Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | -0.5007068 |
Normalized Enrichment Score (NES) | -1.279937 |
Nominal p-value | 0.038817007 |
FDR q-value | 0.92339414 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | POLR1D | 70082 450750 6040458 | 25 | 2.240 | 0.0659 | No | ||
2 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 139 | 1.334 | 0.0999 | No | ||
3 | MFNG | 1770242 4280348 | 472 | 0.786 | 0.1055 | No | ||
4 | RRAGC | 5910348 | 579 | 0.703 | 0.1208 | No | ||
5 | RUNX1 | 3840711 | 697 | 0.634 | 0.1335 | No | ||
6 | NEDD4L | 6380368 | 953 | 0.516 | 0.1352 | No | ||
7 | OSR1 | 1500025 | 1102 | 0.459 | 0.1410 | No | ||
8 | WNT6 | 4570364 | 1439 | 0.350 | 0.1332 | No | ||
9 | LNX2 | 3130025 | 1621 | 0.300 | 0.1324 | No | ||
10 | GRB2 | 6650398 | 1627 | 0.299 | 0.1411 | No | ||
11 | GRB7 | 2100471 | 1648 | 0.292 | 0.1488 | No | ||
12 | SLC23A2 | 6660722 | 1712 | 0.276 | 0.1537 | No | ||
13 | EGLN1 | 2480180 3120253 6110195 | 1804 | 0.256 | 0.1564 | No | ||
14 | NUP88 | 2510044 6760180 | 1994 | 0.211 | 0.1525 | No | ||
15 | PLAGL2 | 1770148 | 2022 | 0.206 | 0.1572 | No | ||
16 | CORO2B | 2340035 4850390 | 2074 | 0.196 | 0.1603 | No | ||
17 | TNFSF13 | 2650170 | 2140 | 0.184 | 0.1624 | No | ||
18 | KCNN3 | 6520600 6420138 | 2488 | 0.129 | 0.1474 | No | ||
19 | ADAM12 | 3390132 4070347 | 3005 | 0.080 | 0.1218 | No | ||
20 | RIN1 | 510593 | 3035 | 0.078 | 0.1226 | No | ||
21 | FUT8 | 1340068 2340056 | 3140 | 0.070 | 0.1191 | No | ||
22 | CAMK2A | 1740333 1940112 4150292 | 3239 | 0.064 | 0.1157 | No | ||
23 | SORT1 | 1850242 2320632 3870537 | 3253 | 0.064 | 0.1169 | No | ||
24 | TNFRSF21 | 6380100 | 3403 | 0.054 | 0.1104 | No | ||
25 | SCG2 | 5670438 130671 | 3646 | 0.042 | 0.0986 | No | ||
26 | NTRK3 | 4050687 4070167 4610026 6100484 | 3795 | 0.036 | 0.0916 | No | ||
27 | PIM2 | 840136 5720692 7100577 | 3822 | 0.034 | 0.0913 | No | ||
28 | DSCAM | 1780050 2450731 2810438 | 3994 | 0.029 | 0.0829 | No | ||
29 | HIF3A | 2630053 2680102 6450364 | 4010 | 0.028 | 0.0829 | No | ||
30 | ITGA6 | 3830129 | 4052 | 0.027 | 0.0815 | No | ||
31 | KCNK12 | 4070072 | 4309 | 0.021 | 0.0682 | No | ||
32 | USP2 | 1190292 1240253 4850035 | 4326 | 0.021 | 0.0680 | No | ||
33 | SSH2 | 360056 | 4364 | 0.020 | 0.0666 | No | ||
34 | CXCL14 | 840114 6450324 | 4476 | 0.018 | 0.0611 | No | ||
35 | PCDH15 | 7000438 | 4540 | 0.017 | 0.0582 | No | ||
36 | NFATC4 | 2470735 | 4601 | 0.016 | 0.0554 | No | ||
37 | HR | 2690095 6200300 | 4622 | 0.016 | 0.0548 | No | ||
38 | CANX | 4760402 | 4684 | 0.015 | 0.0519 | No | ||
39 | RAPGEF4 | 6100563 | 4717 | 0.015 | 0.0506 | No | ||
40 | WDR20 | 1240373 | 4756 | 0.014 | 0.0490 | No | ||
41 | FYN | 2100468 4760520 4850687 | 4821 | 0.014 | 0.0459 | No | ||
42 | SIM1 | 1770332 | 4917 | 0.012 | 0.0412 | No | ||
43 | SLC24A3 | 5080707 | 5037 | 0.011 | 0.0351 | No | ||
44 | RAB26 | 5910025 | 5099 | 0.011 | 0.0321 | No | ||
45 | SORCS2 | 6350520 | 5221 | 0.010 | 0.0258 | No | ||
46 | UNC13B | 130735 | 5434 | 0.009 | 0.0146 | No | ||
47 | PACSIN3 | 4540369 4540400 5360037 6940129 | 5459 | 0.008 | 0.0135 | No | ||
48 | GPR37 | 2320093 | 5660 | 0.007 | 0.0029 | No | ||
49 | KCNB1 | 3610035 | 5690 | 0.007 | 0.0016 | No | ||
50 | HSD11B2 | 5900053 | 5801 | 0.007 | -0.0042 | No | ||
51 | SLC12A5 | 1980692 | 6126 | 0.005 | -0.0216 | No | ||
52 | DLL1 | 1770377 | 6187 | 0.005 | -0.0247 | No | ||
53 | CHRND | 840403 2260670 | 6264 | 0.005 | -0.0287 | No | ||
54 | TRIM23 | 580168 6510672 | 6304 | 0.005 | -0.0307 | No | ||
55 | WTAP | 4010176 | 6560 | 0.004 | -0.0444 | No | ||
56 | GATA2 | 6590280 | 6661 | 0.004 | -0.0497 | No | ||
57 | AP1S2 | 780279 4280707 | 6750 | 0.003 | -0.0544 | No | ||
58 | NTRK2 | 6220463 | 6876 | 0.003 | -0.0611 | No | ||
59 | TGFB3 | 1070041 | 6932 | 0.003 | -0.0640 | No | ||
60 | NBL1 | 2480021 | 7096 | 0.002 | -0.0727 | No | ||
61 | CPA4 | 3610100 | 7261 | 0.002 | -0.0816 | No | ||
62 | ASB14 | 5860427 | 7400 | 0.001 | -0.0890 | No | ||
63 | NHLH1 | 6100452 | 7527 | 0.001 | -0.0958 | No | ||
64 | BMP6 | 2100128 | 7649 | 0.001 | -0.1024 | No | ||
65 | SOX17 | 5270551 | 7672 | 0.001 | -0.1035 | No | ||
66 | PPARA | 2060026 | 7863 | 0.000 | -0.1138 | No | ||
67 | CHRDL1 | 1580037 6380204 | 7867 | 0.000 | -0.1140 | No | ||
68 | LAMA5 | 2680722 | 7898 | 0.000 | -0.1156 | No | ||
69 | COL4A4 | 1050541 | 8275 | -0.001 | -0.1360 | No | ||
70 | TCF2 | 870338 5050632 | 8657 | -0.002 | -0.1566 | No | ||
71 | GPM6B | 6220458 | 8665 | -0.002 | -0.1569 | No | ||
72 | ANKRD2 | 6590427 | 8672 | -0.002 | -0.1572 | No | ||
73 | PTPRJ | 4010707 | 9060 | -0.003 | -0.1781 | No | ||
74 | KLHL13 | 6590731 | 9139 | -0.003 | -0.1822 | No | ||
75 | MTSS1 | 780435 2370114 | 9195 | -0.003 | -0.1851 | No | ||
76 | SFTPC | 3290133 | 9206 | -0.003 | -0.1856 | No | ||
77 | DLL3 | 4010093 | 9233 | -0.003 | -0.1869 | No | ||
78 | FOXI1 | 3710095 6620195 | 9240 | -0.003 | -0.1871 | No | ||
79 | GRIA1 | 1340152 3780750 4920440 | 9243 | -0.003 | -0.1871 | No | ||
80 | ARVCF | 2190537 | 9295 | -0.003 | -0.1898 | No | ||
81 | TEAD4 | 1850239 6380519 | 9396 | -0.004 | -0.1951 | No | ||
82 | TREX2 | 4920707 | 9484 | -0.004 | -0.1997 | No | ||
83 | ANK2 | 6510546 | 9498 | -0.004 | -0.2003 | No | ||
84 | GFAP | 2060092 | 9916 | -0.005 | -0.2227 | No | ||
85 | MYOZ3 | 1990138 | 10153 | -0.006 | -0.2354 | No | ||
86 | CPZ | 70193 | 10231 | -0.006 | -0.2393 | No | ||
87 | NR4A1 | 6290161 | 10252 | -0.006 | -0.2402 | No | ||
88 | ARHGEF12 | 3990195 | 10289 | -0.006 | -0.2420 | No | ||
89 | MT3 | 1450537 | 10331 | -0.007 | -0.2440 | No | ||
90 | RTN4RL2 | 6450609 | 10387 | -0.007 | -0.2468 | No | ||
91 | EIF2C1 | 6900551 | 10589 | -0.007 | -0.2575 | No | ||
92 | FGF11 | 840292 | 10597 | -0.007 | -0.2576 | No | ||
93 | NEGR1 | 1940731 5130170 | 10604 | -0.008 | -0.2577 | No | ||
94 | MYH14 | 4010017 | 10775 | -0.008 | -0.2667 | No | ||
95 | ZNF205 | 6900022 | 10884 | -0.008 | -0.2723 | No | ||
96 | SOST | 1170195 | 11164 | -0.009 | -0.2872 | No | ||
97 | ODC1 | 5670168 | 11181 | -0.010 | -0.2877 | No | ||
98 | GDPD2 | 7000040 | 11240 | -0.010 | -0.2906 | No | ||
99 | NPEPPS | 2630731 | 11282 | -0.010 | -0.2925 | No | ||
100 | DNAJB5 | 2900215 | 11348 | -0.010 | -0.2957 | No | ||
101 | DOC2A | 6020121 | 11354 | -0.010 | -0.2957 | No | ||
102 | CCNL2 | 6520167 | 11495 | -0.011 | -0.3029 | No | ||
103 | CHST9 | 4560092 | 11588 | -0.012 | -0.3076 | No | ||
104 | MTUS1 | 780348 4920609 | 11715 | -0.012 | -0.3140 | No | ||
105 | ALDH1A2 | 2320301 | 11992 | -0.014 | -0.3286 | No | ||
106 | IRX6 | 4590025 | 12046 | -0.014 | -0.3310 | No | ||
107 | ROBO3 | 6550408 | 12090 | -0.015 | -0.3329 | No | ||
108 | CALB1 | 460070 | 12308 | -0.016 | -0.3442 | No | ||
109 | CDH5 | 5340487 | 12312 | -0.016 | -0.3439 | No | ||
110 | CALN1 | 3610722 | 12313 | -0.016 | -0.3434 | No | ||
111 | FSCN2 | 1230039 | 12379 | -0.017 | -0.3464 | No | ||
112 | POU2F3 | 2030601 | 12543 | -0.018 | -0.3547 | No | ||
113 | RASSF2 | 2480079 5720546 | 12584 | -0.018 | -0.3563 | No | ||
114 | COL4A3 | 5910075 | 12595 | -0.019 | -0.3563 | No | ||
115 | NEURL | 5390538 | 12723 | -0.020 | -0.3626 | No | ||
116 | CFL1 | 2340735 | 12815 | -0.021 | -0.3669 | No | ||
117 | GGN | 1410528 4210082 5290170 | 12839 | -0.021 | -0.3675 | No | ||
118 | PRKAG2 | 2340100 | 13045 | -0.023 | -0.3779 | No | ||
119 | DNMT3A | 4050068 4810717 | 13067 | -0.024 | -0.3784 | No | ||
120 | BRUNOL4 | 4490452 5080451 | 13130 | -0.024 | -0.3810 | No | ||
121 | CYP26A1 | 380022 2690600 | 13209 | -0.025 | -0.3845 | No | ||
122 | MDGA1 | 1170139 | 13286 | -0.026 | -0.3878 | No | ||
123 | NOL4 | 5050446 5360519 | 13500 | -0.030 | -0.3984 | No | ||
124 | ITGB4 | 1740021 3840482 | 14014 | -0.039 | -0.4251 | No | ||
125 | CDH2 | 520435 2450451 2760025 6650477 | 14128 | -0.042 | -0.4299 | No | ||
126 | TNNC2 | 3840079 | 14146 | -0.043 | -0.4296 | No | ||
127 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14176 | -0.044 | -0.4298 | No | ||
128 | PHACTR3 | 3850435 5900445 | 14182 | -0.044 | -0.4288 | No | ||
129 | INVS | 4200632 6620528 | 14205 | -0.044 | -0.4287 | No | ||
130 | EYA3 | 1580195 6510632 | 14256 | -0.046 | -0.4300 | No | ||
131 | LRP5 | 2100397 3170484 | 14393 | -0.049 | -0.4359 | No | ||
132 | SYT4 | 5080193 | 14506 | -0.053 | -0.4404 | No | ||
133 | GJB2 | 5900609 6200487 | 14700 | -0.059 | -0.4491 | No | ||
134 | HMGN2 | 3140091 | 14721 | -0.060 | -0.4484 | No | ||
135 | ACTN3 | 3140541 6480598 | 14780 | -0.062 | -0.4497 | No | ||
136 | HOXB7 | 4540706 4610358 | 14814 | -0.063 | -0.4496 | No | ||
137 | SEMA3F | 5420601 6770731 | 14902 | -0.067 | -0.4523 | No | ||
138 | PLCB3 | 4670402 | 14955 | -0.069 | -0.4530 | No | ||
139 | IGSF8 | 1580592 | 14984 | -0.071 | -0.4524 | No | ||
140 | FGF8 | 6350504 | 14985 | -0.071 | -0.4503 | No | ||
141 | GPD1 | 2480095 | 15023 | -0.073 | -0.4501 | No | ||
142 | CAMK1D | 1660100 2350309 | 15194 | -0.082 | -0.4568 | No | ||
143 | IGFBP5 | 2360592 | 15461 | -0.100 | -0.4683 | No | ||
144 | TPM3 | 670600 3170296 5670167 6650471 | 15515 | -0.104 | -0.4680 | No | ||
145 | CORO2A | 3840605 6620390 | 15641 | -0.116 | -0.4713 | No | ||
146 | CENTG3 | 2470079 4610092 5050170 | 15695 | -0.122 | -0.4705 | No | ||
147 | POFUT1 | 1570458 | 15773 | -0.129 | -0.4708 | No | ||
148 | CNNM2 | 2650100 | 16080 | -0.169 | -0.4823 | No | ||
149 | ARHGAP24 | 540278 4540025 | 16219 | -0.186 | -0.4842 | No | ||
150 | CENTB1 | 2120093 | 16292 | -0.197 | -0.4822 | No | ||
151 | TNFAIP1 | 6940593 | 16414 | -0.216 | -0.4823 | No | ||
152 | LRP10 | 1580128 | 16444 | -0.220 | -0.4772 | No | ||
153 | SIPA1 | 5220687 | 16449 | -0.220 | -0.4708 | No | ||
154 | STC2 | 4920601 | 16621 | -0.244 | -0.4728 | No | ||
155 | SASH1 | 4070270 | 17029 | -0.314 | -0.4854 | No | ||
156 | CRELD1 | 2060253 | 17312 | -0.373 | -0.4895 | Yes | ||
157 | PSTPIP1 | 3190156 | 17411 | -0.399 | -0.4828 | Yes | ||
158 | ARID5A | 2450133 | 17414 | -0.400 | -0.4709 | Yes | ||
159 | PPP1R9B | 3130619 | 17416 | -0.400 | -0.4590 | Yes | ||
160 | SLC37A4 | 6400079 | 17529 | -0.435 | -0.4520 | Yes | ||
161 | SMAD3 | 6450671 | 17586 | -0.454 | -0.4414 | Yes | ||
162 | DEF6 | 840593 | 17636 | -0.469 | -0.4300 | Yes | ||
163 | ELOVL1 | 2450019 4760138 5340685 | 17672 | -0.481 | -0.4174 | Yes | ||
164 | PTK2B | 4730411 | 17741 | -0.505 | -0.4059 | Yes | ||
165 | SELL | 1190500 | 17889 | -0.579 | -0.3965 | Yes | ||
166 | GFRA1 | 3610152 | 17937 | -0.604 | -0.3810 | Yes | ||
167 | PPOX | 2640678 3850102 | 18005 | -0.646 | -0.3652 | Yes | ||
168 | HMGA1 | 6580408 | 18109 | -0.743 | -0.3485 | Yes | ||
169 | AIG1 | 2450091 | 18292 | -0.956 | -0.3296 | Yes | ||
170 | TTC17 | 2470440 | 18366 | -1.089 | -0.3009 | Yes | ||
171 | IGF2 | 6510020 | 18425 | -1.234 | -0.2670 | Yes | ||
172 | HEYL | 5860528 | 18454 | -1.339 | -0.2283 | Yes | ||
173 | GNAS | 630441 1850373 4050152 | 18457 | -1.366 | -0.1874 | Yes | ||
174 | ENO3 | 5270136 | 18458 | -1.372 | -0.1461 | Yes | ||
175 | RANGAP1 | 2320593 6650601 | 18470 | -1.439 | -0.1035 | Yes | ||
176 | CKM | 1450524 | 18529 | -1.841 | -0.0514 | Yes | ||
177 | HES6 | 540411 6550504 | 18532 | -1.866 | 0.0046 | Yes |