Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | -0.6800335 |
Normalized Enrichment Score (NES) | -1.818472 |
Nominal p-value | 0.0 |
FDR q-value | 0.0043965 |
FWER p-Value | 0.0020 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | OTUB1 | 610551 | 648 | 1.126 | -0.0203 | No | ||
2 | DAB2IP | 3170064 6200441 | 688 | 1.074 | -0.0082 | No | ||
3 | SLC25A26 | 4210577 | 698 | 1.064 | 0.0055 | No | ||
4 | SNRP70 | 4200181 | 714 | 1.053 | 0.0186 | No | ||
5 | CARM1 | 7040292 | 860 | 0.945 | 0.0233 | No | ||
6 | PMP22 | 4010239 6550072 | 1383 | 0.615 | 0.0030 | No | ||
7 | CHKB | 770129 | 1445 | 0.586 | 0.0075 | No | ||
8 | SPIRE2 | 450088 | 1624 | 0.517 | 0.0047 | No | ||
9 | ATP5A1 | 1990722 | 1730 | 0.479 | 0.0053 | No | ||
10 | ANTXR1 | 1990593 2850056 | 1929 | 0.421 | 0.0002 | No | ||
11 | ETF1 | 6770075 | 1978 | 0.402 | 0.0029 | No | ||
12 | DDX3X | 2190020 | 2105 | 0.368 | 0.0009 | No | ||
13 | TMEM16D | 2650324 | 2829 | 0.192 | -0.0359 | No | ||
14 | EFNA3 | 6370390 | 2848 | 0.189 | -0.0343 | No | ||
15 | TRPS1 | 870100 | 3008 | 0.165 | -0.0408 | No | ||
16 | PBX3 | 1300424 3710577 6180575 | 3041 | 0.161 | -0.0404 | No | ||
17 | MADD | 6100725 7000088 | 3137 | 0.147 | -0.0436 | No | ||
18 | TTC7B | 4760725 | 3178 | 0.142 | -0.0439 | No | ||
19 | KPNA4 | 510369 | 3351 | 0.122 | -0.0516 | No | ||
20 | PPP2R5D | 4010156 380408 5550112 5670162 | 3414 | 0.116 | -0.0535 | No | ||
21 | ZMYND19 | 1570706 6860551 | 3459 | 0.113 | -0.0544 | No | ||
22 | SPRYD3 | 50403 | 3563 | 0.103 | -0.0586 | No | ||
23 | GTF2IRD1 | 2030154 3990040 5080372 | 3646 | 0.097 | -0.0618 | No | ||
24 | PPP2R5C | 3310121 6650672 | 3703 | 0.092 | -0.0636 | No | ||
25 | AK5 | 6290348 | 3758 | 0.090 | -0.0653 | No | ||
26 | PFN2 | 730040 5700026 | 3882 | 0.082 | -0.0709 | No | ||
27 | KIF1B | 1240494 2370139 4570270 6510102 | 3987 | 0.077 | -0.0756 | No | ||
28 | ARFGEF1 | 6760494 | 4109 | 0.071 | -0.0812 | No | ||
29 | MAST1 | 6940215 | 4132 | 0.070 | -0.0815 | No | ||
30 | DHX36 | 2470465 | 4212 | 0.066 | -0.0849 | No | ||
31 | ATAD2 | 870242 2260687 | 4269 | 0.064 | -0.0871 | No | ||
32 | NDST1 | 1500427 5340121 | 4322 | 0.061 | -0.0891 | No | ||
33 | VPS13D | 2350451 | 4323 | 0.061 | -0.0883 | No | ||
34 | TBC1D4 | 6420397 | 4335 | 0.060 | -0.0881 | No | ||
35 | SNAI1 | 6590253 | 4581 | 0.053 | -0.1007 | No | ||
36 | SOX21 | 1050110 4670041 6660338 | 4588 | 0.053 | -0.1003 | No | ||
37 | SDC2 | 1980168 | 4688 | 0.050 | -0.1050 | No | ||
38 | HIVEP2 | 6520538 | 4690 | 0.050 | -0.1044 | No | ||
39 | OVOL1 | 1690131 | 4812 | 0.046 | -0.1104 | No | ||
40 | ENAH | 1690292 5700300 | 4871 | 0.044 | -0.1130 | No | ||
41 | GABRG2 | 2350402 4210204 6130279 6550037 | 4890 | 0.044 | -0.1134 | No | ||
42 | SEMA4C | 1980315 | 4942 | 0.042 | -0.1156 | No | ||
43 | GAD1 | 2360035 3140167 | 4956 | 0.042 | -0.1157 | No | ||
44 | MARK1 | 450484 | 4977 | 0.042 | -0.1163 | No | ||
45 | VAMP2 | 2100100 | 5047 | 0.040 | -0.1195 | No | ||
46 | CITED2 | 5670114 5130088 | 5161 | 0.038 | -0.1251 | No | ||
47 | SPAG8 | 4280446 | 5391 | 0.034 | -0.1371 | No | ||
48 | NXPH1 | 3870546 | 5525 | 0.031 | -0.1439 | No | ||
49 | TRAM2 | 3940112 | 5565 | 0.030 | -0.1457 | No | ||
50 | TTN | 2320161 4670056 6550026 | 5592 | 0.030 | -0.1467 | No | ||
51 | WNT5A | 840685 3120152 | 5922 | 0.025 | -0.1642 | No | ||
52 | NMT1 | 5810152 | 6043 | 0.023 | -0.1705 | No | ||
53 | FZD4 | 1580520 | 6076 | 0.023 | -0.1719 | No | ||
54 | ZIC1 | 670113 | 6083 | 0.023 | -0.1719 | No | ||
55 | FHOD3 | 1240541 | 6150 | 0.022 | -0.1752 | No | ||
56 | CDH13 | 5130368 5340114 | 6175 | 0.022 | -0.1762 | No | ||
57 | SRPX | 580717 1980162 | 6238 | 0.021 | -0.1793 | No | ||
58 | UNC5A | 2120528 3060324 | 6268 | 0.020 | -0.1806 | No | ||
59 | CDH11 | 1230133 2100180 4610110 | 6354 | 0.020 | -0.1850 | No | ||
60 | GABRA1 | 130372 | 6482 | 0.019 | -0.1917 | No | ||
61 | COBLL1 | 4230056 6370494 | 6548 | 0.018 | -0.1949 | No | ||
62 | PDGFC | 4200133 | 6561 | 0.018 | -0.1954 | No | ||
63 | SALL1 | 5420020 7050195 | 6705 | 0.017 | -0.2029 | No | ||
64 | SORCS3 | 5700309 | 6864 | 0.016 | -0.2113 | No | ||
65 | WDFY3 | 3610041 4560333 4570273 | 7000 | 0.015 | -0.2184 | No | ||
66 | PSD2 | 2060091 | 7069 | 0.014 | -0.2219 | No | ||
67 | NLGN3 | 2650463 | 7077 | 0.014 | -0.2221 | No | ||
68 | SH2D3C | 3060014 | 7207 | 0.013 | -0.2290 | No | ||
69 | PIK3R1 | 4730671 | 7321 | 0.013 | -0.2349 | No | ||
70 | CDH2 | 520435 2450451 2760025 6650477 | 7351 | 0.012 | -0.2364 | No | ||
71 | DCUN1D1 | 2360332 | 7372 | 0.012 | -0.2373 | No | ||
72 | EYA1 | 1450278 5220390 | 7412 | 0.012 | -0.2392 | No | ||
73 | ESRRG | 4010181 | 7822 | 0.010 | -0.2613 | No | ||
74 | IL1A | 3610056 | 8005 | 0.009 | -0.2711 | No | ||
75 | CAPN3 | 1980451 6940047 | 8217 | 0.008 | -0.2825 | No | ||
76 | IRF7 | 1570605 | 8258 | 0.008 | -0.2845 | No | ||
77 | JPH1 | 610739 | 8475 | 0.007 | -0.2962 | No | ||
78 | CPNE8 | 7040039 | 8836 | 0.006 | -0.3157 | No | ||
79 | POU4F1 | 2260315 | 8938 | 0.006 | -0.3211 | No | ||
80 | BHLHB3 | 3450438 | 9088 | 0.005 | -0.3291 | No | ||
81 | SERTAD2 | 2810673 6840450 | 9291 | 0.005 | -0.3400 | No | ||
82 | GPC4 | 5910408 | 9341 | 0.004 | -0.3426 | No | ||
83 | UNC50 | 4920037 | 9349 | 0.004 | -0.3430 | No | ||
84 | EIF2C1 | 6900551 | 9369 | 0.004 | -0.3439 | No | ||
85 | ZBTB11 | 6520092 | 9411 | 0.004 | -0.3461 | No | ||
86 | BHLHB5 | 6510520 | 9463 | 0.004 | -0.3488 | No | ||
87 | ADAM10 | 3780156 | 9517 | 0.004 | -0.3517 | No | ||
88 | DKK2 | 3610433 | 9536 | 0.004 | -0.3526 | No | ||
89 | DLL1 | 1770377 | 9609 | 0.004 | -0.3564 | No | ||
90 | ARID1A | 2630022 1690551 4810110 | 9720 | 0.003 | -0.3624 | No | ||
91 | NRXN3 | 1400546 3360471 | 9768 | 0.003 | -0.3649 | No | ||
92 | LRRTM3 | 4210021 | 10217 | 0.002 | -0.3892 | No | ||
93 | PCDH18 | 430010 | 10284 | 0.002 | -0.3928 | No | ||
94 | ZIC2 | 1410408 | 10312 | 0.002 | -0.3942 | No | ||
95 | FIGN | 7000601 | 10364 | 0.002 | -0.3970 | No | ||
96 | MEF2C | 670025 780338 | 10376 | 0.002 | -0.3976 | No | ||
97 | SS18 | 1940440 2900072 6900129 | 10506 | 0.001 | -0.4046 | No | ||
98 | TMEFF1 | 2680100 | 10541 | 0.001 | -0.4064 | No | ||
99 | EPHA7 | 1190288 4010278 | 10549 | 0.001 | -0.4067 | No | ||
100 | BCOR | 1660452 3940053 | 10650 | 0.001 | -0.4122 | No | ||
101 | RPE | 940114 | 10766 | 0.000 | -0.4184 | No | ||
102 | GABRA5 | 5570215 | 11095 | -0.001 | -0.4362 | No | ||
103 | KCNMA1 | 1450402 | 11150 | -0.001 | -0.4392 | No | ||
104 | RSBN1 | 7000487 | 11194 | -0.001 | -0.4415 | No | ||
105 | SV2B | 3850717 | 11388 | -0.001 | -0.4520 | No | ||
106 | RIMS3 | 3890563 | 11414 | -0.001 | -0.4533 | No | ||
107 | CUL5 | 450142 | 12053 | -0.004 | -0.4879 | No | ||
108 | CCNT2 | 2100390 4150563 | 12113 | -0.004 | -0.4911 | No | ||
109 | SP3 | 3840338 | 12266 | -0.004 | -0.4993 | No | ||
110 | NLGN1 | 5670278 | 12288 | -0.005 | -0.5004 | No | ||
111 | HEMGN | 670411 | 12372 | -0.005 | -0.5048 | No | ||
112 | RALGPS1 | 3440129 6400746 | 12414 | -0.005 | -0.5070 | No | ||
113 | GRM5 | 60528 | 12421 | -0.005 | -0.5072 | No | ||
114 | KCNIP4 | 4120435 7050605 | 12427 | -0.005 | -0.5075 | No | ||
115 | AR | 6380167 | 12553 | -0.006 | -0.5142 | No | ||
116 | ARHGAP5 | 2510619 3360035 | 12685 | -0.006 | -0.5212 | No | ||
117 | UBE3A | 1240152 2690438 5860609 | 12858 | -0.007 | -0.5305 | No | ||
118 | DACH1 | 2450593 5700592 | 12888 | -0.007 | -0.5319 | No | ||
119 | CSNK1A1 | 2340427 | 13201 | -0.009 | -0.5488 | No | ||
120 | BASP1 | 5700044 | 13314 | -0.011 | -0.5547 | No | ||
121 | OSBPL6 | 3800072 | 13479 | -0.012 | -0.5635 | No | ||
122 | USP21 | 3060446 | 13561 | -0.013 | -0.5677 | No | ||
123 | PDZRN3 | 2340131 | 13625 | -0.013 | -0.5710 | No | ||
124 | RBBP6 | 2320129 | 13716 | -0.015 | -0.5757 | No | ||
125 | JUN | 840170 | 13846 | -0.016 | -0.5825 | No | ||
126 | PUM2 | 4200441 5910446 | 13875 | -0.017 | -0.5838 | No | ||
127 | UBE2V2 | 4210484 | 13881 | -0.017 | -0.5838 | No | ||
128 | PDE4D | 2470528 6660014 | 13911 | -0.017 | -0.5851 | No | ||
129 | PCGF2 | 6370347 | 13929 | -0.018 | -0.5858 | No | ||
130 | SNX9 | 3290592 | 14223 | -0.023 | -0.6015 | No | ||
131 | PIP5K3 | 5360112 | 14234 | -0.023 | -0.6017 | No | ||
132 | IRX3 | 4200112 | 14354 | -0.027 | -0.6078 | No | ||
133 | TNFSF11 | 6350204 | 14396 | -0.028 | -0.6097 | No | ||
134 | CUGBP2 | 6180121 6840139 | 14416 | -0.028 | -0.6103 | No | ||
135 | CRSP6 | 2940358 | 14504 | -0.032 | -0.6146 | No | ||
136 | CDC14A | 4050132 | 14547 | -0.033 | -0.6165 | No | ||
137 | TJP1 | 6350184 | 14548 | -0.033 | -0.6160 | No | ||
138 | SPRED2 | 510138 540195 | 14681 | -0.039 | -0.6227 | No | ||
139 | HS3ST3B1 | 380040 | 14701 | -0.041 | -0.6232 | No | ||
140 | ANKRD17 | 2120402 3850035 6400044 | 14765 | -0.044 | -0.6260 | No | ||
141 | PTPN12 | 2030309 6020725 6130746 6290609 | 14883 | -0.051 | -0.6317 | No | ||
142 | RBM12 | 4570239 6040411 6660129 | 14903 | -0.052 | -0.6320 | No | ||
143 | DUSP16 | 2370082 2480450 | 15013 | -0.058 | -0.6372 | No | ||
144 | THRAP1 | 2470121 | 15024 | -0.059 | -0.6370 | No | ||
145 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 15032 | -0.059 | -0.6365 | No | ||
146 | RNF38 | 1940746 3140133 3840601 | 15210 | -0.072 | -0.6452 | No | ||
147 | RPS6KA5 | 2120563 7040546 | 15316 | -0.082 | -0.6498 | No | ||
148 | CLASP1 | 6860279 | 15375 | -0.088 | -0.6518 | No | ||
149 | MBNL2 | 3450707 | 15577 | -0.109 | -0.6613 | No | ||
150 | SP4 | 3850176 | 15664 | -0.118 | -0.6644 | No | ||
151 | AFF3 | 3870102 | 15740 | -0.128 | -0.6668 | No | ||
152 | CRSP7 | 4230408 | 15778 | -0.132 | -0.6670 | No | ||
153 | E2F6 | 3120133 3850332 4070324 | 15876 | -0.145 | -0.6704 | No | ||
154 | PAIP1 | 3870576 | 15958 | -0.158 | -0.6727 | No | ||
155 | MAPK1 | 3190193 6200253 | 15968 | -0.160 | -0.6711 | No | ||
156 | MLLT10 | 1410288 3290142 | 15992 | -0.163 | -0.6701 | No | ||
157 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15995 | -0.163 | -0.6681 | No | ||
158 | CDC73 | 1580132 | 16036 | -0.169 | -0.6680 | No | ||
159 | NAB1 | 430739 1230114 3390736 6660056 | 16041 | -0.169 | -0.6660 | No | ||
160 | SFRS3 | 770315 4230593 | 16062 | -0.172 | -0.6648 | No | ||
161 | SIPA1L2 | 4850731 | 16100 | -0.177 | -0.6645 | No | ||
162 | XPO7 | 2630215 6760014 | 16158 | -0.189 | -0.6651 | No | ||
163 | EFTUD1 | 5360736 | 16281 | -0.212 | -0.6689 | No | ||
164 | FBXO33 | 1510504 | 16425 | -0.243 | -0.6734 | No | ||
165 | HIPK1 | 110193 | 16427 | -0.243 | -0.6702 | No | ||
166 | PIAS1 | 5340301 | 16608 | -0.296 | -0.6761 | Yes | ||
167 | HIC2 | 4010433 | 16665 | -0.310 | -0.6750 | Yes | ||
168 | HNRPA0 | 2680048 | 16695 | -0.317 | -0.6724 | Yes | ||
169 | DNAJC13 | 4730091 | 16715 | -0.326 | -0.6691 | Yes | ||
170 | MTPN | 3940167 | 16739 | -0.333 | -0.6660 | Yes | ||
171 | SSH2 | 360056 | 16766 | -0.338 | -0.6629 | Yes | ||
172 | ZFX | 5900400 | 16812 | -0.352 | -0.6607 | Yes | ||
173 | VGLL4 | 6860463 | 16818 | -0.355 | -0.6562 | Yes | ||
174 | UTX | 2900017 6770452 | 16831 | -0.357 | -0.6521 | Yes | ||
175 | NUDT4 | 6760689 | 16925 | -0.388 | -0.6520 | Yes | ||
176 | CREBBP | 5690035 7040050 | 17020 | -0.421 | -0.6516 | Yes | ||
177 | LRP12 | 2370112 | 17030 | -0.425 | -0.6464 | Yes | ||
178 | BAZ2A | 730184 | 17111 | -0.455 | -0.6447 | Yes | ||
179 | JARID1B | 4730494 | 17130 | -0.464 | -0.6395 | Yes | ||
180 | BRD7 | 2120068 6200746 | 17142 | -0.470 | -0.6339 | Yes | ||
181 | ITGB1 | 5080156 6270528 | 17164 | -0.478 | -0.6287 | Yes | ||
182 | ITSN2 | 780484 | 17287 | -0.525 | -0.6284 | Yes | ||
183 | THRAP2 | 4920600 | 17307 | -0.533 | -0.6224 | Yes | ||
184 | CTDSPL | 4670546 | 17333 | -0.549 | -0.6164 | Yes | ||
185 | RYBP | 60746 | 17335 | -0.550 | -0.6092 | Yes | ||
186 | FMNL2 | 4060438 | 17349 | -0.557 | -0.6025 | Yes | ||
187 | CLPX | 6220156 | 17369 | -0.565 | -0.5960 | Yes | ||
188 | DOCK9 | 5080037 | 17413 | -0.584 | -0.5906 | Yes | ||
189 | EIF4ENIF1 | 2060341 | 17456 | -0.612 | -0.5848 | Yes | ||
190 | GAB1 | 2970156 | 17477 | -0.622 | -0.5776 | Yes | ||
191 | ATP2A2 | 1090075 3990279 | 17491 | -0.626 | -0.5700 | Yes | ||
192 | AXIN1 | 3360358 6940451 | 17501 | -0.629 | -0.5622 | Yes | ||
193 | UBE2G1 | 2230546 5420528 7040463 | 17589 | -0.678 | -0.5579 | Yes | ||
194 | PHF12 | 870400 3130687 | 17693 | -0.738 | -0.5537 | Yes | ||
195 | SIN3A | 2190121 | 17705 | -0.745 | -0.5444 | Yes | ||
196 | GNB1 | 2120397 | 17747 | -0.774 | -0.5364 | Yes | ||
197 | SRPK2 | 6380341 | 17799 | -0.805 | -0.5285 | Yes | ||
198 | FOXO1A | 3120670 | 17863 | -0.861 | -0.5205 | Yes | ||
199 | ANKRD50 | 870543 | 17881 | -0.875 | -0.5098 | Yes | ||
200 | BCL7A | 4560095 | 17886 | -0.878 | -0.4984 | Yes | ||
201 | PPP3CB | 6020156 | 17890 | -0.883 | -0.4868 | Yes | ||
202 | SPEN | 2060041 | 17938 | -0.930 | -0.4770 | Yes | ||
203 | TBK1 | 5690338 | 17955 | -0.941 | -0.4654 | Yes | ||
204 | RHOT1 | 6760692 | 17957 | -0.941 | -0.4530 | Yes | ||
205 | FBS1 | 2570520 | 18070 | -1.061 | -0.4450 | Yes | ||
206 | NCOA1 | 3610438 | 18091 | -1.092 | -0.4316 | Yes | ||
207 | HMGCS1 | 6620452 | 18107 | -1.120 | -0.4176 | Yes | ||
208 | UBE2Q1 | 610348 2350114 4210717 | 18134 | -1.169 | -0.4035 | Yes | ||
209 | AP3S1 | 5570044 | 18210 | -1.283 | -0.3905 | Yes | ||
210 | IRF2 | 5390044 | 18214 | -1.295 | -0.3735 | Yes | ||
211 | APLP2 | 3610037 | 18246 | -1.361 | -0.3571 | Yes | ||
212 | KBTBD2 | 2320014 | 18334 | -1.590 | -0.3408 | Yes | ||
213 | PDPK1 | 6650168 | 18388 | -1.747 | -0.3205 | Yes | ||
214 | PHF2 | 4060300 | 18458 | -1.970 | -0.2981 | Yes | ||
215 | KLF3 | 5130438 | 18530 | -2.428 | -0.2698 | Yes | ||
216 | MCL1 | 1660672 | 18541 | -2.493 | -0.2372 | Yes | ||
217 | LRIG1 | 1050136 | 18542 | -2.493 | -0.2042 | Yes | ||
218 | FGF13 | 630575 1570440 5360121 | 18545 | -2.512 | -0.1709 | Yes | ||
219 | TLE4 | 1450064 1500519 | 18569 | -2.751 | -0.1357 | Yes | ||
220 | PPP1R10 | 110136 3170725 3610484 | 18605 | -3.552 | -0.0905 | Yes | ||
221 | BTG1 | 4200735 6040131 6200133 | 18616 | -6.861 | 0.0000 | Yes |