Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D |
Enrichment Score (ES) | -0.6397886 |
Normalized Enrichment Score (NES) | -1.7363685 |
Nominal p-value | 0.0 |
FDR q-value | 0.006684202 |
FWER p-Value | 0.022 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RGMA | 2450711 | 74 | 2.932 | 0.0278 | No | ||
2 | SLC6A9 | 2470520 | 292 | 1.714 | 0.0346 | No | ||
3 | SDC1 | 3440471 6350408 | 321 | 1.645 | 0.0509 | No | ||
4 | MUTED | 3140452 4610086 4730348 | 364 | 1.567 | 0.0657 | No | ||
5 | LEFTY1 | 3290452 | 659 | 1.115 | 0.0618 | No | ||
6 | PPP3R1 | 1190041 1570487 | 810 | 0.980 | 0.0643 | No | ||
7 | RPS6KA1 | 4120647 | 830 | 0.963 | 0.0737 | No | ||
8 | CCND1 | 460524 770309 3120576 6980398 | 1030 | 0.830 | 0.0719 | No | ||
9 | TNFAIP1 | 6940593 | 1031 | 0.830 | 0.0809 | No | ||
10 | INHBB | 2680092 | 1107 | 0.775 | 0.0852 | No | ||
11 | APP | 2510053 | 1407 | 0.602 | 0.0755 | No | ||
12 | RBBP7 | 430113 450450 2370309 | 1647 | 0.507 | 0.0680 | No | ||
13 | MRPS25 | 610441 870128 1410368 | 1650 | 0.505 | 0.0734 | No | ||
14 | TARDBP | 870390 2350093 | 1746 | 0.472 | 0.0733 | No | ||
15 | RDBP | 6590044 | 1913 | 0.425 | 0.0689 | No | ||
16 | ARHGEF10 | 3120593 6900673 | 2295 | 0.318 | 0.0517 | No | ||
17 | SUV39H1 | 630112 | 2325 | 0.311 | 0.0535 | No | ||
18 | ZMYND11 | 630181 2570019 4850138 5360040 | 2730 | 0.209 | 0.0338 | No | ||
19 | DHX40 | 360672 | 2916 | 0.177 | 0.0256 | No | ||
20 | UBE2J1 | 4070133 | 2926 | 0.176 | 0.0271 | No | ||
21 | SS18L1 | 4610180 6550068 | 2988 | 0.167 | 0.0256 | No | ||
22 | TRPS1 | 870100 | 3008 | 0.165 | 0.0263 | No | ||
23 | AK2 | 4590458 4760195 6110097 | 3031 | 0.162 | 0.0269 | No | ||
24 | TRIM36 | 1400600 1980082 5130037 | 3032 | 0.162 | 0.0286 | No | ||
25 | PBX3 | 1300424 3710577 6180575 | 3041 | 0.161 | 0.0299 | No | ||
26 | RPS6KA3 | 1980707 | 3335 | 0.123 | 0.0154 | No | ||
27 | RHOC | 2060242 | 3508 | 0.108 | 0.0072 | No | ||
28 | ZFP36L2 | 510180 | 3517 | 0.107 | 0.0079 | No | ||
29 | EPAS1 | 5290156 | 3671 | 0.095 | 0.0006 | No | ||
30 | PFN2 | 730040 5700026 | 3882 | 0.082 | -0.0099 | No | ||
31 | DPYSL5 | 4900333 | 3899 | 0.081 | -0.0099 | No | ||
32 | MMP24 | 5340154 | 3900 | 0.081 | -0.0090 | No | ||
33 | PCDHA11 | 1510253 | 4156 | 0.069 | -0.0222 | No | ||
34 | ST8SIA2 | 2680082 | 4176 | 0.068 | -0.0225 | No | ||
35 | ATAD2 | 870242 2260687 | 4269 | 0.064 | -0.0268 | No | ||
36 | PAPOLA | 4200286 4850112 | 4378 | 0.059 | -0.0320 | No | ||
37 | YTHDF3 | 4540632 4670717 7040609 | 4429 | 0.057 | -0.0341 | No | ||
38 | ZBTB4 | 6450441 | 4449 | 0.057 | -0.0345 | No | ||
39 | PHF6 | 3120632 3990041 | 4473 | 0.056 | -0.0351 | No | ||
40 | CRIM1 | 130491 | 4636 | 0.051 | -0.0434 | No | ||
41 | MNT | 4920575 | 4693 | 0.049 | -0.0459 | No | ||
42 | NFIB | 460450 | 4827 | 0.045 | -0.0526 | No | ||
43 | MLLT6 | 3870168 | 4881 | 0.044 | -0.0550 | No | ||
44 | RAB22A | 110500 3830707 | 4900 | 0.044 | -0.0556 | No | ||
45 | NEUROD1 | 3060619 | 4920 | 0.043 | -0.0561 | No | ||
46 | EDNRB | 4280717 6400435 | 5001 | 0.041 | -0.0600 | No | ||
47 | PCDHA5 | 2970347 | 5050 | 0.040 | -0.0622 | No | ||
48 | FLT1 | 3830167 4920438 | 5147 | 0.038 | -0.0670 | No | ||
49 | OSBPL5 | 3840537 6040286 | 5248 | 0.036 | -0.0720 | No | ||
50 | ARID4B | 730754 6660026 | 5303 | 0.035 | -0.0746 | No | ||
51 | ASF1A | 7050020 | 5403 | 0.033 | -0.0796 | No | ||
52 | OLFM3 | 580112 1050072 4070204 | 5421 | 0.033 | -0.0802 | No | ||
53 | CXXC6 | 2810168 | 5509 | 0.031 | -0.0846 | No | ||
54 | RB1CC1 | 510494 7100072 | 5691 | 0.028 | -0.0941 | No | ||
55 | VLDLR | 870722 3060047 5340452 6550131 | 5740 | 0.027 | -0.0964 | No | ||
56 | MARCH8 | 60397 | 5871 | 0.025 | -0.1032 | No | ||
57 | ESR1 | 4060372 5860193 | 6008 | 0.023 | -0.1104 | No | ||
58 | NR4A2 | 60273 | 6029 | 0.023 | -0.1112 | No | ||
59 | RALGDS | 430463 | 6045 | 0.023 | -0.1118 | No | ||
60 | TUSC2 | 1580253 | 6091 | 0.022 | -0.1140 | No | ||
61 | ETV1 | 70735 2940603 5080463 | 6177 | 0.022 | -0.1183 | No | ||
62 | ZKSCAN1 | 6380605 | 6566 | 0.018 | -0.1392 | No | ||
63 | CREB5 | 2320368 | 6567 | 0.018 | -0.1390 | No | ||
64 | ZFPM2 | 460072 | 6800 | 0.016 | -0.1515 | No | ||
65 | NEO1 | 1990154 | 6875 | 0.016 | -0.1553 | No | ||
66 | PCDHA6 | 780333 2370280 | 6948 | 0.015 | -0.1591 | No | ||
67 | VSX1 | 4610605 6650112 | 7221 | 0.013 | -0.1737 | No | ||
68 | DAZAP2 | 6200102 | 7352 | 0.012 | -0.1807 | No | ||
69 | DCUN1D1 | 2360332 | 7372 | 0.012 | -0.1816 | No | ||
70 | TAOK2 | 110575 6380692 | 7653 | 0.011 | -0.1967 | No | ||
71 | EPHA2 | 5890056 | 7993 | 0.009 | -0.2150 | No | ||
72 | MYT1L | 5670369 6660403 | 8222 | 0.008 | -0.2273 | No | ||
73 | CYP26B1 | 2630142 | 8311 | 0.008 | -0.2320 | No | ||
74 | DRD1 | 430025 | 8411 | 0.008 | -0.2373 | No | ||
75 | PCDHA10 | 3830725 | 8522 | 0.007 | -0.2432 | No | ||
76 | TLOC1 | 4050309 | 8532 | 0.007 | -0.2436 | No | ||
77 | LHX8 | 5700347 | 8598 | 0.007 | -0.2471 | No | ||
78 | GNB5 | 4480736 6550722 6770463 | 8685 | 0.007 | -0.2517 | No | ||
79 | LHX6 | 2360731 3360397 | 8832 | 0.006 | -0.2595 | No | ||
80 | PAK7 | 3830164 | 8924 | 0.006 | -0.2644 | No | ||
81 | PRDM8 | 840746 | 8927 | 0.006 | -0.2645 | No | ||
82 | TIPARP | 50397 | 9033 | 0.005 | -0.2701 | No | ||
83 | PCDHA12 | 2810215 | 9117 | 0.005 | -0.2746 | No | ||
84 | ANK2 | 6510546 | 9151 | 0.005 | -0.2763 | No | ||
85 | ZBTB11 | 6520092 | 9411 | 0.004 | -0.2904 | No | ||
86 | YWHAZ | 1230717 | 9466 | 0.004 | -0.2933 | No | ||
87 | TRPV6 | 4010717 | 9577 | 0.004 | -0.2992 | No | ||
88 | PURA | 3870156 | 9895 | 0.003 | -0.3164 | No | ||
89 | ABCA1 | 6290156 | 10074 | 0.002 | -0.3260 | No | ||
90 | ADAM9 | 3360411 | 10076 | 0.002 | -0.3261 | No | ||
91 | NPAS3 | 630408 4610066 | 10146 | 0.002 | -0.3298 | No | ||
92 | KLF12 | 1660095 4810288 5340546 6520286 | 10298 | 0.002 | -0.3380 | No | ||
93 | PCDHA1 | 940026 540484 | 10314 | 0.002 | -0.3388 | No | ||
94 | MEF2C | 670025 780338 | 10376 | 0.002 | -0.3421 | No | ||
95 | NEUROD6 | 4670731 | 10794 | 0.000 | -0.3648 | No | ||
96 | ALX4 | 3870019 | 10815 | 0.000 | -0.3658 | No | ||
97 | BRP44L | 1340605 | 11040 | -0.000 | -0.3780 | No | ||
98 | NTN4 | 6940398 | 11075 | -0.000 | -0.3799 | No | ||
99 | HLF | 2370113 | 11089 | -0.000 | -0.3806 | No | ||
100 | KCNMA1 | 1450402 | 11150 | -0.001 | -0.3838 | No | ||
101 | RSBN1 | 7000487 | 11194 | -0.001 | -0.3861 | No | ||
102 | OSBPL8 | 50603 | 11296 | -0.001 | -0.3916 | No | ||
103 | PCDHA3 | 3840402 | 11387 | -0.001 | -0.3965 | No | ||
104 | LATS2 | 4480593 6020494 | 11526 | -0.002 | -0.4040 | No | ||
105 | SYNC1 | 580114 | 11577 | -0.002 | -0.4067 | No | ||
106 | SLC2A4 | 540441 | 11888 | -0.003 | -0.4235 | No | ||
107 | BAMBI | 6650463 | 11938 | -0.003 | -0.4261 | No | ||
108 | LUC7L2 | 1850402 6350088 | 12022 | -0.004 | -0.4306 | No | ||
109 | ECT2 | 3830086 | 12105 | -0.004 | -0.4350 | No | ||
110 | DDHD1 | 3450241 3940523 6380156 | 12425 | -0.005 | -0.4523 | No | ||
111 | ATP2B2 | 3780397 | 12439 | -0.005 | -0.4530 | No | ||
112 | CCNJ | 870047 | 12505 | -0.006 | -0.4564 | No | ||
113 | ARID4A | 520156 1050707 | 12546 | -0.006 | -0.4585 | No | ||
114 | PLXNA1 | 70066 | 12763 | -0.007 | -0.4702 | No | ||
115 | UBE2R2 | 1230504 | 12798 | -0.007 | -0.4720 | No | ||
116 | SSX2IP | 4610176 | 12904 | -0.008 | -0.4776 | No | ||
117 | SLITRK3 | 5910041 | 13015 | -0.008 | -0.4835 | No | ||
118 | PCDHA7 | 1850019 | 13271 | -0.010 | -0.4973 | No | ||
119 | KLHL18 | 4560075 | 13341 | -0.011 | -0.5009 | No | ||
120 | RAD23B | 2190671 | 13348 | -0.011 | -0.5011 | No | ||
121 | E2F5 | 5860575 | 13405 | -0.011 | -0.5040 | No | ||
122 | RAB11FIP1 | 2470333 | 13442 | -0.012 | -0.5058 | No | ||
123 | PRRX1 | 4120193 4480390 | 13546 | -0.013 | -0.5113 | No | ||
124 | ANKRD13C | 5270202 | 13588 | -0.013 | -0.5134 | No | ||
125 | RGL1 | 1500097 6900450 | 13709 | -0.015 | -0.5198 | No | ||
126 | PLAG1 | 1450142 3870139 6520039 | 13805 | -0.016 | -0.5248 | No | ||
127 | FOXL2 | 5670537 | 13884 | -0.017 | -0.5288 | No | ||
128 | FGD5 | 3520438 4060500 | 13957 | -0.018 | -0.5325 | No | ||
129 | LASS6 | 5890576 6520138 | 13982 | -0.019 | -0.5336 | No | ||
130 | PGBD5 | 1190047 | 14029 | -0.019 | -0.5359 | No | ||
131 | POLQ | 1050053 2190102 | 14042 | -0.020 | -0.5364 | No | ||
132 | RABEP1 | 4760427 6200463 | 14076 | -0.020 | -0.5379 | No | ||
133 | PARP8 | 4150204 | 14140 | -0.021 | -0.5411 | No | ||
134 | UBE2B | 4780497 | 14177 | -0.022 | -0.5429 | No | ||
135 | FNDC3A | 2690097 3290044 | 14220 | -0.023 | -0.5449 | No | ||
136 | DNAJA2 | 2630253 6860358 | 14317 | -0.026 | -0.5498 | No | ||
137 | NEK9 | 3440402 | 14327 | -0.026 | -0.5500 | No | ||
138 | CUGBP2 | 6180121 6840139 | 14416 | -0.028 | -0.5545 | No | ||
139 | NR4A3 | 2900021 5860095 5910039 | 14428 | -0.029 | -0.5548 | No | ||
140 | ARHGEF17 | 2060008 | 14436 | -0.029 | -0.5549 | No | ||
141 | MTUS1 | 780348 4920609 | 14442 | -0.030 | -0.5548 | No | ||
142 | MINK1 | 5860647 | 14661 | -0.039 | -0.5662 | No | ||
143 | WEE1 | 3390070 | 14710 | -0.041 | -0.5684 | No | ||
144 | NR2C2 | 6100097 | 14727 | -0.042 | -0.5688 | No | ||
145 | CFL2 | 380239 6200368 | 14738 | -0.043 | -0.5689 | No | ||
146 | ZNF385 | 450176 4810358 | 14910 | -0.053 | -0.5776 | No | ||
147 | YPEL2 | 5560609 | 15102 | -0.065 | -0.5873 | No | ||
148 | GABPB2 | 6130450 7050735 | 15159 | -0.068 | -0.5896 | No | ||
149 | SNF1LK | 6110403 | 15175 | -0.070 | -0.5897 | No | ||
150 | MTMR3 | 1050014 4920180 | 15258 | -0.076 | -0.5933 | No | ||
151 | RPS6KA5 | 2120563 7040546 | 15316 | -0.082 | -0.5955 | No | ||
152 | OXR1 | 2370039 3190706 | 15376 | -0.088 | -0.5978 | No | ||
153 | TAL1 | 7040239 | 15388 | -0.090 | -0.5974 | No | ||
154 | DMTF1 | 5910047 1570497 2480100 6620239 | 15527 | -0.103 | -0.6038 | No | ||
155 | RAB6A | 3840463 4780731 | 15543 | -0.105 | -0.6035 | No | ||
156 | PCAF | 2230161 2570369 6550451 | 15571 | -0.108 | -0.6037 | No | ||
157 | MBNL2 | 3450707 | 15577 | -0.109 | -0.6028 | No | ||
158 | COL23A1 | 2030358 | 15665 | -0.118 | -0.6063 | No | ||
159 | E2F7 | 4200056 | 15707 | -0.123 | -0.6072 | No | ||
160 | FRMD4A | 2190176 | 15754 | -0.129 | -0.6083 | No | ||
161 | SF4 | 3830341 | 15869 | -0.144 | -0.6129 | No | ||
162 | ATXN1 | 5550156 | 16088 | -0.176 | -0.6229 | No | ||
163 | CRK | 1230162 4780128 | 16249 | -0.206 | -0.6293 | No | ||
164 | PERQ1 | 1340164 | 16382 | -0.234 | -0.6340 | No | ||
165 | PLEKHA3 | 5080068 | 16442 | -0.247 | -0.6345 | No | ||
166 | PURB | 5360138 | 16491 | -0.262 | -0.6342 | No | ||
167 | AEBP2 | 2970603 | 16594 | -0.292 | -0.6366 | Yes | ||
168 | RAB11A | 5360079 | 16595 | -0.292 | -0.6335 | Yes | ||
169 | HIC2 | 4010433 | 16665 | -0.310 | -0.6338 | Yes | ||
170 | BCL11A | 6860369 | 16672 | -0.312 | -0.6308 | Yes | ||
171 | ASF1B | 6590706 | 16768 | -0.339 | -0.6323 | Yes | ||
172 | LEF1 | 2470082 7100288 | 16790 | -0.347 | -0.6296 | Yes | ||
173 | ORMDL3 | 1340711 | 16830 | -0.357 | -0.6279 | Yes | ||
174 | MKNK2 | 1240020 5270092 | 16883 | -0.373 | -0.6267 | Yes | ||
175 | SENP1 | 6100537 | 16914 | -0.383 | -0.6241 | Yes | ||
176 | MKRN1 | 1410097 | 16957 | -0.400 | -0.6221 | Yes | ||
177 | MAP3K11 | 7000039 | 17016 | -0.419 | -0.6207 | Yes | ||
178 | BCL2L11 | 780044 4200601 | 17038 | -0.427 | -0.6172 | Yes | ||
179 | WDR37 | 2630519 6840347 | 17051 | -0.431 | -0.6132 | Yes | ||
180 | IQWD1 | 160475 | 17077 | -0.440 | -0.6098 | Yes | ||
181 | CDCA7 | 3060097 | 17252 | -0.511 | -0.6137 | Yes | ||
182 | SAR1B | 2510273 | 17274 | -0.520 | -0.6092 | Yes | ||
183 | MECP2 | 1940450 | 17281 | -0.523 | -0.6038 | Yes | ||
184 | HN1 | 3360156 | 17285 | -0.524 | -0.5983 | Yes | ||
185 | SMAD2 | 4200592 | 17397 | -0.576 | -0.5981 | Yes | ||
186 | KPNA2 | 3450114 | 17408 | -0.582 | -0.5923 | Yes | ||
187 | RBL1 | 3130372 | 17417 | -0.585 | -0.5864 | Yes | ||
188 | FEM1C | 60300 6130717 6980164 | 17520 | -0.641 | -0.5850 | Yes | ||
189 | ULK1 | 6100315 | 17557 | -0.663 | -0.5797 | Yes | ||
190 | NFYA | 5860368 | 17576 | -0.672 | -0.5734 | Yes | ||
191 | DUSP2 | 2370184 | 17590 | -0.679 | -0.5668 | Yes | ||
192 | TMEM16F | 5860008 | 17716 | -0.750 | -0.5654 | Yes | ||
193 | RRAGD | 670075 | 17728 | -0.755 | -0.5578 | Yes | ||
194 | ZDHHC9 | 3940204 | 17750 | -0.775 | -0.5506 | Yes | ||
195 | BRMS1L | 6110609 | 17778 | -0.791 | -0.5434 | Yes | ||
196 | IHPK1 | 1340053 | 17788 | -0.797 | -0.5353 | Yes | ||
197 | WDR45 | 1660538 | 17819 | -0.826 | -0.5280 | Yes | ||
198 | RABGAP1 | 5050397 | 17831 | -0.831 | -0.5195 | Yes | ||
199 | FOXJ2 | 2450441 | 17845 | -0.847 | -0.5111 | Yes | ||
200 | MAP3K14 | 5890435 | 17867 | -0.866 | -0.5028 | Yes | ||
201 | CREBL1 | 1340546 | 17878 | -0.872 | -0.4939 | Yes | ||
202 | RNF6 | 2640035 | 17989 | -0.968 | -0.4893 | Yes | ||
203 | TOB2 | 1240465 | 18153 | -1.195 | -0.4852 | Yes | ||
204 | ZFYVE26 | 6860152 | 18182 | -1.223 | -0.4735 | Yes | ||
205 | IRF2 | 5390044 | 18214 | -1.295 | -0.4611 | Yes | ||
206 | SPOP | 450035 | 18217 | -1.298 | -0.4471 | Yes | ||
207 | RUNX1 | 3840711 | 18253 | -1.370 | -0.4342 | Yes | ||
208 | PLEKHM1 | 1050161 1990750 | 18321 | -1.547 | -0.4210 | Yes | ||
209 | PPP6C | 2450670 | 18348 | -1.635 | -0.4047 | Yes | ||
210 | PLAGL2 | 1770148 | 18365 | -1.695 | -0.3872 | Yes | ||
211 | TOX | 3440053 | 18396 | -1.762 | -0.3697 | Yes | ||
212 | KLF13 | 4670563 | 18402 | -1.779 | -0.3506 | Yes | ||
213 | MAPK9 | 2060273 3780209 4070397 | 18410 | -1.795 | -0.3315 | Yes | ||
214 | MAML1 | 2760008 | 18415 | -1.816 | -0.3120 | Yes | ||
215 | ARHGEF18 | 2120279 | 18441 | -1.887 | -0.2929 | Yes | ||
216 | PHF2 | 4060300 | 18458 | -1.970 | -0.2724 | Yes | ||
217 | RASSF2 | 2480079 5720546 | 18511 | -2.328 | -0.2500 | Yes | ||
218 | MCL1 | 1660672 | 18541 | -2.493 | -0.2245 | Yes | ||
219 | CCND2 | 5340167 | 18568 | -2.711 | -0.1965 | Yes | ||
220 | TLE4 | 1450064 1500519 | 18569 | -2.751 | -0.1666 | Yes | ||
221 | BCL6 | 940100 | 18610 | -4.108 | -0.1242 | Yes | ||
222 | HRBL | 1850102 3830253 4780176 | 18611 | -4.602 | -0.0743 | Yes | ||
223 | BTG1 | 4200735 6040131 6200133 | 18616 | -6.861 | -0.0000 | Yes |