Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NKX61_01 |
Enrichment Score (ES) | -0.6440042 |
Normalized Enrichment Score (NES) | -1.699124 |
Nominal p-value | 0.0 |
FDR q-value | 0.008479781 |
FWER p-Value | 0.044 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | LMNA | 520471 1500075 3190167 4210020 | 152 | 2.286 | 0.0427 | No | ||
2 | SSBP3 | 870717 1050377 7040551 | 357 | 1.583 | 0.0670 | No | ||
3 | CXCL13 | 6290402 | 722 | 1.051 | 0.0707 | No | ||
4 | PRKAG1 | 6450091 | 1656 | 0.503 | 0.0314 | No | ||
5 | WNT8B | 4560301 | 1835 | 0.444 | 0.0316 | No | ||
6 | TBXAS1 | 5050053 6900286 | 2082 | 0.373 | 0.0266 | No | ||
7 | TYRO3 | 3130193 | 2193 | 0.345 | 0.0284 | No | ||
8 | SESN3 | 110687 | 2497 | 0.265 | 0.0179 | No | ||
9 | STOML2 | 1940487 | 2746 | 0.206 | 0.0090 | No | ||
10 | HESX1 | 4050746 | 3174 | 0.142 | -0.0110 | No | ||
11 | ZRANB1 | 510373 4540278 | 3245 | 0.134 | -0.0118 | No | ||
12 | NTNG2 | 1770438 6380408 | 3366 | 0.120 | -0.0156 | No | ||
13 | NR2F1 | 4120528 360402 | 3371 | 0.120 | -0.0131 | No | ||
14 | DTNA | 1340600 1780731 2340278 2850132 | 3603 | 0.100 | -0.0234 | No | ||
15 | A2BP1 | 2370390 4590593 5550014 | 3723 | 0.091 | -0.0278 | No | ||
16 | HOXC6 | 3850133 4920736 | 3792 | 0.088 | -0.0296 | No | ||
17 | MAN1C1 | 730133 870398 2340044 | 4086 | 0.072 | -0.0438 | No | ||
18 | FOXP2 | 3520561 4150372 4760524 | 4262 | 0.064 | -0.0519 | No | ||
19 | AP3M2 | 6370474 | 4294 | 0.063 | -0.0522 | No | ||
20 | PLCD4 | 6450040 | 4316 | 0.061 | -0.0519 | No | ||
21 | POU3F4 | 870274 | 4364 | 0.059 | -0.0531 | No | ||
22 | UBE2C | 6130017 | 4453 | 0.057 | -0.0566 | No | ||
23 | HSN2 | 610180 | 4506 | 0.055 | -0.0582 | No | ||
24 | GNAT2 | 2450433 | 4676 | 0.050 | -0.0663 | No | ||
25 | HOXC10 | 5360170 | 4718 | 0.049 | -0.0674 | No | ||
26 | GK2 | 6510736 | 4801 | 0.046 | -0.0708 | No | ||
27 | COL11A2 | 5130341 | 5073 | 0.040 | -0.0846 | No | ||
28 | HOXB8 | 3710450 | 5077 | 0.040 | -0.0839 | No | ||
29 | ODZ1 | 5050731 | 5278 | 0.035 | -0.0939 | No | ||
30 | DSG4 | 3990605 6400736 | 5571 | 0.030 | -0.1091 | No | ||
31 | ANXA10 | 4050750 | 5671 | 0.029 | -0.1138 | No | ||
32 | PDGFRA | 2940332 | 5734 | 0.028 | -0.1166 | No | ||
33 | NHLH2 | 6200021 | 5844 | 0.026 | -0.1219 | No | ||
34 | HOXC4 | 1940193 | 5909 | 0.025 | -0.1248 | No | ||
35 | HABP2 | 5360541 6350273 | 6203 | 0.021 | -0.1402 | No | ||
36 | VAMP3 | 7100050 | 6559 | 0.018 | -0.1590 | No | ||
37 | CREB5 | 2320368 | 6567 | 0.018 | -0.1590 | No | ||
38 | PCSK2 | 360017 430528 5900619 | 6790 | 0.016 | -0.1707 | No | ||
39 | ZFPM2 | 460072 | 6800 | 0.016 | -0.1708 | No | ||
40 | SLC6A15 | 5290176 6040017 | 6847 | 0.016 | -0.1729 | No | ||
41 | MID1 | 4070114 4760458 | 6849 | 0.016 | -0.1726 | No | ||
42 | PHOX2B | 5270075 | 6935 | 0.015 | -0.1769 | No | ||
43 | RAB3C | 5420072 | 7024 | 0.014 | -0.1813 | No | ||
44 | SOX5 | 2370576 2900167 3190128 5050528 | 7032 | 0.014 | -0.1814 | No | ||
45 | EN1 | 5360168 7050025 | 7312 | 0.013 | -0.1962 | No | ||
46 | EYA1 | 1450278 5220390 | 7412 | 0.012 | -0.2013 | No | ||
47 | OTP | 2630070 | 7497 | 0.012 | -0.2056 | No | ||
48 | ERG | 50154 1770739 | 7552 | 0.011 | -0.2083 | No | ||
49 | TBX5 | 2900132 6370484 | 7553 | 0.011 | -0.2080 | No | ||
50 | P518 | 3610435 | 7556 | 0.011 | -0.2079 | No | ||
51 | SOX18 | 2320086 | 7648 | 0.011 | -0.2126 | No | ||
52 | C1QTNF7 | 2970619 | 7750 | 0.010 | -0.2178 | No | ||
53 | ESRRG | 4010181 | 7822 | 0.010 | -0.2215 | No | ||
54 | LRRTM1 | 1690324 | 7909 | 0.010 | -0.2259 | No | ||
55 | GAD2 | 1400088 | 8134 | 0.009 | -0.2378 | No | ||
56 | SLC6A4 | 2230372 | 8248 | 0.008 | -0.2438 | No | ||
57 | NEUROD2 | 5290097 | 8306 | 0.008 | -0.2467 | No | ||
58 | ACMSD | 1450538 | 8429 | 0.008 | -0.2531 | No | ||
59 | PTPN22 | 1690647 7100239 | 8493 | 0.007 | -0.2564 | No | ||
60 | BAI3 | 940692 | 8567 | 0.007 | -0.2602 | No | ||
61 | ELP4 | 1230576 | 8737 | 0.006 | -0.2692 | No | ||
62 | ERMAP | 780156 | 8774 | 0.006 | -0.2710 | No | ||
63 | LHX6 | 2360731 3360397 | 8832 | 0.006 | -0.2739 | No | ||
64 | USF2 | 3870368 5570348 6940039 | 8882 | 0.006 | -0.2765 | No | ||
65 | RIMS2 | 670725 | 8922 | 0.006 | -0.2785 | No | ||
66 | ANGPT2 | 1230458 5720706 6040605 | 8928 | 0.006 | -0.2786 | No | ||
67 | MYF6 | 2690576 | 8948 | 0.006 | -0.2795 | No | ||
68 | PRDM13 | 1430022 | 8963 | 0.006 | -0.2801 | No | ||
69 | TCL1A | 3420367 | 9202 | 0.005 | -0.2929 | No | ||
70 | LGI1 | 1850020 | 9477 | 0.004 | -0.3077 | No | ||
71 | GABRB2 | 870059 | 9843 | 0.003 | -0.3274 | No | ||
72 | PURA | 3870156 | 9895 | 0.003 | -0.3301 | No | ||
73 | PLCB1 | 2570050 7100102 | 10158 | 0.002 | -0.3442 | No | ||
74 | ARX | 6900504 | 10218 | 0.002 | -0.3474 | No | ||
75 | LMO1 | 3170528 | 10605 | 0.001 | -0.3683 | No | ||
76 | PPARGC1A | 4670040 | 10674 | 0.001 | -0.3719 | No | ||
77 | HOXA11 | 6980133 | 10713 | 0.001 | -0.3740 | No | ||
78 | NPR3 | 1580239 | 10768 | 0.000 | -0.3769 | No | ||
79 | MYT1 | 6770524 | 10771 | 0.000 | -0.3770 | No | ||
80 | NEUROD6 | 4670731 | 10794 | 0.000 | -0.3782 | No | ||
81 | SATB2 | 2470181 | 10987 | -0.000 | -0.3886 | No | ||
82 | BOC | 5270348 | 11135 | -0.001 | -0.3965 | No | ||
83 | KLF15 | 4230164 | 11199 | -0.001 | -0.3999 | No | ||
84 | IRX4 | 1980102 | 11344 | -0.001 | -0.4077 | No | ||
85 | FGFR2 | 4670601 5570402 6940377 | 11419 | -0.001 | -0.4117 | No | ||
86 | FGF7 | 5390484 | 11438 | -0.002 | -0.4126 | No | ||
87 | NEUROG1 | 380341 | 11713 | -0.002 | -0.4274 | No | ||
88 | HSD17B2 | 3800541 | 11971 | -0.003 | -0.4412 | No | ||
89 | CLOCK | 1410070 2940292 3390075 | 12130 | -0.004 | -0.4497 | No | ||
90 | FGF12 | 1740446 2360037 | 12167 | -0.004 | -0.4516 | No | ||
91 | MLSTD1 | 3710184 | 12299 | -0.005 | -0.4586 | No | ||
92 | WNT7A | 1170315 | 12347 | -0.005 | -0.4610 | No | ||
93 | SLC26A7 | 1850398 3830377 | 12426 | -0.005 | -0.4651 | No | ||
94 | KCNJ16 | 4780273 | 12725 | -0.007 | -0.4811 | No | ||
95 | SDPR | 3360292 | 12957 | -0.008 | -0.4935 | No | ||
96 | PTPRD | 520008 3120097 | 12980 | -0.008 | -0.4945 | No | ||
97 | SLITRK3 | 5910041 | 13015 | -0.008 | -0.4961 | No | ||
98 | CDKL5 | 2450070 | 13081 | -0.009 | -0.4995 | No | ||
99 | HOXD8 | 3710156 | 13095 | -0.009 | -0.5000 | No | ||
100 | KCNIP2 | 60088 1780324 | 13110 | -0.009 | -0.5005 | No | ||
101 | DMP1 | 4760398 | 13185 | -0.009 | -0.5043 | No | ||
102 | CGA | 630403 | 13324 | -0.011 | -0.5116 | No | ||
103 | ALDH1A2 | 2320301 | 13414 | -0.011 | -0.5161 | No | ||
104 | MDGA1 | 1170139 | 13439 | -0.012 | -0.5172 | No | ||
105 | ITGA7 | 1230739 | 13481 | -0.012 | -0.5191 | No | ||
106 | PRRX1 | 4120193 4480390 | 13546 | -0.013 | -0.5223 | No | ||
107 | RARB | 430139 1410138 | 13691 | -0.014 | -0.5298 | No | ||
108 | APOBEC2 | 1690520 | 13877 | -0.017 | -0.5394 | No | ||
109 | NSD1 | 4560519 4780672 | 14165 | -0.022 | -0.5545 | No | ||
110 | FUT11 | 6040692 | 14181 | -0.022 | -0.5548 | No | ||
111 | NR4A3 | 2900021 5860095 5910039 | 14428 | -0.029 | -0.5675 | No | ||
112 | RHOBTB3 | 4010687 | 14611 | -0.036 | -0.5766 | No | ||
113 | SV2A | 1450039 5570685 | 14632 | -0.037 | -0.5768 | No | ||
114 | FHL1 | 60278 | 14840 | -0.049 | -0.5869 | No | ||
115 | AOC2 | 520348 3120008 | 14843 | -0.049 | -0.5860 | No | ||
116 | SLC12A6 | 610278 1980035 5340671 | 14900 | -0.052 | -0.5878 | No | ||
117 | ELF4 | 4850193 | 14976 | -0.056 | -0.5907 | No | ||
118 | RNF4 | 580286 1400152 | 15327 | -0.083 | -0.6078 | No | ||
119 | TCF4 | 520021 | 15471 | -0.097 | -0.6134 | No | ||
120 | MBNL2 | 3450707 | 15577 | -0.109 | -0.6166 | No | ||
121 | MYO10 | 3830576 5570092 | 15591 | -0.111 | -0.6149 | No | ||
122 | ZADH2 | 520438 | 15678 | -0.120 | -0.6169 | No | ||
123 | RAB5B | 130397 1980273 6900731 | 15709 | -0.123 | -0.6157 | No | ||
124 | KLHL5 | 3060484 6400292 | 15750 | -0.129 | -0.6150 | No | ||
125 | CUL3 | 1850520 | 15767 | -0.131 | -0.6130 | No | ||
126 | ZIC4 | 1500082 | 15904 | -0.148 | -0.6170 | No | ||
127 | FOXP3 | 940707 1850692 | 16316 | -0.219 | -0.6344 | No | ||
128 | CHCHD7 | 6620692 | 16354 | -0.227 | -0.6314 | No | ||
129 | AMMECR1 | 3800435 | 16463 | -0.254 | -0.6315 | No | ||
130 | CDC2L2 | 1400671 5290168 | 16694 | -0.317 | -0.6369 | Yes | ||
131 | HNRPA0 | 2680048 | 16695 | -0.317 | -0.6298 | Yes | ||
132 | KCNN3 | 6520600 6420138 | 16710 | -0.325 | -0.6234 | Yes | ||
133 | NCOR1 | 3710132 | 16902 | -0.380 | -0.6252 | Yes | ||
134 | ARID5A | 2450133 | 16961 | -0.402 | -0.6194 | Yes | ||
135 | CHD2 | 4070039 | 17007 | -0.417 | -0.6126 | Yes | ||
136 | LARGE | 6940068 | 17034 | -0.427 | -0.6045 | Yes | ||
137 | PLRG1 | 4480735 | 17094 | -0.444 | -0.5978 | Yes | ||
138 | FLI1 | 3990142 | 17232 | -0.505 | -0.5939 | Yes | ||
139 | NDUFA4 | 6860364 | 17330 | -0.547 | -0.5870 | Yes | ||
140 | CLK2 | 510079 2630736 | 17390 | -0.575 | -0.5774 | Yes | ||
141 | SLC20A1 | 6420014 | 17461 | -0.615 | -0.5674 | Yes | ||
142 | ATP2A2 | 1090075 3990279 | 17491 | -0.626 | -0.5551 | Yes | ||
143 | HOXA7 | 5910152 | 17605 | -0.687 | -0.5459 | Yes | ||
144 | GATA3 | 6130068 | 17815 | -0.824 | -0.5388 | Yes | ||
145 | RPA3 | 5700136 | 17876 | -0.871 | -0.5226 | Yes | ||
146 | PPP3CB | 6020156 | 17890 | -0.883 | -0.5036 | Yes | ||
147 | TRIM8 | 6130441 | 18037 | -1.028 | -0.4886 | Yes | ||
148 | SH3BGRL3 | 1850750 | 18049 | -1.032 | -0.4662 | Yes | ||
149 | TOB1 | 4150138 | 18063 | -1.050 | -0.4435 | Yes | ||
150 | SOX4 | 2260091 | 18158 | -1.199 | -0.4218 | Yes | ||
151 | MARCKS | 7040450 | 18194 | -1.252 | -0.3958 | Yes | ||
152 | ZFP36L1 | 2510138 4120048 | 18473 | -2.052 | -0.3651 | Yes | ||
153 | HSD11B1 | 450066 5550408 | 18477 | -2.066 | -0.3192 | Yes | ||
154 | DUSP6 | 5910286 7100070 | 18498 | -2.236 | -0.2704 | Yes | ||
155 | CCND2 | 5340167 | 18568 | -2.711 | -0.2137 | Yes | ||
156 | TLE4 | 1450064 1500519 | 18569 | -2.751 | -0.1524 | Yes | ||
157 | ETS2 | 360451 | 18573 | -2.835 | -0.0893 | Yes | ||
158 | BCL6 | 940100 | 18610 | -4.108 | 0.0003 | Yes |