050022 | 3468 | 0.079 | 0.0697 | No | ||
36 | NDUFA13 | 6220021 | 3475 | 0.078 | 0.0708 | No | ||
37 | TP53 | 6130707 | 3540 | 0.075 | 0.0686 | No | ||
38 | ACTB | 1660736 2030204 2060215 5050047 | 3579 | 0.073 | 0.0679 | No | ||
39 | HDAC10 | 2850204 | 3594 | 0.072 | 0.0684 | No | ||
40 | POLR2J | 7100372 | 3699 | 0.068 | 0.0640 | No | ||
41 | ATXN1 | 5550156 | 3707 | 0.068 | 0.0648 | No | ||
42 | CDK8 | 1050113 1190601 1780358 6110102 | 3747 | 0.066 | 0.0639 | No | ||
43 | CHAF1B | 3940142 | 3771 | 0.066 | 0.0638 | No | ||
44 | CIB1 | 7100722 | 3890 | 0.061 | 0.0585 | No | ||
45 | SMARCD3 | 4070497 | 3998 | 0.058 | 0.0537 | No | ||
46 | CHAF1A | 6040647 | 4123 | 0.054 | 0.0479 | No | ||
47 | INTS6 | 6040736 7570767 | 4392 | 0.046 | 0.0342 | No | ||
48 | NKX2-5 | 5390438 | 4396 | 0.046 | 0.0349 | No | ||
49 | LMO4 | 3800746 | 4468 | 0.045 | 0.0318 | No | ||
50 | TAF7 | 6400504 6660601 | 4636 | 0.040 | 0.0235 | No | ||
51 | FOXE3 | 6900102 | 4686 | 0.040 | 0.0215 | No | ||
52 | THRAP3 | 6180309 | 4835 | 0.037 | 0.0142 | No | ||
53 | WRN | 540687 1240093 | 4960 | 0.035 | 0.0080 | No | ||
54 | GCM1 | 6510687 | 5170 | 0.031 | -0.0027 | No | ||
55 | LRCH4 | 5220279 6510026 | 5192 | 0.031 | -0.0033 | No | ||
56 | OGG1 | 1940279 | 5739 | 0.024 | -0.0326 | No | ||
57 | RUVBL1 | 4280239 5080273 | 5754 | 0.023 | -0.0329 | No | ||
58 | POLR3C | 6940546 | 5819 | 0.023 | -0.0360 | No | ||
59 | HIPK2 | 6350647 | 5989 | 0.021 | -0.0448 | No | ||
60 | GLIS2 | 4150471 4810170 | 6309 | 0.018 | -0.0618 | No | ||
61 | NUFIP1 | 6350241 | 6390 | 0.017 | -0.0658 | No | ||
62 | NAP1L3 | 6020079 | 6496 | 0.016 | -0.0712 | No | ||
63 | POLR3K | 1400577 5290500 | 6625 | 0.016 | -0.0779 | No | ||
64 | PPP1R9B | 3130619 | 6884 | 0.014 | -0.0916 | No | ||
65 | CBX1 | 5080408 1980239 | 6946 | 0.013 | -0.0947 | No | ||
66 | SPTBN4 | 4150279 5270286 | 6979 | 0.013 | -0.0962 | No | ||
67 | IFI16 | 6520601 | 7254 | 0.012 | -0.1109 | No | ||
68 | FMR1 | 5050075 | 7468 | 0.011 | -0.1222 | No | ||
69 | SMARCD2 | 3830619 | 7662 | 0.010 | -0.1326 | No | ||
70 | NPAS2 | 770670 | 7804 | 0.009 | -0.1400 | No | ||
71 | POLR2B | 3780138 | 7960 | 0.009 | -0.1483 | No | ||
72 | PRM2 | 3060368 | 8100 | 0.008 | -0.1557 | No | ||
73 | FOXF2 | 1240091 | 8114 | 0.008 | -0.1563 | No | ||
74 | FIGLA | 4780458 | 8119 | 0.008 | -0.1563 | No | ||
75 | BNIP3 | 3140270 | 8305 | 0.007 | -0.1663 | No | ||
76 | POLR2A | 5220647 | 8436 | 0.007 | -0.1732 | No | ||
77 | HDAC9 | 1990010 2260133 | 8603 | 0.006 | -0.1821 | No | ||
78 | HIF1A | 5670605 | 8842 | 0.005 | -0.1949 | No | ||
79 | GEMIN6 | 2120288 3830176 | 9105 | 0.005 | -0.2091 | No | ||
80 | POLA1 | 4760541 | 9613 | 0.003 | -0.2365 | No | ||
81 | PHB | 2260739 | 9622 | 0.003 | -0.2369 | No | ||
82 | NCR1 | 2450026 | 10063 | 0.002 | -0.2608 | No | ||
83 | TAF5 | 3450288 5890193 6860435 | 10196 | 0.001 | -0.2679 | No | ||
84 | ELL2 | 6420091 | 10575 | 0.000 | -0.2884 | No | ||
85 | ELP4 | 1230576 | 10689 | 0.000 | -0.2946 | No | ||
86 | XPO1 | 540707 | 10862 | -0.000 | -0.3039 | No | ||
87 | SP100 | 3440632 | 11122 | -0.001 | -0.3179 | No | ||
88 | PITX2 | 870537 2690139 | 11222 | -0.001 | -0.3233 | No | ||
89 | TAF4 | 1450170 | 11457 | -0.002 | -0.3360 | No | ||
90 | NCOA6 | 1780333 6450110 | 11459 | -0.002 | -0.3360 | No | ||
91 | TDG | 2900358 2940079 | 11705 | -0.003 | -0.3492 | No | ||
92 | NAP1L2 | 130047 | 12094 | -0.004 | -0.3702 | No | ||
93 | CPSF3 | 2480671 | 12499 | -0.006 | -0.3920 | No | ||
94 | IKBKAP | 1740746 3120364 | 12698 | -0.007 | -0.4027 | No | ||
95 | UBE2I | 2680056 6350446 | 12940 | -0.008 | -0.4156 | No | ||
96 | NFYC | 1400746 | 12942 | -0.008 | -0.4155 | No | ||
97 | RTCD1 | 7000041 | 13040 | -0.009 | -0.4206 | No | ||
98 | PRPF31 | 6100360 | 13334 | -0.010 | -0.4364 | No | ||
99 | PTF1A | 6450377 | 13733 | -0.014 | -0.4577 | No | ||
100 | PAX8 | 5050301 5290164 | 13741 | -0.014 | -0.4579 | No | ||
101 | PML | 50093 2190435 2450402 3840082 | 13951 | -0.016 | -0.4689 | No | ||
102 | PPARGC1A | 4670040 | 13963 | -0.016 | -0.4692 | No | ||
103 | GEMIN5 | 3120577 | 14004 | -0.017 | -0.4711 | No | ||
104 | ATXN3 | 50156 2900095 | 14227 | -0.020 | -0.4828 | No | ||
105 | CLOCK | 1410070 2940292 3390075 | 14298 | -0.021 | -0.4862 | No | ||
106 | NR6A1 | 4010347 | 14357 | -0.022 | -0.4890 | No | ||
107 | PHF21A | 610014 | 14450 | -0.023 | -0.4936 | No | ||
108 | RELA | 3830075 | 14477 | -0.024 | -0.4946 | No | ||
109 | TOPBP1 | 6020333 | 14491 | -0.024 | -0.4948 | No | ||
110 | HDAC8 | 3440504 | 14532 | -0.025 | -0.4966 | No | ||
111 | ARID4A | 520156 1050707 | 14810 | -0.031 | -0.5111 | No | ||
112 | ERCC5 | 770025 4540692 | 14813 | -0.032 | -0.5106 | No | ||
113 | SAP18 | 3610092 | 15068 | -0.040 | -0.5237 | No | ||
114 | WDR4 | 610390 1850368 3800338 4780463 | 15144 | -0.043 | -0.5270 | No | ||
115 | HDAC11 | 2510242 | 15228 | -0.046 | -0.5307 | No | ||
116 | GTF2F1 | 360093 | 15334 | -0.051 | -0.5354 | No | ||
117 | PTBP1 | 4070736 | 15409 | -0.055 | -0.5385 | No | ||
118 | ELF4 | 4850193 | 15444 | -0.057 | -0.5393 | No | ||
119 | PHF12 | 870400 3130687 | 15495 | -0.060 | -0.5410 | No | ||
120 | RBBP5 | 2760735 6760164 | 15562 | -0.065 | -0.5434 | No | ||
121 | MDM2 | 3450053 5080138 | 15571 | -0.065 | -0.5427 | No | ||
122 | POLQ | 1050053 2190102 | 15615 | -0.067 | -0.5438 | No | ||
123 | SMARCA5 | 6620050 | 15678 | -0.072 | -0.5459 | No | ||
124 | DYRK1A | 3190181 | 15694 | -0.073 | -0.5454 | No | ||
125 | COIL | 4480408 | 15737 | -0.076 | -0.5463 | No | ||
126 | POLI | 4280215 | 15767 | -0.079 | -0.5465 | No | ||
127 | NARG1 | 5910563 6350095 | 15804 | -0.081 | -0.5470 | No | ||
128 | NUP54 | 940546 2360156 4060278 | 15832 | -0.084 | -0.5469 | No | ||
129 | POLR3H | 1980369 6400348 | 15900 | -0.088 | -0.5490 | No | ||
130 | GTF3C3 | 2450066 | 15959 | -0.093 | -0.5505 | No | ||
131 | ERCC3 | 6900008 | 15992 | -0.095 | -0.5505 | No | ||
132 | MCM7 | 3290292 5220056 | 16086 | -0.103 | -0.5537 | No | ||
133 | FUSIP1 | 520082 5390114 | 16103 | -0.105 | -0.5527 | No | ||
134 | TOP2B | 6980309 | 16219 | -0.116 | -0.5569 | No | ||
135 | CDK9 | 630707 | 16333 | -0.128 | -0.5607 | No | ||
136 | GTF3C5 | 4540280 4540309 | 16505 | -0.151 | -0.5673 | Yes | ||
137 | PPARGC1B | 3290114 | 16512 | -0.152 | -0.5649 | Yes | ||
138 | ASF1A | 7050020 | 16589 | -0.163 | -0.5661 | Yes | ||
139 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 16594 | -0.164 | -0.5634 | Yes | ||
140 | POLR2E | 2900348 3360348 | 16620 | -0.169 | -0.5618 | Yes | ||
141 | MYO6 | 2190332 | 16625 | -0.169 | -0.5589 | Yes | ||
142 | GTF2H4 | 3520100 | 16704 | -0.180 | -0.5600 | Yes | ||
143 | SHFM1 | 1570114 | 16705 | -0.180 | -0.5567 | Yes | ||
144 | SMARCE1 | 4920465 4390398 | 16743 | -0.186 | -0.5554 | Yes | ||
145 | MED6 | 6840500 | 16755 | -0.187 | -0.5527 | Yes | ||
146 | EZH2 | 6130605 6380524 | 16764 | -0.189 | -0.5497 | Yes | ||
147 | ARNTL | 3170463 | 16863 | -0.209 | -0.5513 | Yes | ||
148 | NFYA | 5860368 | 16987 | -0.229 | -0.5539 | Yes | ||
149 | TAF11 | 5720538 | 17002 | -0.232 | -0.5505 | Yes | ||
150 | CPSF1 | 6290064 | 17013 | -0.233 | -0.5469 | Yes | ||
151 | ING2 | 4850497 | 17027 | -0.237 | -0.5433 | Yes | ||
152 | HCLS1 | 7100309 | 17030 | -0.237 | -0.5392 | Yes | ||
153 | YEATS4 | 3130242 | 17042 | -0.240 | -0.5355 | Yes | ||
154 | HDAC1 | 2850670 | 17220 | -0.280 | -0.5401 | Yes | ||
155 | ASH2L | 580152 | 17269 | -0.295 | -0.5374 | Yes | ||
156 | SMAD2 | 4200592 | 17271 | -0.295 | -0.5322 | Yes | ||
157 | ZNF148 | 6420403 | 17296 | -0.302 | -0.5281 | Yes | ||
158 | TAF13 | 4050692 | 17339 | -0.316 | -0.5247 | Yes | ||
159 | GIT2 | 6040039 6770181 | 17367 | -0.323 | -0.5204 | Yes | ||
160 | OIP5 | 3120500 4780537 | 17375 | -0.324 | -0.5150 | Yes | ||
161 | GTF3C1 | 1990368 4210037 | 17444 | -0.342 | -0.5126 | Yes | ||
162 | MPHOSPH1 | 4610427 | 17479 | -0.351 | -0.5081 | Yes | ||
163 | NAP1L4 | 1240504 | 17495 | -0.354 | -0.5026 | Yes | ||
164 | MED4 | 4480050 | 17547 | -0.369 | -0.4988 | Yes | ||
165 | SNAPC4 | 2190184 | 17553 | -0.371 | -0.4924 | Yes | ||
166 | SMARCA4 | 6980528 | 17558 | -0.371 | -0.4860 | Yes | ||
167 | MKI67IP | 3060132 | 17577 | -0.379 | -0.4802 | Yes | ||
168 | GTF2H1 | 2570746 2650148 | 17587 | -0.381 | -0.4739 | Yes | ||
169 | RB1 | 5900338 | 17613 | -0.394 | -0.4682 | Yes | ||
170 | GTF3C2 | 670494 | 17641 | -0.406 | -0.4624 | Yes | ||
171 | POLH | 2690528 | 17651 | -0.409 | -0.4555 | Yes | ||
172 | RPA1 | 360452 | 17708 | -0.427 | -0.4509 | Yes | ||
173 | MED12 | 4920095 | 17715 | -0.430 | -0.4436 | Yes | ||
174 | GTF3C4 | 1940750 4730114 | 17717 | -0.432 | -0.4359 | Yes | ||
175 | RSF1 | 1580097 | 17746 | -0.443 | -0.4295 | Yes | ||
176 | RBM39 | 4230458 6450280 | 17786 | -0.458 | -0.4234 | Yes | ||
177 | ELP3 | 3440438 | 17802 | -0.467 | -0.4159 | Yes | ||
178 | MRE11A | 3850601 4670332 | 17933 | -0.523 | -0.4136 | Yes | ||
179 | TOPORS | 4060592 | 17954 | -0.535 | -0.4051 | Yes | ||
180 | KPNA2 | 3450114 | 17970 | -0.540 | -0.3962 | Yes | ||
181 | NFYB | 1850053 | 17987 | -0.548 | -0.3873 | Yes | ||
182 | WDHD1 | 3450390 | 17996 | -0.555 | -0.3778 | Yes | ||
183 | SAP30 | 5080735 | 18044 | -0.582 | -0.3699 | Yes | ||
184 | IVNS1ABP | 4760601 6520113 | 18081 | -0.605 | -0.3611 | Yes | ||
185 | TRIM27 | 3710575 4780112 | 18125 | -0.628 | -0.3522 | Yes | ||
186 | ZNF638 | 6510112 | 18145 | -0.641 | -0.3417 | Yes | ||
187 | SMAD4 | 5670519 | 18179 | -0.658 | -0.3318 | Yes | ||
188 | EED | 2320373 | 18198 | -0.671 | -0.3207 | Yes | ||
189 | SFRS2IP | 730687 1500373 | 18233 | -0.700 | -0.3100 | Yes | ||
190 | TOP2A | 360717 | 18276 | -0.748 | -0.2989 | Yes | ||
191 | SMARCC1 | 5080019 7100047 | 18369 | -0.848 | -0.2888 | Yes | ||
192 | TBP | 1450601 2810193 | 18389 | -0.872 | -0.2742 | Yes | ||
193 | XRCC6 | 2850450 3870528 | 18427 | -0.927 | -0.2596 | Yes | ||
194 | HDAC2 | 4050433 | 18455 | -0.999 | -0.2432 | Yes | ||
195 | HNRPK | 1190348 2060411 2570092 6840551 | 18560 | -1.549 | -0.2211 | Yes | ||
196 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 18570 | -1.652 | -0.1921 | Yes | ||
197 | EDF1 | 1660035 2640161 | 18572 | -1.656 | -0.1625 | Yes | ||
198 | CDKN2A | 4670215 4760047 | 18612 | -2.884 | -0.1130 | Yes | ||
199 | ARID1A | 2630022 1690551 4810110 | 18616 | -6.327 | -0.0000 | Yes |