Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q4 |
Enrichment Score (ES) | 0.5241468 |
Normalized Enrichment Score (NES) | 1.3064874 |
Nominal p-value | 0.021770682 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EEF1A1 | 1980193 1990195 4670735 | 2 | 8.490 | 0.0998 | Yes | ||
2 | RPL27A | 3130451 110195 6840494 | 3 | 8.163 | 0.1959 | Yes | ||
3 | TCF7 | 3800736 5390181 | 60 | 3.131 | 0.2297 | Yes | ||
4 | CIZ1 | 4150128 6130484 | 106 | 2.553 | 0.2573 | Yes | ||
5 | LMNA | 520471 1500075 3190167 4210020 | 152 | 2.286 | 0.2818 | Yes | ||
6 | CD151 | 1450592 3780309 | 170 | 2.194 | 0.3067 | Yes | ||
7 | ELA1 | 3390167 | 189 | 2.067 | 0.3300 | Yes | ||
8 | TAGLN2 | 4560121 | 221 | 1.943 | 0.3512 | Yes | ||
9 | ETV5 | 110017 | 222 | 1.935 | 0.3740 | Yes | ||
10 | RTN4 | 50725 630647 870097 870184 | 236 | 1.892 | 0.3955 | Yes | ||
11 | CDKN1A | 4050088 6400706 | 246 | 1.863 | 0.4170 | Yes | ||
12 | TGFBR2 | 1780711 1980537 6550398 | 275 | 1.759 | 0.4362 | Yes | ||
13 | UBQLN1 | 110280 730376 2470133 6590594 | 441 | 1.422 | 0.4439 | Yes | ||
14 | SYTL1 | 510487 | 475 | 1.360 | 0.4582 | Yes | ||
15 | ABCB6 | 6350138 | 509 | 1.319 | 0.4719 | Yes | ||
16 | PDGFRB | 6450279 | 682 | 1.078 | 0.4752 | Yes | ||
17 | PKN3 | 2260538 | 717 | 1.052 | 0.4858 | Yes | ||
18 | BAG2 | 2900324 | 851 | 0.951 | 0.4898 | Yes | ||
19 | DTX2 | 4210041 7000008 | 885 | 0.928 | 0.4989 | Yes | ||
20 | CAPNS1 | 3940113 | 1110 | 0.774 | 0.4958 | Yes | ||
21 | LIMK1 | 5080064 | 1220 | 0.704 | 0.4982 | Yes | ||
22 | DCTN2 | 540471 3780717 | 1241 | 0.694 | 0.5053 | Yes | ||
23 | AKT1S1 | 1660048 | 1268 | 0.675 | 0.5118 | Yes | ||
24 | COL27A1 | 1740390 | 1446 | 0.586 | 0.5091 | Yes | ||
25 | GNGT2 | 540176 | 1460 | 0.580 | 0.5152 | Yes | ||
26 | TNFRSF12A | 4810253 | 1513 | 0.557 | 0.5190 | Yes | ||
27 | RBBP7 | 430113 450450 2370309 | 1647 | 0.507 | 0.5177 | Yes | ||
28 | MAPK3 | 580161 4780035 | 1667 | 0.499 | 0.5226 | Yes | ||
29 | BLMH | 1410438 | 1742 | 0.474 | 0.5241 | Yes | ||
30 | FKBP8 | 4060019 | 1855 | 0.439 | 0.5232 | No | ||
31 | CORO1C | 4570397 | 2058 | 0.379 | 0.5167 | No | ||
32 | ABHD2 | 4850504 6840010 | 2343 | 0.306 | 0.5049 | No | ||
33 | ABHD4 | 6760450 | 2421 | 0.287 | 0.5041 | No | ||
34 | POLR3E | 380152 | 2456 | 0.279 | 0.5056 | No | ||
35 | AP2A2 | 130082 | 2477 | 0.271 | 0.5077 | No | ||
36 | STOML2 | 1940487 | 2746 | 0.206 | 0.4955 | No | ||
37 | XPOT | 7050184 | 2747 | 0.206 | 0.4980 | No | ||
38 | IGFBP6 | 1580181 | 2757 | 0.203 | 0.4999 | No | ||
39 | MMP19 | 5080377 | 2811 | 0.195 | 0.4993 | No | ||
40 | LAMB3 | 7100301 | 2852 | 0.189 | 0.4993 | No | ||
41 | IRAK1 | 4120593 | 2873 | 0.185 | 0.5004 | No | ||
42 | VIM | 20431 | 2895 | 0.181 | 0.5014 | No | ||
43 | SCRN1 | 6040025 6580019 | 2972 | 0.169 | 0.4993 | No | ||
44 | APOBEC1 | 4610022 | 3276 | 0.130 | 0.4844 | No | ||
45 | LTBP3 | 1190162 2650440 6520451 | 3303 | 0.127 | 0.4845 | No | ||
46 | TBC1D17 | 1780450 | 3322 | 0.125 | 0.4850 | No | ||
47 | IL10 | 2340685 2640541 2850403 6590286 | 3356 | 0.121 | 0.4846 | No | ||
48 | DUSP13 | 6400152 | 3645 | 0.098 | 0.4701 | No | ||
49 | PTPRN | 5900577 | 3695 | 0.093 | 0.4685 | No | ||
50 | AK5 | 6290348 | 3758 | 0.090 | 0.4662 | No | ||
51 | FHL3 | 1090369 2650017 | 3777 | 0.088 | 0.4663 | No | ||
52 | ROM1 | 3130685 | 3782 | 0.088 | 0.4671 | No | ||
53 | CYFIP1 | 5690082 | 3922 | 0.080 | 0.4605 | No | ||
54 | CLSTN3 | 2350685 | 4203 | 0.067 | 0.4461 | No | ||
55 | NRAS | 6900577 | 4430 | 0.057 | 0.4345 | No | ||
56 | UBE2C | 6130017 | 4453 | 0.057 | 0.4340 | No | ||
57 | MDFI | 6200041 | 4610 | 0.052 | 0.4261 | No | ||
58 | GSN | 3830168 | 4778 | 0.047 | 0.4176 | No | ||
59 | PAPPA | 4230463 | 4850 | 0.045 | 0.4143 | No | ||
60 | NEFH | 630239 | 4887 | 0.044 | 0.4129 | No | ||
61 | HSPB7 | 1190441 | 4982 | 0.042 | 0.4083 | No | ||
62 | LAMC2 | 450692 2680041 4200059 4670148 | 5163 | 0.038 | 0.3989 | No | ||
63 | KCNN4 | 2680129 | 5218 | 0.037 | 0.3964 | No | ||
64 | TIAL1 | 4150048 6510605 | 5446 | 0.032 | 0.3845 | No | ||
65 | ADORA2A | 1990687 | 5457 | 0.032 | 0.3843 | No | ||
66 | GPR150 | 2570440 | 5490 | 0.031 | 0.3830 | No | ||
67 | GPR3 | 2970452 | 5615 | 0.030 | 0.3766 | No | ||
68 | RB1CC1 | 510494 7100072 | 5691 | 0.028 | 0.3729 | No | ||
69 | EEF1A2 | 2260162 5290086 | 5826 | 0.026 | 0.3659 | No | ||
70 | ESRRB | 3870082 | 5850 | 0.026 | 0.3650 | No | ||
71 | DNM1 | 1660097 5340519 | 5933 | 0.025 | 0.3608 | No | ||
72 | SLC16A6 | 1690156 | 6017 | 0.023 | 0.3566 | No | ||
73 | ZIC1 | 670113 | 6083 | 0.023 | 0.3533 | No | ||
74 | CASK | 2340215 3290576 6770215 | 6245 | 0.021 | 0.3448 | No | ||
75 | APBA2BP | 5700341 | 6248 | 0.021 | 0.3449 | No | ||
76 | XLKD1 | 520441 | 6270 | 0.020 | 0.3440 | No | ||
77 | PLAC1 | 2350594 | 6298 | 0.020 | 0.3428 | No | ||
78 | PAX9 | 3850519 | 6541 | 0.018 | 0.3299 | No | ||
79 | SHC3 | 2690398 | 6753 | 0.016 | 0.3187 | No | ||
80 | CCL22 | 6380086 | 6862 | 0.016 | 0.3130 | No | ||
81 | WDFY3 | 3610041 4560333 4570273 | 7000 | 0.015 | 0.3057 | No | ||
82 | UCHL3 | 1240735 | 7146 | 0.014 | 0.2980 | No | ||
83 | PTPRH | 3870070 | 7157 | 0.014 | 0.2976 | No | ||
84 | MAPRE3 | 7050504 | 7209 | 0.013 | 0.2950 | No | ||
85 | BTK | 3130044 | 7290 | 0.013 | 0.2908 | No | ||
86 | BMP2 | 6620687 | 7299 | 0.013 | 0.2905 | No | ||
87 | APOB48R | 2810070 | 7306 | 0.013 | 0.2904 | No | ||
88 | SH3RF2 | 6200600 | 7361 | 0.012 | 0.2876 | No | ||
89 | PTPRR | 130121 3990273 | 7400 | 0.012 | 0.2857 | No | ||
90 | EYA1 | 1450278 5220390 | 7412 | 0.012 | 0.2852 | No | ||
91 | LRP1B | 1450193 | 7555 | 0.011 | 0.2776 | No | ||
92 | NRIP3 | 1340372 | 7691 | 0.011 | 0.2704 | No | ||
93 | LPP | 1660541 | 7723 | 0.010 | 0.2689 | No | ||
94 | GGN | 1410528 4210082 5290170 | 7731 | 0.010 | 0.2686 | No | ||
95 | KBTBD5 | 6350025 | 7787 | 0.010 | 0.2658 | No | ||
96 | ST18 | 5720537 | 7789 | 0.010 | 0.2658 | No | ||
97 | DSTN | 3140592 | 7961 | 0.009 | 0.2567 | No | ||
98 | EPHA2 | 5890056 | 7993 | 0.009 | 0.2551 | No | ||
99 | TRIB1 | 2320435 | 8178 | 0.008 | 0.2452 | No | ||
100 | MMP7 | 1780497 | 8376 | 0.008 | 0.2346 | No | ||
101 | CMYA1 | 6900632 | 8400 | 0.008 | 0.2334 | No | ||
102 | LIFR | 3360068 3830102 | 8437 | 0.008 | 0.2316 | No | ||
103 | MYBPH | 2190711 | 8534 | 0.007 | 0.2265 | No | ||
104 | PADI3 | 6520072 | 8936 | 0.006 | 0.2048 | No | ||
105 | IL9 | 3440338 | 8982 | 0.006 | 0.2024 | No | ||
106 | IBRDC2 | 5130041 | 9073 | 0.005 | 0.1976 | No | ||
107 | SCOC | 610048 2230053 | 9675 | 0.004 | 0.1650 | No | ||
108 | GAB2 | 1410280 2340520 4280040 | 10137 | 0.002 | 0.1400 | No | ||
109 | BNIP3 | 3140270 | 10327 | 0.002 | 0.1298 | No | ||
110 | IL23A | 6290044 | 10398 | 0.002 | 0.1260 | No | ||
111 | CRYBA2 | 5900138 | 10466 | 0.001 | 0.1224 | No | ||
112 | FGF11 | 840292 | 10594 | 0.001 | 0.1155 | No | ||
113 | HOXA11 | 6980133 | 10713 | 0.001 | 0.1091 | No | ||
114 | HOXD3 | 6450154 | 10852 | 0.000 | 0.1016 | No | ||
115 | AP2B1 | 1450184 2370148 3520139 4850593 | 11213 | -0.001 | 0.0821 | No | ||
116 | IL1RN | 2370333 | 11222 | -0.001 | 0.0817 | No | ||
117 | GJB3 | 2650040 | 11235 | -0.001 | 0.0810 | No | ||
118 | AKAP1 | 110148 1740735 2260019 7000563 | 11256 | -0.001 | 0.0800 | No | ||
119 | USP13 | 1450670 | 11261 | -0.001 | 0.0798 | No | ||
120 | EIF3S1 | 6130368 6770044 | 11330 | -0.001 | 0.0761 | No | ||
121 | UCN2 | 4590372 | 11341 | -0.001 | 0.0755 | No | ||
122 | FAP | 4560019 | 11738 | -0.003 | 0.0541 | No | ||
123 | PRDM1 | 3170347 3520301 | 11775 | -0.003 | 0.0522 | No | ||
124 | S100A5 | 4120592 | 11952 | -0.003 | 0.0427 | No | ||
125 | GNAI1 | 4560390 | 12039 | -0.004 | 0.0380 | No | ||
126 | FGF12 | 1740446 2360037 | 12167 | -0.004 | 0.0312 | No | ||
127 | EDN1 | 1770047 | 12188 | -0.004 | 0.0302 | No | ||
128 | ANXA7 | 6110446 | 12470 | -0.005 | 0.0150 | No | ||
129 | GOLGA4 | 460300 | 12487 | -0.005 | 0.0142 | No | ||
130 | UBE3A | 1240152 2690438 5860609 | 12858 | -0.007 | -0.0058 | No | ||
131 | TRPV3 | 540341 | 13046 | -0.008 | -0.0159 | No | ||
132 | FBXW11 | 6450632 | 13100 | -0.009 | -0.0186 | No | ||
133 | EVI2B | 1050465 | 13339 | -0.011 | -0.0314 | No | ||
134 | RAD23B | 2190671 | 13348 | -0.011 | -0.0317 | No | ||
135 | IL6 | 380133 | 13456 | -0.012 | -0.0374 | No | ||
136 | PDAP1 | 1410735 | 13468 | -0.012 | -0.0379 | No | ||
137 | PCDH9 | 2100136 | 13555 | -0.013 | -0.0424 | No | ||
138 | EFNA1 | 3840672 | 13813 | -0.016 | -0.0561 | No | ||
139 | PDE4D | 2470528 6660014 | 13911 | -0.017 | -0.0612 | No | ||
140 | STAT5B | 6200026 | 13947 | -0.018 | -0.0629 | No | ||
141 | ROCK2 | 1780035 5720025 | 14035 | -0.019 | -0.0674 | No | ||
142 | RABEP1 | 4760427 6200463 | 14076 | -0.020 | -0.0693 | No | ||
143 | LRRC15 | 3940609 | 14134 | -0.021 | -0.0721 | No | ||
144 | LRRFIP2 | 670575 730152 6590438 | 14179 | -0.022 | -0.0743 | No | ||
145 | NEK6 | 3360687 | 14470 | -0.031 | -0.0896 | No | ||
146 | HS3ST3B1 | 380040 | 14701 | -0.041 | -0.1016 | No | ||
147 | RIN1 | 510593 | 14721 | -0.042 | -0.1022 | No | ||
148 | SFN | 6290301 7510608 | 14794 | -0.046 | -0.1056 | No | ||
149 | STX17 | 2260037 | 14948 | -0.054 | -0.1132 | No | ||
150 | HDAC3 | 4060072 | 14956 | -0.055 | -0.1130 | No | ||
151 | VDR | 130156 510438 | 14991 | -0.057 | -0.1141 | No | ||
152 | PSMD11 | 2340538 6510053 | 15030 | -0.059 | -0.1155 | No | ||
153 | MAP1A | 4920576 | 15089 | -0.064 | -0.1179 | No | ||
154 | MAP2K1 | 840739 | 15475 | -0.098 | -0.1376 | No | ||
155 | EIF4E | 1580403 70133 6380215 | 15566 | -0.108 | -0.1412 | No | ||
156 | AKT3 | 1580270 3290278 | 15756 | -0.129 | -0.1500 | No | ||
157 | PITPNC1 | 3990017 | 15889 | -0.147 | -0.1554 | No | ||
158 | ZIC4 | 1500082 | 15904 | -0.148 | -0.1544 | No | ||
159 | ICK | 1580746 3140021 | 15946 | -0.156 | -0.1548 | No | ||
160 | LAPTM5 | 5550372 | 15974 | -0.160 | -0.1544 | No | ||
161 | USP2 | 1190292 1240253 4850035 | 16094 | -0.176 | -0.1588 | No | ||
162 | EIF4G1 | 4070446 | 16118 | -0.180 | -0.1579 | No | ||
163 | NFRKB | 3130538 | 16188 | -0.195 | -0.1593 | No | ||
164 | CREM | 840156 6380438 6660041 6660168 | 16266 | -0.211 | -0.1610 | No | ||
165 | PSMD4 | 430068 | 16588 | -0.287 | -0.1751 | No | ||
166 | MCART1 | 5270059 | 16634 | -0.301 | -0.1740 | No | ||
167 | BACH1 | 290195 | 16764 | -0.337 | -0.1770 | No | ||
168 | AXIN2 | 3850131 | 16873 | -0.371 | -0.1785 | No | ||
169 | USP3 | 2060332 | 16955 | -0.399 | -0.1782 | No | ||
170 | ARRDC4 | 2810019 | 17063 | -0.436 | -0.1789 | No | ||
171 | BAZ2A | 730184 | 17111 | -0.455 | -0.1761 | No | ||
172 | PIM2 | 840136 5720692 7100577 | 17357 | -0.561 | -0.1827 | No | ||
173 | MMP9 | 580338 | 17451 | -0.607 | -0.1806 | No | ||
174 | ISG20 | 1770750 | 17528 | -0.646 | -0.1772 | No | ||
175 | SRPK2 | 6380341 | 17799 | -0.805 | -0.1823 | No | ||
176 | CMAS | 2190129 | 17841 | -0.842 | -0.1747 | No | ||
177 | RPA3 | 5700136 | 17876 | -0.871 | -0.1662 | No | ||
178 | TRIM8 | 6130441 | 18037 | -1.028 | -0.1628 | No | ||
179 | PPP1R9B | 3130619 | 18136 | -1.173 | -0.1543 | No | ||
180 | CAMKK1 | 6370324 | 18155 | -1.198 | -0.1412 | No | ||
181 | LAMC1 | 4730025 | 18218 | -1.300 | -0.1293 | No | ||
182 | TCF12 | 3610324 7000156 | 18220 | -1.303 | -0.1140 | No | ||
183 | ABI3 | 1740563 | 18435 | -1.873 | -0.1036 | No | ||
184 | KCNH2 | 1170451 | 18487 | -2.154 | -0.0810 | No | ||
185 | ELK3 | 460377 1400762 3710497 | 18570 | -2.752 | -0.0530 | No | ||
186 | PSMA3 | 5900047 7040161 | 18612 | -4.714 | 0.0002 | No |