Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q6 |
Enrichment Score (ES) | 0.49347645 |
Normalized Enrichment Score (NES) | 1.2121922 |
Nominal p-value | 0.08802309 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ECM1 | 940068 5390309 | 36 | 3.763 | 0.0569 | Yes | ||
2 | LMNA | 520471 1500075 3190167 4210020 | 152 | 2.286 | 0.0864 | Yes | ||
3 | ENO1 | 5340128 | 161 | 2.215 | 0.1206 | Yes | ||
4 | ELA1 | 3390167 | 189 | 2.067 | 0.1515 | Yes | ||
5 | NDRG2 | 450403 | 220 | 1.946 | 0.1803 | Yes | ||
6 | TAGLN2 | 4560121 | 221 | 1.943 | 0.2106 | Yes | ||
7 | ETV5 | 110017 | 222 | 1.935 | 0.2409 | Yes | ||
8 | RTN4 | 50725 630647 870097 870184 | 236 | 1.892 | 0.2698 | Yes | ||
9 | ALDOA | 6290672 | 242 | 1.875 | 0.2988 | Yes | ||
10 | CDKN1A | 4050088 6400706 | 246 | 1.863 | 0.3278 | Yes | ||
11 | TGFBR2 | 1780711 1980537 6550398 | 275 | 1.759 | 0.3538 | Yes | ||
12 | NCDN | 50040 1980739 3520603 | 287 | 1.726 | 0.3802 | Yes | ||
13 | UBQLN1 | 110280 730376 2470133 6590594 | 441 | 1.422 | 0.3941 | Yes | ||
14 | SYTL1 | 510487 | 475 | 1.360 | 0.4136 | Yes | ||
15 | PDGFRB | 6450279 | 682 | 1.078 | 0.4192 | Yes | ||
16 | PKN3 | 2260538 | 717 | 1.052 | 0.4339 | Yes | ||
17 | PADI4 | 1740075 4810441 | 737 | 1.041 | 0.4491 | Yes | ||
18 | CAPNS1 | 3940113 | 1110 | 0.774 | 0.4410 | Yes | ||
19 | ABCA2 | 5050039 | 1162 | 0.745 | 0.4499 | Yes | ||
20 | DCTN2 | 540471 3780717 | 1241 | 0.694 | 0.4565 | Yes | ||
21 | AKT1S1 | 1660048 | 1268 | 0.675 | 0.4657 | Yes | ||
22 | COL27A1 | 1740390 | 1446 | 0.586 | 0.4652 | Yes | ||
23 | RAB3D | 4210253 | 1597 | 0.527 | 0.4653 | Yes | ||
24 | RBBP7 | 430113 450450 2370309 | 1647 | 0.507 | 0.4706 | Yes | ||
25 | MAPK3 | 580161 4780035 | 1667 | 0.499 | 0.4774 | Yes | ||
26 | PSMD2 | 4670706 5050364 | 1687 | 0.492 | 0.4840 | Yes | ||
27 | BLMH | 1410438 | 1742 | 0.474 | 0.4885 | Yes | ||
28 | ADCK4 | 1660180 | 1784 | 0.459 | 0.4935 | Yes | ||
29 | ABHD2 | 4850504 6840010 | 2343 | 0.306 | 0.4680 | No | ||
30 | ABHD4 | 6760450 | 2421 | 0.287 | 0.4683 | No | ||
31 | POLR3E | 380152 | 2456 | 0.279 | 0.4708 | No | ||
32 | AP2A2 | 130082 | 2477 | 0.271 | 0.4740 | No | ||
33 | XPOT | 7050184 | 2747 | 0.206 | 0.4626 | No | ||
34 | HSPB8 | 540563 | 2820 | 0.194 | 0.4617 | No | ||
35 | VIM | 20431 | 2895 | 0.181 | 0.4605 | No | ||
36 | SCRN1 | 6040025 6580019 | 2972 | 0.169 | 0.4591 | No | ||
37 | VAMP5 | 3830300 | 2990 | 0.167 | 0.4607 | No | ||
38 | WNT6 | 4570364 | 3099 | 0.152 | 0.4573 | No | ||
39 | DCN | 510332 5340026 5900711 6550092 | 3104 | 0.151 | 0.4594 | No | ||
40 | PSME4 | 380348 1770131 | 3145 | 0.146 | 0.4595 | No | ||
41 | PSMD12 | 730044 | 3274 | 0.130 | 0.4546 | No | ||
42 | APOBEC1 | 4610022 | 3276 | 0.130 | 0.4566 | No | ||
43 | LTBP3 | 1190162 2650440 6520451 | 3303 | 0.127 | 0.4572 | No | ||
44 | TBC1D17 | 1780450 | 3322 | 0.125 | 0.4581 | No | ||
45 | DTNA | 1340600 1780731 2340278 2850132 | 3603 | 0.100 | 0.4445 | No | ||
46 | PTPRN | 5900577 | 3695 | 0.093 | 0.4410 | No | ||
47 | AK5 | 6290348 | 3758 | 0.090 | 0.4391 | No | ||
48 | FHL3 | 1090369 2650017 | 3777 | 0.088 | 0.4395 | No | ||
49 | ROM1 | 3130685 | 3782 | 0.088 | 0.4406 | No | ||
50 | CYFIP1 | 5690082 | 3922 | 0.080 | 0.4343 | No | ||
51 | NR1D1 | 2360471 770746 6590204 | 3969 | 0.078 | 0.4331 | No | ||
52 | CLSTN3 | 2350685 | 4203 | 0.067 | 0.4215 | No | ||
53 | UBE2C | 6130017 | 4453 | 0.057 | 0.4088 | No | ||
54 | RIT1 | 5390338 | 4504 | 0.055 | 0.4070 | No | ||
55 | MDFI | 6200041 | 4610 | 0.052 | 0.4021 | No | ||
56 | FLNC | 2360048 5050270 | 4791 | 0.046 | 0.3931 | No | ||
57 | PAPPA | 4230463 | 4850 | 0.045 | 0.3906 | No | ||
58 | NEFH | 630239 | 4887 | 0.044 | 0.3894 | No | ||
59 | MARK1 | 450484 | 4977 | 0.042 | 0.3852 | No | ||
60 | HSPB7 | 1190441 | 4982 | 0.042 | 0.3856 | No | ||
61 | LAMC2 | 450692 2680041 4200059 4670148 | 5163 | 0.038 | 0.3764 | No | ||
62 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 5220 | 0.037 | 0.3740 | No | ||
63 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.3623 | No | ||
64 | ADORA2A | 1990687 | 5457 | 0.032 | 0.3622 | No | ||
65 | GPR3 | 2970452 | 5615 | 0.030 | 0.3542 | No | ||
66 | RB1CC1 | 510494 7100072 | 5691 | 0.028 | 0.3506 | No | ||
67 | OLR1 | 50025 3840484 | 5804 | 0.026 | 0.3449 | No | ||
68 | EEF1A2 | 2260162 5290086 | 5826 | 0.026 | 0.3442 | No | ||
69 | RIMS1 | 5670022 | 5901 | 0.025 | 0.3405 | No | ||
70 | SLC16A6 | 1690156 | 6017 | 0.023 | 0.3347 | No | ||
71 | CASK | 2340215 3290576 6770215 | 6245 | 0.021 | 0.3227 | No | ||
72 | APBA2BP | 5700341 | 6248 | 0.021 | 0.3229 | No | ||
73 | XLKD1 | 520441 | 6270 | 0.020 | 0.3221 | No | ||
74 | DIRAS1 | 2640270 | 6284 | 0.020 | 0.3217 | No | ||
75 | SHC3 | 2690398 | 6753 | 0.016 | 0.2966 | No | ||
76 | WDFY3 | 3610041 4560333 4570273 | 7000 | 0.015 | 0.2834 | No | ||
77 | VASP | 7050500 | 7056 | 0.014 | 0.2807 | No | ||
78 | PVALB | 5570450 | 7084 | 0.014 | 0.2794 | No | ||
79 | UCHL3 | 1240735 | 7146 | 0.014 | 0.2763 | No | ||
80 | PTPRH | 3870070 | 7157 | 0.014 | 0.2760 | No | ||
81 | GFAP | 2060092 | 7266 | 0.013 | 0.2703 | No | ||
82 | BTK | 3130044 | 7290 | 0.013 | 0.2693 | No | ||
83 | BMP2 | 6620687 | 7299 | 0.013 | 0.2691 | No | ||
84 | PHLDA2 | 4810494 | 7658 | 0.011 | 0.2498 | No | ||
85 | NRIP3 | 1340372 | 7691 | 0.011 | 0.2482 | No | ||
86 | LPP | 1660541 | 7723 | 0.010 | 0.2467 | No | ||
87 | GGN | 1410528 4210082 5290170 | 7731 | 0.010 | 0.2465 | No | ||
88 | KBTBD5 | 6350025 | 7787 | 0.010 | 0.2437 | No | ||
89 | ST18 | 5720537 | 7789 | 0.010 | 0.2438 | No | ||
90 | DSTN | 3140592 | 7961 | 0.009 | 0.2347 | No | ||
91 | EPHA2 | 5890056 | 7993 | 0.009 | 0.2331 | No | ||
92 | TLL1 | 2680315 | 8101 | 0.009 | 0.2275 | No | ||
93 | TRIB1 | 2320435 | 8178 | 0.008 | 0.2235 | No | ||
94 | SCEL | 3190129 | 8358 | 0.008 | 0.2139 | No | ||
95 | MMP7 | 1780497 | 8376 | 0.008 | 0.2131 | No | ||
96 | IGSF9 | 1770411 | 8396 | 0.008 | 0.2122 | No | ||
97 | P2RXL1 | 4730390 5220446 | 8509 | 0.007 | 0.2062 | No | ||
98 | MYBPH | 2190711 | 8534 | 0.007 | 0.2050 | No | ||
99 | SLC35E4 | 2370711 | 8821 | 0.006 | 0.1896 | No | ||
100 | IL9 | 3440338 | 8982 | 0.006 | 0.1810 | No | ||
101 | IBRDC2 | 5130041 | 9073 | 0.005 | 0.1762 | No | ||
102 | C3AR1 | 5720131 | 9234 | 0.005 | 0.1676 | No | ||
103 | YWHAZ | 1230717 | 9466 | 0.004 | 0.1551 | No | ||
104 | SCOC | 610048 2230053 | 9675 | 0.004 | 0.1439 | No | ||
105 | GAB2 | 1410280 2340520 4280040 | 10137 | 0.002 | 0.1189 | No | ||
106 | IL23A | 6290044 | 10398 | 0.002 | 0.1048 | No | ||
107 | CRYBA2 | 5900138 | 10466 | 0.001 | 0.1012 | No | ||
108 | NR0B2 | 2470692 | 10637 | 0.001 | 0.0920 | No | ||
109 | HOXA11 | 6980133 | 10713 | 0.001 | 0.0880 | No | ||
110 | HOXD3 | 6450154 | 10852 | 0.000 | 0.0805 | No | ||
111 | AP2B1 | 1450184 2370148 3520139 4850593 | 11213 | -0.001 | 0.0610 | No | ||
112 | IL1RN | 2370333 | 11222 | -0.001 | 0.0605 | No | ||
113 | GJB3 | 2650040 | 11235 | -0.001 | 0.0599 | No | ||
114 | USP13 | 1450670 | 11261 | -0.001 | 0.0586 | No | ||
115 | EIF3S1 | 6130368 6770044 | 11330 | -0.001 | 0.0549 | No | ||
116 | UCN2 | 4590372 | 11341 | -0.001 | 0.0544 | No | ||
117 | SYT2 | 60609 | 11396 | -0.001 | 0.0515 | No | ||
118 | SPATS2 | 2360066 | 11409 | -0.001 | 0.0508 | No | ||
119 | SPARC | 1690086 | 11661 | -0.002 | 0.0372 | No | ||
120 | FAP | 4560019 | 11738 | -0.003 | 0.0332 | No | ||
121 | PRDM1 | 3170347 3520301 | 11775 | -0.003 | 0.0313 | No | ||
122 | NFATC4 | 2470735 | 11894 | -0.003 | 0.0249 | No | ||
123 | S100A5 | 4120592 | 11952 | -0.003 | 0.0219 | No | ||
124 | PFTK1 | 1780181 | 11956 | -0.003 | 0.0218 | No | ||
125 | GNAI1 | 4560390 | 12039 | -0.004 | 0.0174 | No | ||
126 | SNCB | 3360133 | 12041 | -0.004 | 0.0174 | No | ||
127 | FGF12 | 1740446 2360037 | 12167 | -0.004 | 0.0106 | No | ||
128 | COBL | 2480452 6110066 | 12314 | -0.005 | 0.0028 | No | ||
129 | ANXA7 | 6110446 | 12470 | -0.005 | -0.0055 | No | ||
130 | PTP4A1 | 130692 | 12489 | -0.005 | -0.0064 | No | ||
131 | OMG | 6760066 | 12551 | -0.006 | -0.0096 | No | ||
132 | SLC26A1 | 2190142 | 12607 | -0.006 | -0.0125 | No | ||
133 | DSCR1L1 | 940438 | 12848 | -0.007 | -0.0254 | No | ||
134 | SFTPC | 3290133 | 12950 | -0.008 | -0.0308 | No | ||
135 | TRPV3 | 540341 | 13046 | -0.008 | -0.0358 | No | ||
136 | FBXW11 | 6450632 | 13100 | -0.009 | -0.0386 | No | ||
137 | IDS | 360619 5720161 | 13329 | -0.011 | -0.0508 | No | ||
138 | PDAP1 | 1410735 | 13468 | -0.012 | -0.0581 | No | ||
139 | PCDH9 | 2100136 | 13555 | -0.013 | -0.0625 | No | ||
140 | EFNA1 | 3840672 | 13813 | -0.016 | -0.0762 | No | ||
141 | DHRS3 | 360609 | 13924 | -0.018 | -0.0819 | No | ||
142 | STAT5B | 6200026 | 13947 | -0.018 | -0.0828 | No | ||
143 | ROCK2 | 1780035 5720025 | 14035 | -0.019 | -0.0872 | No | ||
144 | KCNA2 | 5080403 | 14158 | -0.022 | -0.0935 | No | ||
145 | LRRFIP2 | 670575 730152 6590438 | 14179 | -0.022 | -0.0943 | No | ||
146 | GPX1 | 4150093 | 14266 | -0.024 | -0.0985 | No | ||
147 | NEK6 | 3360687 | 14470 | -0.031 | -0.1091 | No | ||
148 | PEA15 | 4590685 | 14571 | -0.034 | -0.1140 | No | ||
149 | PLCD1 | 2030484 | 14591 | -0.035 | -0.1144 | No | ||
150 | RIN1 | 510593 | 14721 | -0.042 | -0.1208 | No | ||
151 | SFN | 6290301 7510608 | 14794 | -0.046 | -0.1240 | No | ||
152 | STX17 | 2260037 | 14948 | -0.054 | -0.1314 | No | ||
153 | HDAC3 | 4060072 | 14956 | -0.055 | -0.1310 | No | ||
154 | VDR | 130156 510438 | 14991 | -0.057 | -0.1319 | No | ||
155 | PSMD11 | 2340538 6510053 | 15030 | -0.059 | -0.1331 | No | ||
156 | ITPKC | 5420021 | 15077 | -0.063 | -0.1346 | No | ||
157 | MAP1A | 4920576 | 15089 | -0.064 | -0.1342 | No | ||
158 | PKP3 | 3710048 | 15121 | -0.066 | -0.1348 | No | ||
159 | ABCD1 | 5670373 | 15194 | -0.071 | -0.1376 | No | ||
160 | EIF4E | 1580403 70133 6380215 | 15566 | -0.108 | -0.1560 | No | ||
161 | LAMA3 | 1190131 5290239 | 15581 | -0.109 | -0.1551 | No | ||
162 | PITPNC1 | 3990017 | 15889 | -0.147 | -0.1695 | No | ||
163 | ICK | 1580746 3140021 | 15946 | -0.156 | -0.1700 | No | ||
164 | LAPTM5 | 5550372 | 15974 | -0.160 | -0.1690 | No | ||
165 | NFRKB | 3130538 | 16188 | -0.195 | -0.1775 | No | ||
166 | GTF2B | 6860685 | 16494 | -0.263 | -0.1900 | No | ||
167 | PSMD4 | 430068 | 16588 | -0.287 | -0.1905 | No | ||
168 | MCART1 | 5270059 | 16634 | -0.301 | -0.1882 | No | ||
169 | AXIN2 | 3850131 | 16873 | -0.371 | -0.1953 | No | ||
170 | PSMD7 | 2030619 6220594 | 16931 | -0.389 | -0.1924 | No | ||
171 | BAZ2A | 730184 | 17111 | -0.455 | -0.1949 | No | ||
172 | MMP9 | 580338 | 17451 | -0.607 | -0.2039 | No | ||
173 | CMAS | 2190129 | 17841 | -0.842 | -0.2118 | No | ||
174 | GADD45A | 2900717 | 17927 | -0.915 | -0.2021 | No | ||
175 | TRIM8 | 6130441 | 18037 | -1.028 | -0.1919 | No | ||
176 | CAMKK1 | 6370324 | 18155 | -1.198 | -0.1795 | No | ||
177 | TRAF3 | 5690647 | 18205 | -1.269 | -0.1624 | No | ||
178 | LAMC1 | 4730025 | 18218 | -1.300 | -0.1427 | No | ||
179 | TCF12 | 3610324 7000156 | 18220 | -1.303 | -0.1224 | No | ||
180 | TMEM24 | 5860039 | 18279 | -1.427 | -0.1032 | No | ||
181 | PPP2CA | 3990113 | 18280 | -1.429 | -0.0809 | No | ||
182 | ATP1B1 | 3130594 | 18366 | -1.702 | -0.0589 | No | ||
183 | ABI3 | 1740563 | 18435 | -1.873 | -0.0333 | No | ||
184 | ELK3 | 460377 1400762 3710497 | 18570 | -2.752 | 0.0025 | No |