Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$NMYC_01 |
Enrichment Score (ES) | 0.5592185 |
Normalized Enrichment Score (NES) | 1.3668886 |
Nominal p-value | 0.008784773 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 22 | 4.554 | 0.0706 | Yes | ||
2 | PABPC4 | 1990170 6760270 5390138 | 29 | 4.133 | 0.1354 | Yes | ||
3 | TIMM10 | 610070 1450019 | 45 | 3.538 | 0.1903 | Yes | ||
4 | HMOX1 | 1740687 | 64 | 3.070 | 0.2377 | Yes | ||
5 | SH3KBP1 | 670102 2850458 7000309 | 167 | 2.200 | 0.2668 | Yes | ||
6 | CEBPB | 2970019 | 183 | 2.087 | 0.2989 | Yes | ||
7 | VARS2 | 1410017 3800114 4210270 | 265 | 1.789 | 0.3227 | Yes | ||
8 | G6PC3 | 1580487 5390253 | 349 | 1.594 | 0.3433 | Yes | ||
9 | IPO4 | 5050619 | 487 | 1.348 | 0.3571 | Yes | ||
10 | ATAD3A | 4050288 | 489 | 1.342 | 0.3782 | Yes | ||
11 | FBL | 5130020 | 550 | 1.266 | 0.3949 | Yes | ||
12 | BCL7C | 460050 | 578 | 1.234 | 0.4129 | Yes | ||
13 | DUSP4 | 2690044 2850593 | 625 | 1.163 | 0.4287 | Yes | ||
14 | PA2G4 | 2030463 | 771 | 1.012 | 0.4368 | Yes | ||
15 | ATP5G1 | 5290019 | 777 | 1.007 | 0.4524 | Yes | ||
16 | GPD1 | 2480095 | 840 | 0.958 | 0.4642 | Yes | ||
17 | HSPE1 | 3170438 | 974 | 0.864 | 0.4706 | Yes | ||
18 | COPS7A | 3940458 7000022 | 989 | 0.858 | 0.4833 | Yes | ||
19 | PRDX4 | 3800039 | 1047 | 0.818 | 0.4931 | Yes | ||
20 | VPS16 | 430064 3390041 6860301 | 1076 | 0.794 | 0.5041 | Yes | ||
21 | HYAL2 | 1500152 | 1097 | 0.780 | 0.5153 | Yes | ||
22 | PSEN2 | 130382 | 1288 | 0.662 | 0.5154 | Yes | ||
23 | PPAT | 1980019 | 1342 | 0.632 | 0.5225 | Yes | ||
24 | EIF4B | 5390563 5270577 | 1494 | 0.564 | 0.5232 | Yes | ||
25 | ANXA6 | 2190014 | 1560 | 0.540 | 0.5282 | Yes | ||
26 | NOL5A | 5570139 | 1787 | 0.459 | 0.5232 | Yes | ||
27 | GTPBP1 | 2230541 4560528 | 1846 | 0.441 | 0.5270 | Yes | ||
28 | DLX1 | 360168 | 1962 | 0.410 | 0.5272 | Yes | ||
29 | FKBP5 | 2190048 | 1981 | 0.401 | 0.5326 | Yes | ||
30 | HMGN2 | 3140091 | 2032 | 0.386 | 0.5359 | Yes | ||
31 | RPL22 | 4070070 | 2118 | 0.364 | 0.5371 | Yes | ||
32 | FKBP10 | 1340706 | 2135 | 0.358 | 0.5418 | Yes | ||
33 | LMNB1 | 5890292 6020008 | 2211 | 0.341 | 0.5431 | Yes | ||
34 | MYST3 | 5270500 | 2215 | 0.339 | 0.5483 | Yes | ||
35 | TLE3 | 580040 4730121 | 2450 | 0.280 | 0.5400 | Yes | ||
36 | POLR3E | 380152 | 2456 | 0.279 | 0.5442 | Yes | ||
37 | HSPD1 | 60097 2030451 | 2475 | 0.272 | 0.5475 | Yes | ||
38 | PES1 | 2470427 | 2548 | 0.253 | 0.5475 | Yes | ||
39 | IPO13 | 3870088 | 2551 | 0.253 | 0.5514 | Yes | ||
40 | NR5A1 | 70707 | 2556 | 0.251 | 0.5552 | Yes | ||
41 | SRP72 | 3990427 | 2628 | 0.233 | 0.5550 | Yes | ||
42 | FHOD1 | 2680279 | 2637 | 0.230 | 0.5582 | Yes | ||
43 | ATP6V0B | 2810112 | 2683 | 0.221 | 0.5592 | Yes | ||
44 | AMPD2 | 630093 1170070 | 2809 | 0.195 | 0.5555 | No | ||
45 | KRTCAP2 | 5220040 | 2965 | 0.171 | 0.5498 | No | ||
46 | GRK6 | 1500053 | 3131 | 0.148 | 0.5432 | No | ||
47 | ARF6 | 3520026 | 3246 | 0.134 | 0.5391 | No | ||
48 | GADD45G | 2510142 | 3283 | 0.130 | 0.5392 | No | ||
49 | CACNA1D | 1740315 4730731 | 3293 | 0.128 | 0.5407 | No | ||
50 | UBE1 | 4150139 7050463 | 3494 | 0.109 | 0.5316 | No | ||
51 | SCYL1 | 5050717 | 3507 | 0.108 | 0.5326 | No | ||
52 | AKAP10 | 2630504 5910577 | 3649 | 0.097 | 0.5265 | No | ||
53 | TPM2 | 520735 3870390 | 3768 | 0.089 | 0.5215 | No | ||
54 | NR1D1 | 2360471 770746 6590204 | 3969 | 0.078 | 0.5119 | No | ||
55 | BARHL1 | 4210113 | 4104 | 0.071 | 0.5058 | No | ||
56 | SLC38A5 | 540093 | 4214 | 0.066 | 0.5009 | No | ||
57 | DLC1 | 1090632 6450594 | 4227 | 0.066 | 0.5013 | No | ||
58 | SOCS5 | 3830398 7100093 | 4232 | 0.065 | 0.5021 | No | ||
59 | ELOVL6 | 5340746 | 4236 | 0.065 | 0.5030 | No | ||
60 | LIG3 | 2940300 | 4266 | 0.064 | 0.5024 | No | ||
61 | TIMM9 | 2450484 | 4272 | 0.064 | 0.5031 | No | ||
62 | B4GALT2 | 780037 | 4396 | 0.058 | 0.4974 | No | ||
63 | NRAS | 6900577 | 4430 | 0.057 | 0.4965 | No | ||
64 | RNF128 | 1230300 5670273 | 4503 | 0.055 | 0.4934 | No | ||
65 | CTSF | 6100021 | 4548 | 0.054 | 0.4919 | No | ||
66 | BAI2 | 380632 630113 6650170 | 4651 | 0.051 | 0.4872 | No | ||
67 | MNT | 4920575 | 4693 | 0.049 | 0.4857 | No | ||
68 | RAD9A | 110300 1940632 3990390 6040014 | 4765 | 0.047 | 0.4826 | No | ||
69 | TESK2 | 6520524 | 4797 | 0.046 | 0.4817 | No | ||
70 | RUNX2 | 1400193 4230215 | 4938 | 0.042 | 0.4748 | No | ||
71 | KCNK5 | 4590504 6860687 | 5228 | 0.036 | 0.4596 | No | ||
72 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.4484 | No | ||
73 | ADPRHL1 | 4150133 6650300 | 5471 | 0.032 | 0.4476 | No | ||
74 | MAPKAPK3 | 630520 | 5500 | 0.031 | 0.4466 | No | ||
75 | DNMT3A | 4050068 4810717 | 5501 | 0.031 | 0.4471 | No | ||
76 | NXPH1 | 3870546 | 5525 | 0.031 | 0.4463 | No | ||
77 | BMP2K | 60541 5570504 | 5739 | 0.027 | 0.4352 | No | ||
78 | PLAGL1 | 3190082 6200193 | 6141 | 0.022 | 0.4138 | No | ||
79 | ETV1 | 70735 2940603 5080463 | 6177 | 0.022 | 0.4122 | No | ||
80 | RTN4RL2 | 6450609 | 6534 | 0.018 | 0.3932 | No | ||
81 | DNAJB9 | 460114 | 6538 | 0.018 | 0.3933 | No | ||
82 | GPC3 | 6180735 | 6598 | 0.018 | 0.3904 | No | ||
83 | RPL13A | 2680519 5700142 | 6623 | 0.018 | 0.3894 | No | ||
84 | GRIN2A | 6550538 | 6663 | 0.017 | 0.3875 | No | ||
85 | SFXN2 | 2650563 3140095 3830762 3870398 | 6892 | 0.016 | 0.3754 | No | ||
86 | SOX12 | 1780037 | 6988 | 0.015 | 0.3705 | No | ||
87 | LAP3 | 2570064 | 7137 | 0.014 | 0.3627 | No | ||
88 | HS3ST3A1 | 2230497 | 7327 | 0.013 | 0.3526 | No | ||
89 | ARRDC3 | 4610390 | 7551 | 0.011 | 0.3407 | No | ||
90 | NKX2-2 | 4150731 | 7557 | 0.011 | 0.3406 | No | ||
91 | ADAMTS17 | 6510739 | 7754 | 0.010 | 0.3302 | No | ||
92 | GPS1 | 2470037 4760315 6200528 7100040 | 7803 | 0.010 | 0.3277 | No | ||
93 | CTBP2 | 430309 3710079 | 7928 | 0.010 | 0.3211 | No | ||
94 | NEUROD2 | 5290097 | 8306 | 0.008 | 0.3008 | No | ||
95 | POGK | 5290315 | 8410 | 0.008 | 0.2954 | No | ||
96 | NRXN1 | 460408 5340270 6370066 | 8425 | 0.008 | 0.2947 | No | ||
97 | JPH1 | 610739 | 8475 | 0.007 | 0.2922 | No | ||
98 | PCDHA10 | 3830725 | 8522 | 0.007 | 0.2898 | No | ||
99 | COL2A1 | 460446 3940500 | 8812 | 0.006 | 0.2742 | No | ||
100 | ANGPT2 | 1230458 5720706 6040605 | 8928 | 0.006 | 0.2681 | No | ||
101 | CHST11 | 6760546 | 9002 | 0.005 | 0.2642 | No | ||
102 | SC5DL | 6650390 | 9089 | 0.005 | 0.2596 | No | ||
103 | CUGBP1 | 450292 510022 7050176 7050215 | 9112 | 0.005 | 0.2585 | No | ||
104 | SLC12A5 | 1980692 | 9505 | 0.004 | 0.2373 | No | ||
105 | ADAM10 | 3780156 | 9517 | 0.004 | 0.2368 | No | ||
106 | HPCA | 6860010 | 9522 | 0.004 | 0.2366 | No | ||
107 | MTHFD1 | 5900398 6520427 | 9709 | 0.003 | 0.2266 | No | ||
108 | FLT3 | 2640487 | 9850 | 0.003 | 0.2190 | No | ||
109 | HOXB7 | 4540706 4610358 | 9975 | 0.003 | 0.2124 | No | ||
110 | KIAA0427 | 1690435 | 10031 | 0.003 | 0.2094 | No | ||
111 | ABCA1 | 6290156 | 10074 | 0.002 | 0.2072 | No | ||
112 | CHRM1 | 4280619 | 10311 | 0.002 | 0.1944 | No | ||
113 | PRKCE | 5700053 | 10501 | 0.001 | 0.1842 | No | ||
114 | RCL1 | 1980408 2680008 3800176 | 10519 | 0.001 | 0.1833 | No | ||
115 | FGF11 | 840292 | 10594 | 0.001 | 0.1793 | No | ||
116 | SEPT3 | 3830022 5290079 | 10725 | 0.001 | 0.1722 | No | ||
117 | NEUROD6 | 4670731 | 10794 | 0.000 | 0.1685 | No | ||
118 | ALX4 | 3870019 | 10815 | 0.000 | 0.1675 | No | ||
119 | LIN28 | 6590672 | 10871 | 0.000 | 0.1645 | No | ||
120 | B3GALT2 | 430136 | 11264 | -0.001 | 0.1432 | No | ||
121 | SGTB | 460170 | 11307 | -0.001 | 0.1410 | No | ||
122 | EIF3S1 | 6130368 6770044 | 11330 | -0.001 | 0.1398 | No | ||
123 | HOXC13 | 4070722 | 11552 | -0.002 | 0.1279 | No | ||
124 | SLC17A2 | 870593 2810035 | 11607 | -0.002 | 0.1250 | No | ||
125 | NPM1 | 4730427 | 12090 | -0.004 | 0.0989 | No | ||
126 | NUP153 | 7000452 | 12121 | -0.004 | 0.0973 | No | ||
127 | EN2 | 7000368 | 12196 | -0.004 | 0.0934 | No | ||
128 | LHX9 | 2350112 | 12243 | -0.004 | 0.0909 | No | ||
129 | PLA2G4A | 6380364 | 12253 | -0.004 | 0.0905 | No | ||
130 | POU3F1 | 3710022 | 12375 | -0.005 | 0.0840 | No | ||
131 | HHIP | 6940438 | 12396 | -0.005 | 0.0830 | No | ||
132 | APOA5 | 6130471 | 12494 | -0.005 | 0.0779 | No | ||
133 | SCFD2 | 2480504 | 12697 | -0.006 | 0.0670 | No | ||
134 | STMN4 | 2900091 | 12782 | -0.007 | 0.0626 | No | ||
135 | NDUFS1 | 2650253 | 12920 | -0.008 | 0.0552 | No | ||
136 | ENPP6 | 110524 580563 | 13105 | -0.009 | 0.0454 | No | ||
137 | MCM8 | 6130743 | 13113 | -0.009 | 0.0452 | No | ||
138 | SNCAIP | 4010551 | 13539 | -0.013 | 0.0223 | No | ||
139 | RBBP6 | 2320129 | 13716 | -0.015 | 0.0130 | No | ||
140 | PPARGC1B | 3290114 | 13767 | -0.015 | 0.0105 | No | ||
141 | PLAG1 | 1450142 3870139 6520039 | 13805 | -0.016 | 0.0088 | No | ||
142 | XRN2 | 130603 1230113 4230309 | 14153 | -0.021 | -0.0097 | No | ||
143 | ADCY3 | 2350347 3440242 | 14429 | -0.029 | -0.0242 | No | ||
144 | SEMA3F | 5420601 6770731 | 14473 | -0.031 | -0.0260 | No | ||
145 | CDC14A | 4050132 | 14547 | -0.033 | -0.0294 | No | ||
146 | WEE1 | 3390070 | 14710 | -0.041 | -0.0376 | No | ||
147 | TOP1 | 770471 4060632 6650324 | 14935 | -0.054 | -0.0489 | No | ||
148 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 14970 | -0.055 | -0.0499 | No | ||
149 | HRH3 | 6180040 | 15059 | -0.061 | -0.0537 | No | ||
150 | RAMP2 | 6860037 | 15205 | -0.072 | -0.0604 | No | ||
151 | SEMA7A | 2630239 5050593 | 15256 | -0.075 | -0.0619 | No | ||
152 | PANK3 | 3060687 | 15331 | -0.083 | -0.0646 | No | ||
153 | ZCCHC7 | 6510592 | 15496 | -0.100 | -0.0719 | No | ||
154 | GADD45B | 2350408 | 15818 | -0.136 | -0.0872 | No | ||
155 | CLCN2 | 1940021 | 15981 | -0.161 | -0.0934 | No | ||
156 | HRSP12 | 610136 2510133 4280561 2760047 | 15985 | -0.162 | -0.0911 | No | ||
157 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15995 | -0.163 | -0.0890 | No | ||
158 | PFN1 | 6130132 | 15998 | -0.164 | -0.0865 | No | ||
159 | USP2 | 1190292 1240253 4850035 | 16094 | -0.176 | -0.0889 | No | ||
160 | EIF4G1 | 4070446 | 16118 | -0.180 | -0.0873 | No | ||
161 | ZHX2 | 2900452 | 16244 | -0.206 | -0.0908 | No | ||
162 | PDK2 | 2690017 | 16619 | -0.299 | -0.1064 | No | ||
163 | MAX | 5220021 | 16704 | -0.322 | -0.1059 | No | ||
164 | MXD4 | 4810113 | 16889 | -0.375 | -0.1099 | No | ||
165 | PFKFB3 | 630706 | 17316 | -0.539 | -0.1246 | No | ||
166 | SLC20A1 | 6420014 | 17461 | -0.615 | -0.1227 | No | ||
167 | RXRB | 1780040 5340438 | 17500 | -0.629 | -0.1148 | No | ||
168 | HTF9C | 3190048 4120132 | 17522 | -0.642 | -0.1058 | No | ||
169 | GJA1 | 5220731 | 17586 | -0.676 | -0.0986 | No | ||
170 | GNA13 | 4590102 | 17647 | -0.709 | -0.0907 | No | ||
171 | U2AF2 | 450600 4670128 5420292 | 17707 | -0.746 | -0.0821 | No | ||
172 | TEF | 1050050 3120397 4060487 | 17981 | -0.960 | -0.0818 | No | ||
173 | RPIA | 780079 | 18022 | -1.009 | -0.0681 | No | ||
174 | STAT3 | 460040 3710341 | 18039 | -1.029 | -0.0527 | No | ||
175 | AP1GBP1 | 2510372 | 18042 | -1.031 | -0.0366 | No | ||
176 | WBP2 | 3170128 | 18131 | -1.163 | -0.0231 | No | ||
177 | RBM3 | 2360739 5700167 | 18232 | -1.334 | -0.0075 | No | ||
178 | HBP1 | 2510102 3130010 4210619 | 18407 | -1.792 | 0.0113 | No |