Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | LVAD_HEARTFAILURE_DN |
| Enrichment Score (ES) | 0.77519 |
| Normalized Enrichment Score (NES) | 1.5737007 |
| Nominal p-value | 0.005514706 |
| FDR q-value | 0.35242146 |
| FWER p-Value | 0.994 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GJA1 | 5220731 | 34 | 2.268 | 0.3346 | Yes | ||
| 2 | TGFBI | 2060446 6900112 | 113 | 1.357 | 0.5318 | Yes | ||
| 3 | S100A8 | 70112 | 218 | 0.875 | 0.6561 | Yes | ||
| 4 | G0S2 | 6550020 | 470 | 0.518 | 0.7194 | Yes | ||
| 5 | CD14 | 5570600 | 1119 | 0.257 | 0.7227 | Yes | ||
| 6 | CTSB | 1400524 2360064 | 1305 | 0.222 | 0.7456 | Yes | ||
| 7 | PLAU | 6510047 | 1348 | 0.214 | 0.7752 | Yes | ||
| 8 | IDH1 | 1990021 | 2731 | 0.074 | 0.7118 | No | ||
| 9 | CACNB2 | 1500095 7330707 | 3454 | 0.043 | 0.6794 | No | ||
| 10 | B3GALNT1 | 3390746 60131 | 4270 | 0.026 | 0.6394 | No | ||
| 11 | C6 | 1770154 2900129 | 4277 | 0.026 | 0.6430 | No | ||
| 12 | ZDHHC11 | 6620040 | 4355 | 0.025 | 0.6425 | No | ||
| 13 | CCL2 | 4760019 | 4626 | 0.022 | 0.6312 | No | ||
| 14 | JAM2 | 1410164 5080114 5290541 | 5464 | 0.014 | 0.5883 | No | ||
| 15 | F5 | 1990619 | 5536 | 0.014 | 0.5865 | No | ||
| 16 | CLCN3 | 510195 780176 1660093 3830372 | 8427 | 0.002 | 0.4313 | No | ||
| 17 | PTGER4 | 6400670 | 8909 | 0.001 | 0.4056 | No | ||
| 18 | TM4SF1 | 2570021 | 9306 | 0.000 | 0.3843 | No | ||
| 19 | GIMAP4 | 5570673 6550041 | 9636 | -0.001 | 0.3667 | No | ||
| 20 | IFIT1 | 5270373 | 9959 | -0.002 | 0.3496 | No | ||
| 21 | HEY2 | 3990504 | 10412 | -0.003 | 0.3257 | No | ||
| 22 | B3GALT2 | 430136 | 11398 | -0.006 | 0.2735 | No | ||
| 23 | AGTRL1 | 4280168 | 11621 | -0.007 | 0.2626 | No | ||
| 24 | PDE4B | 4480121 | 11731 | -0.007 | 0.2578 | No | ||
| 25 | PPP1R3C | 2640170 | 12745 | -0.012 | 0.2050 | No | ||
| 26 | CRYM | 3940528 | 13114 | -0.014 | 0.1873 | No | ||
| 27 | NKX2-5 | 5390438 | 13364 | -0.016 | 0.1762 | No | ||
| 28 | CXCL12 | 580546 4150750 4570068 | 14006 | -0.022 | 0.1450 | No | ||
| 29 | PDE4D | 2470528 6660014 | 14130 | -0.024 | 0.1420 | No | ||
| 30 | GPR22 | 1850035 | 14262 | -0.026 | 0.1387 | No | ||
| 31 | KCNJ8 | 870494 | 14277 | -0.026 | 0.1418 | No | ||
| 32 | TNFSF10 | 3170300 | 15969 | -0.077 | 0.0623 | No | ||
| 33 | MARCKS | 7040450 | 16339 | -0.100 | 0.0573 | No | ||
| 34 | PTGIS | 6620411 | 16396 | -0.105 | 0.0698 | No | ||
| 35 | PFKFB2 | 3940538 7100059 | 16410 | -0.106 | 0.0848 | No | ||
| 36 | RRAD | 4280129 | 17442 | -0.228 | 0.0632 | No |
