Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | SIG_CHEMOTAXIS |
| Enrichment Score (ES) | -0.5968182 |
| Normalized Enrichment Score (NES) | -1.6565219 |
| Nominal p-value | 0.0074766357 |
| FDR q-value | 0.40394226 |
| FWER p-Value | 0.996 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 222 | 2.308 | 0.0687 | No | ||
| 2 | INPPL1 | 1460394_a_at | 1679 | 0.828 | 0.0305 | No | ||
| 3 | ACTR3 | 1426392_a_at 1434968_a_at 1452051_at | 2267 | 0.638 | 0.0254 | No | ||
| 4 | ITPR1 | 1417279_at 1443492_at 1457189_at 1460203_at | 3452 | 0.422 | -0.0142 | No | ||
| 5 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 4381 | 0.333 | -0.0452 | No | ||
| 6 | CFL1 | 1448346_at 1455138_x_at | 6120 | 0.223 | -0.1170 | No | ||
| 7 | ACTR2 | 1441660_at 1452587_at | 6804 | 0.190 | -0.1417 | No | ||
| 8 | RPS4X | 1416276_a_at | 7392 | 0.164 | -0.1629 | No | ||
| 9 | WASL | 1426776_at 1426777_a_at 1432155_at 1439832_at 1452193_a_at | 7644 | 0.153 | -0.1692 | No | ||
| 10 | GDI2 | 1420814_at 1420815_at 1421742_at 1431645_a_at 1435898_x_at 1436016_x_at 1456581_x_at 1457398_at | 7713 | 0.151 | -0.1671 | No | ||
| 11 | PAK2 | 1434250_at 1454887_at | 8173 | 0.134 | -0.1835 | No | ||
| 12 | SAG | 1419025_at | 8611 | 0.118 | -0.1995 | No | ||
| 13 | PAK3 | 1417923_at 1417924_at 1437318_at | 9173 | 0.098 | -0.2217 | No | ||
| 14 | ANGPTL2 | 1421002_at 1431848_at | 9354 | 0.092 | -0.2268 | No | ||
| 15 | AKT2 | 1421324_a_at 1424480_s_at 1455703_at | 11293 | 0.027 | -0.3144 | No | ||
| 16 | LIMK1 | 1417627_a_at 1425836_a_at 1456234_at 1458989_at | 11721 | 0.013 | -0.3335 | No | ||
| 17 | BTK | 1422755_at | 12029 | 0.002 | -0.3474 | No | ||
| 18 | PAK7 | 1440981_at 1446159_at 1455847_at 1458766_at | 12628 | -0.020 | -0.3741 | No | ||
| 19 | ARHGAP4 | 1419296_at 1443360_x_at 1458190_at | 13091 | -0.037 | -0.3939 | No | ||
| 20 | RHO | 1425171_at 1425172_at 1451617_at 1451618_at | 13690 | -0.060 | -0.4192 | No | ||
| 21 | PITX2 | 1424797_a_at 1450482_a_at | 14042 | -0.074 | -0.4327 | No | ||
| 22 | ARHGEF11 | 1443539_at 1446904_at 1457188_at | 14399 | -0.090 | -0.4459 | No | ||
| 23 | PDK1 | 1423747_a_at 1423748_at 1434974_at 1435836_at | 14436 | -0.091 | -0.4444 | No | ||
| 24 | ITPR3 | 1417297_at | 14448 | -0.092 | -0.4418 | No | ||
| 25 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 15215 | -0.127 | -0.4724 | No | ||
| 26 | PAK1 | 1420979_at 1420980_at 1450070_s_at 1459029_at | 15454 | -0.139 | -0.4785 | No | ||
| 27 | PIK3CD | 1422991_at 1422992_s_at 1443798_at 1453281_at 1458321_at | 15915 | -0.165 | -0.4939 | No | ||
| 28 | PAK6 | 1445475_at 1455200_at | 16562 | -0.206 | -0.5164 | No | ||
| 29 | WASF1 | 1418545_at 1440438_at | 17003 | -0.240 | -0.5283 | No | ||
| 30 | ROCK2 | 1423592_at 1451041_at | 17379 | -0.272 | -0.5361 | No | ||
| 31 | AKT3 | 1422078_at 1435260_at 1435879_at 1443222_at 1460307_at | 17784 | -0.314 | -0.5439 | No | ||
| 32 | ARHGAP1 | 1424307_at 1451309_at | 17914 | -0.328 | -0.5386 | No | ||
| 33 | ROCK1 | 1423444_at 1423445_at 1441162_at 1446518_at 1450994_at 1460729_at | 18236 | -0.372 | -0.5405 | No | ||
| 34 | MYLK | 1425504_at 1425505_at 1425506_at | 18845 | -0.476 | -0.5520 | No | ||
| 35 | PAK4 | 1428548_at | 19121 | -0.533 | -0.5464 | No | ||
| 36 | GDI1 | 1447613_at 1451070_at | 20226 | -0.848 | -0.5678 | Yes | ||
| 37 | CFL2 | 1418066_at 1418067_at 1431432_at | 20311 | -0.887 | -0.5414 | Yes | ||
| 38 | ITPR2 | 1421678_at 1424833_at 1424834_s_at 1427287_s_at 1427693_at 1444418_at 1444551_at 1447328_at | 20667 | -1.099 | -0.5201 | Yes | ||
| 39 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 21161 | -1.529 | -0.4904 | Yes | ||
| 40 | PIK3CG | 1422707_at 1422708_at | 21560 | -2.186 | -0.4338 | Yes | ||
| 41 | CDC42 | 1415724_a_at 1435807_at 1449574_a_at 1460708_s_at | 21769 | -2.901 | -0.3442 | Yes | ||
| 42 | PPP1R13B | 1434895_s_at 1442956_at 1459224_at | 21883 | -4.002 | -0.2127 | Yes | ||
| 43 | RACGAP1 | 1421546_a_at 1441889_x_at 1451358_a_at | 21926 | -6.293 | 0.0004 | Yes |
