Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$CACCCBINDINGFACTOR_Q6 |
Enrichment Score (ES) | 0.4890332 |
Normalized Enrichment Score (NES) | 1.2077787 |
Nominal p-value | 0.102453105 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EEF1A1 | 1980193 1990195 4670735 | 2 | 8.490 | 0.1407 | Yes | ||
2 | RGMA | 2450711 | 74 | 2.932 | 0.1854 | Yes | ||
3 | PCBP4 | 6350722 | 78 | 2.872 | 0.2329 | Yes | ||
4 | ETV5 | 110017 | 222 | 1.935 | 0.2572 | Yes | ||
5 | CDKN1A | 4050088 6400706 | 246 | 1.863 | 0.2868 | Yes | ||
6 | SLC6A9 | 2470520 | 292 | 1.714 | 0.3128 | Yes | ||
7 | SDC1 | 3440471 6350408 | 321 | 1.645 | 0.3386 | Yes | ||
8 | EFEMP2 | 5550086 | 415 | 1.467 | 0.3579 | Yes | ||
9 | HES1 | 4810280 | 514 | 1.306 | 0.3742 | Yes | ||
10 | EPHB2 | 1090288 1410377 2100541 | 602 | 1.194 | 0.3893 | Yes | ||
11 | OTUB1 | 610551 | 648 | 1.126 | 0.4055 | Yes | ||
12 | CDK4 | 540075 4540600 | 755 | 1.026 | 0.4168 | Yes | ||
13 | ATP5G1 | 5290019 | 777 | 1.007 | 0.4323 | Yes | ||
14 | SMYD5 | 6220025 | 877 | 0.931 | 0.4424 | Yes | ||
15 | PPP1R1B | 5290403 5550324 | 1192 | 0.729 | 0.4375 | Yes | ||
16 | PLTP | 630110 130497 4050139 | 1208 | 0.713 | 0.4485 | Yes | ||
17 | PMP22 | 4010239 6550072 | 1383 | 0.615 | 0.4492 | Yes | ||
18 | GEMIN7 | 2320433 | 1543 | 0.546 | 0.4497 | Yes | ||
19 | BMF | 610102 | 1614 | 0.522 | 0.4545 | Yes | ||
20 | MRPL14 | 2370168 | 1638 | 0.512 | 0.4618 | Yes | ||
21 | PRKAG1 | 6450091 | 1656 | 0.503 | 0.4692 | Yes | ||
22 | BLMH | 1410438 | 1742 | 0.474 | 0.4724 | Yes | ||
23 | SH3GLB2 | 2030086 | 1873 | 0.435 | 0.4726 | Yes | ||
24 | FKBP2 | 2320025 | 1944 | 0.417 | 0.4757 | Yes | ||
25 | DLX1 | 360168 | 1962 | 0.410 | 0.4816 | Yes | ||
26 | HMGN2 | 3140091 | 2032 | 0.386 | 0.4842 | Yes | ||
27 | LRP1 | 6270386 | 2060 | 0.378 | 0.4890 | Yes | ||
28 | CASKIN2 | 2030113 | 2376 | 0.297 | 0.4769 | No | ||
29 | LAD1 | 4850408 | 2495 | 0.265 | 0.4749 | No | ||
30 | YTHDF2 | 4060332 4610279 | 2569 | 0.248 | 0.4750 | No | ||
31 | YARS | 70739 | 2576 | 0.245 | 0.4788 | No | ||
32 | MYO1C | 3190398 | 2671 | 0.225 | 0.4774 | No | ||
33 | FARP1 | 5290102 7100341 | 2750 | 0.205 | 0.4766 | No | ||
34 | EFNA3 | 6370390 | 2848 | 0.189 | 0.4744 | No | ||
35 | LGI4 | 1570577 | 3073 | 0.156 | 0.4649 | No | ||
36 | DUSP14 | 1230358 | 3232 | 0.135 | 0.4586 | No | ||
37 | KCNH7 | 7510068 | 3429 | 0.115 | 0.4498 | No | ||
38 | PLA2G6 | 6040161 | 3461 | 0.112 | 0.4500 | No | ||
39 | LTB4R | 1770056 | 3581 | 0.102 | 0.4452 | No | ||
40 | LTBR | 2450341 | 3666 | 0.095 | 0.4423 | No | ||
41 | MIP | 6520333 | 3704 | 0.092 | 0.4418 | No | ||
42 | HOXC6 | 3850133 4920736 | 3792 | 0.088 | 0.4385 | No | ||
43 | IGFBP5 | 2360592 | 3826 | 0.086 | 0.4382 | No | ||
44 | LBX1 | 1300164 4060204 | 3958 | 0.078 | 0.4324 | No | ||
45 | OTX2 | 1190471 | 4293 | 0.063 | 0.4153 | No | ||
46 | ENTPD2 | 4590739 | 4299 | 0.062 | 0.4160 | No | ||
47 | GRK5 | 1940348 4670053 | 4326 | 0.061 | 0.4156 | No | ||
48 | ABCG4 | 3440458 | 4371 | 0.059 | 0.4142 | No | ||
49 | SERPINE1 | 4210403 | 4584 | 0.053 | 0.4036 | No | ||
50 | PTGDS | 3610519 | 4603 | 0.052 | 0.4035 | No | ||
51 | MNT | 4920575 | 4693 | 0.049 | 0.3995 | No | ||
52 | FLNC | 2360048 5050270 | 4791 | 0.046 | 0.3950 | No | ||
53 | GNB2 | 2350053 | 4878 | 0.044 | 0.3911 | No | ||
54 | INHA | 6100102 | 4882 | 0.044 | 0.3916 | No | ||
55 | SEMA4C | 1980315 | 4942 | 0.042 | 0.3891 | No | ||
56 | KREMEN2 | 110025 | 4970 | 0.042 | 0.3884 | No | ||
57 | NINJ2 | 3120131 | 4994 | 0.041 | 0.3878 | No | ||
58 | HOXB8 | 3710450 | 5077 | 0.040 | 0.3840 | No | ||
59 | CITED2 | 5670114 5130088 | 5161 | 0.038 | 0.3802 | No | ||
60 | NRG1 | 1050332 | 5184 | 0.037 | 0.3796 | No | ||
61 | KCNN4 | 2680129 | 5218 | 0.037 | 0.3784 | No | ||
62 | RGS6 | 6040601 | 5425 | 0.033 | 0.3678 | No | ||
63 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.3672 | No | ||
64 | WNT3 | 2360685 | 5451 | 0.032 | 0.3675 | No | ||
65 | C1S | 840184 6840114 | 5908 | 0.025 | 0.3432 | No | ||
66 | HOXC4 | 1940193 | 5909 | 0.025 | 0.3436 | No | ||
67 | CALM1 | 380128 | 6258 | 0.021 | 0.3251 | No | ||
68 | PI15 | 3840133 | 6272 | 0.020 | 0.3247 | No | ||
69 | JPH4 | 780020 | 6303 | 0.020 | 0.3235 | No | ||
70 | DLD | 4150403 6590341 | 6307 | 0.020 | 0.3236 | No | ||
71 | RTKN | 5910253 6380082 | 6400 | 0.019 | 0.3190 | No | ||
72 | CHD4 | 5420059 6130338 6380717 | 6413 | 0.019 | 0.3186 | No | ||
73 | TUSC3 | 1690411 | 6574 | 0.018 | 0.3102 | No | ||
74 | MAGEL2 | 7050619 | 6602 | 0.018 | 0.3091 | No | ||
75 | KCND1 | 6860278 | 6653 | 0.017 | 0.3066 | No | ||
76 | NLN | 1450576 5870575 | 7082 | 0.014 | 0.2837 | No | ||
77 | GFAP | 2060092 | 7266 | 0.013 | 0.2740 | No | ||
78 | BMP2 | 6620687 | 7299 | 0.013 | 0.2724 | No | ||
79 | MID2 | 4120309 | 7496 | 0.012 | 0.2620 | No | ||
80 | PLS3 | 3290082 | 7841 | 0.010 | 0.2435 | No | ||
81 | PTPRJ | 4010707 | 7882 | 0.010 | 0.2415 | No | ||
82 | OTX1 | 2510215 | 8107 | 0.009 | 0.2295 | No | ||
83 | SPRY2 | 5860184 | 8464 | 0.007 | 0.2103 | No | ||
84 | HOXB5 | 2900538 | 8568 | 0.007 | 0.2048 | No | ||
85 | CNTFR | 4480092 6200064 | 8722 | 0.007 | 0.1967 | No | ||
86 | HR | 2690095 6200300 | 8757 | 0.006 | 0.1949 | No | ||
87 | SEMA3B | 5570563 | 8794 | 0.006 | 0.1931 | No | ||
88 | ADRA2C | 5130154 | 8884 | 0.006 | 0.1883 | No | ||
89 | SOX15 | 2470603 | 9140 | 0.005 | 0.1746 | No | ||
90 | CRLF1 | 3520092 | 9198 | 0.005 | 0.1716 | No | ||
91 | SPAG9 | 580497 2510180 4210685 | 9380 | 0.004 | 0.1618 | No | ||
92 | GSH1 | 2760242 | 9384 | 0.004 | 0.1617 | No | ||
93 | XPO1 | 540707 | 9449 | 0.004 | 0.1583 | No | ||
94 | LGI1 | 1850020 | 9477 | 0.004 | 0.1569 | No | ||
95 | SLC12A5 | 1980692 | 9505 | 0.004 | 0.1555 | No | ||
96 | SIX4 | 6760022 | 9583 | 0.004 | 0.1514 | No | ||
97 | RTN2 | 4480538 | 9656 | 0.004 | 0.1476 | No | ||
98 | HIF1A | 5670605 | 9787 | 0.003 | 0.1406 | No | ||
99 | F11R | 1740128 | 10053 | 0.002 | 0.1263 | No | ||
100 | TAGLN | 6660280 | 10269 | 0.002 | 0.1146 | No | ||
101 | CHRM1 | 4280619 | 10311 | 0.002 | 0.1124 | No | ||
102 | AMBN | 4150170 | 10442 | 0.001 | 0.1054 | No | ||
103 | ITGB4 | 1740021 3840482 | 10509 | 0.001 | 0.1019 | No | ||
104 | EPHA7 | 1190288 4010278 | 10549 | 0.001 | 0.0998 | No | ||
105 | FGF11 | 840292 | 10594 | 0.001 | 0.0974 | No | ||
106 | PORCN | 5050519 | 10773 | 0.000 | 0.0877 | No | ||
107 | CALCR | 1690494 | 10921 | -0.000 | 0.0798 | No | ||
108 | BOC | 5270348 | 11135 | -0.001 | 0.0682 | No | ||
109 | MLLT7 | 4480707 | 11196 | -0.001 | 0.0650 | No | ||
110 | SULF1 | 430575 | 11205 | -0.001 | 0.0646 | No | ||
111 | KCNH8 | 3940129 | 11298 | -0.001 | 0.0596 | No | ||
112 | SGTB | 460170 | 11307 | -0.001 | 0.0592 | No | ||
113 | GRM3 | 4540242 | 11573 | -0.002 | 0.0448 | No | ||
114 | RBMS3 | 6110722 | 11650 | -0.002 | 0.0408 | No | ||
115 | STAG2 | 4540132 | 11810 | -0.003 | 0.0322 | No | ||
116 | FOXF2 | 1240091 | 11898 | -0.003 | 0.0275 | No | ||
117 | LIN7B | 1850546 3850288 6760110 | 11934 | -0.003 | 0.0257 | No | ||
118 | LHX9 | 2350112 | 12243 | -0.004 | 0.0090 | No | ||
119 | PRDM16 | 4120541 | 12422 | -0.005 | -0.0005 | No | ||
120 | PVRL4 | 2340048 6220195 | 12641 | -0.006 | -0.0123 | No | ||
121 | CPLX1 | 2510735 | 12680 | -0.006 | -0.0142 | No | ||
122 | MTSS1 | 780435 2370114 | 12710 | -0.006 | -0.0157 | No | ||
123 | STMN4 | 2900091 | 12782 | -0.007 | -0.0194 | No | ||
124 | UBE2R2 | 1230504 | 12798 | -0.007 | -0.0201 | No | ||
125 | HPN | 2470167 5220181 | 12821 | -0.007 | -0.0212 | No | ||
126 | SLC25A13 | 4920072 5690722 | 12878 | -0.007 | -0.0241 | No | ||
127 | RARG | 6760136 | 13031 | -0.008 | -0.0322 | No | ||
128 | TRPV3 | 540341 | 13046 | -0.008 | -0.0328 | No | ||
129 | MAPT | 360706 1230706 | 13208 | -0.010 | -0.0414 | No | ||
130 | RAD23B | 2190671 | 13348 | -0.011 | -0.0488 | No | ||
131 | JARID2 | 6290538 | 13395 | -0.011 | -0.0511 | No | ||
132 | MEIS1 | 1400575 | 13430 | -0.012 | -0.0527 | No | ||
133 | HOXB9 | 2640687 | 13575 | -0.013 | -0.0603 | No | ||
134 | RARB | 430139 1410138 | 13691 | -0.014 | -0.0663 | No | ||
135 | GNAO1 | 2510292 6590487 | 13937 | -0.018 | -0.0793 | No | ||
136 | LHX4 | 6940551 | 14005 | -0.019 | -0.0826 | No | ||
137 | SHH | 5570400 | 14094 | -0.020 | -0.0871 | No | ||
138 | CNKSR2 | 110348 1770372 | 14302 | -0.025 | -0.0979 | No | ||
139 | USP25 | 3520035 | 14394 | -0.028 | -0.1023 | No | ||
140 | PCF11 | 1240180 | 14480 | -0.031 | -0.1064 | No | ||
141 | YWHAE | 5310435 | 14503 | -0.032 | -0.1071 | No | ||
142 | KCNAB3 | 2470725 | 14696 | -0.040 | -0.1168 | No | ||
143 | ADCY5 | 1410402 | 14825 | -0.048 | -0.1230 | No | ||
144 | TRIM33 | 580619 2230280 3990433 6200747 | 15075 | -0.063 | -0.1355 | No | ||
145 | ITGA5 | 5550520 | 15278 | -0.078 | -0.1451 | No | ||
146 | SPRY4 | 1570594 | 15480 | -0.099 | -0.1544 | No | ||
147 | EIF4E | 1580403 70133 6380215 | 15566 | -0.108 | -0.1572 | No | ||
148 | SP4 | 3850176 | 15664 | -0.118 | -0.1605 | No | ||
149 | ZADH2 | 520438 | 15678 | -0.120 | -0.1592 | No | ||
150 | ASB7 | 520242 2450088 3990563 4280538 | 15730 | -0.127 | -0.1599 | No | ||
151 | BRUNOL4 | 4490452 5080451 | 15850 | -0.141 | -0.1640 | No | ||
152 | EIF5A | 1500059 5290022 6370026 | 15867 | -0.144 | -0.1625 | No | ||
153 | ZHX2 | 2900452 | 16244 | -0.206 | -0.1795 | No | ||
154 | CRK | 1230162 4780128 | 16249 | -0.206 | -0.1763 | No | ||
155 | CREM | 840156 6380438 6660041 6660168 | 16266 | -0.211 | -0.1737 | No | ||
156 | STK16 | 1740154 | 16303 | -0.217 | -0.1720 | No | ||
157 | BCL11A | 6860369 | 16672 | -0.312 | -0.1868 | No | ||
158 | LIMK2 | 2650446 4050164 | 16802 | -0.350 | -0.1880 | No | ||
159 | ZFX | 5900400 | 16812 | -0.352 | -0.1827 | No | ||
160 | TBL1X | 6400524 | 16897 | -0.379 | -0.1809 | No | ||
161 | SFRS5 | 3450176 6350008 | 16938 | -0.392 | -0.1766 | No | ||
162 | SLC9A3R1 | 6020373 | 17061 | -0.435 | -0.1760 | No | ||
163 | DCTN1 | 1450056 6590022 | 17070 | -0.437 | -0.1692 | No | ||
164 | MORF4L2 | 6450133 | 17074 | -0.438 | -0.1621 | No | ||
165 | PIP5K2B | 6520156 6620541 | 17291 | -0.525 | -0.1651 | No | ||
166 | LDB1 | 5270601 | 17329 | -0.545 | -0.1581 | No | ||
167 | CAMTA2 | 3990075 | 17554 | -0.659 | -0.1593 | No | ||
168 | DIABLO | 2360170 | 17610 | -0.690 | -0.1508 | No | ||
169 | PHF12 | 870400 3130687 | 17693 | -0.738 | -0.1430 | No | ||
170 | PABPN1 | 460519 | 17784 | -0.793 | -0.1348 | No | ||
171 | JUP | 2510671 | 17794 | -0.799 | -0.1220 | No | ||
172 | IL2RG | 4120273 | 17992 | -0.973 | -0.1166 | No | ||
173 | DYRK1A | 3190181 | 18053 | -1.036 | -0.1026 | No | ||
174 | FBS1 | 2570520 | 18070 | -1.061 | -0.0859 | No | ||
175 | RGS14 | 380086 | 18296 | -1.464 | -0.0738 | No | ||
176 | KLF13 | 4670563 | 18402 | -1.779 | -0.0500 | No | ||
177 | ARL6IP2 | 770494 4590176 6620427 | 18418 | -1.824 | -0.0206 | No | ||
178 | BRD2 | 1450300 5340484 6100605 | 18440 | -1.886 | 0.0095 | No |