Details for gene set V$NRF2

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos
Phenotype	phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in class	truncNotch
GeneSet	V$NRF2_Q4
Enrichment Score (ES)	0.49496654
Normalized Enrichment Score (NES)	1.2184085
Nominal p-value	0.083333336
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ITM2B	1850482 5860671 6200014	6	5.597	0.0860	Yes
2	SLC11A1	940286 2810435 6370647	54	3.339	0.1349	Yes
3	ENO1	5340128	161	2.215	0.1633	Yes
4	ELA1	3390167	189	2.067	0.1937	Yes
5	NDRG2	450403	220	1.946	0.2221	Yes
6	ETV5	110017	222	1.935	0.2518	Yes
7	ALDOA	6290672	242	1.875	0.2797	Yes
8	ARHGAP8	380333 5390487	337	1.608	0.2994	Yes
9	CSNK1G2	3060095 4730037	366	1.564	0.3220	Yes
10	HSPG2	2510687 6220750	367	1.563	0.3461	Yes
11	SYTL1	510487	475	1.360	0.3613	Yes
12	ABCB6	6350138	509	1.319	0.3798	Yes
13	EPHB2	1090288 1410377 2100541	602	1.194	0.3932	Yes
14	PKN3	2260538	717	1.052	0.4032	Yes
15	SLC38A2	1470242 3800026	730	1.045	0.4187	Yes
16	ADAM15	5890707	758	1.026	0.4330	Yes
17	BAG2	2900324	851	0.951	0.4427	Yes
18	DTX2	4210041 7000008	885	0.928	0.4552	Yes
19	ABCA2	5050039	1162	0.745	0.4518	Yes
20	LIMK1	5080064	1220	0.704	0.4595	Yes
21	DCTN2	540471 3780717	1241	0.694	0.4691	Yes
22	ALS2	3130546 6400070	1389	0.612	0.4706	Yes
23	RBBP7	430113 450450 2370309	1647	0.507	0.4645	Yes
24	PSMC5	2760315 6550021	1675	0.497	0.4707	Yes
25	PSMD2	4670706 5050364	1687	0.492	0.4777	Yes
26	BLMH	1410438	1742	0.474	0.4820	Yes
27	ADCK4	1660180	1784	0.459	0.4869	Yes
28	BLVRB	7040707	1958	0.412	0.4839	Yes
29	LMO4	3800746	2000	0.395	0.4877	Yes
30	LRP1	6270386	2060	0.378	0.4904	Yes
31	TBXAS1	5050053 6900286	2082	0.373	0.4950	Yes
32	ABHD4	6760450	2421	0.287	0.4811	No
33	UBE2L3	1690707 5900242	2550	0.253	0.4780	No
34	IPO13	3870088	2551	0.253	0.4819	No
35	NR5A1	70707	2556	0.251	0.4856	No
36	SKP1A	2450102	2641	0.230	0.4846	No
37	XPOT	7050184	2747	0.206	0.4820	No
38	MMP19	5080377	2811	0.195	0.4816	No
39	BCL9L	6940053	2850	0.189	0.4825	No
40	PSME4	380348 1770131	3145	0.146	0.4688	No
41	PSMD12	730044	3274	0.130	0.4638	No
42	GADD45G	2510142	3283	0.130	0.4654	No
43	FTSJ3	3140100	3490	0.109	0.4559	No
44	DUSP13	6400152	3645	0.098	0.4491	No
45	ROM1	3130685	3782	0.088	0.4431	No
46	PFN2	730040 5700026	3882	0.082	0.4389	No
47	NR1D1	2360471 770746 6590204	3969	0.078	0.4355	No
48	NOTCH4	2450040 6370707	3994	0.077	0.4354	No
49	CDH23	4250242 5290397 6550397	4195	0.067	0.4255	No
50	TOMM70A	780114	4219	0.066	0.4253	No
51	PRX	2260400 4200347	4300	0.062	0.4219	No
52	CNTN6	2630711	4491	0.056	0.4125	No
53	DRP2	4560110	4524	0.054	0.4116	No
54	MDFI	6200041	4610	0.052	0.4078	No
55	MNT	4920575	4693	0.049	0.4041	No
56	GAS2L1	3190138	4785	0.047	0.3999	No
57	FLNC	2360048 5050270	4791	0.046	0.4003	No
58	INHA	6100102	4882	0.044	0.3961	No
59	HOXA3	3610632 6020358	4940	0.042	0.3937	No
60	OGG1	1940279	5045	0.040	0.3887	No
61	PLEC1	6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471	5220	0.037	0.3798	No
62	TIAL1	4150048 6510605	5446	0.032	0.3681	No
63	CANX	4760402	5561	0.030	0.3624	No
64	FGF9	1050195	5564	0.030	0.3627	No
65	FCHSD1	5080050 6450025	5659	0.029	0.3581	No
66	MMRN2	1740047	5683	0.029	0.3573	No
67	RB1CC1	510494 7100072	5691	0.028	0.3573	No
68	EEF1A2	2260162 5290086	5826	0.026	0.3505	No
69	FOXN1	4730075	5876	0.025	0.3482	No
70	GPR21	6520152	5952	0.024	0.3445	No
71	SLC16A6	1690156	6017	0.023	0.3414	No
72	F2RL2	6110736	6030	0.023	0.3411	No
73	ZIC1	670113	6083	0.023	0.3386	No
74	RDH5	2970736 3940632 5340730 6370093 4610059	6135	0.022	0.3362	No
75	APBA2BP	5700341	6248	0.021	0.3304	No
76	MIA2	3130181	6279	0.020	0.3291	No
77	KCND1	6860278	6653	0.017	0.3092	No
78	CD44	3990072 4850671 5860411 6860148 7050551	7174	0.013	0.2812	No
79	MAPRE3	7050504	7209	0.013	0.2795	No
80	CLDN15	4150270 4730592	7222	0.013	0.2791	No
81	BTK	3130044	7290	0.013	0.2756	No
82	LRP1B	1450193	7555	0.011	0.2615	No
83	PSMA2	6510093	7602	0.011	0.2592	No
84	ADCYAP1	520086	7643	0.011	0.2572	No
85	PHLDA2	4810494	7658	0.011	0.2566	No
86	UBXD2	4280092	7688	0.011	0.2552	No
87	ESRRG	4010181	7822	0.010	0.2481	No
88	MASP1	1780619 2900066	8010	0.009	0.2381	No
89	TLL1	2680315	8101	0.009	0.2334	No
90	PAFAH1B1	4230333 6420121 6450066	8128	0.009	0.2321	No
91	MYH14	4010017	8227	0.008	0.2269	No
92	LGI3	5910301	8491	0.007	0.2128	No
93	CPNE8	7040039	8836	0.006	0.1942	No
94	TFPI2	3870324	8837	0.006	0.1943	No
95	APBA1	3140487	8844	0.006	0.1941	No
96	TREX1	3450040 7100692	9165	0.005	0.1768	No
97	TNXB	630592 3830020 5360497 7000673	9296	0.005	0.1698	No
98	NOG	2320609	9311	0.005	0.1691	No
99	SMPX	6590440	9333	0.005	0.1680	No
100	RAN	2260446 4590647	9367	0.004	0.1663	No
101	SMAD6	870504	9733	0.003	0.1466	No
102	RHOH	130184	9739	0.003	0.1464	No
103	DMD	1740041 3990332	10112	0.002	0.1262	No
104	BNIP3	3140270	10327	0.002	0.1146	No
105	SOST	1170195	10394	0.002	0.1111	No
106	CRYBA2	5900138	10466	0.001	0.1073	No
107	FGF11	840292	10594	0.001	0.1004	No
108	CAPN6	1740168	11167	-0.001	0.0694	No
109	USP13	1450670	11261	-0.001	0.0643	No
110	SYT2	60609	11396	-0.001	0.0571	No
111	RGS2	1090736	11767	-0.003	0.0371	No
112	PRDM1	3170347 3520301	11775	-0.003	0.0367	No
113	EDG1	4200619	11785	-0.003	0.0363	No
114	CRYGS	2680398	11955	-0.003	0.0272	No
115	NUDT11	3840239	11986	-0.003	0.0256	No
116	FGF12	1740446 2360037	12167	-0.004	0.0159	No
117	WNT2	4610020	12190	-0.004	0.0148	No
118	SH3BGRL2	1780239	12255	-0.004	0.0114	No
119	CSMD3	1660427 1940687	12332	-0.005	0.0073	No
120	TFEC	1170722	12346	-0.005	0.0067	No
121	LOXL4	6520095	12599	-0.006	-0.0069	No
122	SLC26A1	2190142	12607	-0.006	-0.0072	No
123	FGF1	4780435 5670601	12638	-0.006	-0.0087	No
124	GDF8	3850504	12813	-0.007	-0.0180	No
125	MCF2	4780133	12884	-0.007	-0.0217	No
126	SFXN5	2630152	12925	-0.008	-0.0238	No
127	RARG	6760136	13031	-0.008	-0.0293	No
128	GTF2A1	4120138 4920524 5390110 1230397	13274	-0.010	-0.0423	No
129	IDS	360619 5720161	13329	-0.011	-0.0451	No
130	IL6	380133	13456	-0.012	-0.0517	No
131	SPTBN4	4150279 5270286	13549	-0.013	-0.0565	No
132	MRPL32	110041	13674	-0.014	-0.0630	No
133	PDE4D	2470528 6660014	13911	-0.017	-0.0755	No
134	SNCG	3120725	14021	-0.019	-0.0812	No
135	RABEP1	4760427 6200463	14076	-0.020	-0.0838	No
136	KCNA2	5080403	14158	-0.022	-0.0878	No
137	LRRFIP2	670575 730152 6590438	14179	-0.022	-0.0886	No
138	KIF5A	510435	14512	-0.032	-0.1061	No
139	ITPKC	5420021	15077	-0.063	-0.1357	No
140	ABCD1	5670373	15194	-0.071	-0.1409	No
141	CACNB2	1500095 7330707	15206	-0.072	-0.1404	No
142	MGST1	6020605	15323	-0.083	-0.1454	No
143	TUBB	730670 3390037	15465	-0.096	-0.1516	No
144	MAP2K1	840739	15475	-0.098	-0.1506	No
145	ATP6V0A1	1570082 3870441 4230044	15520	-0.103	-0.1514	No
146	USP14	730377 4050333	15525	-0.103	-0.1500	No
147	RAB6A	3840463 4780731	15543	-0.105	-0.1493	No
148	LAMA3	1190131 5290239	15581	-0.109	-0.1496	No
149	TXNRD1	6590446	15628	-0.115	-0.1504	No
150	WBP4	2230019	15725	-0.126	-0.1536	No
151	AKT3	1580270 3290278	15756	-0.129	-0.1533	No
152	SQSTM1	6550056	15821	-0.137	-0.1546	No
153	PITPNC1	3990017	15889	-0.147	-0.1560	No
154	ZIC4	1500082	15904	-0.148	-0.1545	No
155	UCHL1	1230066	16091	-0.176	-0.1618	No
156	EIF4G1	4070446	16118	-0.180	-0.1605	No
157	CAPN12	2100050	16282	-0.212	-0.1660	No
158	PER2	3120204 3390593	16397	-0.236	-0.1686	No
159	SEC24D	3060279	16584	-0.285	-0.1743	No
160	PSMD4	430068	16588	-0.287	-0.1700	No
161	PIAS1	5340301	16608	-0.296	-0.1665	No
162	GPX2	6940619	16612	-0.297	-0.1620	No
163	BACH1	290195	16764	-0.337	-0.1650	No
164	TBL1X	6400524	16897	-0.379	-0.1664	No
165	PSMD7	2030619 6220594	16931	-0.389	-0.1622	No
166	YWHAG	3780341	16937	-0.391	-0.1564	No
167	TTC1	5890736	16948	-0.395	-0.1509	No
168	BAZ2A	730184	17111	-0.455	-0.1526	No
169	VCP	5340168	17192	-0.488	-0.1494	No
170	MAST2	6200348	17406	-0.581	-0.1520	No
171	KCNH3	3130100	17901	-0.894	-0.1651	No
172	H3F3B	1410300	18062	-1.050	-0.1575	No
173	PPP1R9B	3130619	18136	-1.173	-0.1434	No
174	LAMC1	4730025	18218	-1.300	-0.1278	No
175	BEX2	5670433	18254	-1.372	-0.1085	No
176	ATP1B1	3130594	18366	-1.702	-0.0883	No
177	BRD2	1450300 5340484 6100605	18440	-1.886	-0.0632	No
178	PSMA3	5900047 7040161	18612	-4.714	0.0002	No