Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #truncNotch_versus_wtNotch |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#truncNotch_versus_wtNotch |
Upregulated in class | truncNotch |
GeneSet | REACTOME_SIGNALING_BY_GPCR |
Enrichment Score (ES) | 0.64250535 |
Normalized Enrichment Score (NES) | 1.6273884 |
Nominal p-value | 0.0 |
FDR q-value | 0.21567382 |
FWER p-Value | 0.619 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GAL | 3930279 | 9 | 3.618 | 0.1882 | Yes | ||
2 | RHOA | 580142 5900131 5340450 | 11 | 3.476 | 0.3695 | Yes | ||
3 | GNAS | 630441 1850373 4050152 | 19 | 2.879 | 0.5192 | Yes | ||
4 | P2RY6 | 5290400 | 393 | 0.737 | 0.5375 | Yes | ||
5 | ADRB2 | 3290373 | 402 | 0.728 | 0.5750 | Yes | ||
6 | RHOG | 6760575 | 684 | 0.516 | 0.5867 | Yes | ||
7 | GNA12 | 1230301 | 737 | 0.495 | 0.6097 | Yes | ||
8 | CCR7 | 2060687 | 763 | 0.484 | 0.6336 | Yes | ||
9 | CNR2 | 2760398 | 1061 | 0.381 | 0.6375 | Yes | ||
10 | TBXA2R | 2370292 3940066 | 1293 | 0.337 | 0.6425 | Yes | ||
11 | CCL5 | 3710397 | 1721 | 0.258 | 0.6328 | No | ||
12 | GNG2 | 2230390 | 1814 | 0.243 | 0.6405 | No | ||
13 | F2 | 5720280 | 2123 | 0.199 | 0.6343 | No | ||
14 | ADRBK1 | 1340333 | 2249 | 0.183 | 0.6370 | No | ||
15 | PDYN | 5720408 | 2370 | 0.167 | 0.6393 | No | ||
16 | EDNRA | 6900133 | 2598 | 0.143 | 0.6345 | No | ||
17 | HRH2 | 3840440 | 3516 | 0.076 | 0.5888 | No | ||
18 | BDKRB1 | 730592 | 3541 | 0.075 | 0.5914 | No | ||
19 | GCGR | 6620497 | 3580 | 0.073 | 0.5931 | No | ||
20 | NTSR1 | 6510136 | 3658 | 0.070 | 0.5926 | No | ||
21 | CRHR2 | 4590672 | 3772 | 0.065 | 0.5899 | No | ||
22 | GNAZ | 6130296 | 3892 | 0.061 | 0.5866 | No | ||
23 | AVPR2 | 360064 | 3895 | 0.060 | 0.5897 | No | ||
24 | ADORA2A | 1990687 | 3929 | 0.059 | 0.5910 | No | ||
25 | ADCYAP1R1 | 3390020 4280184 5360180 | 4067 | 0.055 | 0.5865 | No | ||
26 | GRM6 | 2030398 | 4213 | 0.051 | 0.5812 | No | ||
27 | CX3CL1 | 3990707 | 4394 | 0.046 | 0.5739 | No | ||
28 | LTB4R | 1770056 | 4603 | 0.041 | 0.5648 | No | ||
29 | HTR2A | 360037 6330255 | 4780 | 0.038 | 0.5572 | No | ||
30 | AGT | 7000575 | 4988 | 0.034 | 0.5478 | No | ||
31 | AVP | 2100113 | 4998 | 0.034 | 0.5491 | No | ||
32 | GRK5 | 1940348 4670053 | 5087 | 0.032 | 0.5460 | No | ||
33 | GNAQ | 430670 4210131 5900736 | 5173 | 0.031 | 0.5430 | No | ||
34 | GLP1R | 6420528 | 5201 | 0.031 | 0.5432 | No | ||
35 | GLP2R | 4150577 5290273 7050095 | 5226 | 0.030 | 0.5434 | No | ||
36 | PTGIR | 2100563 | 5230 | 0.030 | 0.5449 | No | ||
37 | GHRHR | 3130500 4010154 | 5692 | 0.024 | 0.5211 | No | ||
38 | P2RY14 | 6100497 | 5775 | 0.023 | 0.5179 | No | ||
39 | GPR17 | 5890671 | 5867 | 0.022 | 0.5142 | No | ||
40 | TSHB | 6770500 | 5963 | 0.021 | 0.5101 | No | ||
41 | SCTR | 2940070 | 5967 | 0.021 | 0.5111 | No | ||
42 | CALCRL | 4280035 | 5969 | 0.021 | 0.5121 | No | ||
43 | IAPP | 4230040 | 5972 | 0.021 | 0.5131 | No | ||
44 | P2RY1 | 6040121 | 6025 | 0.021 | 0.5113 | No | ||
45 | KNG1 | 6400576 6770347 | 6084 | 0.020 | 0.5093 | No | ||
46 | FSHR | 610041 7040121 | 6157 | 0.019 | 0.5064 | No | ||
47 | GNAT1 | 5270048 6100170 | 6176 | 0.019 | 0.5064 | No | ||
48 | MC5R | 2640176 | 6284 | 0.018 | 0.5016 | No | ||
49 | PTGDR | 3850161 | 6297 | 0.018 | 0.5019 | No | ||
50 | AGTR1 | 4780524 2680592 | 6306 | 0.018 | 0.5024 | No | ||
51 | FSHB | 7100592 | 6350 | 0.018 | 0.5010 | No | ||
52 | XCR1 | 5080072 | 6692 | 0.015 | 0.4833 | No | ||
53 | CCKBR | 2760128 | 6896 | 0.014 | 0.4730 | No | ||
54 | DRD3 | 4780402 | 7048 | 0.013 | 0.4655 | No | ||
55 | CHRM2 | 870750 | 7089 | 0.013 | 0.4640 | No | ||
56 | CHRM5 | 5390333 | 7197 | 0.012 | 0.4589 | No | ||
57 | HCRTR2 | 2350463 | 7286 | 0.012 | 0.4547 | No | ||
58 | PPYR1 | 1410072 | 7328 | 0.011 | 0.4531 | No | ||
59 | ADORA1 | 6370520 | 7575 | 0.010 | 0.4403 | No | ||
60 | IL8RA | 1580100 | 7607 | 0.010 | 0.4392 | No | ||
61 | ADM2 | 4060102 | 7683 | 0.010 | 0.4356 | No | ||
62 | P2RY4 | 630053 | 7765 | 0.009 | 0.4317 | No | ||
63 | CALCR | 1690494 | 7822 | 0.009 | 0.4292 | No | ||
64 | MC2R | 2970504 | 7874 | 0.009 | 0.4269 | No | ||
65 | HCRTR1 | 1580273 | 7895 | 0.009 | 0.4263 | No | ||
66 | HRH1 | 840100 | 7935 | 0.009 | 0.4246 | No | ||
67 | HTR6 | 4850022 | 8142 | 0.008 | 0.4139 | No | ||
68 | CASR | 610504 | 8366 | 0.007 | 0.4022 | No | ||
69 | BAI3 | 940692 | 8550 | 0.006 | 0.3926 | No | ||
70 | GPRC6A | 4560576 | 8574 | 0.006 | 0.3917 | No | ||
71 | DARC | 3940050 | 8640 | 0.006 | 0.3885 | No | ||
72 | OPRM1 | 5360279 | 8737 | 0.006 | 0.3836 | No | ||
73 | GNGT1 | 5220156 | 8845 | 0.005 | 0.3781 | No | ||
74 | PTGFR | 3850373 | 8955 | 0.005 | 0.3724 | No | ||
75 | CCR3 | 50427 | 8997 | 0.005 | 0.3705 | No | ||
76 | OXT | 3850692 | 9042 | 0.005 | 0.3683 | No | ||
77 | CALCA | 5860167 | 9172 | 0.004 | 0.3616 | No | ||
78 | PIK3R1 | 4730671 | 9416 | 0.004 | 0.3486 | No | ||
79 | ADRA2A | 5340520 | 9678 | 0.003 | 0.3347 | No | ||
80 | HCRT | 2970463 | 10328 | 0.001 | 0.2996 | No | ||
81 | PPY | 2340373 | 10388 | 0.001 | 0.2964 | No | ||
82 | NPFF | 2030280 | 10541 | 0.001 | 0.2882 | No | ||
83 | CCR10 | 4050097 | 10634 | 0.000 | 0.2833 | No | ||
84 | TACR1 | 70358 3840411 | 10741 | -0.000 | 0.2775 | No | ||
85 | DRD1 | 430025 | 10805 | -0.000 | 0.2742 | No | ||
86 | C5AR1 | 4540402 | 10869 | -0.000 | 0.2708 | No | ||
87 | CGA | 630403 | 10967 | -0.001 | 0.2656 | No | ||
88 | VIPR2 | 6520050 | 11060 | -0.001 | 0.2606 | No | ||
89 | AKT1 | 5290746 | 11364 | -0.002 | 0.2443 | No | ||
90 | SCT | 2230348 | 11473 | -0.002 | 0.2386 | No | ||
91 | TACR3 | 4780017 | 11510 | -0.002 | 0.2367 | No | ||
92 | CRH | 3710301 | 11641 | -0.003 | 0.2298 | No | ||
93 | TACR2 | 1740358 | 11762 | -0.003 | 0.2235 | No | ||
94 | IL8RB | 450592 1170537 | 11796 | -0.003 | 0.2219 | No | ||
95 | PTGER1 | 6100132 | 11871 | -0.003 | 0.2181 | No | ||
96 | PTGER3 | 2900739 6770750 | 11977 | -0.004 | 0.2126 | No | ||
97 | EDN1 | 1770047 | 12016 | -0.004 | 0.2107 | No | ||
98 | TSHR | 1190687 5270364 | 12131 | -0.004 | 0.2048 | No | ||
99 | CCR6 | 5720368 6020176 | 12251 | -0.005 | 0.1986 | No | ||
100 | GRPR | 6020170 | 12272 | -0.005 | 0.1978 | No | ||
101 | MTNR1A | 380204 | 12324 | -0.005 | 0.1953 | No | ||
102 | OPN1SW | 6420377 | 12355 | -0.005 | 0.1939 | No | ||
103 | GIP | 3170364 | 12424 | -0.006 | 0.1906 | No | ||
104 | GALR1 | 6020452 | 12482 | -0.006 | 0.1878 | No | ||
105 | HTR1F | 670148 | 12616 | -0.006 | 0.1809 | No | ||
106 | LHB | 1450368 | 12682 | -0.007 | 0.1777 | No | ||
107 | XCL1 | 3800504 | 12744 | -0.007 | 0.1748 | No | ||
108 | NTS | 380300 2120592 | 12776 | -0.007 | 0.1735 | No | ||
109 | SST | 6590142 | 12786 | -0.007 | 0.1734 | No | ||
110 | TAC1 | 7000195 380706 | 12833 | -0.007 | 0.1713 | No | ||
111 | GNA14 | 3390017 | 12941 | -0.008 | 0.1659 | No | ||
112 | CCK | 6370368 | 12965 | -0.008 | 0.1651 | No | ||
113 | VIP | 2850647 | 13050 | -0.009 | 0.1610 | No | ||
114 | GHRH | 4570575 | 13059 | -0.009 | 0.1610 | No | ||
115 | LHCGR | 4560465 5860551 | 13296 | -0.010 | 0.1488 | No | ||
116 | CXCL11 | 1090551 | 13390 | -0.011 | 0.1443 | No | ||
117 | AVPR1A | 2120300 | 13659 | -0.013 | 0.1305 | No | ||
118 | CCL25 | 450541 540435 | 13809 | -0.014 | 0.1232 | No | ||
119 | GCG | 6220735 | 13940 | -0.016 | 0.1169 | No | ||
120 | PIK3CA | 6220129 | 13948 | -0.016 | 0.1174 | No | ||
121 | ADCYAP1 | 520086 | 13965 | -0.016 | 0.1174 | No | ||
122 | PLCB2 | 360132 | 14047 | -0.017 | 0.1139 | No | ||
123 | CGB | 580273 | 14234 | -0.020 | 0.1048 | No | ||
124 | KISS1 | 1580398 | 14542 | -0.025 | 0.0895 | No | ||
125 | CXCR6 | 3190440 | 14571 | -0.026 | 0.0893 | No | ||
126 | ADRA1D | 380035 540025 | 14782 | -0.031 | 0.0796 | No | ||
127 | SSTR1 | 2630471 | 14971 | -0.036 | 0.0713 | No | ||
128 | PNOC | 1990114 | 15353 | -0.052 | 0.0533 | No | ||
129 | ADCY6 | 450364 6290670 6940286 | 15563 | -0.065 | 0.0454 | No | ||
130 | NMB | 3360735 | 15639 | -0.069 | 0.0450 | No | ||
131 | PDE4D | 2470528 6660014 | 15736 | -0.076 | 0.0437 | No | ||
132 | PTGER2 | 3170039 | 15757 | -0.078 | 0.0467 | No | ||
133 | P2RY2 | 2640180 2810128 | 15885 | -0.087 | 0.0443 | No | ||
134 | GNB1 | 2120397 | 15968 | -0.093 | 0.0448 | No | ||
135 | RAMP1 | 2320168 | 16061 | -0.101 | 0.0451 | No | ||
136 | P2RY10 | 6370039 6840204 | 16343 | -0.129 | 0.0366 | No | ||
137 | F2R | 4810180 | 16562 | -0.159 | 0.0331 | No | ||
138 | PDPK1 | 6650168 | 16837 | -0.204 | 0.0289 | No | ||
139 | PIK3CG | 5890110 | 17262 | -0.292 | 0.0212 | No | ||
140 | GNA13 | 4590102 | 17781 | -0.455 | 0.0169 | No | ||
141 | ROCK1 | 130044 | 17976 | -0.542 | 0.0346 | No |