Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | wtNotch |
GeneSet | MITOTIC_CELL_CYCLE |
Enrichment Score (ES) | -0.6011685 |
Normalized Enrichment Score (NES) | -1.5790137 |
Nominal p-value | 0.0025839794 |
FDR q-value | 0.2549405 |
FWER p-Value | 0.97 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CDK4 | 540075 4540600 | 42 | 2.101 | 0.0544 | No | ||
2 | CDK10 | 60164 1190717 3130128 3990044 | 344 | 0.815 | 0.0601 | No | ||
3 | MAD2L2 | 1240358 | 362 | 0.781 | 0.0802 | No | ||
4 | CDKN2C | 5050750 5130148 | 376 | 0.763 | 0.1000 | No | ||
5 | BCAT1 | 3290128 4050408 | 394 | 0.736 | 0.1190 | No | ||
6 | SMAD3 | 6450671 | 532 | 0.607 | 0.1279 | No | ||
7 | TARDBP | 870390 2350093 | 938 | 0.419 | 0.1173 | No | ||
8 | CHMP1A | 5550441 | 1022 | 0.394 | 0.1235 | No | ||
9 | CDC25B | 6940102 | 1428 | 0.308 | 0.1098 | No | ||
10 | MAP3K11 | 7000039 | 1620 | 0.273 | 0.1069 | No | ||
11 | CHFR | 3390050 6450300 6450736 | 2032 | 0.211 | 0.0903 | No | ||
12 | POLD1 | 4830026 | 2120 | 0.200 | 0.0910 | No | ||
13 | E2F1 | 5360093 | 2480 | 0.155 | 0.0758 | No | ||
14 | TGFB1 | 1940162 | 2566 | 0.146 | 0.0751 | No | ||
15 | ASNS | 110368 7100687 | 2752 | 0.128 | 0.0685 | No | ||
16 | CDKN2D | 6040035 | 2854 | 0.118 | 0.0663 | No | ||
17 | NUMA1 | 6520576 | 3219 | 0.092 | 0.0491 | No | ||
18 | CDK6 | 4920253 | 3448 | 0.079 | 0.0389 | No | ||
19 | APBB1 | 2690338 | 3615 | 0.071 | 0.0318 | No | ||
20 | DCTN2 | 540471 3780717 | 4018 | 0.057 | 0.0116 | No | ||
21 | CUL2 | 4200278 | 4216 | 0.051 | 0.0023 | No | ||
22 | TPD52L1 | 4590711 5570575 | 4490 | 0.044 | -0.0113 | No | ||
23 | RCC1 | 2480358 | 4585 | 0.042 | -0.0152 | No | ||
24 | ACVR1 | 6840671 | 4738 | 0.039 | -0.0224 | No | ||
25 | DLG1 | 2630091 6020286 | 5078 | 0.033 | -0.0399 | No | ||
26 | ANAPC11 | 1780601 | 5099 | 0.032 | -0.0401 | No | ||
27 | CDKN2B | 6020040 | 5117 | 0.032 | -0.0401 | No | ||
28 | ANLN | 1780113 2470537 6840047 | 5124 | 0.032 | -0.0396 | No | ||
29 | UBE2C | 6130017 | 5158 | 0.031 | -0.0406 | No | ||
30 | CDCA5 | 5670131 | 5231 | 0.030 | -0.0436 | No | ||
31 | PLK1 | 1780369 2640121 | 5459 | 0.027 | -0.0552 | No | ||
32 | TBRG4 | 3610239 6370594 | 5520 | 0.026 | -0.0577 | No | ||
33 | CENPE | 2850022 | 5930 | 0.021 | -0.0793 | No | ||
34 | SPHK1 | 2470113 4230398 6220397 | 6130 | 0.020 | -0.0895 | No | ||
35 | NEK6 | 3360687 | 6249 | 0.019 | -0.0954 | No | ||
36 | PRMT5 | 2760180 4590072 | 6528 | 0.016 | -0.1100 | No | ||
37 | CUL5 | 450142 | 6562 | 0.016 | -0.1113 | No | ||
38 | CLIP1 | 2850162 6770397 | 6821 | 0.014 | -0.1249 | No | ||
39 | PAFAH1B1 | 4230333 6420121 6450066 | 7240 | 0.012 | -0.1472 | No | ||
40 | NEK2 | 2120520 | 7736 | 0.010 | -0.1737 | No | ||
41 | KATNA1 | 6290048 | 7929 | 0.009 | -0.1839 | No | ||
42 | APBB2 | 5130403 | 7950 | 0.009 | -0.1847 | No | ||
43 | CETN1 | 6020056 | 7972 | 0.009 | -0.1856 | No | ||
44 | SNF1LK | 6110403 | 8069 | 0.008 | -0.1906 | No | ||
45 | TTN | 2320161 4670056 6550026 | 8482 | 0.007 | -0.2127 | No | ||
46 | CDKN3 | 110520 | 8494 | 0.007 | -0.2131 | No | ||
47 | KIF11 | 5390139 | 9250 | 0.004 | -0.2538 | No | ||
48 | FOXC1 | 580239 | 9318 | 0.004 | -0.2573 | No | ||
49 | POLA1 | 4760541 | 9613 | 0.003 | -0.2732 | No | ||
50 | BUB1 | 5390270 | 10161 | 0.002 | -0.3027 | No | ||
51 | EREG | 50519 4920129 | 10683 | 0.000 | -0.3309 | No | ||
52 | BTG3 | 7050079 | 10952 | -0.001 | -0.3453 | No | ||
53 | RAN | 2260446 4590647 | 11821 | -0.003 | -0.3922 | No | ||
54 | ANAPC10 | 870086 1170037 2260129 | 11836 | -0.003 | -0.3929 | No | ||
55 | PAM | 5290528 | 11858 | -0.003 | -0.3939 | No | ||
56 | CENPF | 5050088 | 11942 | -0.004 | -0.3983 | No | ||
57 | TTK | 3800129 | 12142 | -0.004 | -0.4090 | No | ||
58 | KIF2C | 6940082 | 12263 | -0.005 | -0.4153 | No | ||
59 | EPGN | 6980450 | 13267 | -0.010 | -0.4693 | No | ||
60 | NBN | 730538 2470619 4780594 | 13305 | -0.010 | -0.4710 | No | ||
61 | KIF15 | 610731 4070731 6520014 | 13401 | -0.011 | -0.4759 | No | ||
62 | CDC23 | 3190593 | 13446 | -0.011 | -0.4779 | No | ||
63 | CDKN1A | 4050088 6400706 | 13471 | -0.011 | -0.4789 | No | ||
64 | ATM | 3610110 4050524 | 13898 | -0.015 | -0.5015 | No | ||
65 | DCTN3 | 6840131 | 13908 | -0.015 | -0.5016 | No | ||
66 | FBXO5 | 2630551 | 13931 | -0.016 | -0.5024 | No | ||
67 | PML | 50093 2190435 2450402 3840082 | 13951 | -0.016 | -0.5030 | No | ||
68 | USH1C | 1570372 4230364 | 14182 | -0.019 | -0.5149 | No | ||
69 | CDC25C | 2570673 4760161 6520707 | 14329 | -0.021 | -0.5222 | No | ||
70 | CDKN1B | 3800025 6450044 | 14515 | -0.024 | -0.5316 | No | ||
71 | NPM2 | 6040139 | 14553 | -0.025 | -0.5329 | No | ||
72 | SMC3 | 870546 1400411 5700039 6450577 | 14645 | -0.027 | -0.5371 | No | ||
73 | TGFA | 1570332 | 14731 | -0.029 | -0.5409 | No | ||
74 | PIN1 | 2970408 | 14788 | -0.031 | -0.5431 | No | ||
75 | DDX11 | 6590671 | 14823 | -0.032 | -0.5441 | No | ||
76 | GFI1B | 4570131 | 14934 | -0.035 | -0.5491 | No | ||
77 | ACVR1B | 3610446 5570195 | 15239 | -0.047 | -0.5643 | No | ||
78 | CDK2 | 130484 2260301 4010088 5050110 | 15285 | -0.049 | -0.5654 | No | ||
79 | RAD17 | 5220739 | 15306 | -0.049 | -0.5651 | No | ||
80 | LATS2 | 4480593 6020494 | 15332 | -0.051 | -0.5651 | No | ||
81 | NOLC1 | 2350195 | 15646 | -0.070 | -0.5802 | No | ||
82 | GFI1 | 730180 | 15648 | -0.070 | -0.5783 | No | ||
83 | PPP5C | 3130047 | 15659 | -0.071 | -0.5770 | No | ||
84 | KIF22 | 1190368 | 15776 | -0.079 | -0.5811 | No | ||
85 | SSSCA1 | 1240402 780309 | 15875 | -0.086 | -0.5841 | No | ||
86 | CUL4A | 1170088 2320008 2470278 | 15889 | -0.087 | -0.5824 | No | ||
87 | EGF | 5220154 | 15914 | -0.089 | -0.5813 | No | ||
88 | SMC4 | 5910240 | 15937 | -0.091 | -0.5801 | No | ||
89 | CIT | 2370601 | 15947 | -0.091 | -0.5781 | No | ||
90 | SUGT1 | 1690670 | 15953 | -0.092 | -0.5759 | No | ||
91 | CCNA2 | 5290075 | 16158 | -0.110 | -0.5840 | No | ||
92 | CDK2AP1 | 2340156 | 16382 | -0.134 | -0.5924 | No | ||
93 | STMN1 | 1990717 | 16393 | -0.135 | -0.5893 | No | ||
94 | ABL1 | 1050593 2030050 4010114 | 16410 | -0.138 | -0.5865 | No | ||
95 | KNTC1 | 430079 | 16683 | -0.178 | -0.5964 | Yes | ||
96 | CD28 | 1400739 4210093 | 16693 | -0.179 | -0.5920 | Yes | ||
97 | CDC16 | 1940706 | 16789 | -0.194 | -0.5919 | Yes | ||
98 | BIRC5 | 110408 580014 1770632 | 16855 | -0.207 | -0.5899 | Yes | ||
99 | KHDRBS1 | 1240403 6040040 | 16901 | -0.215 | -0.5865 | Yes | ||
100 | DLG7 | 3120041 | 16935 | -0.220 | -0.5823 | Yes | ||
101 | AURKA | 780537 | 16964 | -0.225 | -0.5778 | Yes | ||
102 | NDC80 | 4120465 | 17235 | -0.283 | -0.5847 | Yes | ||
103 | ZWINT | 6940670 | 17240 | -0.284 | -0.5773 | Yes | ||
104 | PCBP4 | 6350722 | 17598 | -0.387 | -0.5862 | Yes | ||
105 | PPP6C | 2450670 | 17626 | -0.399 | -0.5769 | Yes | ||
106 | MPHOSPH6 | 5570164 | 17770 | -0.450 | -0.5725 | Yes | ||
107 | POLE | 6020538 | 17772 | -0.451 | -0.5604 | Yes | ||
108 | ANAPC5 | 730164 7100685 | 17854 | -0.485 | -0.5517 | Yes | ||
109 | ANAPC4 | 4540338 | 17861 | -0.487 | -0.5389 | Yes | ||
110 | CUL1 | 1990632 | 17893 | -0.503 | -0.5270 | Yes | ||
111 | SKP2 | 360711 380093 4810368 | 17931 | -0.521 | -0.5150 | Yes | ||
112 | KPNA2 | 3450114 | 17970 | -0.540 | -0.5025 | Yes | ||
113 | MAD2L1 | 4480725 | 18047 | -0.583 | -0.4909 | Yes | ||
114 | NCAPH | 6220435 | 18140 | -0.637 | -0.4787 | Yes | ||
115 | AKAP8 | 4210026 | 18200 | -0.672 | -0.4637 | Yes | ||
116 | BUB1B | 1450288 | 18215 | -0.685 | -0.4460 | Yes | ||
117 | GSPT1 | 5420050 | 18220 | -0.689 | -0.4277 | Yes | ||
118 | TPX2 | 6420324 | 18266 | -0.736 | -0.4103 | Yes | ||
119 | KIF23 | 5570112 | 18328 | -0.792 | -0.3922 | Yes | ||
120 | ZW10 | 2900735 3520687 | 18335 | -0.804 | -0.3709 | Yes | ||
121 | PRC1 | 870092 5890204 | 18426 | -0.927 | -0.3508 | Yes | ||
122 | CDC6 | 4570296 5360600 | 18471 | -1.030 | -0.3254 | Yes | ||
123 | CUL3 | 1850520 | 18514 | -1.160 | -0.2964 | Yes | ||
124 | SMC1A | 3060600 5700148 5890113 6370154 | 18529 | -1.261 | -0.2632 | Yes | ||
125 | CDKN1C | 6520577 | 18557 | -1.527 | -0.2235 | Yes | ||
126 | CDC7 | 4060546 4850041 | 18609 | -2.689 | -0.1537 | Yes | ||
127 | NUSAP1 | 940048 3120435 | 18611 | -2.829 | -0.0775 | Yes | ||
128 | CDKN2A | 4670215 4760047 | 18612 | -2.884 | 0.0002 | Yes |