Details for gene set ICHIBA

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch
Phenotype	phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch
Upregulated in class	truncNotch
GeneSet	ICHIBA_GVHD
Enrichment Score (ES)	0.6133041
Normalized Enrichment Score (NES)	1.6466789
Nominal p-value	0.0
FDR q-value	0.16560695
FWER p-Value	0.727

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLC11A1	940286 2810435 6370647	15	3.189	0.0403	Yes
2	CYB561	5080341	18	2.891	0.0775	Yes
3	SCOTIN	670332 3450167 6450022	22	2.740	0.1127	Yes
4	HBA-A1	360435	45	2.070	0.1382	Yes
5	FLOT1	1660575 1690040	83	1.559	0.1563	Yes
6	S100A8	70112	85	1.547	0.1762	Yes
7	KLF2	6860270	91	1.525	0.1956	Yes
8	HES6	540411 6550504	96	1.504	0.2148	Yes
9	PLAC8	2900019	111	1.382	0.2319	Yes
10	CAMP	6290735	160	1.123	0.2437	Yes
11	SIRPA	130465 5700332	178	1.090	0.2569	Yes
12	PDZK1	2320128	181	1.085	0.2708	Yes
13	LTF	6770364	189	1.067	0.2841	Yes
14	HBB-B2	2450131	216	1.007	0.2957	Yes
15	ELA1	3390167	289	0.914	0.3036	Yes
16	CTSC	2230739 4670408	294	0.907	0.3151	Yes
17	LGMN	3610301	296	0.907	0.3267	Yes
18	C1QC	5700131	304	0.890	0.3378	Yes
19	S100A9	7050528	331	0.837	0.3472	Yes
20	H2-DMA	6290463	347	0.809	0.3568	Yes
21	TFF3	1580129	389	0.741	0.3641	Yes
22	NGP	2640133	391	0.739	0.3736	Yes
23	C1QB	5910292	396	0.735	0.3829	Yes
24	SLPI	2120446	404	0.723	0.3918	Yes
25	C1QA	5390687	407	0.722	0.4010	Yes
26	CCL4	50368 430047	440	0.680	0.4081	Yes
27	CRYL1	1340427	465	0.660	0.4153	Yes
28	H2-EB1	2350079	484	0.642	0.4226	Yes
29	LGALS3BP	840692	535	0.606	0.4277	Yes
30	ISG15	3170093	549	0.597	0.4347	Yes
31	GPX3	1340450	566	0.585	0.4413	Yes
32	CD68	6350450	575	0.578	0.4484	Yes
33	S100A6	1690204	593	0.566	0.4547	Yes
34	HP	2940551 6350068	594	0.566	0.4620	Yes
35	SAA3P	6510390	598	0.563	0.4691	Yes
36	NXN	2350180	601	0.562	0.4763	Yes
37	UBE1L	6660242	686	0.514	0.4783	Yes
38	H2-AA	5290673	694	0.511	0.4845	Yes
39	PLD3	510041	701	0.508	0.4908	Yes
40	TYROBP	2230020	716	0.501	0.4965	Yes
41	VEGFB	5360152	718	0.500	0.5029	Yes
42	ALAS2	6550176	731	0.496	0.5086	Yes
43	SERPINA3G	610600	758	0.486	0.5135	Yes
44	IFI35	4230739	807	0.464	0.5168	Yes
45	SNX12	4060026	827	0.458	0.5217	Yes
46	CTPS	70451 1740132	836	0.456	0.5272	Yes
47	LGALS3	2120239	852	0.451	0.5322	Yes
48	TSPAN4	5050647	868	0.445	0.5371	Yes
49	MT1A	4850164	869	0.444	0.5428	Yes
50	LITAF	6940671	876	0.443	0.5482	Yes
51	SLFN2	3120114	943	0.419	0.5500	Yes
52	H2-DMB1	4760026	949	0.417	0.5551	Yes
53	SLC25A10	1400609	961	0.415	0.5599	Yes
54	CFP	2100619	965	0.414	0.5651	Yes
55	H2-AB1	4230427	988	0.407	0.5691	Yes
56	QSCN6	3120441	1026	0.393	0.5722	Yes
57	CYBA	4760739	1037	0.389	0.5766	Yes
58	TAP1	4050047	1045	0.387	0.5812	Yes
59	IRF1	2340152 3450592 6290121 6980577	1095	0.374	0.5834	Yes
60	ITPK1	3360056	1099	0.374	0.5881	Yes
61	ELAC2	3440167 4730546	1187	0.356	0.5879	Yes
62	D12ERTD647E	5290364	1285	0.338	0.5870	Yes
63	FBXO21	6550070	1343	0.326	0.5881	Yes
64	PSMB8	2850707	1348	0.325	0.5920	Yes
65	PRTN3	6900670	1382	0.318	0.5943	Yes
66	CD14	5570600	1422	0.309	0.5962	Yes
67	PTPN1	2650056	1436	0.306	0.5994	Yes
68	CCL7	2650519	1443	0.305	0.6031	Yes
69	CTSE	2030292	1483	0.298	0.6048	Yes
70	FKBP11	3170575	1537	0.287	0.6056	Yes
71	IRF7	1570605	1645	0.268	0.6032	Yes
72	TAPBP	1980110	1701	0.261	0.6036	Yes
73	CCL5	3710397	1721	0.258	0.6059	Yes
74	MT2A	6860286	1753	0.253	0.6075	Yes
75	S100A4	3780113	1791	0.248	0.6086	Yes
76	SCD5	5690309 5220332 7040278	1821	0.242	0.6102	Yes
77	IRF8	610161	1822	0.242	0.6133	Yes
78	CD53	5550162	1893	0.232	0.6125	No
79	VCAM1	2900450	1949	0.222	0.6123	No
80	RRAS	4150609	2139	0.197	0.6046	No
81	CLIC1	110600	2161	0.194	0.6059	No
82	NFKBIA	1570152	2224	0.187	0.6050	No
83	LCK	3360142	2265	0.181	0.6051	No
84	WARS	2570717 3290139	2368	0.168	0.6017	No
85	IL18BP	3450128	2372	0.167	0.6037	No
86	SOCS1	730139	2481	0.154	0.5998	No
87	SELPL	1770167	2525	0.150	0.5994	No
88	1110038F14RIK	1190075	2627	0.139	0.5957	No
89	COL4A1	1740575	2756	0.127	0.5903	No
90	G6PC	430093	2831	0.120	0.5879	No
91	GRN	4050239	2841	0.119	0.5889	No
92	HPXN	3440114	2858	0.118	0.5895	No
93	PRM3	4810577	2960	0.109	0.5854	No
94	NOL1	4570576 4920044	2962	0.109	0.5868	No
95	CD7	3140465	2996	0.106	0.5864	No
96	TMSB10	2340484	3018	0.105	0.5866	No
97	LAPTM5	5550372	3031	0.105	0.5873	No
98	CXCL1	2690537	3037	0.104	0.5884	No
99	PSMB10	630504 6510039	3078	0.102	0.5875	No
100	IRGM	6110148 6660685	3182	0.096	0.5831	No
101	D17H6S56E-5	4760095	3234	0.092	0.5815	No
102	MARCO	870056	3248	0.091	0.5820	No
103	NAT8	6520500	3275	0.089	0.5817	No
104	AKAP9	510184 2060195 2470136 4280048	3578	0.073	0.5662	No
105	EMR1	70136 1500592	3710	0.068	0.5599	No
106	MS4A6C	3870427	3774	0.065	0.5573	No
107	ITGB2	6380348	3811	0.064	0.5562	No
108	CCR1	3440672	3826	0.063	0.5562	No
109	CTSS	1740056	3943	0.059	0.5507	No
110	PROM1	3170537	4048	0.056	0.5457	No
111	NR1D1	2360471 770746 6590204	4145	0.053	0.5412	No
112	LPHN1	1400113 3130301	4202	0.051	0.5388	No
113	CYP8B1	2350369	4356	0.047	0.5310	No
114	CXCL9	1570673	4532	0.043	0.5220	No
115	FAS	4480112 6110040	4574	0.042	0.5203	No
116	CYBB	3870020	4894	0.036	0.5034	No
117	FCGR1	6100176	4923	0.035	0.5023	No
118	SAMHD1	2350338 5390451	4934	0.035	0.5022	No
119	MKLN1	70504 1850129	4990	0.034	0.4997	No
120	S100A11	2260064	5045	0.033	0.4971	No
121	NNMT	450471	5069	0.033	0.4963	No
122	KRT1-18	4060563	5089	0.032	0.4957	No
123	CYP2B10	3390100	5106	0.032	0.4952	No
124	IGFALS	6350195	5144	0.031	0.4936	No
125	OSBPL5	3840537 6040286	5152	0.031	0.4936	No
126	CASP1	2360546	5284	0.029	0.4869	No
127	PLK1	1780369 2640121	5459	0.027	0.4777	No
128	PTGS1	730193 1780273 6450195	5635	0.025	0.4685	No
129	SCMH1	3190019 6770450	5783	0.023	0.4608	No
130	BMPR2	5340066 6960328	5843	0.022	0.4579	No
131	SERPINA10	2360114	6140	0.020	0.4420	No
132	ORM2	2100048	6254	0.019	0.4360	No
133	ORM3	3310128	6260	0.018	0.4360	No
134	PSMB9	6980471	6277	0.018	0.4354	No
135	SULT4A1	5270161	6296	0.018	0.4346	No
136	IL18R1	270546	6415	0.017	0.4284	No
137	HCK	4230592	6475	0.017	0.4254	No
138	CYP26A1	380022 2690600	6559	0.016	0.4211	No
139	SAA2	1090139	6568	0.016	0.4209	No
140	LBP	6860019	6634	0.016	0.4175	No
141	SLC1A2	2230520	6735	0.015	0.4123	No
142	MS4A4D	4850632	7195	0.012	0.3874	No
143	CYP2B13	5420672	7366	0.011	0.3783	No
144	CTLA2B	4210168	7445	0.011	0.3741	No
145	CD5L	4070605	7492	0.011	0.3718	No
146	SH3GL1	6110154	7744	0.009	0.3582	No
147	CYP4A10	3170288 6130131	7900	0.009	0.3499	No
148	CYP7B1	1190309	7917	0.009	0.3491	No
149	SLC26A1	2190142	7918	0.009	0.3492	No
150	GBP1	780075	7978	0.009	0.3461	No
151	ADRB3	6900072	8470	0.007	0.3194	No
152	RELN	6510037	8545	0.006	0.3155	No
153	GHR	2260156	8888	0.005	0.2969	No
154	FGL2	3170731	8916	0.005	0.2955	No
155	ELOVL2	5720064	8918	0.005	0.2955	No
156	MUP5	6770279	8988	0.005	0.2918	No
157	GBP2	50301	9132	0.005	0.2840	No
158	HSD3B2	70068 770037 4120114 4230170 5690333	9324	0.004	0.2737	No
159	CCL6	6660390	9386	0.004	0.2704	No
160	CXCL10	2450408	9769	0.003	0.2496	No
161	TMSB4X	6620114	9846	0.002	0.2455	No
162	RPS6KC1	5220619	9956	0.002	0.2396	No
163	TGTP	2810138	9981	0.002	0.2383	No
164	PKLR	1170400 2470114	10072	0.002	0.2334	No
165	KEG1	6940603	10125	0.002	0.2306	No
166	GSTM6	3940358 5670019	10224	0.001	0.2253	No
167	CAR14	1450528	10291	0.001	0.2217	No
168	SULT2A2	2650397	10623	0.000	0.2036	No
169	IL1RN	2370333	10640	0.000	0.2028	No
170	ACTL7B	460341	10752	-0.000	0.1967	No
171	PROCR	4920687	10764	-0.000	0.1961	No
172	BTG2	2350411	10910	-0.001	0.1882	No
173	LIPC	2690497	10923	-0.001	0.1876	No
174	5830411E10RIK	2940053	11030	-0.001	0.1818	No
175	PSCDBP	1780408	11072	-0.001	0.1796	No
176	DCLRE1A	5890427	11245	-0.001	0.1702	No
177	PAX3	50551	11246	-0.001	0.1702	No
178	IFI202B	4070398	11342	-0.002	0.1651	No
179	HSD17B2	3800541	11370	-0.002	0.1636	No
180	H2-D1	2190725	11372	-0.002	0.1636	No
181	IFIT3	2450278 3190113 6200113	11515	-0.002	0.1559	No
182	ZIC3	380020	11531	-0.002	0.1551	No
183	TLR6	510102 3390148	11608	-0.003	0.1510	No
184	GIMAP4	5570673 6550041	11669	-0.003	0.1477	No
185	IFIT1	5270373	11718	-0.003	0.1451	No
186	FABP1	6940035	11818	-0.003	0.1398	No
187	HAO3	6100368	11827	-0.003	0.1394	No
188	PIRA1	4120632	11877	-0.003	0.1368	No
189	HSD3B3	4570113	11918	-0.004	0.1346	No
190	CASP6	5690239 6420551	11919	-0.004	0.1347	No
191	CYP2B9	360152	12065	-0.004	0.1268	No
192	PRLR	1980647 1990097	12161	-0.005	0.1217	No
193	ODZ3	3060725 6450292	12226	-0.005	0.1183	No
194	MUP3	4480152	12280	-0.005	0.1154	No
195	A130022J15RIK	4150494	12332	-0.005	0.1127	No
196	LIFR	3360068 3830102	12436	-0.006	0.1072	No
197	ORM1	1500563	12483	-0.006	0.1047	No
198	CES3	5050167 3290458	12485	-0.006	0.1048	No
199	KLF10	4850056	12626	-0.006	0.0972	No
200	PDK3	510484	12729	-0.007	0.0917	No
201	GAS1	2120504	12734	-0.007	0.0916	No
202	CCL2	4760019	12771	-0.007	0.0897	No
203	VNN1	3940400	12840	-0.007	0.0861	No
204	SC5DL	6650390	12844	-0.007	0.0861	No
205	SERPINA6	1850707	13168	-0.009	0.0686	No
206	CRYAA	2030164	13173	-0.009	0.0685	No
207	MSR1	940538	13292	-0.010	0.0622	No
208	DIO1	4570279 5290112 5420148	13373	-0.011	0.0579	No
209	MUP4	670253 4560487	13513	-0.012	0.0505	No
210	H2-EA	3870301	13584	-0.012	0.0469	No
211	AVPR1A	2120300	13659	-0.013	0.0430	No
212	FPR1	3800577	13668	-0.013	0.0427	No
213	GDF5	510440	13713	-0.013	0.0405	No
214	UBD	5570632	13836	-0.015	0.0340	No
215	PPP1R3C	2640170	13843	-0.015	0.0339	No
216	GBP4	6520471 1980670	14076	-0.017	0.0215	No
217	OAT	540632	14150	-0.018	0.0177	No
218	CSF1R	2340110 6420408	14324	-0.021	0.0086	No
219	LY75	1990358 4590136	14364	-0.022	0.0067	No
220	CHI3L3	2120332	14367	-0.022	0.0069	No
221	LCP2	2680066 6650707	14428	-0.023	0.0039	No
222	MCM10	4920632	14437	-0.023	0.0038	No
223	APBB1IP	4560441 4570706 6520739	14445	-0.023	0.0037	No
224	GP49A	1940390	14463	-0.023	0.0030	No
225	ATP11A	1240717 5570603	14510	-0.024	0.0009	No
226	PBEF1	1090278	14713	-0.029	-0.0098	No
227	CDC5L	3130446 3390025 6400204	14776	-0.030	-0.0128	No
228	RPL22	4070070	14858	-0.033	-0.0168	No
229	MARVELD1	6110309	14884	-0.034	-0.0177	No
230	MMP12	4920070	14894	-0.034	-0.0178	No
231	NFKBIZ	2970450	14916	-0.034	-0.0185	No
232	PAPSS2	870113	15195	-0.045	-0.0330	No
233	NCOA3	4540195	15205	-0.045	-0.0329	No
234	GLT25D1	540088	15351	-0.052	-0.0402	No
235	XDH	6840446	15368	-0.053	-0.0404	No
236	ADCY9	5690168	15419	-0.055	-0.0424	No
237	LRG1	5690605	15437	-0.056	-0.0426	No
238	STX3	1190563 2640215	15443	-0.057	-0.0421	No
239	AIF1	130332 5220017	15550	-0.064	-0.0471	No
240	UBAP2L	4120128 6650133	15569	-0.065	-0.0472	No
241	IL6ST	5890047	15658	-0.071	-0.0511	No
242	SNX10	3800035	15677	-0.072	-0.0512	No
243	SPTLC2	6840324 520017	15679	-0.072	-0.0503	No
244	LY86	2230093	15717	-0.075	-0.0514	No
245	CD52	5910242	15758	-0.078	-0.0526	No
246	GLTP	3440603	16036	-0.099	-0.0664	No
247	PPP1R2	3710278 1400725	16214	-0.116	-0.0745	No
248	9830147J24RIK	2690451	16258	-0.120	-0.0753	No
249	AIM1	2810142	16278	-0.122	-0.0748	No
250	STAT1	6510204 6590553	16359	-0.131	-0.0775	No
251	LPL	1450735 2970706	16371	-0.133	-0.0764	No
252	RPAP1	4670152 6450068	16481	-0.148	-0.0804	No
253	POM121	70152	16607	-0.167	-0.0851	No
254	ACSL1	2900520	16682	-0.177	-0.0868	No
255	BC004022	3440142	16818	-0.200	-0.0916	No
256	BIRC5	110408 580014 1770632	16855	-0.207	-0.0909	No
257	PSME2	4850086	16903	-0.215	-0.0907	No
258	4921506I22RIK	1340279	16967	-0.226	-0.0912	No
259	HMGCS2	770725	16969	-0.226	-0.0883	No
260	NR2F6	1340239 5670239 60338 4280088	17046	-0.241	-0.0894	No
261	1700013L23RIK	3390097	17111	-0.255	-0.0896	No
262	NEK9	3440402	17214	-0.280	-0.0915	No
263	ELOVL6	5340746	17264	-0.293	-0.0904	No
264	PTPRC	130402 5290148	17327	-0.312	-0.0898	No
265	FKBP5	2190048	17334	-0.315	-0.0861	No
266	SMOC2	1170170	17421	-0.336	-0.0864	No
267	EXOSC8	360427	17436	-0.340	-0.0828	No
268	PSME1	450193 4480035	17491	-0.353	-0.0812	No
269	IQGAP1	6660494	17508	-0.357	-0.0775	No
270	NCF4	610164	17568	-0.374	-0.0758	No
271	IFI47	3060673	17661	-0.414	-0.0755	No
272	1500011J06RIK	5130056	17803	-0.467	-0.0772	No
273	ICAM1	6980138	17815	-0.472	-0.0717	No
274	USP18	4010110	17842	-0.481	-0.0669	No
275	TAP2	2810347	17867	-0.489	-0.0619	No
276	EIF1	5080100	18118	-0.622	-0.0675	No
277	LY6A	6110605	18149	-0.642	-0.0609	No
278	ATP1B3	6040128	18305	-0.774	-0.0593	No
279	UCK1	2650398 3130113 5130725	18527	-1.253	-0.0552	No
280	MCM4	2760673 5420711	18538	-1.324	-0.0387	No
281	PKM2	6520403 70500	18563	-1.576	-0.0197	No
282	LYZS	50068 6770717	18581	-1.744	0.0019	No