Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$LEF1_Q2 |
Enrichment Score (ES) | 0.5049533 |
Normalized Enrichment Score (NES) | 1.2125467 |
Nominal p-value | 0.09233177 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SDHC | 3140347 6100156 | 5 | 5.850 | 0.1172 | Yes | ||
2 | TIMM10 | 610070 1450019 | 45 | 3.538 | 0.1862 | Yes | ||
3 | MFN2 | 2260195 6100164 | 49 | 3.475 | 0.2558 | Yes | ||
4 | CD160 | 4210377 | 129 | 2.429 | 0.3003 | Yes | ||
5 | NCDN | 50040 1980739 3520603 | 287 | 1.726 | 0.3265 | Yes | ||
6 | SLC6A9 | 2470520 | 292 | 1.714 | 0.3607 | Yes | ||
7 | SMYD2 | 5050026 | 343 | 1.597 | 0.3901 | Yes | ||
8 | NDUFS3 | 1690136 5340528 | 379 | 1.530 | 0.4189 | Yes | ||
9 | SYTL1 | 510487 | 475 | 1.360 | 0.4411 | Yes | ||
10 | ELOVL1 | 2450019 4760138 5340685 | 684 | 1.077 | 0.4515 | Yes | ||
11 | CNR2 | 2760398 | 723 | 1.051 | 0.4705 | Yes | ||
12 | DHCR24 | 840600 1050672 6290097 | 756 | 1.026 | 0.4894 | Yes | ||
13 | DYRK3 | 1090014 | 1215 | 0.706 | 0.4788 | Yes | ||
14 | SYT13 | 5910110 | 1518 | 0.555 | 0.4736 | Yes | ||
15 | TMEM9 | 130039 | 1550 | 0.544 | 0.4828 | Yes | ||
16 | DUSP10 | 2850673 3360064 | 1768 | 0.464 | 0.4804 | Yes | ||
17 | WNT8B | 4560301 | 1835 | 0.444 | 0.4858 | Yes | ||
18 | RPA2 | 2760301 5420195 | 1837 | 0.443 | 0.4946 | Yes | ||
19 | EFNA4 | 4280309 6550576 | 1989 | 0.398 | 0.4944 | Yes | ||
20 | GFRA1 | 3610152 | 2036 | 0.385 | 0.4997 | Yes | ||
21 | BMI1 | 3830026 2630204 | 2123 | 0.361 | 0.5023 | Yes | ||
22 | FRAG1 | 1050504 1170152 2030092 | 2202 | 0.343 | 0.5050 | Yes | ||
23 | SEMA4G | 5890026 | 2407 | 0.290 | 0.4997 | No | ||
24 | YARS | 70739 | 2576 | 0.245 | 0.4956 | No | ||
25 | NDUFC2 | 580075 | 2652 | 0.227 | 0.4961 | No | ||
26 | RUNX3 | 3800546 | 3198 | 0.140 | 0.4694 | No | ||
27 | PRKRIR | 2370402 | 3205 | 0.139 | 0.4718 | No | ||
28 | PDC | 3140400 3780184 | 3242 | 0.134 | 0.4726 | No | ||
29 | RRM1 | 4150433 | 3289 | 0.129 | 0.4727 | No | ||
30 | MOV10 | 50673 430577 3870280 | 3302 | 0.127 | 0.4746 | No | ||
31 | MRVI1 | 4810338 4850601 5900441 | 3477 | 0.110 | 0.4674 | No | ||
32 | AMPD3 | 610369 3360528 | 3914 | 0.080 | 0.4454 | No | ||
33 | GRK5 | 1940348 4670053 | 4326 | 0.061 | 0.4243 | No | ||
34 | SCUBE2 | 2850315 5130040 | 4376 | 0.059 | 0.4229 | No | ||
35 | SLC26A9 | 3440722 5340088 7510093 | 4611 | 0.052 | 0.4112 | No | ||
36 | SPOCK2 | 6650369 | 4629 | 0.051 | 0.4114 | No | ||
37 | SOX6 | 2940458 4070601 6840717 | 4638 | 0.051 | 0.4120 | No | ||
38 | BAI2 | 380632 630113 6650170 | 4651 | 0.051 | 0.4123 | No | ||
39 | VAX1 | 6660750 | 4802 | 0.046 | 0.4051 | No | ||
40 | OVOL1 | 1690131 | 4812 | 0.046 | 0.4056 | No | ||
41 | NPPA | 6550328 | 4931 | 0.043 | 0.4000 | No | ||
42 | NAV1 | 4210519 6620129 | 5127 | 0.038 | 0.3902 | No | ||
43 | HNRPR | 2320440 2900601 4610008 | 5135 | 0.038 | 0.3906 | No | ||
44 | SLC25A28 | 6590600 | 5287 | 0.035 | 0.3832 | No | ||
45 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.3753 | No | ||
46 | NHLH2 | 6200021 | 5844 | 0.026 | 0.3543 | No | ||
47 | GNG3 | 6980397 | 5948 | 0.024 | 0.3492 | No | ||
48 | PROX1 | 4210193 | 6128 | 0.022 | 0.3400 | No | ||
49 | HABP2 | 5360541 6350273 | 6203 | 0.021 | 0.3364 | No | ||
50 | SH2D4B | 670204 | 6261 | 0.021 | 0.3337 | No | ||
51 | DDR2 | 7050273 | 6424 | 0.019 | 0.3253 | No | ||
52 | AP4B1 | 2900300 | 6540 | 0.018 | 0.3195 | No | ||
53 | SLC17A6 | 4210576 | 6622 | 0.018 | 0.3154 | No | ||
54 | SFXN2 | 2650563 3140095 3830762 3870398 | 6892 | 0.016 | 0.3012 | No | ||
55 | PTCH2 | 2900092 | 7017 | 0.015 | 0.2948 | No | ||
56 | CGN | 5890139 6370167 6400537 | 7066 | 0.014 | 0.2924 | No | ||
57 | TCERG1L | 3360707 | 7379 | 0.012 | 0.2758 | No | ||
58 | DKK1 | 1940215 | 7528 | 0.011 | 0.2680 | No | ||
59 | ESRRG | 4010181 | 7822 | 0.010 | 0.2524 | No | ||
60 | PTPRJ | 4010707 | 7882 | 0.010 | 0.2494 | No | ||
61 | EPHA2 | 5890056 | 7993 | 0.009 | 0.2436 | No | ||
62 | WNT9A | 3830711 | 8247 | 0.008 | 0.2301 | No | ||
63 | RERE | 3940279 | 9213 | 0.005 | 0.1779 | No | ||
64 | LPHN2 | 4480010 | 9376 | 0.004 | 0.1692 | No | ||
65 | IL20 | 4850647 | 9632 | 0.004 | 0.1555 | No | ||
66 | DPYD | 6110095 | 9687 | 0.004 | 0.1526 | No | ||
67 | ARID1A | 2630022 1690551 4810110 | 9720 | 0.003 | 0.1510 | No | ||
68 | TLL2 | 6220040 | 9826 | 0.003 | 0.1454 | No | ||
69 | NEXN | 1240017 5290047 | 9849 | 0.003 | 0.1442 | No | ||
70 | PAX6 | 1190025 | 9898 | 0.003 | 0.1417 | No | ||
71 | CYP2E1 | 4480209 | 10098 | 0.002 | 0.1310 | No | ||
72 | SERPINC1 | 1780717 | 10103 | 0.002 | 0.1308 | No | ||
73 | RCN1 | 2480041 | 10117 | 0.002 | 0.1301 | No | ||
74 | GAB2 | 1410280 2340520 4280040 | 10137 | 0.002 | 0.1292 | No | ||
75 | CUBN | 630338 | 10165 | 0.002 | 0.1277 | No | ||
76 | LRRTM3 | 4210021 | 10217 | 0.002 | 0.1250 | No | ||
77 | COL13A1 | 4120079 | 10544 | 0.001 | 0.1074 | No | ||
78 | LMO1 | 3170528 | 10605 | 0.001 | 0.1042 | No | ||
79 | COL11A1 | 2100300 2810136 4200706 4810524 | 10629 | 0.001 | 0.1029 | No | ||
80 | KBTBD4 | 70465 3840093 | 10845 | 0.000 | 0.0913 | No | ||
81 | LIN28 | 6590672 | 10871 | 0.000 | 0.0899 | No | ||
82 | HIAT1 | 1580176 | 11052 | -0.000 | 0.0802 | No | ||
83 | SLC22A8 | 3520204 | 11226 | -0.001 | 0.0709 | No | ||
84 | MMP21 | 4480673 | 11925 | -0.003 | 0.0331 | No | ||
85 | CLCNKA | 1740050 | 12128 | -0.004 | 0.0223 | No | ||
86 | UBE2D1 | 1850400 | 12156 | -0.004 | 0.0209 | No | ||
87 | MPZ | 1990333 | 12251 | -0.004 | 0.0159 | No | ||
88 | PLA2G4A | 6380364 | 12253 | -0.004 | 0.0159 | No | ||
89 | RET | 3850746 | 12283 | -0.005 | 0.0145 | No | ||
90 | BSND | 1780041 | 12464 | -0.005 | 0.0048 | No | ||
91 | ELF5 | 3140156 5220020 | 12567 | -0.006 | -0.0006 | No | ||
92 | PVRL4 | 2340048 6220195 | 12641 | -0.006 | -0.0044 | No | ||
93 | IL19 | 6040142 | 12790 | -0.007 | -0.0123 | No | ||
94 | SORCS1 | 60411 5890373 | 12887 | -0.007 | -0.0173 | No | ||
95 | ZFYVE9 | 6980288 7100017 | 12909 | -0.008 | -0.0183 | No | ||
96 | ASB13 | 1090070 | 12995 | -0.008 | -0.0228 | No | ||
97 | NEUROG3 | 6980451 | 13090 | -0.009 | -0.0277 | No | ||
98 | PRRX1 | 4120193 4480390 | 13546 | -0.013 | -0.0521 | No | ||
99 | PHTF1 | 7050441 | 13568 | -0.013 | -0.0529 | No | ||
100 | RGL1 | 1500097 6900450 | 13709 | -0.015 | -0.0602 | No | ||
101 | LEMD1 | 3990132 5720187 | 13759 | -0.015 | -0.0626 | No | ||
102 | PAK1 | 4540315 | 13867 | -0.017 | -0.0680 | No | ||
103 | NEK7 | 4540026 | 13889 | -0.017 | -0.0688 | No | ||
104 | ARNT | 1170672 5670711 | 13985 | -0.019 | -0.0736 | No | ||
105 | LHX4 | 6940551 | 14005 | -0.019 | -0.0742 | No | ||
106 | BSCL2 | 2680671 | 14136 | -0.021 | -0.0809 | No | ||
107 | LRP8 | 3610746 5360035 | 14160 | -0.022 | -0.0817 | No | ||
108 | SLC16A9 | 6220497 | 14276 | -0.025 | -0.0874 | No | ||
109 | ANK3 | 1500161 2900435 4210154 6400100 | 14419 | -0.029 | -0.0945 | No | ||
110 | SV2A | 1450039 5570685 | 14632 | -0.037 | -0.1052 | No | ||
111 | ELAVL4 | 50735 3360086 5220167 | 15058 | -0.061 | -0.1270 | No | ||
112 | TRIM33 | 580619 2230280 3990433 6200747 | 15075 | -0.063 | -0.1266 | No | ||
113 | CACNB2 | 1500095 7330707 | 15206 | -0.072 | -0.1322 | No | ||
114 | ACTR1A | 5860070 | 15394 | -0.090 | -0.1405 | No | ||
115 | UAP1 | 3060093 | 15398 | -0.091 | -0.1389 | No | ||
116 | ADRBK1 | 1340333 | 15494 | -0.100 | -0.1420 | No | ||
117 | ADAM12 | 3390132 4070347 | 15538 | -0.104 | -0.1422 | No | ||
118 | SIPA1 | 5220687 | 15583 | -0.110 | -0.1424 | No | ||
119 | AHCYL1 | 540609 | 15619 | -0.114 | -0.1420 | No | ||
120 | S100A3 | 6400563 | 15636 | -0.115 | -0.1406 | No | ||
121 | ADD3 | 4150739 5390600 | 15732 | -0.127 | -0.1432 | No | ||
122 | DGAT2 | 5130685 | 15760 | -0.130 | -0.1420 | No | ||
123 | TACSTD2 | 6660341 | 15798 | -0.134 | -0.1413 | No | ||
124 | TCF7L2 | 2190348 5220113 | 15855 | -0.142 | -0.1415 | No | ||
125 | CNTF | 450128 870253 1780068 6520195 | 15873 | -0.145 | -0.1395 | No | ||
126 | ARL3 | 5690725 | 15936 | -0.154 | -0.1398 | No | ||
127 | ENTPD7 | 1980601 | 16058 | -0.172 | -0.1429 | No | ||
128 | PANK1 | 670091 6220605 | 16154 | -0.188 | -0.1443 | No | ||
129 | CREM | 840156 6380438 6660041 6660168 | 16266 | -0.211 | -0.1460 | No | ||
130 | SCAMP3 | 2360707 | 16337 | -0.223 | -0.1453 | No | ||
131 | GLUD1 | 4210372 | 16400 | -0.236 | -0.1439 | No | ||
132 | RNF11 | 3990068 5080458 | 16402 | -0.237 | -0.1392 | No | ||
133 | UBE4B | 780008 3610154 | 16501 | -0.264 | -0.1392 | No | ||
134 | EIF4EBP2 | 5670279 | 16953 | -0.398 | -0.1556 | No | ||
135 | PTPN7 | 3450110 | 17420 | -0.586 | -0.1691 | No | ||
136 | PRDM2 | 780278 1940692 | 17486 | -0.626 | -0.1600 | No | ||
137 | CEPT1 | 1940047 | 17490 | -0.626 | -0.1476 | No | ||
138 | TSG101 | 770148 | 17742 | -0.769 | -0.1458 | No | ||
139 | GADD45A | 2900717 | 17927 | -0.915 | -0.1373 | No | ||
140 | EIF4G2 | 3800575 6860184 | 17993 | -0.974 | -0.1213 | No | ||
141 | DCLRE1B | 540070 4730373 5550176 | 18050 | -1.033 | -0.1036 | No | ||
142 | SLC43A3 | 430168 5220400 | 18058 | -1.041 | -0.0831 | No | ||
143 | CAP1 | 2650278 | 18141 | -1.179 | -0.0638 | No | ||
144 | HSD11B1 | 450066 5550408 | 18477 | -2.066 | -0.0404 | No | ||
145 | UCP2 | 2190050 4070711 | 18524 | -2.386 | 0.0050 | No |