Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AAGCAAT,MIR-137 |
Enrichment Score (ES) | -0.6315733 |
Normalized Enrichment Score (NES) | -1.633913 |
Nominal p-value | 0.0 |
FDR q-value | 0.024661735 |
FWER p-Value | 0.186 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | UBE2H | 1980142 2970079 | 277 | 1.757 | 0.0296 | No | ||
2 | MAPKAPK2 | 2850500 | 572 | 1.240 | 0.0452 | No | ||
3 | HNRPDL | 1050102 1090181 5360471 | 789 | 0.998 | 0.0588 | No | ||
4 | CDC42 | 1240168 3440278 4480519 5290162 | 1574 | 0.535 | 0.0299 | No | ||
5 | TARDBP | 870390 2350093 | 1746 | 0.472 | 0.0327 | No | ||
6 | DDX3X | 2190020 | 2105 | 0.368 | 0.0226 | No | ||
7 | ABHD6 | 630717 | 2327 | 0.310 | 0.0185 | No | ||
8 | PPP5C | 3130047 | 2616 | 0.236 | 0.0089 | No | ||
9 | ST3GAL3 | 2810601 | 2680 | 0.222 | 0.0111 | No | ||
10 | ZMYND11 | 630181 2570019 4850138 5360040 | 2730 | 0.209 | 0.0138 | No | ||
11 | SON | 3120148 5860239 7040403 | 2868 | 0.186 | 0.0111 | No | ||
12 | EIF4A2 | 1170494 1740711 2850504 | 3315 | 0.126 | -0.0099 | No | ||
13 | SH3BP5 | 7100408 | 3867 | 0.083 | -0.0376 | No | ||
14 | LBX1 | 1300164 4060204 | 3958 | 0.078 | -0.0405 | No | ||
15 | CRSP2 | 1940059 | 3974 | 0.078 | -0.0393 | No | ||
16 | ASPH | 360722 1940039 2100066 2340121 2650113 2810064 2970008 3140040 3800750 4210014 4280133 4590035 4760433 6370671 6940338 | 4077 | 0.073 | -0.0430 | No | ||
17 | SGCD | 2940685 5080753 | 4169 | 0.068 | -0.0462 | No | ||
18 | KLHL10 | 780139 | 4298 | 0.062 | -0.0516 | No | ||
19 | RNF128 | 1230300 5670273 | 4503 | 0.055 | -0.0612 | No | ||
20 | WIF1 | 7100184 | 4545 | 0.054 | -0.0621 | No | ||
21 | FLRT2 | 4200035 | 4553 | 0.054 | -0.0611 | No | ||
22 | PTGFRN | 4120524 | 4599 | 0.052 | -0.0622 | No | ||
23 | RPS13 | 1570364 | 4737 | 0.048 | -0.0684 | No | ||
24 | PDLIM3 | 1410095 | 4739 | 0.048 | -0.0672 | No | ||
25 | NEUROD1 | 3060619 | 4920 | 0.043 | -0.0759 | No | ||
26 | RUNX2 | 1400193 4230215 | 4938 | 0.042 | -0.0757 | No | ||
27 | MAB21L2 | 1770605 | 4984 | 0.042 | -0.0771 | No | ||
28 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 5220 | 0.037 | -0.0889 | No | ||
29 | ESRRA | 6550242 | 5257 | 0.036 | -0.0899 | No | ||
30 | BMPR2 | 5340066 6960328 | 5281 | 0.035 | -0.0903 | No | ||
31 | ARID4B | 730754 6660026 | 5303 | 0.035 | -0.0905 | No | ||
32 | FURIN | 4120168 | 5335 | 0.035 | -0.0913 | No | ||
33 | ZCCHC5 | 2650021 | 5348 | 0.034 | -0.0911 | No | ||
34 | RHOBTB1 | 1410010 | 5568 | 0.030 | -0.1022 | No | ||
35 | STC1 | 360161 | 5992 | 0.024 | -0.1245 | No | ||
36 | DEXI | 6220358 6550685 | 6348 | 0.020 | -0.1432 | No | ||
37 | NFASC | 1940619 2470156 4590168 6840524 | 6408 | 0.019 | -0.1459 | No | ||
38 | SLC17A6 | 4210576 | 6622 | 0.018 | -0.1570 | No | ||
39 | GRIN2A | 6550538 | 6663 | 0.017 | -0.1587 | No | ||
40 | MORC4 | 1740040 | 6700 | 0.017 | -0.1603 | No | ||
41 | TSSK3 | 1740673 | 6933 | 0.015 | -0.1724 | No | ||
42 | CHST9 | 4560092 | 7091 | 0.014 | -0.1806 | No | ||
43 | CACNA1G | 3060161 4810706 5550722 | 7167 | 0.013 | -0.1843 | No | ||
44 | RIMS4 | 6110500 | 7367 | 0.012 | -0.1948 | No | ||
45 | DUSP8 | 6650039 | 7771 | 0.010 | -0.2163 | No | ||
46 | ST18 | 5720537 | 7789 | 0.010 | -0.2170 | No | ||
47 | AMD1 | 6290128 | 7794 | 0.010 | -0.2170 | No | ||
48 | ESRRG | 4010181 | 7822 | 0.010 | -0.2182 | No | ||
49 | FBXL7 | 6620711 | 7883 | 0.010 | -0.2212 | No | ||
50 | GPR88 | 2450435 | 7918 | 0.010 | -0.2228 | No | ||
51 | MGAT5B | 380131 2570364 | 8321 | 0.008 | -0.2443 | No | ||
52 | NR3C2 | 2480324 6400093 | 8408 | 0.008 | -0.2488 | No | ||
53 | XPO4 | 3840551 | 8527 | 0.007 | -0.2550 | No | ||
54 | DCDC2 | 7000338 | 8755 | 0.006 | -0.2671 | No | ||
55 | DPYS | 3130670 | 8789 | 0.006 | -0.2687 | No | ||
56 | SHANK2 | 1500452 | 8809 | 0.006 | -0.2696 | No | ||
57 | RFX4 | 3710100 5340215 | 9226 | 0.005 | -0.2920 | No | ||
58 | PTPN2 | 130315 | 9321 | 0.005 | -0.2970 | No | ||
59 | CADPS | 2320181 | 9555 | 0.004 | -0.3095 | No | ||
60 | CBLN2 | 4760132 | 9794 | 0.003 | -0.3223 | No | ||
61 | PDCD6 | 4760239 | 9897 | 0.003 | -0.3278 | No | ||
62 | FLRT3 | 70685 2760497 6040519 | 9914 | 0.003 | -0.3286 | No | ||
63 | QKI | 5220093 6130044 | 9948 | 0.003 | -0.3303 | No | ||
64 | THBS4 | 3710348 | 9995 | 0.003 | -0.3327 | No | ||
65 | RCN1 | 2480041 | 10117 | 0.002 | -0.3392 | No | ||
66 | PLCB1 | 2570050 7100102 | 10158 | 0.002 | -0.3413 | No | ||
67 | KLF12 | 1660095 4810288 5340546 6520286 | 10298 | 0.002 | -0.3488 | No | ||
68 | MMP16 | 2680139 | 10370 | 0.002 | -0.3526 | No | ||
69 | DMRT2 | 2630068 | 10485 | 0.001 | -0.3587 | No | ||
70 | MUM1L1 | 4010411 | 10511 | 0.001 | -0.3601 | No | ||
71 | EPHA7 | 1190288 4010278 | 10549 | 0.001 | -0.3620 | No | ||
72 | PPARGC1A | 4670040 | 10674 | 0.001 | -0.3687 | No | ||
73 | SLC7A9 | 5420735 5700450 | 10802 | 0.000 | -0.3756 | No | ||
74 | BSN | 5270347 | 10803 | 0.000 | -0.3756 | No | ||
75 | HLF | 2370113 | 11089 | -0.000 | -0.3910 | No | ||
76 | RSBN1 | 7000487 | 11194 | -0.001 | -0.3966 | No | ||
77 | RIMS3 | 3890563 | 11414 | -0.001 | -0.4084 | No | ||
78 | DIO2 | 380504 540403 | 11478 | -0.002 | -0.4118 | No | ||
79 | SYNC1 | 580114 | 11577 | -0.002 | -0.4171 | No | ||
80 | RBMS3 | 6110722 | 11650 | -0.002 | -0.4209 | No | ||
81 | PRDM1 | 3170347 3520301 | 11775 | -0.003 | -0.4275 | No | ||
82 | GREM1 | 3940180 | 12073 | -0.004 | -0.4435 | No | ||
83 | STX16 | 70315 | 12083 | -0.004 | -0.4439 | No | ||
84 | ATOH8 | 4540204 | 12115 | -0.004 | -0.4455 | No | ||
85 | ACP1 | 1990435 | 12182 | -0.004 | -0.4490 | No | ||
86 | RORB | 6400035 | 12356 | -0.005 | -0.4582 | No | ||
87 | ERBB4 | 4610400 4810017 | 12582 | -0.006 | -0.4703 | No | ||
88 | SOX11 | 610279 | 12684 | -0.006 | -0.4756 | No | ||
89 | SYT1 | 840364 | 12700 | -0.006 | -0.4762 | No | ||
90 | SLC24A3 | 5080707 | 12936 | -0.008 | -0.4887 | No | ||
91 | ARHGEF7 | 1690441 | 13144 | -0.009 | -0.4997 | No | ||
92 | MITF | 380056 | 13233 | -0.010 | -0.5042 | No | ||
93 | RANBP2 | 4280338 | 13323 | -0.011 | -0.5088 | No | ||
94 | CUL4A | 1170088 2320008 2470278 | 13821 | -0.016 | -0.5353 | No | ||
95 | DR1 | 5860750 | 13864 | -0.016 | -0.5371 | No | ||
96 | KCNA2 | 5080403 | 14158 | -0.022 | -0.5525 | No | ||
97 | WNK4 | 1240682 | 14188 | -0.022 | -0.5535 | No | ||
98 | FNDC3A | 2690097 3290044 | 14220 | -0.023 | -0.5546 | No | ||
99 | PICALM | 1940280 | 14408 | -0.028 | -0.5640 | No | ||
100 | EPHA4 | 460750 | 14509 | -0.032 | -0.5686 | No | ||
101 | AKAP2 | 5550347 | 14757 | -0.044 | -0.5808 | No | ||
102 | PDE4A | 1190619 1340129 5720100 6370035 | 14878 | -0.051 | -0.5860 | No | ||
103 | RBM12 | 4570239 6040411 6660129 | 14903 | -0.052 | -0.5860 | No | ||
104 | ZNF385 | 450176 4810358 | 14910 | -0.053 | -0.5850 | No | ||
105 | MIB1 | 3800537 | 14980 | -0.056 | -0.5873 | No | ||
106 | PPARBP | 4280131 5690022 5860050 | 15015 | -0.058 | -0.5877 | No | ||
107 | THRAP1 | 2470121 | 15024 | -0.059 | -0.5866 | No | ||
108 | ZC3H6 | 130711 | 15052 | -0.061 | -0.5865 | No | ||
109 | TRIM33 | 580619 2230280 3990433 6200747 | 15075 | -0.063 | -0.5861 | No | ||
110 | SNF1LK | 6110403 | 15175 | -0.070 | -0.5897 | No | ||
111 | OXR1 | 2370039 3190706 | 15376 | -0.088 | -0.5983 | No | ||
112 | SGPL1 | 4480059 | 15442 | -0.094 | -0.5994 | No | ||
113 | RNF138 | 110142 3870129 6020441 6400193 | 15700 | -0.122 | -0.6103 | No | ||
114 | CUL3 | 1850520 | 15767 | -0.131 | -0.6105 | No | ||
115 | SNRK | 630021 2030731 6350017 | 15834 | -0.138 | -0.6106 | No | ||
116 | NAB2 | 1570014 | 16099 | -0.177 | -0.6204 | No | ||
117 | SLC25A5 | 1980672 | 16214 | -0.199 | -0.6215 | No | ||
118 | RAB21 | 5570070 | 16257 | -0.208 | -0.6185 | No | ||
119 | CHORDC1 | 6650577 | 16499 | -0.264 | -0.6249 | Yes | ||
120 | ZDHHC5 | 1690711 | 16543 | -0.276 | -0.6202 | Yes | ||
121 | AP1G1 | 2360671 | 16684 | -0.316 | -0.6198 | Yes | ||
122 | MTPN | 3940167 | 16739 | -0.333 | -0.6142 | Yes | ||
123 | SFRS5 | 3450176 6350008 | 16938 | -0.392 | -0.6150 | Yes | ||
124 | CREBBP | 5690035 7040050 | 17020 | -0.421 | -0.6087 | Yes | ||
125 | CTLA4 | 6590537 | 17187 | -0.486 | -0.6054 | Yes | ||
126 | INPP5A | 5910195 | 17298 | -0.530 | -0.5979 | Yes | ||
127 | CTDSPL | 4670546 | 17333 | -0.549 | -0.5858 | Yes | ||
128 | FMNL2 | 4060438 | 17349 | -0.557 | -0.5725 | Yes | ||
129 | CLPX | 6220156 | 17369 | -0.565 | -0.5592 | Yes | ||
130 | SLC6A6 | 6100300 | 17503 | -0.631 | -0.5503 | Yes | ||
131 | CCNG2 | 3190095 | 17629 | -0.698 | -0.5394 | Yes | ||
132 | RAP2C | 1690132 | 17697 | -0.741 | -0.5242 | Yes | ||
133 | OGT | 2360131 4610333 | 17729 | -0.756 | -0.5067 | Yes | ||
134 | BACH2 | 6760131 | 17749 | -0.775 | -0.4880 | Yes | ||
135 | PPP3CB | 6020156 | 17890 | -0.883 | -0.4732 | Yes | ||
136 | CSDA | 2470092 3060053 4780056 | 17909 | -0.906 | -0.4512 | Yes | ||
137 | RAB35 | 630056 | 17912 | -0.908 | -0.4282 | Yes | ||
138 | SPHK2 | 2030487 4120670 4850114 | 17916 | -0.910 | -0.4053 | Yes | ||
139 | DYRK1A | 3190181 | 18053 | -1.036 | -0.3864 | Yes | ||
140 | SRPK1 | 450110 | 18140 | -1.177 | -0.3612 | Yes | ||
141 | WSB1 | 870563 | 18195 | -1.252 | -0.3323 | Yes | ||
142 | DNAJB1 | 1090041 | 18244 | -1.357 | -0.3005 | Yes | ||
143 | EGR2 | 3800403 | 18270 | -1.404 | -0.2662 | Yes | ||
144 | PLAGL2 | 1770148 | 18365 | -1.695 | -0.2282 | Yes | ||
145 | ATP1B1 | 3130594 | 18366 | -1.702 | -0.1850 | Yes | ||
146 | SATB1 | 5670154 | 18523 | -2.380 | -0.1331 | Yes | ||
147 | CTDSP2 | 5340315 5690133 | 18565 | -2.686 | -0.0671 | Yes | ||
148 | TLE4 | 1450064 1500519 | 18569 | -2.751 | 0.0025 | Yes |