Details for gene set REACTOME_SIGNALING_BY

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	REACTOME_SIGNALING_BY_GPCR
Enrichment Score (ES)	-0.6794357
Normalized Enrichment Score (NES)	-1.6987509
Nominal p-value	0.0
FDR q-value	0.04051073
FWER p-Value	0.076

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	F2	5720280	145	2.239	0.0649	No
2	P2RY6	5290400	496	1.166	0.0838	No
3	LTB4R	1770056	1775	0.384	0.0271	No
4	GAL	3930279	2299	0.244	0.0067	No
5	CNR2	2760398	2442	0.216	0.0060	No
6	CCL25	450541 540435	2634	0.179	0.0015	No
7	P2RY10	6370039 6840204	2709	0.167	0.0029	No
8	PDYN	5720408	3170	0.110	-0.0184	No
9	AVP	2100113	3308	0.097	-0.0226	No
10	GNA12	1230301	3521	0.080	-0.0315	No
11	PTGER3	2900739 6770750	3635	0.073	-0.0352	No
12	ADCY6	450364 6290670 6940286	3840	0.061	-0.0443	No
13	GCGR	6620497	4116	0.049	-0.0576	No
14	HRH2	3840440	4141	0.048	-0.0573	No
15	GLP1R	6420528	4210	0.046	-0.0595	No
16	OPN1SW	6420377	4325	0.042	-0.0643	No
17	PDE4D	2470528 6660014	4558	0.035	-0.0758	No
18	EDNRA	6900133	4616	0.033	-0.0778	No
19	IL8RB	450592 1170537	4641	0.033	-0.0780	No
20	SCTR	2940070	5069	0.025	-0.1003	No
21	GLP2R	4150577 5290273 7050095	5123	0.024	-0.1024	No
22	P2RY2	2640180 2810128	5152	0.023	-0.1031	No
23	ADCYAP1R1	3390020 4280184 5360180	5186	0.023	-0.1042	No
24	GRK5	1940348 4670053	5251	0.022	-0.1069	No
25	ADM2	4060102	5269	0.022	-0.1072	No
26	MC2R	2970504	5321	0.021	-0.1092	No
27	GNAZ	6130296	5387	0.020	-0.1121	No
28	ADCYAP1	520086	5423	0.020	-0.1133	No
29	DRD1	430025	5550	0.019	-0.1196	No
30	CXCL11	1090551	5820	0.016	-0.1336	No
31	BAI3	940692	5943	0.015	-0.1397	No
32	PPYR1	1410072	6173	0.014	-0.1517	No
33	PLCB2	360132	6195	0.013	-0.1524	No
34	GPRC6A	4560576	6262	0.013	-0.1555	No
35	GPR17	5890671	6295	0.013	-0.1568	No
36	HCRTR2	2350463	6348	0.012	-0.1592	No
37	AVPR1A	2120300	6383	0.012	-0.1607	No
38	CASR	610504	6431	0.012	-0.1628	No
39	CALCA	5860167	6655	0.011	-0.1746	No
40	C5AR1	4540402	6673	0.011	-0.1751	No
41	PPY	2340373	6701	0.010	-0.1763	No
42	CCKBR	2760128	6731	0.010	-0.1775	No
43	KISS1	1580398	6774	0.010	-0.1795	No
44	GNAT1	5270048 6100170	6927	0.009	-0.1874	No
45	GNA14	3390017	7049	0.009	-0.1937	No
46	NTS	380300 2120592	7140	0.008	-0.1983	No
47	PTGDR	3850161	7247	0.008	-0.2037	No
48	GNGT1	5220156	7360	0.008	-0.2095	No
49	PIK3R1	4730671	7437	0.007	-0.2134	No
50	XCR1	5080072	7520	0.007	-0.2176	No
51	VIP	2850647	7543	0.007	-0.2186	No
52	CCR3	50427	7564	0.007	-0.2195	No
53	HCRTR1	1580273	7682	0.006	-0.2256	No
54	HTR6	4850022	7751	0.006	-0.2291	No
55	AKT1	5290746	7797	0.006	-0.2313	No
56	TACR2	1740358	7816	0.006	-0.2321	No
57	CCR10	4050097	8131	0.005	-0.2489	No
58	GALR1	6020452	8429	0.004	-0.2649	No
59	MTNR1A	380204	8518	0.004	-0.2695	No
60	CCK	6370368	8593	0.004	-0.2734	No
61	CHRM2	870750	8609	0.003	-0.2741	No
62	ADRA2A	5340520	8620	0.003	-0.2745	No
63	GIP	3170364	9028	0.002	-0.2965	No
64	CALCR	1690494	9114	0.002	-0.3010	No
65	DRD3	4780402	9191	0.002	-0.3051	No
66	AGTR1	4780524 2680592	9340	0.001	-0.3131	No
67	FSHR	610041 7040121	9604	0.001	-0.3273	No
68	PTGFR	3850373	9639	0.001	-0.3291	No
69	TSHR	1190687 5270364	9647	0.001	-0.3295	No
70	LHCGR	4560465 5860551	9733	0.000	-0.3341	No
71	P2RY4	630053	9752	0.000	-0.3350	No
72	IAPP	4230040	9964	-0.001	-0.3464	No
73	GRPR	6020170	10271	-0.001	-0.3630	No
74	TACR1	70358 3840411	10277	-0.001	-0.3632	No
75	TACR3	4780017	10344	-0.002	-0.3667	No
76	HCRT	2970463	10360	-0.002	-0.3675	No
77	ADRA1D	380035 540025	10479	-0.002	-0.3738	No
78	GHRHR	3130500 4010154	10543	-0.002	-0.3771	No
79	PTGER1	6100132	10594	-0.002	-0.3798	No
80	SST	6590142	10700	-0.003	-0.3854	No
81	CRHR2	4590672	10739	-0.003	-0.3873	No
82	FSHB	7100592	10775	-0.003	-0.3891	No
83	HRH1	840100	10822	-0.003	-0.3915	No
84	OXT	3850692	10823	-0.003	-0.3914	No
85	CRH	3710301	10901	-0.003	-0.3955	No
86	GCG	6220735	10903	-0.003	-0.3954	No
87	GRM6	2030398	10972	-0.003	-0.3990	No
88	KNG1	6400576 6770347	10994	-0.003	-0.4000	No
89	CX3CL1	3990707	11020	-0.004	-0.4013	No
90	ADORA1	6370520	11242	-0.004	-0.4131	No
91	CHRM5	5390333	11304	-0.005	-0.4163	No
92	EDN1	1770047	11775	-0.006	-0.4415	No
93	HTR1F	670148	11945	-0.007	-0.4504	No
94	IL8RA	1580100	11952	-0.007	-0.4505	No
95	DARC	3940050	12240	-0.008	-0.4658	No
96	AGT	7000575	12259	-0.008	-0.4665	No
97	CGA	630403	12643	-0.010	-0.4869	No
98	PIK3CA	6220129	12684	-0.010	-0.4887	No
99	CALCRL	4280035	12728	-0.011	-0.4907	No
100	AVPR2	360064	12746	-0.011	-0.4913	No
101	TSHB	6770500	12777	-0.011	-0.4925	No
102	SSTR1	2630471	12971	-0.012	-0.5026	No
103	CGB	580273	13301	-0.015	-0.5199	No
104	GHRH	4570575	13322	-0.015	-0.5205	No
105	LHB	1450368	13540	-0.017	-0.5317	No
106	TAC1	7000195 380706	13737	-0.019	-0.5417	No
107	GNAQ	430670 4210131 5900736	13759	-0.019	-0.5422	No
108	OPRM1	5360279	13775	-0.020	-0.5424	No
109	PNOC	1990114	13812	-0.020	-0.5437	No
110	BDKRB1	730592	13901	-0.021	-0.5477	No
111	CXCR6	3190440	13940	-0.022	-0.5491	No
112	P2RY1	6040121	13974	-0.022	-0.5502	No
113	NTSR1	6510136	13987	-0.023	-0.5501	No
114	MC5R	2640176	14299	-0.028	-0.5660	No
115	NPFF	2030280	14304	-0.028	-0.5653	No
116	VIPR2	6520050	14348	-0.029	-0.5667	No
117	GNA13	4590102	14479	-0.032	-0.5727	No
118	PTGER2	3170039	14609	-0.035	-0.5785	No
119	CCR6	5720368 6020176	14731	-0.039	-0.5838	No
120	SCT	2230348	14847	-0.044	-0.5886	No
121	HTR2A	360037 6330255	15018	-0.053	-0.5961	No
122	ADORA2A	1990687	15105	-0.058	-0.5988	No
123	ROCK1	130044	16034	-0.147	-0.6443	No
124	GNG2	2230390	16198	-0.171	-0.6475	No
125	P2RY14	6100497	16264	-0.180	-0.6452	No
126	PTGIR	2100563	16897	-0.319	-0.6691	Yes
127	RAMP1	2320168	17042	-0.359	-0.6652	Yes
128	GNB1	2120397	17111	-0.389	-0.6563	Yes
129	ADRBK1	1340333	17439	-0.512	-0.6573	Yes
130	GNAS	630441 1850373 4050152	17449	-0.517	-0.6410	Yes
131	NMB	3360735	17589	-0.586	-0.6295	Yes
132	PIK3CG	5890110	17834	-0.735	-0.6188	Yes
133	RHOG	6760575	17856	-0.752	-0.5955	Yes
134	ADRB2	3290373	18026	-0.899	-0.5755	Yes
135	F2R	4810180	18214	-1.148	-0.5483	Yes
136	PDPK1	6650168	18263	-1.250	-0.5103	Yes
137	CCL5	3710397	18504	-2.172	-0.4527	Yes
138	TBXA2R	2370292 3940066	18541	-2.536	-0.3723	Yes
139	XCL1	3800504	18565	-2.832	-0.2816	Yes
140	CCR7	2060687	18570	-2.914	-0.1872	Yes
141	RHOA	580142 5900131 5340450	18613	-5.837	0.0002	Yes