Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | SHEPARD_CRASH_AND_BURN_MUT_VS_WT_UP |
Enrichment Score (ES) | 0.6369491 |
Normalized Enrichment Score (NES) | 1.5949028 |
Nominal p-value | 0.0 |
FDR q-value | 0.2402308 |
FWER p-Value | 0.97 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MIDN | 2260132 5220377 | 10 | 3.548 | 0.1098 | Yes | ||
2 | IGF2 | 6510020 | 26 | 2.564 | 0.1887 | Yes | ||
3 | PTP4A3 | 3780504 6400364 | 36 | 2.374 | 0.2620 | Yes | ||
4 | DSCR1 | 4540048 6220039 | 81 | 1.573 | 0.3086 | Yes | ||
5 | KLF2 | 6860270 | 91 | 1.525 | 0.3555 | Yes | ||
6 | CLDN4 | 4920739 | 151 | 1.162 | 0.3884 | Yes | ||
7 | HES1 | 4810280 | 196 | 1.054 | 0.4188 | Yes | ||
8 | DUSP4 | 2690044 2850593 | 199 | 1.050 | 0.4514 | Yes | ||
9 | EGR1 | 4610347 | 214 | 1.010 | 0.4820 | Yes | ||
10 | HIST1H3B | 4780092 | 252 | 0.956 | 0.5097 | Yes | ||
11 | IMPDH1 | 3190735 7050546 | 322 | 0.853 | 0.5325 | Yes | ||
12 | BAX | 3830008 | 613 | 0.553 | 0.5340 | Yes | ||
13 | CEBPB | 2970019 | 760 | 0.485 | 0.5412 | Yes | ||
14 | ELOVL1 | 2450019 4760138 5340685 | 778 | 0.478 | 0.5552 | Yes | ||
15 | PLK3 | 2640592 | 782 | 0.475 | 0.5698 | Yes | ||
16 | GPD1 | 2480095 | 783 | 0.474 | 0.5845 | Yes | ||
17 | SGK | 1400131 2480056 | 946 | 0.418 | 0.5888 | Yes | ||
18 | MRPS18A | 6770433 | 1130 | 0.366 | 0.5902 | Yes | ||
19 | SHMT1 | 5900132 | 1264 | 0.342 | 0.5937 | Yes | ||
20 | MRPS18B | 5570086 | 1276 | 0.340 | 0.6037 | Yes | ||
21 | WBSCR22 | 3130070 4120551 5570433 | 1306 | 0.333 | 0.6125 | Yes | ||
22 | TUBA8 | 3710484 | 1513 | 0.291 | 0.6104 | Yes | ||
23 | MYBBP1A | 110592 2570435 2900711 | 1594 | 0.277 | 0.6147 | Yes | ||
24 | ITGB4BP | 1400541 | 1622 | 0.272 | 0.6217 | Yes | ||
25 | MRPL12 | 3120112 | 1636 | 0.270 | 0.6294 | Yes | ||
26 | SERPINH1 | 6130014 | 1651 | 0.267 | 0.6369 | Yes | ||
27 | MMP2 | 2570603 | 2193 | 0.190 | 0.6136 | No | ||
28 | BRF1 | 2100047 | 2210 | 0.189 | 0.6186 | No | ||
29 | DRG2 | 6770563 | 2300 | 0.177 | 0.6193 | No | ||
30 | MRPS26 | 4120113 | 2485 | 0.154 | 0.6142 | No | ||
31 | CIC | 6370161 | 2538 | 0.149 | 0.6160 | No | ||
32 | PIM1 | 630047 | 2596 | 0.143 | 0.6174 | No | ||
33 | GADD45B | 2350408 | 2740 | 0.128 | 0.6136 | No | ||
34 | SLC12A7 | 6860079 | 2754 | 0.127 | 0.6169 | No | ||
35 | ATPIF1 | 7050577 | 2839 | 0.119 | 0.6160 | No | ||
36 | CYR61 | 1240408 5290026 4120452 6550008 | 2959 | 0.109 | 0.6130 | No | ||
37 | HSPA4 | 1050170 3450309 | 3144 | 0.098 | 0.6061 | No | ||
38 | WDR8 | 520377 6200093 | 3274 | 0.089 | 0.6019 | No | ||
39 | JUNB | 4230048 | 3298 | 0.088 | 0.6034 | No | ||
40 | MMP9 | 580338 | 3401 | 0.082 | 0.6004 | No | ||
41 | TAF9 | 1850458 3830136 | 3436 | 0.080 | 0.6011 | No | ||
42 | TP53 | 6130707 | 3540 | 0.075 | 0.5978 | No | ||
43 | EIF4E | 1580403 70133 6380215 | 3677 | 0.069 | 0.5926 | No | ||
44 | JDP2 | 2360500 | 3679 | 0.069 | 0.5947 | No | ||
45 | FOS | 1850315 | 3778 | 0.065 | 0.5915 | No | ||
46 | TOMM20 | 6510113 | 4429 | 0.045 | 0.5577 | No | ||
47 | SNAI1 | 6590253 | 4929 | 0.035 | 0.5318 | No | ||
48 | MYOG | 3190672 | 5011 | 0.034 | 0.5285 | No | ||
49 | PTGES2 | 4210097 | 5119 | 0.032 | 0.5237 | No | ||
50 | DDX51 | 5550044 6350270 6590750 | 5420 | 0.027 | 0.5083 | No | ||
51 | ABCF2 | 630040 3140035 6450601 | 5606 | 0.025 | 0.4991 | No | ||
52 | C6 | 1770154 2900129 | 5689 | 0.024 | 0.4954 | No | ||
53 | PDLIM3 | 1410095 | 5710 | 0.024 | 0.4951 | No | ||
54 | PPP1R14A | 870114 4760187 | 5741 | 0.024 | 0.4942 | No | ||
55 | MRPL52 | 1170204 | 5769 | 0.023 | 0.4935 | No | ||
56 | JUN | 840170 | 6162 | 0.019 | 0.4729 | No | ||
57 | SIX2 | 1450551 | 6301 | 0.018 | 0.4660 | No | ||
58 | FBL | 5130020 | 6451 | 0.017 | 0.4584 | No | ||
59 | ATF3 | 1940546 | 6485 | 0.017 | 0.4572 | No | ||
60 | CYP26A1 | 380022 2690600 | 6559 | 0.016 | 0.4537 | No | ||
61 | CDX4 | 6380164 | 7123 | 0.012 | 0.4237 | No | ||
62 | HSPA1L | 4010538 | 7148 | 0.012 | 0.4228 | No | ||
63 | ITGB1BP3 | 60441 730750 | 7222 | 0.012 | 0.4192 | No | ||
64 | BOP1 | 4810040 | 7467 | 0.011 | 0.4063 | No | ||
65 | WDR12 | 4560722 | 7798 | 0.009 | 0.3888 | No | ||
66 | ODC1 | 5670168 | 8053 | 0.008 | 0.3753 | No | ||
67 | B3GNT1 | 2350446 | 8163 | 0.008 | 0.3697 | No | ||
68 | RRS1 | 4560551 | 8295 | 0.007 | 0.3628 | No | ||
69 | BMP2 | 6620687 | 8306 | 0.007 | 0.3625 | No | ||
70 | IBRDC2 | 5130041 | 8456 | 0.007 | 0.3546 | No | ||
71 | CYP24A1 | 2340338 | 9551 | 0.003 | 0.2956 | No | ||
72 | IGFBP1 | 5720435 | 9591 | 0.003 | 0.2936 | No | ||
73 | CTH | 1190332 5290139 | 9755 | 0.003 | 0.2849 | No | ||
74 | PHLDA2 | 4810494 | 10046 | 0.002 | 0.2692 | No | ||
75 | RBP4 | 4540131 | 10088 | 0.002 | 0.2671 | No | ||
76 | ADAM10 | 3780156 | 10223 | 0.001 | 0.2599 | No | ||
77 | BTG2 | 2350411 | 10910 | -0.001 | 0.2228 | No | ||
78 | CYP27B1 | 5270114 5360010 | 11020 | -0.001 | 0.2169 | No | ||
79 | FST | 1110600 | 11431 | -0.002 | 0.1948 | No | ||
80 | BXDC1 | 2640068 | 11552 | -0.002 | 0.1884 | No | ||
81 | SSR1 | 5890100 | 12023 | -0.004 | 0.1631 | No | ||
82 | ANGPTL3 | 6180497 | 12533 | -0.006 | 0.1358 | No | ||
83 | RERG | 5910324 | 12736 | -0.007 | 0.1251 | No | ||
84 | NOG | 2320609 | 12769 | -0.007 | 0.1236 | No | ||
85 | AP1M2 | 2900138 6040324 6370537 | 12797 | -0.007 | 0.1223 | No | ||
86 | PTGS2 | 2510301 3170369 | 13030 | -0.009 | 0.1101 | No | ||
87 | ING5 | 3830440 5910239 6200471 6650576 | 13119 | -0.009 | 0.1056 | No | ||
88 | ANKRD22 | 4480746 | 13301 | -0.010 | 0.0961 | No | ||
89 | SLC12A3 | 1980592 2350056 | 13987 | -0.016 | 0.0596 | No | ||
90 | SEC23B | 3390632 3840497 | 14424 | -0.023 | 0.0367 | No | ||
91 | CCNG1 | 870402 1500685 6110594 | 14454 | -0.023 | 0.0359 | No | ||
92 | ARMET | 5130670 | 14968 | -0.036 | 0.0093 | No | ||
93 | AP3M1 | 5340433 | 15043 | -0.039 | 0.0065 | No | ||
94 | SRPRB | 1500138 5130156 5910064 | 15142 | -0.043 | 0.0025 | No | ||
95 | NOL7 | 6520332 | 15385 | -0.053 | -0.0089 | No | ||
96 | RPS27L | 50577 | 15514 | -0.061 | -0.0139 | No | ||
97 | MDM2 | 3450053 5080138 | 15571 | -0.065 | -0.0149 | No | ||
98 | CORT | 360008 2340092 | 15580 | -0.066 | -0.0133 | No | ||
99 | NOLA1 | 730093 | 15706 | -0.074 | -0.0178 | No | ||
100 | SLC3A2 | 5270358 | 15876 | -0.086 | -0.0243 | No | ||
101 | FN1 | 1170601 2970647 6220288 6940037 | 15920 | -0.090 | -0.0238 | No | ||
102 | SLC16A6 | 1690156 | 16092 | -0.104 | -0.0298 | No | ||
103 | DNAJA3 | 1980671 6220338 | 16162 | -0.111 | -0.0301 | No | ||
104 | AK3L1 | 7100601 | 16260 | -0.120 | -0.0316 | No | ||
105 | CCNG2 | 3190095 | 16329 | -0.128 | -0.0313 | No | ||
106 | PES1 | 2470427 | 16337 | -0.129 | -0.0277 | No | ||
107 | STARD10 | 1400619 4570170 | 16395 | -0.135 | -0.0266 | No | ||
108 | PPAN | 540398 | 16437 | -0.141 | -0.0244 | No | ||
109 | CIRH1A | 2340372 | 16803 | -0.196 | -0.0380 | No | ||
110 | CASP8 | 4850154 | 16951 | -0.223 | -0.0390 | No | ||
111 | NOL6 | 2810504 3120050 3840021 6860315 | 16959 | -0.224 | -0.0324 | No | ||
112 | MKNK2 | 1240020 5270092 | 17203 | -0.275 | -0.0370 | No | ||
113 | PFKFB3 | 630706 | 17382 | -0.327 | -0.0365 | No | ||
114 | CYP51A1 | 4590427 | 17383 | -0.327 | -0.0263 | No | ||
115 | TOB1 | 4150138 | 17435 | -0.340 | -0.0185 | No | ||
116 | VRK2 | 3800692 6940056 | 17497 | -0.354 | -0.0108 | No | ||
117 | MRPL22 | 6400520 | 17511 | -0.357 | -0.0004 | No | ||
118 | PINX1 | 3360154 | 17561 | -0.372 | 0.0085 | No | ||
119 | FTSJ3 | 3140100 | 17600 | -0.388 | 0.0185 | No | ||
120 | POP4 | 4560600 | 17601 | -0.388 | 0.0306 | No | ||
121 | ETF1 | 6770075 | 18309 | -0.780 | 0.0166 | No |