Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | REACTOME_TCR_SIGNALING |
| Enrichment Score (ES) | -0.7887416 |
| Normalized Enrichment Score (NES) | -1.5558766 |
| Nominal p-value | 0.00477327 |
| FDR q-value | 0.22965379 |
| FWER p-Value | 0.857 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PTPRC | 130402 5290148 | 1547 | 0.456 | -0.0516 | No | ||
| 2 | NFKB1 | 5420358 | 2177 | 0.270 | -0.0667 | No | ||
| 3 | MAP3K7 | 6040068 | 2614 | 0.182 | -0.0776 | No | ||
| 4 | CHUK | 7050736 | 3349 | 0.094 | -0.1105 | No | ||
| 5 | ENAH | 1690292 5700300 | 5348 | 0.021 | -0.2166 | No | ||
| 6 | PLCG1 | 6020369 | 5664 | 0.017 | -0.2323 | No | ||
| 7 | GRAP2 | 7100441 1410647 | 6709 | 0.010 | -0.2878 | No | ||
| 8 | PIK3R1 | 4730671 | 7437 | 0.007 | -0.3264 | No | ||
| 9 | PIK3CB | 3800600 | 9320 | 0.001 | -0.4276 | No | ||
| 10 | PRKCQ | 2260170 3870193 | 10602 | -0.002 | -0.4964 | No | ||
| 11 | PAK1 | 4540315 | 11096 | -0.004 | -0.5226 | No | ||
| 12 | NCK1 | 6200575 6510050 | 12455 | -0.009 | -0.5950 | No | ||
| 13 | UBE2N | 520369 2900047 | 13944 | -0.022 | -0.6736 | No | ||
| 14 | FYB | 1690440 | 15164 | -0.062 | -0.7349 | No | ||
| 15 | RIPK2 | 5050072 6290632 | 15223 | -0.066 | -0.7334 | No | ||
| 16 | ZAP70 | 1410494 2260504 | 16061 | -0.152 | -0.7679 | Yes | ||
| 17 | LCP2 | 2680066 6650707 | 16085 | -0.156 | -0.7584 | Yes | ||
| 18 | IKBKB | 6840072 | 16263 | -0.180 | -0.7554 | Yes | ||
| 19 | LAT | 3170025 | 16883 | -0.315 | -0.7669 | Yes | ||
| 20 | CSK | 6350593 | 17026 | -0.354 | -0.7500 | Yes | ||
| 21 | PTEN | 3390064 | 17161 | -0.403 | -0.7293 | Yes | ||
| 22 | NFKBIA | 1570152 | 17293 | -0.450 | -0.7051 | Yes | ||
| 23 | RELA | 3830075 | 17328 | -0.467 | -0.6746 | Yes | ||
| 24 | WAS | 5270193 | 17487 | -0.535 | -0.6460 | Yes | ||
| 25 | LCK | 3360142 | 17548 | -0.561 | -0.6103 | Yes | ||
| 26 | BCL10 | 2360397 | 17788 | -0.705 | -0.5743 | Yes | ||
| 27 | CD4 | 1090010 | 18045 | -0.930 | -0.5236 | Yes | ||
| 28 | PDPK1 | 6650168 | 18263 | -1.250 | -0.4486 | Yes | ||
| 29 | CD3E | 3800056 | 18269 | -1.267 | -0.3611 | Yes | ||
| 30 | CD3D | 2810739 | 18272 | -1.277 | -0.2727 | Yes | ||
| 31 | ITK | 2230592 | 18426 | -1.732 | -0.1609 | Yes | ||
| 32 | CD3G | 2680288 | 18531 | -2.468 | 0.0046 | Yes |
