DatasetSet_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls
#absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls
#absentNotch_versus_normalThy_repos
Phenotypephenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in classnormalThy
GeneSetREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
Enrichment Score (ES)-0.85972744
Normalized Enrichment Score (NES)-1.587245
Nominal p-value0.004140787
FDR q-value0.16499478
FWER p-Value0.67
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)		GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CD8087011223800.226-0.1077No
2CD863390471 620028046620.032-0.2275No
3PDCD1412008264580.012-0.3230No
4GRAP27100441 141064767090.010-0.3355No
5PTPN112230100 2470180 610052872570.008-0.3642No
6PIK3R1473067174370.007-0.3732No
7AKT1529074677970.006-0.3919No
8PAK1454031511096-0.004-0.5689No
9PIK3CA622012912684-0.010-0.6534No
10CTLA4659053714189-0.026-0.7319No
11ICOSLG7012814481-0.032-0.7447No
12FYN2100468 4760520 485068715761-0.116-0.8031No
13MAP3K8294028615842-0.125-0.7961No
14CSK635059317026-0.354-0.8279Yes
15LCK336014217548-0.561-0.8056Yes
16VAV1602048717855-0.751-0.7546Yes
17CD4109001018045-0.930-0.6814Yes
18PDPK1665016818263-1.250-0.5808Yes
19CD3E380005618269-1.267-0.4674Yes
20CD3D281073918272-1.277-0.3530Yes
21CD281400739 421009318406-1.672-0.2102Yes
22CD3G268028818531-2.4680.0046Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY: Random ES distribution   
Gene set null distribution of ES for REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY