Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | REACTOME_GENE_EXPRESSION |
Enrichment Score (ES) | 0.67191744 |
Normalized Enrichment Score (NES) | 1.5949311 |
Nominal p-value | 0.0 |
FDR q-value | 0.04102526 |
FWER p-Value | 0.399 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RPL38 | 70040 4060138 6200601 | 2 | 7.446 | 0.1142 | Yes | ||
2 | SFRS2 | 50707 380593 | 63 | 3.079 | 0.1583 | Yes | ||
3 | RPL27A | 3130451 110195 6840494 | 72 | 2.999 | 0.2039 | Yes | ||
4 | EIF2S2 | 770095 2810487 | 214 | 1.852 | 0.2247 | Yes | ||
5 | RBM5 | 3520402 5270121 | 272 | 1.602 | 0.2462 | Yes | ||
6 | TXNL4A | 4120286 6510242 | 285 | 1.576 | 0.2698 | Yes | ||
7 | METTL3 | 360497 | 299 | 1.541 | 0.2927 | Yes | ||
8 | AARS | 1570279 2370136 | 302 | 1.539 | 0.3163 | Yes | ||
9 | U2AF2 | 450600 4670128 5420292 | 459 | 1.236 | 0.3268 | Yes | ||
10 | EIF4A1 | 1990341 2810300 | 469 | 1.223 | 0.3451 | Yes | ||
11 | ETF1 | 6770075 | 472 | 1.218 | 0.3637 | Yes | ||
12 | U2AF1 | 5130292 | 483 | 1.190 | 0.3814 | Yes | ||
13 | RARS | 380390 | 485 | 1.187 | 0.3996 | Yes | ||
14 | EIF2B2 | 4290048 | 490 | 1.174 | 0.4174 | Yes | ||
15 | SFRS6 | 60224 | 529 | 1.115 | 0.4325 | Yes | ||
16 | POLR2E | 2900348 3360348 | 562 | 1.082 | 0.4474 | Yes | ||
17 | CCAR1 | 3190092 | 682 | 0.940 | 0.4554 | Yes | ||
18 | EIF4B | 5390563 5270577 | 688 | 0.933 | 0.4694 | Yes | ||
19 | CCNH | 3190347 | 710 | 0.918 | 0.4824 | Yes | ||
20 | NARS | 1660722 | 729 | 0.900 | 0.4952 | Yes | ||
21 | RPS3A | 2470086 | 731 | 0.899 | 0.5090 | Yes | ||
22 | EIF5 | 6380750 | 736 | 0.893 | 0.5225 | Yes | ||
23 | RPS19 | 5860066 | 739 | 0.891 | 0.5361 | Yes | ||
24 | NUP93 | 2190273 | 782 | 0.852 | 0.5469 | Yes | ||
25 | TCEB1 | 1170619 | 792 | 0.846 | 0.5594 | Yes | ||
26 | GTF2H2 | 5130358 | 838 | 0.820 | 0.5695 | Yes | ||
27 | YBX1 | 1340039 4730500 | 866 | 0.802 | 0.5804 | Yes | ||
28 | NUP43 | 3360482 | 887 | 0.785 | 0.5914 | Yes | ||
29 | RPS24 | 5420377 | 892 | 0.783 | 0.6032 | Yes | ||
30 | GARS | 1230601 | 996 | 0.719 | 0.6086 | Yes | ||
31 | SF3A3 | 6660603 | 1233 | 0.589 | 0.6049 | Yes | ||
32 | CPSF1 | 6290064 | 1249 | 0.579 | 0.6130 | Yes | ||
33 | PHF5A | 2690519 | 1346 | 0.535 | 0.6160 | Yes | ||
34 | POLR2I | 4060400 | 1367 | 0.524 | 0.6230 | Yes | ||
35 | TBP | 1450601 2810193 | 1392 | 0.516 | 0.6296 | Yes | ||
36 | SNRPF | 3170280 | 1434 | 0.501 | 0.6351 | Yes | ||
37 | EIF2B1 | 4610082 7040242 | 1642 | 0.423 | 0.6303 | Yes | ||
38 | RAE1 | 7050121 | 1747 | 0.395 | 0.6308 | Yes | ||
39 | GTF2H1 | 2570746 2650148 | 1763 | 0.390 | 0.6359 | Yes | ||
40 | SFRS9 | 3800047 | 1809 | 0.371 | 0.6392 | Yes | ||
41 | SNRPD2 | 6110035 | 1814 | 0.369 | 0.6447 | Yes | ||
42 | NUP160 | 1990551 | 1868 | 0.355 | 0.6472 | Yes | ||
43 | CCNC | 3390750 | 1898 | 0.347 | 0.6510 | Yes | ||
44 | POLR2H | 5890242 | 1899 | 0.346 | 0.6563 | Yes | ||
45 | RPL14 | 5080471 | 2026 | 0.312 | 0.6543 | Yes | ||
46 | EIF4G1 | 4070446 | 2101 | 0.290 | 0.6547 | Yes | ||
47 | GTF2E2 | 4010441 | 2179 | 0.270 | 0.6547 | Yes | ||
48 | RPS23 | 7100594 | 2190 | 0.268 | 0.6583 | Yes | ||
49 | GTF2H3 | 50600 | 2294 | 0.245 | 0.6565 | Yes | ||
50 | SF3A2 | 3140500 | 2322 | 0.239 | 0.6587 | Yes | ||
51 | NUP62 | 1240128 | 2362 | 0.230 | 0.6601 | Yes | ||
52 | TAF12 | 3710746 4920300 6180603 | 2369 | 0.228 | 0.6633 | Yes | ||
53 | EEF1E1 | 4540711 | 2389 | 0.225 | 0.6657 | Yes | ||
54 | RPL5 | 840095 | 2401 | 0.222 | 0.6685 | Yes | ||
55 | RNMT | 1770500 | 2405 | 0.221 | 0.6717 | Yes | ||
56 | SFRS3 | 770315 4230593 | 2480 | 0.208 | 0.6709 | Yes | ||
57 | NUPL2 | 6550537 | 2519 | 0.199 | 0.6719 | Yes | ||
58 | CSTF1 | 4610129 | 2604 | 0.184 | 0.6702 | No | ||
59 | RPLP2 | 5290020 | 2669 | 0.174 | 0.6694 | No | ||
60 | MED6 | 6840500 | 2822 | 0.152 | 0.6635 | No | ||
61 | DNAJC8 | 4050075 | 2851 | 0.147 | 0.6642 | No | ||
62 | EEF1G | 3940603 | 2917 | 0.137 | 0.6628 | No | ||
63 | YARS | 70739 | 3021 | 0.126 | 0.6592 | No | ||
64 | TAF11 | 5720538 | 3066 | 0.122 | 0.6587 | No | ||
65 | RPS15A | 1170180 | 3079 | 0.120 | 0.6599 | No | ||
66 | RPS2 | 1340647 | 3130 | 0.114 | 0.6589 | No | ||
67 | RNGTT | 780152 780746 1090471 | 3136 | 0.114 | 0.6604 | No | ||
68 | SNRPG | 2340551 | 3164 | 0.111 | 0.6606 | No | ||
69 | SF3B4 | 110072 | 3180 | 0.110 | 0.6615 | No | ||
70 | FARS2 | 5340575 | 3236 | 0.103 | 0.6601 | No | ||
71 | RPL4 | 2940014 5420324 | 3429 | 0.087 | 0.6511 | No | ||
72 | MAGOH | 2370373 5050068 | 3453 | 0.085 | 0.6511 | No | ||
73 | RPL18A | 4570619 | 3479 | 0.083 | 0.6511 | No | ||
74 | NUDT21 | 1240167 | 3489 | 0.083 | 0.6518 | No | ||
75 | RDBP | 6590044 | 3535 | 0.079 | 0.6506 | No | ||
76 | SNRPB | 1230097 2940086 3520671 | 4027 | 0.053 | 0.6248 | No | ||
77 | RARS2 | 5570524 6290497 6900332 | 4046 | 0.052 | 0.6247 | No | ||
78 | RPL8 | 20296 | 4086 | 0.050 | 0.6233 | No | ||
79 | POLR2J | 7100372 | 4252 | 0.044 | 0.6151 | No | ||
80 | RPL27 | 1940088 | 4356 | 0.041 | 0.6101 | No | ||
81 | RPS21 | 3120673 | 4396 | 0.040 | 0.6086 | No | ||
82 | POLR2A | 5220647 | 4402 | 0.039 | 0.6090 | No | ||
83 | SNW1 | 4010736 | 4562 | 0.035 | 0.6009 | No | ||
84 | RPLP1 | 3140292 | 4652 | 0.032 | 0.5966 | No | ||
85 | PTBP1 | 4070736 | 4692 | 0.032 | 0.5949 | No | ||
86 | RPL6 | 6040735 | 4715 | 0.031 | 0.5942 | No | ||
87 | RPS13 | 1570364 | 4892 | 0.028 | 0.5851 | No | ||
88 | RANBP2 | 4280338 | 5005 | 0.026 | 0.5795 | No | ||
89 | EEF2 | 1050369 4670035 5890598 | 5042 | 0.025 | 0.5779 | No | ||
90 | TAF9 | 1850458 3830136 | 5092 | 0.024 | 0.5756 | No | ||
91 | EIF2S1 | 5360292 | 5509 | 0.019 | 0.5534 | No | ||
92 | RPS29 | 580324 | 5574 | 0.018 | 0.5502 | No | ||
93 | SFRS1 | 2360440 | 5619 | 0.018 | 0.5481 | No | ||
94 | EPRS | 3170301 | 6560 | 0.011 | 0.4974 | No | ||
95 | RNPS1 | 610736 1090021 | 7554 | 0.007 | 0.4437 | No | ||
96 | CDK7 | 2640451 | 7750 | 0.006 | 0.4333 | No | ||
97 | RPL17 | 2690167 5690504 | 8639 | 0.003 | 0.3852 | No | ||
98 | POLR2B | 3780138 | 8833 | 0.003 | 0.3748 | No | ||
99 | HARS | 6100487 | 9178 | 0.002 | 0.3562 | No | ||
100 | CCNT2 | 2100390 4150563 | 9605 | 0.001 | 0.3332 | No | ||
101 | TPR | 1990066 6550390 | 10129 | -0.001 | 0.3049 | No | ||
102 | GTF2A2 | 2230184 | 10188 | -0.001 | 0.3018 | No | ||
103 | NUP54 | 940546 2360156 4060278 | 11083 | -0.004 | 0.2534 | No | ||
104 | NUP153 | 7000452 | 11299 | -0.005 | 0.2418 | No | ||
105 | TAF4 | 1450170 | 11332 | -0.005 | 0.2402 | No | ||
106 | DHX9 | 60017 1170095 2260014 | 11353 | -0.005 | 0.2392 | No | ||
107 | EIF5B | 1190102 4200440 | 11389 | -0.005 | 0.2374 | No | ||
108 | SNRPB2 | 5720577 | 12382 | -0.009 | 0.1838 | No | ||
109 | POLR2C | 1690020 | 12853 | -0.011 | 0.1585 | No | ||
110 | NUP35 | 5340408 | 13229 | -0.014 | 0.1384 | No | ||
111 | SF3B1 | 7000632 | 13396 | -0.015 | 0.1297 | No | ||
112 | RPL18 | 6380181 3870195 | 13681 | -0.018 | 0.1146 | No | ||
113 | RPL41 | 6940112 | 13805 | -0.020 | 0.1082 | No | ||
114 | LARS2 | 7000706 | 14074 | -0.024 | 0.0941 | No | ||
115 | SNRPA1 | 1050735 6110131 | 14440 | -0.031 | 0.0748 | No | ||
116 | NFX1 | 450504 | 14588 | -0.035 | 0.0674 | No | ||
117 | RPS28 | 3830221 | 14895 | -0.046 | 0.0515 | No | ||
118 | RPL28 | 6900136 | 14904 | -0.047 | 0.0518 | No | ||
119 | SMC1A | 3060600 5700148 5890113 6370154 | 15141 | -0.061 | 0.0400 | No | ||
120 | RPS16 | 510722 | 15142 | -0.061 | 0.0409 | No | ||
121 | EIF4E | 1580403 70133 6380215 | 15251 | -0.069 | 0.0361 | No | ||
122 | TH1L | 1190632 | 15572 | -0.097 | 0.0203 | No | ||
123 | RPS5 | 580093 | 15580 | -0.099 | 0.0214 | No | ||
124 | IARS | 460528 1580739 1690008 | 15604 | -0.101 | 0.0217 | No | ||
125 | RPL37A | 7040717 | 15622 | -0.102 | 0.0224 | No | ||
126 | FAU | 7100465 | 15664 | -0.107 | 0.0218 | No | ||
127 | RPS20 | 1740092 | 15738 | -0.114 | 0.0196 | No | ||
128 | GTF2B | 6860685 | 15983 | -0.141 | 0.0085 | No | ||
129 | RPL11 | 3780435 | 16011 | -0.144 | 0.0093 | No | ||
130 | RPL19 | 5550592 | 16174 | -0.168 | 0.0031 | No | ||
131 | ERCC3 | 6900008 | 16176 | -0.168 | 0.0056 | No | ||
132 | SF3B3 | 3710044 | 16341 | -0.193 | -0.0003 | No | ||
133 | PRPF8 | 1230497 1570600 | 16395 | -0.203 | -0.0000 | No | ||
134 | SFRS5 | 3450176 6350008 | 16408 | -0.206 | 0.0025 | No | ||
135 | ELL | 3520731 | 16419 | -0.209 | 0.0052 | No | ||
136 | SF3B2 | 6590576 | 16469 | -0.218 | 0.0059 | No | ||
137 | TAF10 | 2760020 | 16743 | -0.279 | -0.0046 | No | ||
138 | SRRM1 | 6110025 | 16953 | -0.334 | -0.0108 | No | ||
139 | CCNT1 | 2450563 5390184 | 17431 | -0.508 | -0.0288 | No | ||
140 | CD2BP2 | 1580301 | 17570 | -0.573 | -0.0275 | No | ||
141 | PRPF4 | 430301 2970364 | 17698 | -0.656 | -0.0243 | No | ||
142 | WARS | 2570717 3290139 | 17753 | -0.685 | -0.0167 | No | ||
143 | SUPT4H1 | 6200056 | 17907 | -0.791 | -0.0128 | No | ||
144 | SFRS7 | 2760408 | 17927 | -0.808 | -0.0015 | No | ||
145 | EIF4EBP1 | 60132 5720148 | 18539 | -2.520 | 0.0042 | No |