Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$USF_C |
Enrichment Score (ES) | 0.50717854 |
Normalized Enrichment Score (NES) | 1.2441324 |
Nominal p-value | 0.05625879 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 22 | 4.554 | 0.0580 | Yes | ||
2 | PABPC4 | 1990170 6760270 5390138 | 29 | 4.133 | 0.1114 | Yes | ||
3 | TIMM10 | 610070 1450019 | 45 | 3.538 | 0.1566 | Yes | ||
4 | HMOX1 | 1740687 | 64 | 3.070 | 0.1955 | Yes | ||
5 | SH3KBP1 | 670102 2850458 7000309 | 167 | 2.200 | 0.2186 | Yes | ||
6 | ENO3 | 5270136 | 198 | 2.033 | 0.2434 | Yes | ||
7 | SDC1 | 3440471 6350408 | 321 | 1.645 | 0.2581 | Yes | ||
8 | G6PC3 | 1580487 5390253 | 349 | 1.594 | 0.2774 | Yes | ||
9 | EXOSC5 | 3370671 | 416 | 1.466 | 0.2928 | Yes | ||
10 | IPO4 | 5050619 | 487 | 1.348 | 0.3066 | Yes | ||
11 | ABCB6 | 6350138 | 509 | 1.319 | 0.3226 | Yes | ||
12 | FBL | 5130020 | 550 | 1.266 | 0.3369 | Yes | ||
13 | RPS19 | 5860066 | 558 | 1.260 | 0.3529 | Yes | ||
14 | PFDN2 | 4230156 | 657 | 1.117 | 0.3621 | Yes | ||
15 | RUSC1 | 6450093 6980575 | 689 | 1.074 | 0.3743 | Yes | ||
16 | PA2G4 | 2030463 | 771 | 1.012 | 0.3831 | Yes | ||
17 | GPD1 | 2480095 | 840 | 0.958 | 0.3919 | Yes | ||
18 | AKAP12 | 1450739 | 903 | 0.910 | 0.4003 | Yes | ||
19 | FKBP11 | 3170575 | 921 | 0.897 | 0.4111 | Yes | ||
20 | HSPE1 | 3170438 | 974 | 0.864 | 0.4195 | Yes | ||
21 | EXOSC2 | 6900471 | 1079 | 0.792 | 0.4241 | Yes | ||
22 | HYAL2 | 1500152 | 1097 | 0.780 | 0.4333 | Yes | ||
23 | NUDC | 4780025 | 1121 | 0.768 | 0.4421 | Yes | ||
24 | HERPUD1 | 7100440 | 1122 | 0.765 | 0.4520 | Yes | ||
25 | PSEN2 | 130382 | 1288 | 0.662 | 0.4517 | Yes | ||
26 | ALDH3B1 | 4210010 6940403 | 1331 | 0.638 | 0.4577 | Yes | ||
27 | PPAT | 1980019 | 1342 | 0.632 | 0.4654 | Yes | ||
28 | OPRS1 | 6130128 6290717 | 1415 | 0.598 | 0.4692 | Yes | ||
29 | EIF4B | 5390563 5270577 | 1494 | 0.564 | 0.4723 | Yes | ||
30 | ANXA6 | 2190014 | 1560 | 0.540 | 0.4758 | Yes | ||
31 | LYAR | 7000402 | 1562 | 0.539 | 0.4828 | Yes | ||
32 | PER1 | 3290315 | 1692 | 0.490 | 0.4822 | Yes | ||
33 | SLC39A7 | 5570131 | 1714 | 0.483 | 0.4873 | Yes | ||
34 | RHEBL1 | 2810576 | 1761 | 0.467 | 0.4909 | Yes | ||
35 | BCKDHA | 50189 | 1845 | 0.441 | 0.4921 | Yes | ||
36 | POLR2H | 5890242 | 1878 | 0.433 | 0.4960 | Yes | ||
37 | PSMB3 | 4280594 | 1881 | 0.433 | 0.5015 | Yes | ||
38 | GTF2H1 | 2570746 2650148 | 1894 | 0.430 | 0.5065 | Yes | ||
39 | HMGN2 | 3140091 | 2032 | 0.386 | 0.5040 | Yes | ||
40 | RPL22 | 4070070 | 2118 | 0.364 | 0.5042 | Yes | ||
41 | MYST3 | 5270500 | 2215 | 0.339 | 0.5034 | Yes | ||
42 | EIF2C2 | 770451 | 2248 | 0.331 | 0.5059 | Yes | ||
43 | BHLHB2 | 7040603 | 2302 | 0.317 | 0.5072 | Yes | ||
44 | PAICS | 610142 | 2382 | 0.296 | 0.5067 | No | ||
45 | POLR3E | 380152 | 2456 | 0.279 | 0.5064 | No | ||
46 | IPO13 | 3870088 | 2551 | 0.253 | 0.5046 | No | ||
47 | SRP72 | 3990427 | 2628 | 0.233 | 0.5035 | No | ||
48 | FHOD1 | 2680279 | 2637 | 0.230 | 0.5061 | No | ||
49 | FARP1 | 5290102 7100341 | 2750 | 0.205 | 0.5026 | No | ||
50 | AMPD2 | 630093 1170070 | 2809 | 0.195 | 0.5020 | No | ||
51 | BCL9L | 6940053 | 2850 | 0.189 | 0.5023 | No | ||
52 | GRK6 | 1500053 | 3131 | 0.148 | 0.4890 | No | ||
53 | TNFRSF21 | 6380100 | 3133 | 0.148 | 0.4909 | No | ||
54 | ARF6 | 3520026 | 3246 | 0.134 | 0.4866 | No | ||
55 | CACNA1D | 1740315 4730731 | 3293 | 0.128 | 0.4857 | No | ||
56 | UBE1 | 4150139 7050463 | 3494 | 0.109 | 0.4763 | No | ||
57 | MYOHD1 | 1410520 | 3640 | 0.098 | 0.4697 | No | ||
58 | CNNM1 | 2190433 | 3658 | 0.096 | 0.4700 | No | ||
59 | LTBR | 2450341 | 3666 | 0.095 | 0.4709 | No | ||
60 | MPP3 | 1400056 4480411 6770168 | 3903 | 0.081 | 0.4591 | No | ||
61 | NR1D1 | 2360471 770746 6590204 | 3969 | 0.078 | 0.4566 | No | ||
62 | SYT3 | 6380017 | 4082 | 0.072 | 0.4515 | No | ||
63 | SUCLG2 | 5340397 5700270 | 4117 | 0.071 | 0.4506 | No | ||
64 | UBXD3 | 5050193 | 4220 | 0.066 | 0.4459 | No | ||
65 | AVP | 2100113 | 4224 | 0.066 | 0.4466 | No | ||
66 | SOCS5 | 3830398 7100093 | 4232 | 0.065 | 0.4470 | No | ||
67 | TIMM9 | 2450484 | 4272 | 0.064 | 0.4458 | No | ||
68 | ETV4 | 2450605 | 4373 | 0.059 | 0.4411 | No | ||
69 | B4GALT2 | 780037 | 4396 | 0.058 | 0.4407 | No | ||
70 | CTSF | 6100021 | 4548 | 0.054 | 0.4332 | No | ||
71 | MNT | 4920575 | 4693 | 0.049 | 0.4260 | No | ||
72 | RUNX2 | 1400193 4230215 | 4938 | 0.042 | 0.4133 | No | ||
73 | HOXA3 | 3610632 6020358 | 4940 | 0.042 | 0.4138 | No | ||
74 | HPCAL4 | 2600484 | 5352 | 0.034 | 0.3920 | No | ||
75 | TBX4 | 3060008 | 5407 | 0.033 | 0.3895 | No | ||
76 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.3878 | No | ||
77 | SLC26A2 | 2360278 | 5483 | 0.032 | 0.3863 | No | ||
78 | DNMT3A | 4050068 4810717 | 5501 | 0.031 | 0.3858 | No | ||
79 | NXPH1 | 3870546 | 5525 | 0.031 | 0.3849 | No | ||
80 | BMP2K | 60541 5570504 | 5739 | 0.027 | 0.3737 | No | ||
81 | ETV1 | 70735 2940603 5080463 | 6177 | 0.022 | 0.3503 | No | ||
82 | DNAJB9 | 460114 | 6538 | 0.018 | 0.3310 | No | ||
83 | RPL13A | 2680519 5700142 | 6623 | 0.018 | 0.3267 | No | ||
84 | GRIN2A | 6550538 | 6663 | 0.017 | 0.3248 | No | ||
85 | SLC6A15 | 5290176 6040017 | 6847 | 0.016 | 0.3150 | No | ||
86 | CGN | 5890139 6370167 6400537 | 7066 | 0.014 | 0.3034 | No | ||
87 | NLN | 1450576 5870575 | 7082 | 0.014 | 0.3028 | No | ||
88 | LAP3 | 2570064 | 7137 | 0.014 | 0.3000 | No | ||
89 | HS3ST3A1 | 2230497 | 7327 | 0.013 | 0.2899 | No | ||
90 | ARRDC3 | 4610390 | 7551 | 0.011 | 0.2780 | No | ||
91 | ADAMTS17 | 6510739 | 7754 | 0.010 | 0.2671 | No | ||
92 | STMN1 | 1990717 | 7825 | 0.010 | 0.2635 | No | ||
93 | TLL1 | 2680315 | 8101 | 0.009 | 0.2487 | No | ||
94 | POGK | 5290315 | 8410 | 0.008 | 0.2321 | No | ||
95 | DRD1 | 430025 | 8411 | 0.008 | 0.2322 | No | ||
96 | FADS3 | 3120079 | 8682 | 0.007 | 0.2176 | No | ||
97 | NKX2-3 | 1990736 6940088 | 8784 | 0.006 | 0.2122 | No | ||
98 | COL2A1 | 460446 3940500 | 8812 | 0.006 | 0.2108 | No | ||
99 | CHST11 | 6760546 | 9002 | 0.005 | 0.2006 | No | ||
100 | SC5DL | 6650390 | 9089 | 0.005 | 0.1960 | No | ||
101 | SLC12A5 | 1980692 | 9505 | 0.004 | 0.1736 | No | ||
102 | HPCA | 6860010 | 9522 | 0.004 | 0.1728 | No | ||
103 | MTHFD1 | 5900398 6520427 | 9709 | 0.003 | 0.1627 | No | ||
104 | SYT6 | 2510280 3850128 4540064 | 9730 | 0.003 | 0.1617 | No | ||
105 | FLT3 | 2640487 | 9850 | 0.003 | 0.1552 | No | ||
106 | PAX6 | 1190025 | 9898 | 0.003 | 0.1527 | No | ||
107 | GPRC5C | 1580372 | 9902 | 0.003 | 0.1526 | No | ||
108 | BMP4 | 380113 | 9940 | 0.003 | 0.1506 | No | ||
109 | KIAA0427 | 1690435 | 10031 | 0.003 | 0.1458 | No | ||
110 | ABCA1 | 6290156 | 10074 | 0.002 | 0.1435 | No | ||
111 | ARX | 6900504 | 10218 | 0.002 | 0.1358 | No | ||
112 | CHRM1 | 4280619 | 10311 | 0.002 | 0.1308 | No | ||
113 | PRKCE | 5700053 | 10501 | 0.001 | 0.1206 | No | ||
114 | HOXC12 | 5270411 | 10558 | 0.001 | 0.1176 | No | ||
115 | FGF11 | 840292 | 10594 | 0.001 | 0.1157 | No | ||
116 | LIN28 | 6590672 | 10871 | 0.000 | 0.1007 | No | ||
117 | SATB2 | 2470181 | 10987 | -0.000 | 0.0945 | No | ||
118 | SGTB | 460170 | 11307 | -0.001 | 0.0772 | No | ||
119 | EIF3S1 | 6130368 6770044 | 11330 | -0.001 | 0.0760 | No | ||
120 | FGF14 | 2630390 3520075 6770048 | 11417 | -0.001 | 0.0714 | No | ||
121 | HOXC13 | 4070722 | 11552 | -0.002 | 0.0641 | No | ||
122 | NPTX1 | 3710736 | 11851 | -0.003 | 0.0480 | No | ||
123 | NPM1 | 4730427 | 12090 | -0.004 | 0.0351 | No | ||
124 | LHX9 | 2350112 | 12243 | -0.004 | 0.0269 | No | ||
125 | PLA2G4A | 6380364 | 12253 | -0.004 | 0.0265 | No | ||
126 | HHIP | 6940438 | 12396 | -0.005 | 0.0189 | No | ||
127 | PIGW | 4810072 | 12490 | -0.005 | 0.0139 | No | ||
128 | SET | 6650286 | 12669 | -0.006 | 0.0043 | No | ||
129 | SCFD2 | 2480504 | 12697 | -0.006 | 0.0029 | No | ||
130 | ELOVL4 | 5220333 | 13092 | -0.009 | -0.0183 | No | ||
131 | ENPP6 | 110524 580563 | 13105 | -0.009 | -0.0189 | No | ||
132 | MCM8 | 6130743 | 13113 | -0.009 | -0.0191 | No | ||
133 | GTF2A1 | 4120138 4920524 5390110 1230397 | 13274 | -0.010 | -0.0277 | No | ||
134 | SNCAIP | 4010551 | 13539 | -0.013 | -0.0418 | No | ||
135 | PPARGC1B | 3290114 | 13767 | -0.015 | -0.0540 | No | ||
136 | DAZL | 4050082 | 13800 | -0.016 | -0.0555 | No | ||
137 | TDRD1 | 4230301 6110750 | 13963 | -0.018 | -0.0640 | No | ||
138 | SNX5 | 1570021 6860609 | 14121 | -0.021 | -0.0723 | No | ||
139 | XRN2 | 130603 1230113 4230309 | 14153 | -0.021 | -0.0737 | No | ||
140 | LRP8 | 3610746 5360035 | 14160 | -0.022 | -0.0737 | No | ||
141 | GPX1 | 4150093 | 14266 | -0.024 | -0.0791 | No | ||
142 | ADCY3 | 2350347 3440242 | 14429 | -0.029 | -0.0875 | No | ||
143 | CDC14A | 4050132 | 14547 | -0.033 | -0.0934 | No | ||
144 | WEE1 | 3390070 | 14710 | -0.041 | -0.1017 | No | ||
145 | HOXA4 | 940152 | 15064 | -0.062 | -0.1200 | No | ||
146 | EEF1E1 | 4540711 | 15217 | -0.073 | -0.1273 | No | ||
147 | SEMA7A | 2630239 5050593 | 15256 | -0.075 | -0.1284 | No | ||
148 | DAZAP1 | 5890563 | 15260 | -0.076 | -0.1276 | No | ||
149 | HSPA4 | 1050170 3450309 | 15362 | -0.087 | -0.1320 | No | ||
150 | CAMK4 | 1690091 | 15490 | -0.100 | -0.1375 | No | ||
151 | EIF4E | 1580403 70133 6380215 | 15566 | -0.108 | -0.1402 | No | ||
152 | SLC31A2 | 1450577 | 15598 | -0.111 | -0.1404 | No | ||
153 | CRMP1 | 4810014 | 15780 | -0.132 | -0.1486 | No | ||
154 | CENTB5 | 5690128 | 15836 | -0.139 | -0.1497 | No | ||
155 | EIF5A | 1500059 5290022 6370026 | 15867 | -0.144 | -0.1495 | No | ||
156 | CNOT4 | 2320242 6760706 | 15894 | -0.148 | -0.1490 | No | ||
157 | RPL19 | 5550592 | 15897 | -0.148 | -0.1472 | No | ||
158 | CLCN2 | 1940021 | 15981 | -0.161 | -0.1496 | No | ||
159 | PFN1 | 6130132 | 15998 | -0.164 | -0.1483 | No | ||
160 | EFNB1 | 2970433 | 16084 | -0.175 | -0.1507 | No | ||
161 | USP2 | 1190292 1240253 4850035 | 16094 | -0.176 | -0.1489 | No | ||
162 | EIF4G1 | 4070446 | 16118 | -0.180 | -0.1478 | No | ||
163 | IVNS1ABP | 4760601 6520113 | 16269 | -0.211 | -0.1531 | No | ||
164 | SIRT1 | 1190731 | 16288 | -0.214 | -0.1513 | No | ||
165 | PDK2 | 2690017 | 16619 | -0.299 | -0.1654 | No | ||
166 | MAX | 5220021 | 16704 | -0.322 | -0.1657 | No | ||
167 | MXD4 | 4810113 | 16889 | -0.375 | -0.1708 | No | ||
168 | MORF4L2 | 6450133 | 17074 | -0.438 | -0.1751 | No | ||
169 | MAT2A | 4070026 4730079 6020280 | 17099 | -0.450 | -0.1706 | No | ||
170 | ACVR2B | 1660546 | 17449 | -0.606 | -0.1817 | No | ||
171 | SLC20A1 | 6420014 | 17461 | -0.615 | -0.1743 | No | ||
172 | RXRB | 1780040 5340438 | 17500 | -0.629 | -0.1681 | No | ||
173 | HSPH1 | 1690017 | 17547 | -0.655 | -0.1621 | No | ||
174 | GABARAP | 1450286 | 17563 | -0.667 | -0.1543 | No | ||
175 | DIABLO | 2360170 | 17610 | -0.690 | -0.1478 | No | ||
176 | PTMA | 5570148 | 17633 | -0.699 | -0.1399 | No | ||
177 | GNA13 | 4590102 | 17647 | -0.709 | -0.1314 | No | ||
178 | H3F3A | 2900086 | 17766 | -0.783 | -0.1276 | No | ||
179 | BCAS3 | 4050647 | 17787 | -0.795 | -0.1184 | No | ||
180 | TEF | 1050050 3120397 4060487 | 17981 | -0.960 | -0.1163 | No | ||
181 | WBP2 | 3170128 | 18131 | -1.163 | -0.1093 | No | ||
182 | PPP1R9B | 3130619 | 18136 | -1.173 | -0.0943 | No | ||
183 | FCHSD2 | 5720092 | 18137 | -1.173 | -0.0790 | No | ||
184 | HSPBAP1 | 4060022 | 18320 | -1.547 | -0.0688 | No | ||
185 | RORC | 1740121 | 18527 | -2.412 | -0.0486 | No | ||
186 | BCL6 | 940100 | 18610 | -4.108 | 0.0003 | No |