Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_Q6 |
Enrichment Score (ES) | -0.51010966 |
Normalized Enrichment Score (NES) | -1.3122764 |
Nominal p-value | 0.023131672 |
FDR q-value | 0.8290755 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TCF12 | 3610324 7000156 | 122 | 1.384 | 0.0300 | No | ||
2 | NR1D1 | 2360471 770746 6590204 | 253 | 1.024 | 0.0500 | No | ||
3 | PPP2CA | 3990113 | 414 | 0.833 | 0.0634 | No | ||
4 | ATP1B1 | 3130594 | 534 | 0.740 | 0.0765 | No | ||
5 | PDAP1 | 1410735 | 535 | 0.739 | 0.0960 | No | ||
6 | XPOT | 7050184 | 809 | 0.578 | 0.0965 | No | ||
7 | TRIM8 | 6130441 | 933 | 0.528 | 0.1038 | No | ||
8 | PSMD7 | 2030619 6220594 | 956 | 0.515 | 0.1162 | No | ||
9 | ICK | 1580746 3140021 | 1121 | 0.454 | 0.1193 | No | ||
10 | PKN3 | 2260538 | 1264 | 0.403 | 0.1223 | No | ||
11 | CYFIP1 | 5690082 | 1370 | 0.370 | 0.1264 | No | ||
12 | WNT6 | 4570364 | 1439 | 0.350 | 0.1319 | No | ||
13 | NEFH | 630239 | 1516 | 0.332 | 0.1366 | No | ||
14 | RBBP7 | 430113 450450 2370309 | 1520 | 0.331 | 0.1452 | No | ||
15 | PSMD12 | 730044 | 1793 | 0.259 | 0.1373 | No | ||
16 | SLC16A6 | 1690156 | 2047 | 0.200 | 0.1288 | No | ||
17 | YWHAZ | 1230717 | 2082 | 0.195 | 0.1322 | No | ||
18 | CDKN1A | 4050088 6400706 | 2242 | 0.164 | 0.1279 | No | ||
19 | BTK | 3130044 | 2260 | 0.162 | 0.1312 | No | ||
20 | LAMC1 | 4730025 | 2323 | 0.153 | 0.1319 | No | ||
21 | ABI3 | 1740563 | 2366 | 0.146 | 0.1335 | No | ||
22 | TRAF3 | 5690647 | 2380 | 0.145 | 0.1366 | No | ||
23 | POLR3E | 380152 | 2470 | 0.131 | 0.1353 | No | ||
24 | CMAS | 2190129 | 2543 | 0.123 | 0.1346 | No | ||
25 | GTF2B | 6860685 | 2553 | 0.122 | 0.1374 | No | ||
26 | APOBEC1 | 4610022 | 2578 | 0.121 | 0.1393 | No | ||
27 | GPX1 | 4150093 | 2593 | 0.119 | 0.1416 | No | ||
28 | RIN1 | 510593 | 3035 | 0.078 | 0.1198 | No | ||
29 | PSMD4 | 430068 | 3096 | 0.073 | 0.1185 | No | ||
30 | SCOC | 610048 2230053 | 3246 | 0.064 | 0.1121 | No | ||
31 | MCART1 | 5270059 | 3312 | 0.060 | 0.1101 | No | ||
32 | LRRFIP2 | 670575 730152 6590438 | 3411 | 0.054 | 0.1062 | No | ||
33 | COL27A1 | 1740390 | 3416 | 0.053 | 0.1074 | No | ||
34 | LTBP3 | 1190162 2650440 6520451 | 3420 | 0.053 | 0.1087 | No | ||
35 | VDR | 130156 510438 | 3447 | 0.052 | 0.1086 | No | ||
36 | PEA15 | 4590685 | 3455 | 0.052 | 0.1096 | No | ||
37 | ROCK2 | 1780035 5720025 | 3599 | 0.044 | 0.1030 | No | ||
38 | CASK | 2340215 3290576 6770215 | 3677 | 0.041 | 0.0999 | No | ||
39 | EIF4E | 1580403 70133 6380215 | 3698 | 0.039 | 0.0999 | No | ||
40 | APBA2BP | 5700341 | 3712 | 0.039 | 0.1002 | No | ||
41 | PITPNC1 | 3990017 | 3845 | 0.034 | 0.0939 | No | ||
42 | NEK6 | 3360687 | 3904 | 0.032 | 0.0916 | No | ||
43 | LAMA3 | 1190131 5290239 | 4040 | 0.027 | 0.0850 | No | ||
44 | DTNA | 1340600 1780731 2340278 2850132 | 4087 | 0.026 | 0.0832 | No | ||
45 | LAPTM5 | 5550372 | 4097 | 0.026 | 0.0834 | No | ||
46 | IDS | 360619 5720161 | 4206 | 0.023 | 0.0782 | No | ||
47 | IBRDC2 | 5130041 | 4221 | 0.023 | 0.0780 | No | ||
48 | PTP4A1 | 130692 | 4393 | 0.019 | 0.0693 | No | ||
49 | PCDH9 | 2100136 | 4424 | 0.019 | 0.0681 | No | ||
50 | NFATC4 | 2470735 | 4601 | 0.016 | 0.0590 | No | ||
51 | MARK1 | 450484 | 4606 | 0.016 | 0.0592 | No | ||
52 | KCNA2 | 5080403 | 4634 | 0.016 | 0.0582 | No | ||
53 | LAMC2 | 450692 2680041 4200059 4670148 | 4671 | 0.015 | 0.0566 | No | ||
54 | PFTK1 | 1780181 | 4880 | 0.013 | 0.0457 | No | ||
55 | SLC26A1 | 2190142 | 5061 | 0.011 | 0.0362 | No | ||
56 | DSCR1L1 | 940438 | 5199 | 0.010 | 0.0290 | No | ||
57 | GNAI1 | 4560390 | 5244 | 0.010 | 0.0269 | No | ||
58 | SPARC | 1690086 | 5368 | 0.009 | 0.0205 | No | ||
59 | SNCB | 3360133 | 5441 | 0.009 | 0.0168 | No | ||
60 | XLKD1 | 520441 | 5576 | 0.008 | 0.0097 | No | ||
61 | PTPRN | 5900577 | 5739 | 0.007 | 0.0011 | No | ||
62 | PLCD1 | 2030484 | 5837 | 0.007 | -0.0040 | No | ||
63 | HOXD3 | 6450154 | 6356 | 0.005 | -0.0319 | No | ||
64 | FAP | 4560019 | 6361 | 0.004 | -0.0320 | No | ||
65 | OMG | 6760066 | 6679 | 0.003 | -0.0492 | No | ||
66 | UCN2 | 4590372 | 6706 | 0.003 | -0.0505 | No | ||
67 | SLC35E4 | 2370711 | 6812 | 0.003 | -0.0561 | No | ||
68 | USP13 | 1450670 | 6824 | 0.003 | -0.0566 | No | ||
69 | IL9 | 3440338 | 7454 | 0.001 | -0.0907 | No | ||
70 | DSTN | 3140592 | 7475 | 0.001 | -0.0917 | No | ||
71 | EFNA1 | 3840672 | 7537 | 0.001 | -0.0950 | No | ||
72 | TRPV3 | 540341 | 7661 | 0.001 | -0.1017 | No | ||
73 | PHLDA2 | 4810494 | 8009 | -0.000 | -0.1205 | No | ||
74 | IL1RN | 2370333 | 8021 | -0.000 | -0.1211 | No | ||
75 | AP2B1 | 1450184 2370148 3520139 4850593 | 8111 | -0.000 | -0.1259 | No | ||
76 | SHC3 | 2690398 | 8135 | -0.000 | -0.1272 | No | ||
77 | CRYBA2 | 5900138 | 8164 | -0.000 | -0.1287 | No | ||
78 | HOXA11 | 6980133 | 8360 | -0.001 | -0.1392 | No | ||
79 | UCHL3 | 1240735 | 8690 | -0.002 | -0.1570 | No | ||
80 | SYT2 | 60609 | 8768 | -0.002 | -0.1611 | No | ||
81 | FBXW11 | 6450632 | 8833 | -0.002 | -0.1645 | No | ||
82 | S100A5 | 4120592 | 8855 | -0.002 | -0.1656 | No | ||
83 | ANXA7 | 6110446 | 9017 | -0.003 | -0.1743 | No | ||
84 | C3AR1 | 5720131 | 9055 | -0.003 | -0.1762 | No | ||
85 | SFTPC | 3290133 | 9206 | -0.003 | -0.1843 | No | ||
86 | MYBPH | 2190711 | 9262 | -0.003 | -0.1872 | No | ||
87 | PSMD11 | 2340538 6510053 | 9438 | -0.004 | -0.1966 | No | ||
88 | IGSF9 | 1770411 | 9440 | -0.004 | -0.1965 | No | ||
89 | P2RXL1 | 4730390 5220446 | 9468 | -0.004 | -0.1979 | No | ||
90 | PRDM1 | 3170347 3520301 | 9655 | -0.004 | -0.2079 | No | ||
91 | GJB3 | 2650040 | 9675 | -0.004 | -0.2088 | No | ||
92 | GAB2 | 1410280 2340520 4280040 | 9802 | -0.005 | -0.2155 | No | ||
93 | WDFY3 | 3610041 4560333 4570273 | 9856 | -0.005 | -0.2182 | No | ||
94 | LPP | 1660541 | 9876 | -0.005 | -0.2191 | No | ||
95 | GFAP | 2060092 | 9916 | -0.005 | -0.2211 | No | ||
96 | TIAL1 | 4150048 6510605 | 9938 | -0.005 | -0.2221 | No | ||
97 | SPATS2 | 2360066 | 10054 | -0.006 | -0.2282 | No | ||
98 | NR0B2 | 2470692 | 10243 | -0.006 | -0.2382 | No | ||
99 | KBTBD5 | 6350025 | 10281 | -0.006 | -0.2400 | No | ||
100 | ELK3 | 460377 1400762 3710497 | 10453 | -0.007 | -0.2491 | No | ||
101 | EIF3S1 | 6130368 6770044 | 10805 | -0.008 | -0.2680 | No | ||
102 | TRIB1 | 2320435 | 10950 | -0.009 | -0.2755 | No | ||
103 | SCEL | 3190129 | 10956 | -0.009 | -0.2756 | No | ||
104 | DHRS3 | 360609 | 11138 | -0.009 | -0.2852 | No | ||
105 | FGF12 | 1740446 2360037 | 11163 | -0.009 | -0.2862 | No | ||
106 | OLR1 | 50025 3840484 | 11452 | -0.011 | -0.3015 | No | ||
107 | AK5 | 6290348 | 11577 | -0.011 | -0.3080 | No | ||
108 | GPR3 | 2970452 | 11587 | -0.012 | -0.3082 | No | ||
109 | TLL1 | 2680315 | 11676 | -0.012 | -0.3126 | No | ||
110 | IL23A | 6290044 | 11722 | -0.012 | -0.3147 | No | ||
111 | PTPRH | 3870070 | 11730 | -0.012 | -0.3148 | No | ||
112 | SFN | 6290301 7510608 | 11843 | -0.013 | -0.3205 | No | ||
113 | RIMS1 | 5670022 | 11863 | -0.013 | -0.3212 | No | ||
114 | MMP7 | 1780497 | 11887 | -0.013 | -0.3221 | No | ||
115 | BMP2 | 6620687 | 12217 | -0.015 | -0.3395 | No | ||
116 | MAP1A | 4920576 | 12384 | -0.017 | -0.3481 | No | ||
117 | MMP9 | 580338 | 12449 | -0.017 | -0.3511 | No | ||
118 | ST18 | 5720537 | 12531 | -0.018 | -0.3550 | No | ||
119 | STX17 | 2260037 | 12563 | -0.018 | -0.3562 | No | ||
120 | PVALB | 5570450 | 12604 | -0.019 | -0.3579 | No | ||
121 | PSME4 | 380348 1770131 | 12615 | -0.019 | -0.3579 | No | ||
122 | EEF1A2 | 2260162 5290086 | 12708 | -0.020 | -0.3624 | No | ||
123 | GGN | 1410528 4210082 5290170 | 12839 | -0.021 | -0.3689 | No | ||
124 | COBL | 2480452 6110066 | 12881 | -0.022 | -0.3706 | No | ||
125 | DIRAS1 | 2640270 | 12952 | -0.022 | -0.3738 | No | ||
126 | FLNC | 2360048 5050270 | 13220 | -0.025 | -0.3876 | No | ||
127 | STAT5B | 6200026 | 13568 | -0.031 | -0.4056 | No | ||
128 | HSPB7 | 1190441 | 13656 | -0.033 | -0.4094 | No | ||
129 | NRIP3 | 1340372 | 13832 | -0.036 | -0.4180 | No | ||
130 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14176 | -0.044 | -0.4354 | No | ||
131 | RB1CC1 | 510494 7100072 | 14204 | -0.044 | -0.4357 | No | ||
132 | GADD45A | 2900717 | 14464 | -0.051 | -0.4484 | No | ||
133 | AXIN2 | 3850131 | 14475 | -0.052 | -0.4476 | No | ||
134 | PAPPA | 4230463 | 14537 | -0.054 | -0.4495 | No | ||
135 | ELA1 | 3390167 | 14564 | -0.055 | -0.4495 | No | ||
136 | CLSTN3 | 2350685 | 14694 | -0.059 | -0.4549 | No | ||
137 | EPHA2 | 5890056 | 14728 | -0.060 | -0.4551 | No | ||
138 | DCN | 510332 5340026 5900711 6550092 | 15093 | -0.077 | -0.4728 | No | ||
139 | MDFI | 6200041 | 15168 | -0.081 | -0.4747 | No | ||
140 | BLMH | 1410438 | 15217 | -0.084 | -0.4751 | No | ||
141 | ADORA2A | 1990687 | 15332 | -0.090 | -0.4789 | No | ||
142 | NFRKB | 3130538 | 15371 | -0.094 | -0.4785 | No | ||
143 | FHL3 | 1090369 2650017 | 15897 | -0.143 | -0.5032 | Yes | ||
144 | BAZ2A | 730184 | 15963 | -0.153 | -0.5027 | Yes | ||
145 | SCRN1 | 6040025 6580019 | 16039 | -0.164 | -0.5024 | Yes | ||
146 | PSMD2 | 4670706 5050364 | 16110 | -0.172 | -0.5016 | Yes | ||
147 | VIM | 20431 | 16155 | -0.179 | -0.4993 | Yes | ||
148 | HSPB8 | 540563 | 16239 | -0.190 | -0.4988 | Yes | ||
149 | VASP | 7050500 | 16324 | -0.202 | -0.4980 | Yes | ||
150 | TMEM24 | 5860039 | 16416 | -0.217 | -0.4972 | Yes | ||
151 | AP2A2 | 130082 | 16488 | -0.225 | -0.4951 | Yes | ||
152 | RIT1 | 5390338 | 16588 | -0.240 | -0.4941 | Yes | ||
153 | ABHD2 | 4850504 6840010 | 16884 | -0.287 | -0.5025 | Yes | ||
154 | ROM1 | 3130685 | 16945 | -0.299 | -0.4978 | Yes | ||
155 | UBE2C | 6130017 | 16960 | -0.302 | -0.4906 | Yes | ||
156 | TAGLN2 | 4560121 | 17048 | -0.318 | -0.4869 | Yes | ||
157 | ABHD4 | 6760450 | 17107 | -0.327 | -0.4814 | Yes | ||
158 | HDAC3 | 4060072 | 17146 | -0.336 | -0.4746 | Yes | ||
159 | RAB3D | 4210253 | 17193 | -0.348 | -0.4679 | Yes | ||
160 | PDGFRB | 6450279 | 17242 | -0.356 | -0.4611 | Yes | ||
161 | ADCK4 | 1660180 | 17298 | -0.370 | -0.4543 | Yes | ||
162 | LMNA | 520471 1500075 3190167 4210020 | 17323 | -0.375 | -0.4457 | Yes | ||
163 | CAPNS1 | 3940113 | 17458 | -0.413 | -0.4420 | Yes | ||
164 | DCTN2 | 540471 3780717 | 17597 | -0.457 | -0.4374 | Yes | ||
165 | TBC1D17 | 1780450 | 17679 | -0.484 | -0.4290 | Yes | ||
166 | ABCA2 | 5050039 | 17687 | -0.486 | -0.4165 | Yes | ||
167 | RTN4 | 50725 630647 870097 870184 | 17755 | -0.511 | -0.4066 | Yes | ||
168 | VAMP5 | 3830300 | 17762 | -0.515 | -0.3933 | Yes | ||
169 | AKT1S1 | 1660048 | 17795 | -0.530 | -0.3811 | Yes | ||
170 | ITPKC | 5420021 | 17825 | -0.549 | -0.3681 | Yes | ||
171 | CAMKK1 | 6370324 | 17826 | -0.549 | -0.3536 | Yes | ||
172 | SYTL1 | 510487 | 17890 | -0.579 | -0.3417 | Yes | ||
173 | PKP3 | 3710048 | 17995 | -0.636 | -0.3305 | Yes | ||
174 | ABCD1 | 5670373 | 17998 | -0.640 | -0.3137 | Yes | ||
175 | ALDOA | 6290672 | 18304 | -0.964 | -0.3048 | Yes | ||
176 | MAPK3 | 580161 4780035 | 18309 | -0.971 | -0.2793 | Yes | ||
177 | PADI4 | 1740075 4810441 | 18342 | -1.042 | -0.2535 | Yes | ||
178 | NDRG2 | 450403 | 18360 | -1.078 | -0.2259 | Yes | ||
179 | ECM1 | 940068 5390309 | 18422 | -1.229 | -0.1967 | Yes | ||
180 | ETV5 | 110017 | 18471 | -1.443 | -0.1611 | Yes | ||
181 | UBQLN1 | 110280 730376 2470133 6590594 | 18493 | -1.561 | -0.1210 | Yes | ||
182 | ENO1 | 5340128 | 18494 | -1.566 | -0.0796 | Yes | ||
183 | TGFBR2 | 1780711 1980537 6550398 | 18499 | -1.576 | -0.0381 | Yes | ||
184 | NCDN | 50040 1980739 3520603 | 18512 | -1.679 | 0.0056 | Yes |