Details for gene set HSA04330_NOTCH_SIGNALING

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos
Phenotype	phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos
Upregulated in class	wtNotch
GeneSet	HSA04330_NOTCH_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.83170325
Normalized Enrichment Score (NES)	-1.7176057
Nominal p-value	0.0021929825
FDR q-value	0.09688626
FWER p-Value	0.453

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NCSTN	940601 6400594	289	0.734	0.0338	No
2	HDAC2	4050433	1050	0.273	0.0113	No
3	CREBBP	5690035 7040050	1349	0.214	0.0097	No
4	MAML1	2760008	1452	0.193	0.0172	No
5	HDAC1	2850670	1965	0.128	-0.0018	No
6	GCN5L2	2340609	2223	0.107	-0.0084	No
7	LFNG	5360711	2283	0.103	-0.0046	No
8	ADAM17	360292	2989	0.061	-0.0385	No
9	MFNG	1770242 4280348	3615	0.039	-0.0695	No
10	DTX4	4120433	3986	0.031	-0.0873	No
11	DLL1	1770377	4165	0.028	-0.0950	No
12	RBPJ	2360164 5550136 5720402	4423	0.024	-0.1072	No
13	CTBP2	430309 3710079	4996	0.018	-0.1368	No
14	NUMB	2450735 3800253 6350040	5338	0.015	-0.1542	No
15	SNW1	4010736	5339	0.015	-0.1532	No
16	JAG2	1500341	6990	0.007	-0.2415	No
17	JAG1	3440390	7728	0.004	-0.2809	No
18	RBPJL	5390019	8019	0.004	-0.2963	No
19	NUMBL	6130360 6200333	8200	0.003	-0.3058	No
20	CTBP1	3780315	8204	0.003	-0.3057	No
21	APH1A	4060273 4670465 6450711	8689	0.002	-0.3316	No
22	DLL3	4010093	8793	0.001	-0.3371	No
23	DLL4	6400403	10357	-0.003	-0.4211	No
24	DVL3	360156 5390075	12802	-0.012	-0.5518	No
25	DVL2	6110162	12968	-0.013	-0.5598	No
26	NOTCH2	2570397	13080	-0.014	-0.5649	No
27	NCOR2	1980575 6550050	13627	-0.018	-0.5930	No
28	PSEN2	130382	14767	-0.035	-0.6520	No
29	PCAF	2230161 2570369 6550451	14792	-0.035	-0.6509	No
30	RFNG	6290086	15174	-0.045	-0.6684	No
31	NOTCH4	2450040 6370707	15203	-0.046	-0.6668	No
32	DTX3	1690458	18267	-0.549	-0.7948	Yes
33	PTCRA	6940142	18343	-0.636	-0.7560	Yes
34	DTX2	4210041 7000008	18412	-0.747	-0.7094	Yes
35	HES1	4810280	18482	-0.988	-0.6466	Yes
36	DVL1	5900450 6510162	18509	-1.188	-0.5681	Yes
37	NOTCH3	3060603	18554	-1.615	-0.4619	Yes
38	PSEN1	130403 2030647 6100603	18571	-1.789	-0.3423	Yes
39	NOTCH1	3390114	18588	-2.330	-0.1865	Yes
40	DTX1	5900372	18597	-2.793	0.0010	Yes