Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$CMYB_01 |
Enrichment Score (ES) | 0.50730664 |
Normalized Enrichment Score (NES) | 1.2317835 |
Nominal p-value | 0.07748538 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HES6 | 540411 6550504 | 13 | 4.961 | 0.0805 | Yes | ||
2 | PABPC1 | 2650180 2690253 6020632 1990270 | 22 | 4.554 | 0.1546 | Yes | ||
3 | PPP2R4 | 670280 2900097 | 33 | 3.879 | 0.2176 | Yes | ||
4 | DTX1 | 5900372 | 55 | 3.312 | 0.2706 | Yes | ||
5 | SH3KBP1 | 670102 2850458 7000309 | 167 | 2.200 | 0.3006 | Yes | ||
6 | RTN4 | 50725 630647 870097 870184 | 236 | 1.892 | 0.3279 | Yes | ||
7 | HIST1H1A | 1450131 | 255 | 1.822 | 0.3568 | Yes | ||
8 | UBE2H | 1980142 2970079 | 277 | 1.757 | 0.3844 | Yes | ||
9 | HIP2 | 2810095 3990369 4120301 | 401 | 1.487 | 0.4021 | Yes | ||
10 | ATF5 | 5670685 | 428 | 1.448 | 0.4244 | Yes | ||
11 | UBE2M | 2450215 | 442 | 1.416 | 0.4468 | Yes | ||
12 | RUVBL2 | 1190377 | 593 | 1.207 | 0.4585 | Yes | ||
13 | SCN5A | 4070017 | 595 | 1.202 | 0.4781 | Yes | ||
14 | FBXO34 | 4010671 5700647 6450026 | 697 | 1.066 | 0.4901 | Yes | ||
15 | PHF7 | 1510519 | 1335 | 0.636 | 0.4660 | Yes | ||
16 | NDST2 | 6290711 | 1483 | 0.568 | 0.4673 | Yes | ||
17 | LYAR | 7000402 | 1562 | 0.539 | 0.4719 | Yes | ||
18 | PER1 | 3290315 | 1692 | 0.490 | 0.4729 | Yes | ||
19 | NLGN2 | 5900592 | 1856 | 0.438 | 0.4713 | Yes | ||
20 | PRR3 | 3440112 | 1903 | 0.427 | 0.4758 | Yes | ||
21 | DAP3 | 1660528 2120039 5420593 | 1921 | 0.423 | 0.4818 | Yes | ||
22 | BAP1 | 3830131 | 1937 | 0.418 | 0.4878 | Yes | ||
23 | DLX1 | 360168 | 1962 | 0.410 | 0.4932 | Yes | ||
24 | SLC39A3 | 3990397 4670494 | 2031 | 0.386 | 0.4959 | Yes | ||
25 | TYRO3 | 3130193 | 2193 | 0.345 | 0.4928 | Yes | ||
26 | BHLHB2 | 7040603 | 2302 | 0.317 | 0.4921 | Yes | ||
27 | NUP62 | 1240128 | 2317 | 0.313 | 0.4965 | Yes | ||
28 | ABHD2 | 4850504 6840010 | 2343 | 0.306 | 0.5002 | Yes | ||
29 | ZNF148 | 6420403 | 2414 | 0.289 | 0.5011 | Yes | ||
30 | RBM14 | 5340731 5690315 | 2517 | 0.260 | 0.4998 | Yes | ||
31 | HOXB4 | 540131 | 2527 | 0.258 | 0.5036 | Yes | ||
32 | IGFBP4 | 2680309 5420441 | 2536 | 0.256 | 0.5073 | Yes | ||
33 | OAZ2 | 2810110 | 2682 | 0.221 | 0.5031 | No | ||
34 | BCL9L | 6940053 | 2850 | 0.189 | 0.4971 | No | ||
35 | EGR3 | 6940128 | 3087 | 0.153 | 0.4868 | No | ||
36 | NR2E1 | 4730288 | 3140 | 0.147 | 0.4864 | No | ||
37 | ARF6 | 3520026 | 3246 | 0.134 | 0.4829 | No | ||
38 | MXI1 | 5050064 5130484 | 3466 | 0.111 | 0.4729 | No | ||
39 | RBM6 | 840279 3840563 4780129 6020446 | 3542 | 0.105 | 0.4705 | No | ||
40 | SNRPD1 | 4480162 | 3628 | 0.098 | 0.4675 | No | ||
41 | PIK3R3 | 1770333 | 3672 | 0.095 | 0.4668 | No | ||
42 | ASH1L | 2510402 5360687 6650685 | 3827 | 0.086 | 0.4598 | No | ||
43 | BARHL1 | 4210113 | 4104 | 0.071 | 0.4460 | No | ||
44 | TPM3 | 670600 3170296 5670167 6650471 | 4171 | 0.068 | 0.4436 | No | ||
45 | ACCN2 | 6450465 | 4351 | 0.060 | 0.4349 | No | ||
46 | ETV4 | 2450605 | 4373 | 0.059 | 0.4347 | No | ||
47 | XPO5 | 2850286 | 4424 | 0.057 | 0.4329 | No | ||
48 | RPL4 | 2940014 5420324 | 4641 | 0.051 | 0.4221 | No | ||
49 | GMPR2 | 4920204 | 4762 | 0.047 | 0.4163 | No | ||
50 | CRAT | 540020 2060364 3520148 | 4851 | 0.045 | 0.4123 | No | ||
51 | GNB2 | 2350053 | 4878 | 0.044 | 0.4116 | No | ||
52 | PHF15 | 6550066 6860673 | 4908 | 0.043 | 0.4107 | No | ||
53 | IL4 | 6020537 | 5032 | 0.041 | 0.4047 | No | ||
54 | HOXB8 | 3710450 | 5077 | 0.040 | 0.4030 | No | ||
55 | CITED2 | 5670114 5130088 | 5161 | 0.038 | 0.3991 | No | ||
56 | YBX2 | 3520441 | 5189 | 0.037 | 0.3983 | No | ||
57 | MFN1 | 5080546 6200292 | 5237 | 0.036 | 0.3963 | No | ||
58 | HOXB3 | 520292 | 5339 | 0.034 | 0.3914 | No | ||
59 | WNT3 | 2360685 | 5451 | 0.032 | 0.3859 | No | ||
60 | HEBP1 | 6100279 | 5470 | 0.032 | 0.3855 | No | ||
61 | CANX | 4760402 | 5561 | 0.030 | 0.3811 | No | ||
62 | GPR21 | 6520152 | 5952 | 0.024 | 0.3604 | No | ||
63 | ANAPC2 | 6660438 | 5957 | 0.024 | 0.3605 | No | ||
64 | KCNJ15 | 70176 6900750 | 6059 | 0.023 | 0.3555 | No | ||
65 | MYOG | 3190672 | 6547 | 0.018 | 0.3294 | No | ||
66 | POGZ | 870348 7040286 | 6788 | 0.016 | 0.3166 | No | ||
67 | PHOX2B | 5270075 | 6935 | 0.015 | 0.3090 | No | ||
68 | APLN | 6620632 | 6982 | 0.015 | 0.3067 | No | ||
69 | MAZ | 3360121 6940750 | 7220 | 0.013 | 0.2941 | No | ||
70 | ODF2 | 1660487 4150484 5690706 6940121 | 7276 | 0.013 | 0.2913 | No | ||
71 | SSNA1 | 360593 | 7324 | 0.013 | 0.2890 | No | ||
72 | EYA1 | 1450278 5220390 | 7412 | 0.012 | 0.2845 | No | ||
73 | E2F3 | 50162 460180 | 7560 | 0.011 | 0.2767 | No | ||
74 | WNT4 | 4150619 | 7575 | 0.011 | 0.2761 | No | ||
75 | ARHGAP12 | 1050181 | 7751 | 0.010 | 0.2668 | No | ||
76 | STMN1 | 1990717 | 7825 | 0.010 | 0.2630 | No | ||
77 | PAFAH1B1 | 4230333 6420121 6450066 | 8128 | 0.009 | 0.2468 | No | ||
78 | NR3C2 | 2480324 6400093 | 8408 | 0.008 | 0.2318 | No | ||
79 | HR | 2690095 6200300 | 8757 | 0.006 | 0.2130 | No | ||
80 | DIO1 | 4570279 5290112 5420148 | 8878 | 0.006 | 0.2066 | No | ||
81 | CDC14B | 2320497 3360162 | 9168 | 0.005 | 0.1911 | No | ||
82 | WAC | 5340390 5910164 | 9182 | 0.005 | 0.1904 | No | ||
83 | PBX1 | 6660301 | 9232 | 0.005 | 0.1879 | No | ||
84 | GPC4 | 5910408 | 9341 | 0.004 | 0.1821 | No | ||
85 | SPAG9 | 580497 2510180 4210685 | 9380 | 0.004 | 0.1801 | No | ||
86 | BHLHB5 | 6510520 | 9463 | 0.004 | 0.1757 | No | ||
87 | YWHAZ | 1230717 | 9466 | 0.004 | 0.1757 | No | ||
88 | PURA | 3870156 | 9895 | 0.003 | 0.1525 | No | ||
89 | PITX2 | 870537 2690139 | 10667 | 0.001 | 0.1108 | No | ||
90 | FST | 1110600 | 10668 | 0.001 | 0.1108 | No | ||
91 | ARMET | 5130670 | 11044 | -0.000 | 0.0905 | No | ||
92 | SULF1 | 430575 | 11205 | -0.001 | 0.0818 | No | ||
93 | AP2B1 | 1450184 2370148 3520139 4850593 | 11213 | -0.001 | 0.0815 | No | ||
94 | PIK3AP1 | 6760008 | 11359 | -0.001 | 0.0736 | No | ||
95 | SPATS2 | 2360066 | 11409 | -0.001 | 0.0710 | No | ||
96 | FGF16 | 4210440 | 11639 | -0.002 | 0.0586 | No | ||
97 | LHX1 | 1690100 | 11699 | -0.002 | 0.0555 | No | ||
98 | STAG2 | 4540132 | 11810 | -0.003 | 0.0495 | No | ||
99 | AVPR1B | 1190707 | 11982 | -0.003 | 0.0403 | No | ||
100 | IER5 | 2350575 | 12012 | -0.003 | 0.0388 | No | ||
101 | TRIM37 | 5270091 | 12056 | -0.004 | 0.0366 | No | ||
102 | FGF12 | 1740446 2360037 | 12167 | -0.004 | 0.0307 | No | ||
103 | ATP2B2 | 3780397 | 12439 | -0.005 | 0.0161 | No | ||
104 | ERBB4 | 4610400 4810017 | 12582 | -0.006 | 0.0085 | No | ||
105 | TCF1 | 5390022 | 12587 | -0.006 | 0.0083 | No | ||
106 | ZNF462 | 6900100 | 12688 | -0.006 | 0.0030 | No | ||
107 | WNT9B | 50095 | 13072 | -0.009 | -0.0176 | No | ||
108 | TIMP4 | 6110433 | 13078 | -0.009 | -0.0177 | No | ||
109 | NEUROG3 | 6980451 | 13090 | -0.009 | -0.0182 | No | ||
110 | SCML2 | 3290603 | 13190 | -0.009 | -0.0234 | No | ||
111 | HOXA2 | 2120121 | 13667 | -0.014 | -0.0489 | No | ||
112 | RBBP6 | 2320129 | 13716 | -0.015 | -0.0513 | No | ||
113 | SPINT2 | 2630039 6110519 | 14335 | -0.026 | -0.0843 | No | ||
114 | ASXL2 | 130670 | 14336 | -0.026 | -0.0839 | No | ||
115 | NRGN | 4280433 | 14541 | -0.033 | -0.0944 | No | ||
116 | ARL1 | 450619 | 14865 | -0.050 | -0.1111 | No | ||
117 | PAPOLG | 2470400 | 14923 | -0.053 | -0.1133 | No | ||
118 | MORF4L1 | 3190100 | 15036 | -0.060 | -0.1184 | No | ||
119 | PNRC2 | 3360309 | 15073 | -0.063 | -0.1193 | No | ||
120 | DVL2 | 6110162 | 15099 | -0.065 | -0.1196 | No | ||
121 | RNF38 | 1940746 3140133 3840601 | 15210 | -0.072 | -0.1244 | No | ||
122 | ITGA5 | 5550520 | 15278 | -0.078 | -0.1268 | No | ||
123 | PDGFB | 3060440 6370008 | 15328 | -0.083 | -0.1281 | No | ||
124 | NLK | 2030010 2450041 | 15553 | -0.106 | -0.1385 | No | ||
125 | TOM1 | 940398 2190053 | 15617 | -0.114 | -0.1400 | No | ||
126 | NEDD8 | 2350722 | 15723 | -0.126 | -0.1436 | No | ||
127 | ADD3 | 4150739 5390600 | 15732 | -0.127 | -0.1420 | No | ||
128 | MGLL | 2030446 4210520 | 15738 | -0.128 | -0.1402 | No | ||
129 | CRSP7 | 4230408 | 15778 | -0.132 | -0.1401 | No | ||
130 | ZIC4 | 1500082 | 15904 | -0.148 | -0.1445 | No | ||
131 | KLF5 | 3840348 | 15921 | -0.152 | -0.1429 | No | ||
132 | VAPA | 2480594 | 15987 | -0.162 | -0.1437 | No | ||
133 | MLLT10 | 1410288 3290142 | 15992 | -0.163 | -0.1413 | No | ||
134 | USP2 | 1190292 1240253 4850035 | 16094 | -0.176 | -0.1439 | No | ||
135 | RANBP1 | 430215 1090180 | 16346 | -0.225 | -0.1538 | No | ||
136 | POMT1 | 2680047 3440040 6660114 | 16367 | -0.230 | -0.1511 | No | ||
137 | AEBP2 | 2970603 | 16594 | -0.292 | -0.1585 | No | ||
138 | RALY | 940427 1740066 | 16737 | -0.332 | -0.1608 | No | ||
139 | SP1 | 6590017 | 16789 | -0.347 | -0.1579 | No | ||
140 | ROCK1 | 130044 | 16849 | -0.365 | -0.1551 | No | ||
141 | NCOA5 | 2060647 | 16872 | -0.371 | -0.1502 | No | ||
142 | MTCH2 | 3780603 6620215 | 16879 | -0.372 | -0.1445 | No | ||
143 | MORF4L2 | 6450133 | 17074 | -0.438 | -0.1478 | No | ||
144 | KPNB1 | 1690138 | 17159 | -0.476 | -0.1446 | No | ||
145 | ALDH6A1 | 1770746 | 17241 | -0.508 | -0.1406 | No | ||
146 | DHX30 | 2480494 | 17256 | -0.514 | -0.1330 | No | ||
147 | CALM3 | 3390288 | 17358 | -0.561 | -0.1293 | No | ||
148 | MNAT1 | 730292 2350364 | 17391 | -0.575 | -0.1216 | No | ||
149 | BRPF1 | 3170139 | 17437 | -0.598 | -0.1142 | No | ||
150 | HTF9C | 3190048 4120132 | 17522 | -0.642 | -0.1083 | No | ||
151 | NFYA | 5860368 | 17576 | -0.672 | -0.1001 | No | ||
152 | IL4I1 | 3190161 | 17638 | -0.703 | -0.0919 | No | ||
153 | ITPKB | 2900195 7100039 | 17735 | -0.764 | -0.0846 | No | ||
154 | GSK3B | 5360348 | 17827 | -0.830 | -0.0760 | No | ||
155 | POLH | 2690528 | 17872 | -0.868 | -0.0641 | No | ||
156 | CSDA | 2470092 3060053 4780056 | 17909 | -0.906 | -0.0513 | No | ||
157 | NFE2 | 3710373 | 17947 | -0.938 | -0.0379 | No | ||
158 | DNAJB1 | 1090041 | 18244 | -1.357 | -0.0317 | No | ||
159 | EPC1 | 1570050 5290095 6900193 | 18284 | -1.437 | -0.0103 | No | ||
160 | ARNTL | 3170463 | 18381 | -1.727 | 0.0127 | No |