| GS follow link to MSigDB | GS DETAILS | SIZE | ES | NES | NOM p-val | FDR q-val | FWER p-val | RANK AT MAX | LEADING EDGE | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCI_ARF6 DOWNSTREAM PATHWAY | Details ... | 27 | -0.77 | -1.96 | 0.000 | 0.012 | 0.012 | 2193 | tags=44%, list=10%, signal=49% |
| 2 | NCI_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF-ALPHA | Details ... | 34 | -0.70 | -1.88 | 0.002 | 0.038 | 0.076 | 2347 | tags=47%, list=11%, signal=53% |
| 3 | BIOCARTA_KERATINOCYTE DIFFERENTIATION | Details ... | 50 | -0.65 | -1.85 | 0.000 | 0.047 | 0.131 | 2533 | tags=36%, list=12%, signal=41% |
| 4 | NCI_ARF1 PATHWAY | Details ... | 14 | -0.82 | -1.80 | 0.000 | 0.088 | 0.297 | 1983 | tags=50%, list=9%, signal=55% |
| 5 | NETPATH_TCR | Details ... | 109 | -0.54 | -1.74 | 0.000 | 0.198 | 0.641 | 2535 | tags=39%, list=12%, signal=44% |
| 6 | NCI_CELLULAR ROLES OF ANTHRAX TOXIN | Details ... | 15 | -0.77 | -1.73 | 0.002 | 0.170 | 0.647 | 2193 | tags=40%, list=10%, signal=44% |
| 7 | NCI_JNK SIGNALING IN THE CD4+ TCR PATHWAY | Details ... | 32 | -0.65 | -1.73 | 0.004 | 0.163 | 0.686 | 1010 | tags=22%, list=5%, signal=23% |
| 8 | NCI_PAXILLIN-DEPENDENT EVENTS MEDIATED BY A4B1 | Details ... | 18 | -0.73 | -1.69 | 0.006 | 0.229 | 0.848 | 1517 | tags=39%, list=7%, signal=42% |
| 9 | NCI_RAS SIGNALING IN THE CD4+ TCR PATHWAY | Details ... | 33 | -0.63 | -1.68 | 0.010 | 0.252 | 0.895 | 558 | tags=18%, list=3%, signal=19% |
| 10 | NCI_CALCIUM SIGNALING IN THE CD4+ TCR PATHWAY | Details ... | 22 | -0.69 | -1.68 | 0.012 | 0.235 | 0.905 | 558 | tags=18%, list=3%, signal=19% |
| 11 | REACTOME_PLC_BETA_MEDIATED_EVENTS | Details ... | 10 | -0.81 | -1.67 | 0.004 | 0.217 | 0.908 | 3496 | tags=70%, list=16%, signal=83% |
| 12 | BIOCARTA_ROLE OF MAL IN RHO-MEDIATED ACTIVATION OF SRF | Details ... | 17 | -0.73 | -1.67 | 0.008 | 0.202 | 0.912 | 3700 | tags=47%, list=17%, signal=57% |
| 13 | REACTOME_G_PROTEIN_MEDIATED_EVENTS | Details ... | 12 | -0.79 | -1.67 | 0.012 | 0.188 | 0.914 | 3862 | tags=67%, list=18%, signal=81% |
| 14 | NETPATH_IL6 | Details ... | 60 | -0.56 | -1.66 | 0.007 | 0.193 | 0.935 | 2650 | tags=32%, list=12%, signal=36% |
| 15 | NCI_DOWNSTREAM SIGNALING IN NAÔVE CD8+ T CELLS | Details ... | 49 | -0.58 | -1.66 | 0.004 | 0.191 | 0.948 | 2535 | tags=31%, list=12%, signal=35% |
| 16 | NETPATH_IL3 | Details ... | 63 | -0.56 | -1.66 | 0.003 | 0.182 | 0.951 | 2650 | tags=35%, list=12%, signal=40% |
| 17 | BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION | Details ... | 16 | -0.72 | -1.64 | 0.014 | 0.204 | 0.972 | 3005 | tags=56%, list=14%, signal=65% |
| 18 | BIOCARTA_ROLE OF PI3K SUBUNIT P85 IN REGULATION OF ACTIN ORGANIZATION AND CELL MIGRATION | Details ... | 16 | -0.72 | -1.64 | 0.014 | 0.193 | 0.973 | 775 | tags=19%, list=4%, signal=19% |
| 19 | NCI_TCR SIGNALING IN NAÔVE CD4+ T CELLS | Details ... | 118 | -0.51 | -1.64 | 0.002 | 0.190 | 0.974 | 2535 | tags=31%, list=12%, signal=35% |
| 20 | BIOCARTA_MAPKINASE SIGNALING PATHWAY | Details ... | 53 | -0.56 | -1.63 | 0.009 | 0.205 | 0.982 | 2379 | tags=34%, list=11%, signal=38% |
| 21 | NETPATH_THROMBOPOIETIN | 40 | -0.58 | -1.62 | 0.013 | 0.227 | 0.994 | 2650 | tags=35%, list=12%, signal=40% | |
| 22 | BIOCARTA_MELANOCYTE DEVELOPMENT AND PIGMENTATION PATHWAY | 13 | -0.74 | -1.61 | 0.024 | 0.222 | 0.995 | 2193 | tags=38%, list=10%, signal=43% | |
| 23 | NETPATH_FLK2_FLT3 | 16 | -0.71 | -1.60 | 0.025 | 0.246 | 0.998 | 2650 | tags=50%, list=12%, signal=57% | |
| 24 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 13 | -0.73 | -1.60 | 0.031 | 0.239 | 0.998 | 3875 | tags=38%, list=18%, signal=47% | |
| 25 | BIOCARTA_CASPASE CASCADE IN APOPTOSIS | 21 | -0.66 | -1.59 | 0.017 | 0.257 | 1.000 | 2533 | tags=43%, list=12%, signal=48% | |
| 26 | BIOCARTA_HIV-1 NEF: NEGATIVE EFFECTOR OF FAS AND TNF | 51 | -0.54 | -1.58 | 0.016 | 0.276 | 1.000 | 2533 | tags=39%, list=12%, signal=44% | |
| 27 | NCI_TNF RECEPTOR SIGNALING PATHWAY | 247 | -0.45 | -1.58 | 0.000 | 0.267 | 1.000 | 2347 | tags=25%, list=11%, signal=28% | |
| 28 | NCI_CASPASE CASCADE IN APOPTOSIS | 45 | -0.57 | -1.57 | 0.015 | 0.260 | 1.000 | 2533 | tags=38%, list=12%, signal=43% | |
| 29 | BIOCARTA_T CELL RECEPTOR SIGNALING PATHWAY | 44 | -0.56 | -1.57 | 0.009 | 0.261 | 1.000 | 2535 | tags=39%, list=12%, signal=44% | |
| 30 | NETPATH_IL-7 | 15 | -0.68 | -1.56 | 0.032 | 0.272 | 1.000 | 1888 | tags=53%, list=9%, signal=58% | |
| 31 | BIOCARTA_HOW DOES SALMONELLA HIJACK A CELL | 11 | -0.75 | -1.56 | 0.033 | 0.274 | 1.000 | 167 | tags=18%, list=1%, signal=18% | |
| 32 | BIOCARTA_HUMAN CYTOMEGALOVIRUS AND MAP KINASE PATHWAYS | 16 | -0.67 | -1.56 | 0.038 | 0.266 | 1.000 | 2331 | tags=56%, list=11%, signal=63% | |
| 33 | NCI_TRAIL SIGNALING PATHWAY | 276 | -0.43 | -1.56 | 0.002 | 0.260 | 1.000 | 2389 | tags=25%, list=11%, signal=27% | |
| 34 | NETPATH_IL5 | 32 | -0.59 | -1.55 | 0.024 | 0.282 | 1.000 | 1888 | tags=31%, list=9%, signal=34% | |
| 35 | NETPATH_IL2 | 58 | -0.53 | -1.54 | 0.005 | 0.275 | 1.000 | 2331 | tags=34%, list=11%, signal=38% | |
| 36 | INOH_GENE EXPRESSION OF SOCS BY STAT DIMER | 13 | -0.72 | -1.54 | 0.029 | 0.293 | 1.000 | 2633 | tags=62%, list=12%, signal=70% | |
| 37 | BIOCARTA_EICOSANOID METABOLISM | 20 | -0.65 | -1.53 | 0.040 | 0.288 | 1.000 | 2440 | tags=35%, list=11%, signal=39% | |
| 38 | BIOCARTA_FMLP INDUCED CHEMOKINE GENE EXPRESSION IN HMC-1 CELLS | 29 | -0.60 | -1.53 | 0.028 | 0.282 | 1.000 | 2331 | tags=28%, list=11%, signal=31% | |
| 39 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | 45 | -0.54 | -1.53 | 0.020 | 0.277 | 1.000 | 482 | tags=20%, list=2%, signal=20% | |
| 40 | REACTOME_ACTIVATION_OF_APC_C_AND_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | 46 | -0.54 | -1.53 | 0.023 | 0.277 | 1.000 | 482 | tags=20%, list=2%, signal=20% | |
| 41 | NCI_A4B1 AND A4B7 INTEGRIN SIGNALING | 25 | -0.61 | -1.52 | 0.032 | 0.281 | 1.000 | 1517 | tags=28%, list=7%, signal=30% | |
| 42 | BIOCARTA_TNFR2 SIGNALING PATHWAY | 12 | -0.71 | -1.52 | 0.042 | 0.296 | 1.000 | 2331 | tags=50%, list=11%, signal=56% | |
| 43 | BIOCARTA_IGF-1 SIGNALING PATHWAY | 20 | -0.64 | -1.52 | 0.045 | 0.289 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 44 | BIOCARTA_TNF/STRESS RELATED SIGNALING | 23 | -0.62 | -1.51 | 0.028 | 0.288 | 1.000 | 1829 | tags=30%, list=8%, signal=33% | |
| 45 | NCI_ROLE OF CALCINEURIN-DEPENDENT NFAT SIGNALING IN LYMPHOCYTES | 80 | -0.48 | -1.51 | 0.021 | 0.297 | 1.000 | 2198 | tags=24%, list=10%, signal=26% | |
| 46 | NCI_PLASMA MEMBRANE ESTROGEN RECEPTOR SIGNALING | 278 | -0.42 | -1.50 | 0.000 | 0.299 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 47 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | 19 | -0.63 | -1.50 | 0.046 | 0.301 | 1.000 | 3043 | tags=37%, list=14%, signal=43% | |
| 48 | NCI_GLYPICAN PATHWAY | 419 | -0.41 | -1.50 | 0.000 | 0.302 | 1.000 | 2545 | tags=22%, list=12%, signal=25% | |
| 49 | BIOCARTA_INDUCTION OF APOPTOSIS THROUGH DR3 AND DR4/5 DEATH RECEPTORS | 19 | -0.65 | -1.50 | 0.056 | 0.299 | 1.000 | 2236 | tags=47%, list=10%, signal=53% | |
| 50 | NCI_REGULATION OF P38-ALPHA AND P38-BETA | 144 | -0.45 | -1.49 | 0.003 | 0.299 | 1.000 | 2198 | tags=23%, list=10%, signal=25% | |
| 51 | BIOCARTA_CALCIUM SIGNALING BY HBX OF HEPATITIS B VIRUS | 15 | -0.67 | -1.49 | 0.048 | 0.295 | 1.000 | 3043 | tags=40%, list=14%, signal=46% | |
| 52 | BIOCARTA_PDGF SIGNALING PATHWAY | 25 | -0.60 | -1.49 | 0.046 | 0.302 | 1.000 | 2193 | tags=36%, list=10%, signal=40% | |
| 53 | NCI_P38 MAPK SIGNALING PATHWAY | 164 | -0.44 | -1.48 | 0.000 | 0.304 | 1.000 | 2198 | tags=23%, list=10%, signal=25% | |
| 54 | CELLMAP_ANDROGENRECEPTOR | 74 | -0.49 | -1.48 | 0.025 | 0.306 | 1.000 | 2496 | tags=32%, list=11%, signal=36% | |
| 55 | REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS | 19 | -0.63 | -1.48 | 0.043 | 0.303 | 1.000 | 3043 | tags=37%, list=14%, signal=43% | |
| 56 | BIOCARTA_CERAMIDE SIGNALING PATHWAY | 49 | -0.52 | -1.48 | 0.025 | 0.305 | 1.000 | 2331 | tags=31%, list=11%, signal=34% | |
| 57 | BIOCARTA_TPO SIGNALING PATHWAY | 23 | -0.59 | -1.48 | 0.060 | 0.300 | 1.000 | 2193 | tags=39%, list=10%, signal=43% | |
| 58 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | 12 | -0.68 | -1.47 | 0.070 | 0.304 | 1.000 | 2177 | tags=42%, list=10%, signal=46% | |
| 59 | BIOCARTA_AGRIN IN POSTSYNAPTIC DIFFERENTIATION | 44 | -0.52 | -1.46 | 0.035 | 0.318 | 1.000 | 2815 | tags=25%, list=13%, signal=29% | |
| 60 | NCI_TCR SIGNALING IN NAÔVE CD8+ T CELLS | 108 | -0.45 | -1.46 | 0.018 | 0.314 | 1.000 | 2535 | tags=30%, list=12%, signal=33% | |
| 61 | REACTOME_MITOTIC_PROMETAPHASE | 38 | -0.55 | -1.46 | 0.050 | 0.312 | 1.000 | 2207 | tags=32%, list=10%, signal=35% | |
| 62 | NCI_CALCINEURIN-REGULATED NFAT-DEPENDENT TRANSCRIPTION IN LYMPHOCYTES | 43 | -0.52 | -1.46 | 0.046 | 0.314 | 1.000 | 1925 | tags=21%, list=9%, signal=23% | |
| 63 | NCI_E-CADHERIN SIGNALING IN THE NASCENT ADHERENS JUNCTION | 43 | -0.52 | -1.45 | 0.043 | 0.332 | 1.000 | 2286 | tags=26%, list=10%, signal=29% | |
| 64 | BIOCARTA_Y BRANCHING OF ACTIN FILAMENTS | 16 | -0.64 | -1.45 | 0.067 | 0.330 | 1.000 | 1192 | tags=19%, list=5%, signal=20% | |
| 65 | BIOCARTA_PHOSPHORYLATION OF MEK1 BY CDK5/P35 DOWN REGULATES THE MAP KINASE PATHWAY | 13 | -0.67 | -1.45 | 0.094 | 0.326 | 1.000 | 2193 | tags=31%, list=10%, signal=34% | |
| 66 | NCI_ALPHA-SYNUCLEIN SIGNALING | 31 | -0.57 | -1.45 | 0.058 | 0.321 | 1.000 | 3224 | tags=32%, list=15%, signal=38% | |
| 67 | NCI_GLYPICAN 1 NETWORK | 384 | -0.39 | -1.45 | 0.002 | 0.320 | 1.000 | 2545 | tags=22%, list=12%, signal=25% | |
| 68 | NCI_FAS SIGNALING PATHWAY (CD95) | 32 | -0.56 | -1.44 | 0.064 | 0.325 | 1.000 | 2177 | tags=31%, list=10%, signal=35% | |
| 69 | NCI_CLASS I PI3K SIGNALING EVENTS | 217 | -0.41 | -1.43 | 0.006 | 0.339 | 1.000 | 2545 | tags=24%, list=12%, signal=27% | |
| 70 | BIOCARTA_FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 27 | -0.57 | -1.43 | 0.067 | 0.345 | 1.000 | 2440 | tags=37%, list=11%, signal=42% | |
| 71 | REACTOME_DEATH_RECEPTOR__SIGNALLING | 12 | -0.68 | -1.43 | 0.078 | 0.347 | 1.000 | 2177 | tags=42%, list=10%, signal=46% | |
| 72 | NETPATH_BCR | 121 | -0.43 | -1.42 | 0.020 | 0.351 | 1.000 | 2394 | tags=26%, list=11%, signal=30% | |
| 73 | NCI_BMP RECEPTOR SIGNALING | 197 | -0.41 | -1.42 | 0.007 | 0.365 | 1.000 | 2198 | tags=22%, list=10%, signal=24% | |
| 74 | NETPATH_EPO | 37 | -0.53 | -1.41 | 0.057 | 0.372 | 1.000 | 3600 | tags=49%, list=16%, signal=58% | |
| 75 | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 | 23 | -0.57 | -1.41 | 0.069 | 0.369 | 1.000 | 4123 | tags=39%, list=19%, signal=48% | |
| 76 | NCI_TGF-BETA RECEPTOR SIGNALING | 262 | -0.39 | -1.40 | 0.008 | 0.380 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 77 | NCI_IFN-GAMMA PATHWAY | 334 | -0.38 | -1.40 | 0.003 | 0.376 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 78 | REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS | 48 | -0.49 | -1.40 | 0.047 | 0.380 | 1.000 | 482 | tags=19%, list=2%, signal=19% | |
| 79 | INOH_BETA CATENIN DEGRADATION SIGNALING (MAMMAL) | 20 | -0.58 | -1.40 | 0.099 | 0.378 | 1.000 | 3065 | tags=40%, list=14%, signal=46% | |
| 80 | NCI_REGULATION OF NUCLEAR SMAD2/3 SIGNALING | 262 | -0.39 | -1.40 | 0.005 | 0.377 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 81 | REACTOME_CDC20_PHOSPHO_APC_C_MEDIATED_DEGRADATION_OF_CYCLIN_A | 43 | -0.51 | -1.40 | 0.049 | 0.376 | 1.000 | 978 | tags=21%, list=4%, signal=22% | |
| 82 | BIOCARTA_MECHANISM OF GENE REGULATION BY PEROXISOME PROLIFERATORS VIA PPARA | 36 | -0.52 | -1.39 | 0.066 | 0.377 | 1.000 | 2331 | tags=28%, list=11%, signal=31% | |
| 83 | BIOCARTA_THE 41BB-DEPENDENT IMMUNE RESPONSE | 11 | -0.66 | -1.39 | 0.101 | 0.378 | 1.000 | 3429 | tags=45%, list=16%, signal=54% | |
| 84 | REACTOME_M_PHASE | 40 | -0.50 | -1.39 | 0.069 | 0.374 | 1.000 | 2207 | tags=30%, list=10%, signal=33% | |
| 85 | NCI_REGULATION OF CYTOPLASMIC AND NUCLEAR SMAD2/3 SIGNALING | 262 | -0.39 | -1.39 | 0.005 | 0.380 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 86 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | 40 | -0.51 | -1.38 | 0.061 | 0.388 | 1.000 | 356 | tags=18%, list=2%, signal=18% | |
| 87 | NCI_FC-EPSILON RECEPTOR I SIGNALING IN MAST CELLS | 54 | -0.48 | -1.38 | 0.065 | 0.388 | 1.000 | 2440 | tags=30%, list=11%, signal=33% | |
| 88 | NCI_FOXA1 TRANSCRIPTION FACTOR NETWORK | 35 | -0.51 | -1.38 | 0.065 | 0.387 | 1.000 | 2201 | tags=23%, list=10%, signal=25% | |
| 89 | BIOCARTA_FAS SIGNALING PATHWAY (CD95) | 19 | -0.59 | -1.38 | 0.098 | 0.384 | 1.000 | 2177 | tags=37%, list=10%, signal=41% | |
| 90 | BIOCARTA_ROLE OF MEF2D IN T-CELL APOPTOSIS | 25 | -0.55 | -1.37 | 0.089 | 0.387 | 1.000 | 2535 | tags=40%, list=12%, signal=45% | |
| 91 | REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS | 14 | -0.62 | -1.37 | 0.100 | 0.389 | 1.000 | 2391 | tags=36%, list=11%, signal=40% | |
| 92 | NCI_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT | 26 | -0.55 | -1.37 | 0.094 | 0.388 | 1.000 | 682 | tags=19%, list=3%, signal=20% | |
| 93 | BIOCARTA_TNFR1 SIGNALING PATHWAY | 17 | -0.60 | -1.37 | 0.107 | 0.391 | 1.000 | 2177 | tags=29%, list=10%, signal=33% | |
| 94 | BIOCARTA_BIOACTIVE PEPTIDE INDUCED SIGNALING PATHWAY | 32 | -0.52 | -1.37 | 0.076 | 0.389 | 1.000 | 3091 | tags=38%, list=14%, signal=44% | |
| 95 | INOH_SIGNALING WITHOUT WNT (MAMMAL) | 25 | -0.53 | -1.36 | 0.102 | 0.401 | 1.000 | 3879 | tags=40%, list=18%, signal=49% | |
| 96 | REACTOME_VPU_MEDIATED_DEGRADATION_OF_CD4 | 36 | -0.50 | -1.36 | 0.081 | 0.399 | 1.000 | 356 | tags=19%, list=2%, signal=20% | |
| 97 | NCI_IL1-MEDIATED SIGNALING EVENTS | 187 | -0.40 | -1.36 | 0.026 | 0.401 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 98 | INOH_T CELL RECEPTOR SIGNALING PATHWAY | 52 | -0.47 | -1.35 | 0.082 | 0.406 | 1.000 | 2331 | tags=23%, list=11%, signal=26% | |
| 99 | BIOCARTA_BCR SIGNALING PATHWAY | 29 | -0.52 | -1.35 | 0.093 | 0.402 | 1.000 | 2193 | tags=28%, list=10%, signal=31% | |
| 100 | BIOCARTA_ER ASSOCIATED DEGRADATION (ERAD) PATHWAY | 16 | -0.60 | -1.35 | 0.097 | 0.404 | 1.000 | 2324 | tags=38%, list=11%, signal=42% | |
| 101 | INOH_CANONICAL NOTCH SIGNALING PATHWAY | 25 | -0.54 | -1.34 | 0.118 | 0.413 | 1.000 | 3210 | tags=40%, list=15%, signal=47% | |
| 102 | NCI_IL6-MEDIATED SIGNALING EVENTS | 43 | -0.50 | -1.34 | 0.081 | 0.414 | 1.000 | 2650 | tags=30%, list=12%, signal=34% | |
| 103 | CELLMAP_NOTCH | 48 | -0.47 | -1.34 | 0.097 | 0.415 | 1.000 | 3210 | tags=33%, list=15%, signal=39% | |
| 104 | CELLMAP_TNF ALPHA/NF-KB | 156 | -0.40 | -1.34 | 0.029 | 0.414 | 1.000 | 2724 | tags=25%, list=12%, signal=28% | |
| 105 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND ERK CASCADE) | 33 | -0.51 | -1.34 | 0.113 | 0.411 | 1.000 | 2193 | tags=27%, list=10%, signal=30% | |
| 106 | INOH_NOTCH SECRETORY PATHWAY | 25 | -0.54 | -1.34 | 0.120 | 0.408 | 1.000 | 3210 | tags=40%, list=15%, signal=47% | |
| 107 | NCI_ANDROGEN-MEDIATED SIGNALING | 105 | -0.42 | -1.34 | 0.047 | 0.405 | 1.000 | 2195 | tags=25%, list=10%, signal=27% | |
| 108 | BIOCARTA_GATA3 PARTICIPATE IN ACTIVATING THE TH2 CYTOKINE GENES EXPRESSION | 18 | -0.57 | -1.33 | 0.133 | 0.409 | 1.000 | 562 | tags=17%, list=3%, signal=17% | |
| 109 | NCI_BCR SIGNALING PATHWAY | 63 | -0.45 | -1.33 | 0.063 | 0.414 | 1.000 | 2389 | tags=24%, list=11%, signal=27% | |
| 110 | BIOCARTA_METS AFFECT ON MACROPHAGE DIFFERENTIATION | 17 | -0.58 | -1.33 | 0.137 | 0.413 | 1.000 | 1063 | tags=18%, list=5%, signal=19% | |
| 111 | NCI_PAXILLIN-INDEPENDENT EVENTS MEDIATED BY A4B1 AND A4B7 | 22 | -0.55 | -1.33 | 0.139 | 0.410 | 1.000 | 1517 | tags=23%, list=7%, signal=24% | |
| 112 | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) | 44 | -0.48 | -1.33 | 0.095 | 0.406 | 1.000 | 4049 | tags=39%, list=18%, signal=47% | |
| 113 | REACTOME_OPIOID_SIGNALLING | 23 | -0.54 | -1.33 | 0.147 | 0.410 | 1.000 | 3862 | tags=43%, list=18%, signal=53% | |
| 114 | HUMANCYC_DE NOVO BIOSYNTHESIS OF PYRIMIDINE DEOXYRIBONUCLEOTIDES | 12 | -0.62 | -1.32 | 0.134 | 0.424 | 1.000 | 984 | tags=25%, list=4%, signal=26% | |
| 115 | BIOCARTA_P38 MAPK SIGNALING PATHWAY | 28 | -0.51 | -1.31 | 0.135 | 0.434 | 1.000 | 1723 | tags=36%, list=8%, signal=39% | |
| 116 | INOH_ERK CASCADE | 14 | -0.60 | -1.31 | 0.138 | 0.446 | 1.000 | 2193 | tags=29%, list=10%, signal=32% | |
| 117 | INOH_RAF ACTIVATION SIGNALING (THROUGH RASGRP) | 10 | -0.63 | -1.30 | 0.207 | 0.458 | 1.000 | 2193 | tags=40%, list=10%, signal=44% | |
| 118 | NCI_SYNDECAN-1-MEDIATED SIGNALING EVENTS | 157 | -0.38 | -1.30 | 0.045 | 0.461 | 1.000 | 2198 | tags=22%, list=10%, signal=24% | |
| 119 | NETPATH_IL4 | 44 | -0.47 | -1.30 | 0.129 | 0.458 | 1.000 | 3581 | tags=34%, list=16%, signal=41% | |
| 120 | NCI_PROTEOGYLCAN SYNDECAN-MEDIATED SIGNALING EVENTS | 241 | -0.37 | -1.30 | 0.028 | 0.455 | 1.000 | 2198 | tags=20%, list=10%, signal=22% | |
| 121 | NCI_ANGIOPOIETIN RECEPTOR TIE2-MEDIATED SIGNALING | 46 | -0.47 | -1.30 | 0.113 | 0.451 | 1.000 | 2331 | tags=28%, list=11%, signal=32% | |
| 122 | INOH_GROWTH HORMONE SIGNALING PATHWAY(JAK2 STAT5) | 10 | -0.63 | -1.29 | 0.198 | 0.462 | 1.000 | 1888 | tags=20%, list=9%, signal=22% | |
| 123 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY THE MAPK PATHWAY | 33 | -0.49 | -1.29 | 0.132 | 0.460 | 1.000 | 3584 | tags=33%, list=16%, signal=40% | |
| 124 | BIOCARTA_HYPOXIA-INDUCIBLE FACTOR IN THE CARDIVASCULAR SYSTEM | 13 | -0.61 | -1.29 | 0.164 | 0.464 | 1.000 | 2080 | tags=23%, list=9%, signal=25% | |
| 125 | REACTOME_APOPTOTIC_EXECUTION__PHASE | 31 | -0.50 | -1.29 | 0.137 | 0.464 | 1.000 | 341 | tags=13%, list=2%, signal=13% | |
| 126 | INOH_B-RAF ACTIVATION SIGNALING | 29 | -0.50 | -1.28 | 0.159 | 0.479 | 1.000 | 4734 | tags=45%, list=22%, signal=57% | |
| 127 | REACTOME_PI3K_AKT_SIGNALLING | 13 | -0.58 | -1.27 | 0.185 | 0.487 | 1.000 | 2347 | tags=46%, list=11%, signal=52% | |
| 128 | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | 24 | -0.51 | -1.27 | 0.159 | 0.497 | 1.000 | 3005 | tags=38%, list=14%, signal=43% | |
| 129 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | 25 | -0.50 | -1.27 | 0.154 | 0.494 | 1.000 | 341 | tags=12%, list=2%, signal=12% | |
| 130 | BIOCARTA_NFKB ACTIVATION BY NONTYPEABLE HEMOPHILUS INFLUENZAE | 28 | -0.50 | -1.27 | 0.157 | 0.494 | 1.000 | 2331 | tags=25%, list=11%, signal=28% | |
| 131 | NCI_IGF1 PATHWAY | 132 | -0.39 | -1.26 | 0.083 | 0.496 | 1.000 | 2198 | tags=20%, list=10%, signal=23% | |
| 132 | BIOCARTA_INHIBITION OF CELLULAR PROLIFERATION BY GLEEVEC | 22 | -0.52 | -1.26 | 0.178 | 0.500 | 1.000 | 2193 | tags=36%, list=10%, signal=40% | |
| 133 | INOH_CD4 T CELL RECEPTOR SIGNALING (THROUGH VAV, RAC AND JNK CASCADE | 36 | -0.47 | -1.26 | 0.149 | 0.497 | 1.000 | 1700 | tags=19%, list=8%, signal=21% | |
| 134 | REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION1 | 35 | -0.47 | -1.26 | 0.161 | 0.495 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 135 | REACTOME_REGULATION_OF_ACTIVATED_PAK_2P34_BY_PROTEASOME_MEDIATED_DEGRADATION | 36 | -0.47 | -1.26 | 0.152 | 0.496 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 136 | BIOCARTA_EGF SIGNALING PATHWAY | 19 | -0.53 | -1.26 | 0.184 | 0.492 | 1.000 | 1388 | tags=32%, list=6%, signal=34% | |
| 137 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | 37 | -0.47 | -1.26 | 0.157 | 0.491 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 138 | REACTOME_REGULATION_OF_APOPTOSIS | 37 | -0.46 | -1.25 | 0.169 | 0.494 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 139 | NCI_SIGNALING EVENTS ACTIVATED BY HEPATOCYTE GROWTH FACTOR RECEPTOR (C-MET) | 149 | -0.37 | -1.25 | 0.090 | 0.493 | 1.000 | 2198 | tags=21%, list=10%, signal=24% | |
| 140 | INOH_B CELL RECEPTOR SIGNALING PATHWAY | 71 | -0.42 | -1.25 | 0.130 | 0.494 | 1.000 | 3600 | tags=30%, list=16%, signal=35% | |
| 141 | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | 36 | -0.47 | -1.25 | 0.168 | 0.497 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 142 | BIOCARTA_ANGIOTENSIN II MEDIATED ACTIVATION OF JNK PATHWAY VIA PYK2 DEPENDENT SIGNALING | 32 | -0.48 | -1.25 | 0.158 | 0.495 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 143 | REACTOME_SIGNALING_BY_WNT | 38 | -0.45 | -1.25 | 0.139 | 0.494 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 144 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (MAMMAL) | 29 | -0.49 | -1.25 | 0.189 | 0.491 | 1.000 | 3065 | tags=28%, list=14%, signal=32% | |
| 145 | REACTOME_STABILIZATION_OF_P53 | 38 | -0.46 | -1.24 | 0.177 | 0.494 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 146 | REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D | 37 | -0.46 | -1.24 | 0.165 | 0.493 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 147 | INOH_NOTCH SECRETORY PATHWAY (MAMMAL) | 22 | -0.50 | -1.24 | 0.182 | 0.494 | 1.000 | 844 | tags=23%, list=4%, signal=24% | |
| 148 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP AND EPAC) | 25 | -0.50 | -1.24 | 0.192 | 0.495 | 1.000 | 3600 | tags=36%, list=16%, signal=43% | |
| 149 | REACTOME_UBIQUITIN_DEPENDENT_DEGRADATION_OF_CYCLIN_D1 | 37 | -0.46 | -1.24 | 0.151 | 0.492 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 150 | NCI_EPO SIGNALING PATHWAY | 31 | -0.48 | -1.23 | 0.178 | 0.500 | 1.000 | 3918 | tags=42%, list=18%, signal=51% | |
| 151 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE__ODC_ | 38 | -0.46 | -1.23 | 0.162 | 0.498 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 152 | NCI_ARF6 TRAFFICKING EVENTS | 120 | -0.38 | -1.23 | 0.117 | 0.499 | 1.000 | 2198 | tags=21%, list=10%, signal=23% | |
| 153 | NCI_INSULIN PATHWAY | 120 | -0.38 | -1.23 | 0.105 | 0.496 | 1.000 | 2198 | tags=21%, list=10%, signal=23% | |
| 154 | CELLMAP_EGFR1 | 122 | -0.38 | -1.23 | 0.091 | 0.496 | 1.000 | 2650 | tags=25%, list=12%, signal=29% | |
| 155 | NCI_IL12 SIGNALING MEDIATED BY STAT4 | 27 | -0.49 | -1.23 | 0.201 | 0.497 | 1.000 | 2535 | tags=30%, list=12%, signal=33% | |
| 156 | NCI_ENDOTHELINS | 151 | -0.37 | -1.23 | 0.101 | 0.496 | 1.000 | 2198 | tags=17%, list=10%, signal=19% | |
| 157 | REACTOME_REGULATION_OF_APC_C_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE | 47 | -0.44 | -1.23 | 0.181 | 0.494 | 1.000 | 482 | tags=17%, list=2%, signal=17% | |
| 158 | CELLMAP_TGFBR | 105 | -0.38 | -1.23 | 0.101 | 0.494 | 1.000 | 2080 | tags=21%, list=9%, signal=23% | |
| 159 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | 38 | -0.45 | -1.22 | 0.184 | 0.492 | 1.000 | 356 | tags=16%, list=2%, signal=16% | |
| 160 | NETPATH_CD40 | 29 | -0.48 | -1.22 | 0.200 | 0.494 | 1.000 | 2717 | tags=41%, list=12%, signal=47% | |
| 161 | NCI_ARF6 SIGNALING EVENTS | 120 | -0.38 | -1.22 | 0.118 | 0.495 | 1.000 | 2198 | tags=21%, list=10%, signal=23% | |
| 162 | INOH_MAMMALIAN NOTCH SIGNALING PATHWAY | 22 | -0.50 | -1.21 | 0.208 | 0.507 | 1.000 | 844 | tags=23%, list=4%, signal=24% | |
| 163 | NETPATH_GDNF | 29 | -0.48 | -1.21 | 0.208 | 0.505 | 1.000 | 4895 | tags=45%, list=22%, signal=58% | |
| 164 | NCI_PRESENILIN ACTION IN NOTCH AND WNT SIGNALING | 41 | -0.43 | -1.21 | 0.182 | 0.502 | 1.000 | 3058 | tags=34%, list=14%, signal=40% | |
| 165 | NCI_PDGFR-ALPHA SIGNALING PATHWAY | 21 | -0.50 | -1.21 | 0.190 | 0.502 | 1.000 | 1494 | tags=24%, list=7%, signal=26% | |
| 166 | BIOCARTA_ACTIVATION OF CSK BY CAMP-DEPENDENT PROTEIN KINASE INHIBITS SIGNALING THROUGH THE T CELL RECEPTOR | 36 | -0.45 | -1.21 | 0.183 | 0.500 | 1.000 | 2740 | tags=25%, list=12%, signal=29% | |
| 167 | NCI_REELIN SIGNALING PATHWAY | 27 | -0.47 | -1.21 | 0.199 | 0.500 | 1.000 | 2268 | tags=26%, list=10%, signal=29% | |
| 168 | INOH_P38 CASCADE | 12 | -0.57 | -1.21 | 0.221 | 0.497 | 1.000 | 1010 | tags=25%, list=5%, signal=26% | |
| 169 | REACTOME_M_G1_TRANSITION | 47 | -0.43 | -1.21 | 0.186 | 0.498 | 1.000 | 356 | tags=15%, list=2%, signal=15% | |
| 170 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | 18 | -0.51 | -1.21 | 0.229 | 0.495 | 1.000 | 2193 | tags=39%, list=10%, signal=43% | |
| 171 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | 39 | -0.45 | -1.21 | 0.205 | 0.494 | 1.000 | 356 | tags=15%, list=2%, signal=16% | |
| 172 | REACTOME_LOSS_OF_PROTEINS_REQUIRED_FOR_INTERPHASE_MICROTUBULE_ORGANIZATION_FROM_THE_CENTROSOME | 38 | -0.43 | -1.21 | 0.183 | 0.496 | 1.000 | 4666 | tags=39%, list=21%, signal=50% | |
| 173 | CELLMAP_WNT | 66 | -0.40 | -1.20 | 0.164 | 0.495 | 1.000 | 3058 | tags=24%, list=14%, signal=28% | |
| 174 | REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | 40 | -0.44 | -1.20 | 0.194 | 0.493 | 1.000 | 356 | tags=15%, list=2%, signal=15% | |
| 175 | BIOCARTA_NFAT AND HYPERTROPHY OF THE HEART | 42 | -0.44 | -1.20 | 0.195 | 0.498 | 1.000 | 971 | tags=14%, list=4%, signal=15% | |
| 176 | REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX | 47 | -0.43 | -1.20 | 0.202 | 0.502 | 1.000 | 356 | tags=15%, list=2%, signal=15% | |
| 177 | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | 21 | -0.50 | -1.20 | 0.216 | 0.500 | 1.000 | 1312 | tags=24%, list=6%, signal=25% | |
| 178 | BIOCARTA_INTERNAL RIBOSOME ENTRY PATHWAY | 15 | -0.54 | -1.20 | 0.225 | 0.500 | 1.000 | 2347 | tags=27%, list=11%, signal=30% | |
| 179 | BIOCARTA_NERVE GROWTH FACTOR PATHWAY (NGF) | 16 | -0.53 | -1.19 | 0.227 | 0.501 | 1.000 | 2193 | tags=31%, list=10%, signal=35% | |
| 180 | BIOCARTA_CONTROL OF SKELETAL MYOGENESIS BY HDAC AND CALCIUM/CALMODULIN-DEPENDENT KINASE (CAMK) | 19 | -0.50 | -1.19 | 0.221 | 0.505 | 1.000 | 4451 | tags=58%, list=20%, signal=73% | |
| 181 | NCI_REGULATION OF ANDROGEN RECEPTOR ACTIVITY | 84 | -0.38 | -1.19 | 0.171 | 0.509 | 1.000 | 2195 | tags=24%, list=10%, signal=26% | |
| 182 | REACTOME_METABOLISM_OF_MRNA | 21 | -0.50 | -1.18 | 0.261 | 0.518 | 1.000 | 1312 | tags=24%, list=6%, signal=25% | |
| 183 | REACTOME_APOPTOSIS | 96 | -0.37 | -1.18 | 0.159 | 0.521 | 1.000 | 2545 | tags=23%, list=12%, signal=26% | |
| 184 | REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | 37 | -0.43 | -1.18 | 0.210 | 0.525 | 1.000 | 3547 | tags=41%, list=16%, signal=48% | |
| 185 | REACTOME_EGFR_DOWNREGULATION | 11 | -0.57 | -1.18 | 0.291 | 0.524 | 1.000 | 2391 | tags=36%, list=11%, signal=41% | |
| 186 | BIOCARTA_TREFOIL FACTORS INITIATE MUCOSAL HEALING | 35 | -0.43 | -1.18 | 0.223 | 0.526 | 1.000 | 2347 | tags=26%, list=11%, signal=29% | |
| 187 | NCI_P38 SIGNALING MEDIATED BY MAPKAP KINASES | 21 | -0.49 | -1.17 | 0.286 | 0.535 | 1.000 | 2198 | tags=33%, list=10%, signal=37% | |
| 188 | BIOCARTA_EFFECTS OF CALCINEURIN IN KERATINOCYTE DIFFERENTIATION | 12 | -0.54 | -1.17 | 0.281 | 0.540 | 1.000 | 723 | tags=25%, list=3%, signal=26% | |
| 189 | REACTOME_MEMBRANE_TRAFFICKING | 24 | -0.48 | -1.17 | 0.236 | 0.537 | 1.000 | 5471 | tags=54%, list=25%, signal=72% | |
| 190 | INOH_PHOSPHOLIPASE C GAMMA SIGNALING | 49 | -0.41 | -1.17 | 0.217 | 0.538 | 1.000 | 2331 | tags=20%, list=11%, signal=23% | |
| 191 | BIOCARTA_ADP-RIBOSYLATION FACTOR | 18 | -0.51 | -1.16 | 0.274 | 0.535 | 1.000 | 1322 | tags=22%, list=6%, signal=24% | |
| 192 | BIOCARTA_UCALPAIN AND FRIENDS IN CELL SPREAD | 15 | -0.53 | -1.16 | 0.295 | 0.533 | 1.000 | 4770 | tags=40%, list=22%, signal=51% | |
| 193 | REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE | 36 | -0.43 | -1.16 | 0.248 | 0.539 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 194 | REACTOME_SIGNALLING_BY_NGF | 64 | -0.39 | -1.16 | 0.220 | 0.539 | 1.000 | 2740 | tags=27%, list=12%, signal=30% | |
| 195 | INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE) | 26 | -0.46 | -1.16 | 0.273 | 0.541 | 1.000 | 2331 | tags=23%, list=11%, signal=26% | |
| 196 | BIOCARTA_MULTIPLE ANTIAPOPTOTIC PATHWAYS FROM IGF-1R SIGNALING LEAD TO BAD PHOSPHORYLATION | 13 | -0.53 | -1.15 | 0.267 | 0.544 | 1.000 | 2193 | tags=23%, list=10%, signal=26% | |
| 197 | BIOCARTA_PROTEIN KINASE A AT THE CENTROSOME | 10 | -0.55 | -1.15 | 0.322 | 0.545 | 1.000 | 4834 | tags=50%, list=22%, signal=64% | |
| 198 | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | 36 | -0.43 | -1.15 | 0.261 | 0.543 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 199 | BIOCARTA_APOPTOTIC DNA-FRAGMENTATION AND TISSUE HOMEOSTASIS | 10 | -0.57 | -1.15 | 0.309 | 0.542 | 1.000 | 2062 | tags=40%, list=9%, signal=44% | |
| 200 | REACTOME_UBIQUITIN_MEDIATED_DEGRADATION_OF_PHOSPHORYLATED_CDC25A | 36 | -0.43 | -1.15 | 0.258 | 0.545 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 201 | BIOCARTA_ERK1/ERK2 MAPK SIGNALING PATHWAY | 21 | -0.48 | -1.15 | 0.258 | 0.545 | 1.000 | 2656 | tags=29%, list=12%, signal=32% | |
| 202 | REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE__POSTSYNAPTIC_CELL | 23 | -0.47 | -1.15 | 0.270 | 0.546 | 1.000 | 3043 | tags=35%, list=14%, signal=40% | |
| 203 | NCI_TRK RECEPTOR SIGNALING MEDIATED BY PI3K AND PLC-GAMMA | 57 | -0.39 | -1.15 | 0.251 | 0.545 | 1.000 | 2682 | tags=26%, list=12%, signal=30% | |
| 204 | BIOCARTA_CELL TO CELL ADHESION SIGNALING | 12 | -0.54 | -1.15 | 0.298 | 0.543 | 1.000 | 5263 | tags=50%, list=24%, signal=66% | |
| 205 | REACTOME_DOWNSTREAM_TCR_SIGNALING | 20 | -0.48 | -1.14 | 0.301 | 0.554 | 1.000 | 2535 | tags=35%, list=12%, signal=40% | |
| 206 | BIOCARTA_RHO CELL MOTILITY SIGNALING PATHWAY | 26 | -0.46 | -1.14 | 0.281 | 0.558 | 1.000 | 5187 | tags=58%, list=24%, signal=75% | |
| 207 | NCI_NONGENOTROPIC ANDROGEN SIGNALING | 24 | -0.46 | -1.14 | 0.286 | 0.556 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 208 | INOH_BETA CATENIN DEGRADATION SIGNALING (CANONICAL) | 24 | -0.46 | -1.14 | 0.285 | 0.555 | 1.000 | 3065 | tags=33%, list=14%, signal=39% | |
| 209 | NCI_NEUROTROPHIC FACTOR-MEDIATED TRK RECEPTOR SIGNALING | 93 | -0.36 | -1.13 | 0.232 | 0.561 | 1.000 | 2745 | tags=25%, list=13%, signal=28% | |
| 210 | NETPATH_IFN-ALPHA | 44 | -0.41 | -1.13 | 0.273 | 0.561 | 1.000 | 2331 | tags=32%, list=11%, signal=36% | |
| 211 | NCI_FOXA TRANSCRIPTION FACTOR NETWORKS | 66 | -0.37 | -1.13 | 0.256 | 0.564 | 1.000 | 2201 | tags=21%, list=10%, signal=24% | |
| 212 | BIOCARTA_TGF BETA SIGNALING PATHWAY | 20 | -0.46 | -1.13 | 0.295 | 0.566 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 213 | BIOCARTA_REGULATION OF PGC-1A | 18 | -0.49 | -1.13 | 0.287 | 0.564 | 1.000 | 3237 | tags=33%, list=15%, signal=39% | |
| 214 | BIOCARTA_IL-2 RECEPTOR BETA CHAIN IN T CELL ACTIVATION | 46 | -0.40 | -1.12 | 0.277 | 0.563 | 1.000 | 2193 | tags=26%, list=10%, signal=29% | |
| 215 | NCI_OSTEOPONTIN-MEDIATED EVENTS | 29 | -0.44 | -1.12 | 0.316 | 0.571 | 1.000 | 2665 | tags=31%, list=12%, signal=35% | |
| 216 | BIOCARTA_RAC1 CELL MOTILITY SIGNALING PATHWAY | 30 | -0.42 | -1.12 | 0.290 | 0.573 | 1.000 | 5187 | tags=47%, list=24%, signal=61% | |
| 217 | NCI_RETINOIC ACID RECEPTORS-MEDIATED SIGNALING | 38 | -0.41 | -1.11 | 0.296 | 0.585 | 1.000 | 2193 | tags=26%, list=10%, signal=29% | |
| 218 | INOH_JNK CASCADE | 16 | -0.50 | -1.11 | 0.337 | 0.583 | 1.000 | 1010 | tags=19%, list=5%, signal=20% | |
| 219 | REACTOME_CD28_CO_STIMULATION | 13 | -0.51 | -1.11 | 0.334 | 0.583 | 1.000 | 1700 | tags=31%, list=8%, signal=33% | |
| 220 | NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY | 120 | -0.34 | -1.11 | 0.264 | 0.589 | 1.000 | 2683 | tags=23%, list=12%, signal=25% | |
| 221 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | 78 | -0.36 | -1.11 | 0.295 | 0.589 | 1.000 | 1700 | tags=19%, list=8%, signal=21% | |
| 222 | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 | 36 | -0.41 | -1.10 | 0.338 | 0.588 | 1.000 | 356 | tags=17%, list=2%, signal=17% | |
| 223 | NCI_INSULIN-MEDIATED GLUCOSE TRANSPORT | 24 | -0.45 | -1.10 | 0.322 | 0.586 | 1.000 | 3069 | tags=33%, list=14%, signal=39% | |
| 224 | BIOCARTA_LINKS BETWEEN PYK2 AND MAP KINASES | 25 | -0.45 | -1.10 | 0.336 | 0.587 | 1.000 | 2193 | tags=24%, list=10%, signal=27% | |
| 225 | BIOCARTA_ERK AND PI-3 KINASE ARE NECESSARY FOR COLLAGEN BINDING IN CORNEAL EPITHELIA | 30 | -0.43 | -1.10 | 0.335 | 0.588 | 1.000 | 5263 | tags=60%, list=24%, signal=79% | |
| 226 | BIOCARTA_RAS-INDEPENDENT PATHWAY IN NK CELL-MEDIATED CYTOTOXICITY | 19 | -0.47 | -1.10 | 0.369 | 0.594 | 1.000 | 2193 | tags=21%, list=10%, signal=23% | |
| 227 | REACTOME_CREB_PHOPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | 15 | -0.49 | -1.10 | 0.346 | 0.596 | 1.000 | 3043 | tags=27%, list=14%, signal=31% | |
| 228 | BIOCARTA_LISSENCEPHALY GENE (LIS1) IN NEURONAL MIGRATION AND DEVELOPMENT | 15 | -0.50 | -1.10 | 0.380 | 0.595 | 1.000 | 172 | tags=13%, list=1%, signal=13% | |
| 229 | REACTOME_P53_DEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | 40 | -0.40 | -1.10 | 0.330 | 0.593 | 1.000 | 356 | tags=15%, list=2%, signal=15% | |
| 230 | REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | 14 | -0.49 | -1.09 | 0.367 | 0.595 | 1.000 | 5208 | tags=57%, list=24%, signal=75% | |
| 231 | NCI_NECTIN ADHESION PATHWAY | 99 | -0.34 | -1.09 | 0.268 | 0.594 | 1.000 | 2286 | tags=21%, list=10%, signal=24% | |
| 232 | REACTOME_PYRIMIDINE_METABOLISM | 17 | -0.47 | -1.09 | 0.335 | 0.593 | 1.000 | 188 | tags=12%, list=1%, signal=12% | |
| 233 | REACTOME_SCF_SKP2__MEDIATED_DEGRADATION_OF_P27_P21 | 39 | -0.40 | -1.09 | 0.315 | 0.591 | 1.000 | 356 | tags=15%, list=2%, signal=16% | |
| 234 | INOH_SIGNALING WITHOUT WNT (CANONICAL) | 29 | -0.43 | -1.09 | 0.322 | 0.589 | 1.000 | 3879 | tags=34%, list=18%, signal=42% | |
| 235 | NCI_IL27-MEDIATED SIGNALING EVENTS | 24 | -0.44 | -1.09 | 0.339 | 0.590 | 1.000 | 1940 | tags=25%, list=9%, signal=27% | |
| 236 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 44 | -0.39 | -1.09 | 0.311 | 0.595 | 1.000 | 3069 | tags=27%, list=14%, signal=32% | |
| 237 | BIOCARTA_INTEGRIN SIGNALING PATHWAY | 33 | -0.42 | -1.09 | 0.333 | 0.593 | 1.000 | 2236 | tags=21%, list=10%, signal=24% | |
| 238 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | 40 | -0.39 | -1.09 | 0.317 | 0.591 | 1.000 | 4666 | tags=38%, list=21%, signal=48% | |
| 239 | INOH_NEGATIVE FEEDBACK REGULATION PATHWAY OF TGF BETA SUPERFAMILY SIGNALING BY (BINDING OF SMAD6/7 AND TGF BETA RECEPTOR I) | 12 | -0.51 | -1.08 | 0.394 | 0.592 | 1.000 | 1043 | tags=25%, list=5%, signal=26% | |
| 240 | NCI_P75(NTR)-MEDIATED SIGNALING | 165 | -0.32 | -1.08 | 0.278 | 0.590 | 1.000 | 2812 | tags=24%, list=13%, signal=28% | |
| 241 | NCI_EPHB FORWARD SIGNALING | 37 | -0.40 | -1.08 | 0.335 | 0.589 | 1.000 | 2193 | tags=16%, list=10%, signal=18% | |
| 242 | INOH_GENE EXPROSSION OF SMAD6/7 BY R-SMAD:SMAD4 | 12 | -0.51 | -1.08 | 0.370 | 0.593 | 1.000 | 1043 | tags=25%, list=5%, signal=26% | |
| 243 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | 40 | -0.40 | -1.08 | 0.363 | 0.595 | 1.000 | 356 | tags=15%, list=2%, signal=15% | |
| 244 | BIOCARTA_ERYTHROPOIETIN MEDIATED NEUROPROTECTION THROUGH NF-KB | 12 | -0.51 | -1.08 | 0.387 | 0.595 | 1.000 | 2331 | tags=33%, list=11%, signal=37% | |
| 245 | REACTOME_SYNAPTIC_TRANSMISSION | 44 | -0.39 | -1.08 | 0.335 | 0.596 | 1.000 | 3069 | tags=27%, list=14%, signal=32% | |
| 246 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | 19 | -0.46 | -1.07 | 0.368 | 0.596 | 1.000 | 318 | tags=16%, list=1%, signal=16% | |
| 247 | INOH_RAP1 ACTIVATION SIGNALING (THROUGH CAMP. PKA, CBL AND C3G) | 13 | -0.50 | -1.07 | 0.394 | 0.594 | 1.000 | 2232 | tags=31%, list=10%, signal=34% | |
| 248 | NCI_HYPOXIC AND OXYGEN HOMEOSTASIS REGULATION OF HIF-1-ALPHA | 66 | -0.36 | -1.07 | 0.321 | 0.595 | 1.000 | 2546 | tags=27%, list=12%, signal=31% | |
| 249 | NCI_GLYPICAN 3 NETWORK | 57 | -0.37 | -1.07 | 0.336 | 0.594 | 1.000 | 3210 | tags=25%, list=15%, signal=29% | |
| 250 | INOH_GENE EXPRESSION OF SOCS1 BY STAT DIMER | 30 | -0.41 | -1.07 | 0.357 | 0.595 | 1.000 | 1888 | tags=23%, list=9%, signal=25% | |
| 251 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 14 | -0.49 | -1.07 | 0.404 | 0.594 | 1.000 | 5208 | tags=57%, list=24%, signal=75% | |
| 252 | REACTOME_CENTROSOME_MATURATION | 40 | -0.39 | -1.07 | 0.368 | 0.594 | 1.000 | 4666 | tags=38%, list=21%, signal=48% | |
| 253 | NCI_REGULATION OF RETINOBLASTOMA PROTEIN | 60 | -0.36 | -1.07 | 0.335 | 0.594 | 1.000 | 2159 | tags=25%, list=10%, signal=28% | |
| 254 | REACTOME_CELL_JUNCTION_ORGANIZATION | 25 | -0.43 | -1.07 | 0.370 | 0.592 | 1.000 | 4248 | tags=44%, list=19%, signal=55% | |
| 255 | BIOCARTA_SEGMENTATION CLOCK | 20 | -0.44 | -1.07 | 0.398 | 0.591 | 1.000 | 3058 | tags=30%, list=14%, signal=35% | |
| 256 | BIOCARTA_IL-7 SIGNAL TRANSDUCTION | 15 | -0.48 | -1.06 | 0.361 | 0.607 | 1.000 | 2080 | tags=40%, list=9%, signal=44% | |
| 257 | INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (JAK DEGRADATION SIGNALING) | 30 | -0.41 | -1.06 | 0.372 | 0.607 | 1.000 | 1888 | tags=23%, list=9%, signal=25% | |
| 258 | BIOCARTA_STATHMIN AND BREAST CANCER RESISTANCE TO ANTIMICROTUBULE AGENTS | 16 | -0.47 | -1.06 | 0.393 | 0.607 | 1.000 | 210 | tags=13%, list=1%, signal=13% | |
| 259 | NCI_SYNDECAN-3-MEDIATED SIGNALING EVENTS | 13 | -0.48 | -1.05 | 0.393 | 0.607 | 1.000 | 2392 | tags=38%, list=11%, signal=43% | |
| 260 | BIOCARTA_CTCF: FIRST MULTIVALENT NUCLEAR FACTOR | 22 | -0.43 | -1.05 | 0.386 | 0.609 | 1.000 | 1043 | tags=23%, list=5%, signal=24% | |
| 261 | BIOCARTA_TRANSCRIPTION REGULATION BY METHYLTRANSFERASE OF CARM1 | 13 | -0.50 | -1.05 | 0.430 | 0.611 | 1.000 | 3685 | tags=54%, list=17%, signal=65% | |
| 262 | NCI_IL4-MEDIATED SIGNALING EVENTS | 57 | -0.35 | -1.05 | 0.391 | 0.621 | 1.000 | 1974 | tags=19%, list=9%, signal=21% | |
| 263 | REACTOME_SIGNALING_BY_EGFR | 28 | -0.41 | -1.04 | 0.417 | 0.621 | 1.000 | 2650 | tags=36%, list=12%, signal=41% | |
| 264 | BIOCARTA_B CELL SURVIVAL PATHWAY | 13 | -0.49 | -1.04 | 0.426 | 0.623 | 1.000 | 775 | tags=23%, list=4%, signal=24% | |
| 265 | NCI_SIGNALING MEDIATED BY P38-ALPHA AND P38-BETA | 47 | -0.38 | -1.04 | 0.411 | 0.621 | 1.000 | 2466 | tags=23%, list=11%, signal=26% | |
| 266 | REACTOME_TCR_SIGNALING | 33 | -0.40 | -1.04 | 0.384 | 0.620 | 1.000 | 2998 | tags=30%, list=14%, signal=35% | |
| 267 | INOH_PKA ACTIVATION SIGNALING | 49 | -0.37 | -1.04 | 0.398 | 0.620 | 1.000 | 2232 | tags=18%, list=10%, signal=20% | |
| 268 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (CANONICAL) | 33 | -0.40 | -1.04 | 0.415 | 0.624 | 1.000 | 3065 | tags=24%, list=14%, signal=28% | |
| 269 | CELLMAP_KITRECEPTOR | 49 | -0.36 | -1.04 | 0.394 | 0.628 | 1.000 | 2080 | tags=27%, list=9%, signal=29% | |
| 270 | BIOCARTA_IL 3 SIGNALING PATHWAY | 11 | -0.49 | -1.03 | 0.430 | 0.627 | 1.000 | 4055 | tags=36%, list=18%, signal=45% | |
| 271 | REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE | 17 | -0.45 | -1.03 | 0.413 | 0.630 | 1.000 | 1282 | tags=24%, list=6%, signal=25% | |
| 272 | INOH_CYTOSOLIC CALCIUM ION CONCENTRATION ELEVATION (THROUGH IP3 RECEPTOR) | 15 | -0.46 | -1.03 | 0.416 | 0.628 | 1.000 | 2193 | tags=20%, list=10%, signal=22% | |
| 273 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | 16 | -0.45 | -1.03 | 0.421 | 0.632 | 1.000 | 2998 | tags=38%, list=14%, signal=43% | |
| 274 | NCI_IL12-MEDIATED SIGNALING EVENTS | 101 | -0.32 | -1.03 | 0.404 | 0.635 | 1.000 | 2717 | tags=24%, list=12%, signal=27% | |
| 275 | BIOCARTA_ROLE OF ERK5 IN NEURONAL SURVIVAL PATHWAY | 24 | -0.41 | -1.02 | 0.448 | 0.650 | 1.000 | 2193 | tags=29%, list=10%, signal=32% | |
| 276 | NCI_RXR AND RAR HETERODIMERIZATION WITH OTHER NUCLEAR RECEPTOR | 19 | -0.43 | -1.02 | 0.445 | 0.650 | 1.000 | 1905 | tags=16%, list=9%, signal=17% | |
| 277 | NCI_MTOR SIGNALING PATHWAY | 23 | -0.42 | -1.02 | 0.445 | 0.649 | 1.000 | 775 | tags=13%, list=4%, signal=14% | |
| 278 | NCI_S1P2 PATHWAY | 23 | -0.41 | -1.01 | 0.455 | 0.655 | 1.000 | 3218 | tags=22%, list=15%, signal=25% | |
| 279 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | 11 | -0.48 | -1.01 | 0.459 | 0.653 | 1.000 | 3244 | tags=36%, list=15%, signal=43% | |
| 280 | NCI_HIF-1-ALPHA TRANSCRIPTION FACTOR NETWORK | 56 | -0.35 | -1.01 | 0.433 | 0.653 | 1.000 | 2546 | tags=29%, list=12%, signal=32% | |
| 281 | REACTOME_DEADENYLATION_OF_MRNA | 10 | -0.49 | -1.01 | 0.472 | 0.652 | 1.000 | 608 | tags=20%, list=3%, signal=21% | |
| 282 | INOH_G ALPHA S GDP-GTP EXCHANGE SIGNALING | 107 | -0.31 | -1.01 | 0.409 | 0.650 | 1.000 | 3685 | tags=20%, list=17%, signal=23% | |
| 283 | BIOCARTA_RAS SIGNALING PATHWAY | 19 | -0.43 | -1.01 | 0.438 | 0.656 | 1.000 | 2347 | tags=26%, list=11%, signal=29% | |
| 284 | BIOCARTA_PROTEASOME COMPLEX | 23 | -0.41 | -1.01 | 0.468 | 0.657 | 1.000 | 182 | tags=13%, list=1%, signal=13% | |
| 285 | BIOCARTA_PTEN DEPENDENT CELL CYCLE ARREST AND APOPTOSIS | 14 | -0.46 | -1.00 | 0.470 | 0.664 | 1.000 | 775 | tags=14%, list=4%, signal=15% | |
| 286 | NCI_IL2 SIGNALING EVENTS MEDIATED BY STAT5 | 27 | -0.39 | -1.00 | 0.456 | 0.664 | 1.000 | 1157 | tags=15%, list=5%, signal=16% | |
| 287 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1 | 12 | -0.47 | -1.00 | 0.485 | 0.662 | 1.000 | 3496 | tags=33%, list=16%, signal=40% | |
| 288 | NCI_AURORA B SIGNALING | 35 | -0.38 | -1.00 | 0.437 | 0.660 | 1.000 | 1790 | tags=20%, list=8%, signal=22% | |
| 289 | BIOCARTA_FIBRINOLYSIS PATHWAY | 12 | -0.47 | -0.99 | 0.479 | 0.670 | 1.000 | 2142 | tags=25%, list=10%, signal=28% | |
| 290 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS I | 88 | -0.32 | -0.99 | 0.486 | 0.680 | 1.000 | 2758 | tags=24%, list=13%, signal=27% | |
| 291 | BIOCARTA_REGULATION OF EIF2 | 10 | -0.48 | -0.99 | 0.497 | 0.679 | 1.000 | 840 | tags=30%, list=4%, signal=31% | |
| 292 | BIOCARTA_TOLL-LIKE RECEPTOR PATHWAY | 35 | -0.37 | -0.99 | 0.450 | 0.681 | 1.000 | 2451 | tags=20%, list=11%, signal=22% | |
| 293 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | 11 | -0.48 | -0.98 | 0.516 | 0.681 | 1.000 | 5208 | tags=55%, list=24%, signal=71% | |
| 294 | BIOCARTA_OVERVIEW OF TELOMERASE PROTEIN COMPONENT GENE HTERT TRANSCRIPTIONAL REGULATION | 10 | -0.48 | -0.98 | 0.501 | 0.683 | 1.000 | 838 | tags=20%, list=4%, signal=21% | |
| 295 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, P38 CASCADE) | 20 | -0.41 | -0.98 | 0.482 | 0.685 | 1.000 | 1010 | tags=15%, list=5%, signal=16% | |
| 296 | NCI_SYNDECAN-2-MEDIATED SIGNALING EVENTS | 72 | -0.33 | -0.98 | 0.504 | 0.687 | 1.000 | 2997 | tags=21%, list=14%, signal=24% | |
| 297 | INOH_TOLL-LIKE RECEPTOR SIGNALING PATHWAY (THROUGH ECSIT, MEKK1, MKKS, JNK CASCADE) | 19 | -0.41 | -0.98 | 0.484 | 0.685 | 1.000 | 1010 | tags=16%, list=5%, signal=17% | |
| 298 | REACTOME_GLUCOSE_METABOLISM | 56 | -0.34 | -0.98 | 0.504 | 0.690 | 1.000 | 1672 | tags=16%, list=8%, signal=17% | |
| 299 | REACTOME_CLASS_A_1__RHODOPSIN_LIKE_RECEPTORS_ | 90 | -0.31 | -0.97 | 0.504 | 0.690 | 1.000 | 1989 | tags=8%, list=9%, signal=9% | |
| 300 | NETPATH_IL9 | 10 | -0.48 | -0.97 | 0.507 | 0.688 | 1.000 | 3459 | tags=40%, list=16%, signal=47% | |
| 301 | BIOCARTA_REGULATION OF CK1/CDK5 BY TYPE 1 GLUTAMATE RECEPTORS | 23 | -0.40 | -0.97 | 0.500 | 0.687 | 1.000 | 3685 | tags=35%, list=17%, signal=42% | |
| 302 | REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | 21 | -0.40 | -0.97 | 0.484 | 0.688 | 1.000 | 3700 | tags=33%, list=17%, signal=40% | |
| 303 | REACTOME_HORMONE_BIOSYNTHESIS | 31 | -0.37 | -0.96 | 0.505 | 0.702 | 1.000 | 1643 | tags=10%, list=7%, signal=10% | |
| 304 | NCI_VEGFR3 SIGNALING IN LYMPHATIC ENDOTHELIUM | 24 | -0.39 | -0.96 | 0.532 | 0.705 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 305 | REACTOME_AXON_GUIDANCE | 55 | -0.33 | -0.95 | 0.540 | 0.720 | 1.000 | 2193 | tags=22%, list=10%, signal=24% | |
| 306 | BIOCARTA_NUCLEAR RECEPTORS COORDINATE THE ACTIVITIES OF CHROMATIN REMODELING COMPLEXES AND COACTIVATORS TO FACILITATE INITIATION OF TRANSCRIPTION IN CARCINOMA CELLS | 14 | -0.42 | -0.95 | 0.514 | 0.718 | 1.000 | 1356 | tags=36%, list=6%, signal=38% | |
| 307 | INOH_RAF ACTIVATION SIGNALING (THROUGH GRB2 AND SOS) | 12 | -0.44 | -0.95 | 0.533 | 0.716 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 308 | NCI_AURORA A SIGNALING | 60 | -0.32 | -0.95 | 0.527 | 0.728 | 1.000 | 3058 | tags=27%, list=14%, signal=31% | |
| 309 | NCI_WNT SIGNALING | 49 | -0.33 | -0.95 | 0.529 | 0.727 | 1.000 | 2415 | tags=18%, list=11%, signal=21% | |
| 310 | BIOCARTA_THE IGF-1 RECEPTOR AND LONGEVITY | 15 | -0.42 | -0.95 | 0.507 | 0.725 | 1.000 | 1483 | tags=20%, list=7%, signal=21% | |
| 311 | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | 59 | -0.32 | -0.95 | 0.555 | 0.723 | 1.000 | 1332 | tags=10%, list=6%, signal=11% | |
| 312 | NCI_CANONICAL WNT SIGNALING PATHWAY | 49 | -0.33 | -0.95 | 0.540 | 0.721 | 1.000 | 2415 | tags=18%, list=11%, signal=21% | |
| 313 | INOH_NEGATIVE FEEDBACK REGULATION OF JAK STAT PATHWAY BY (CYTOKINE RECEPTOR DEGRADATION SIGNALING) | 26 | -0.37 | -0.94 | 0.552 | 0.727 | 1.000 | 1888 | tags=23%, list=9%, signal=25% | |
| 314 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 14 | -0.42 | -0.94 | 0.562 | 0.730 | 1.000 | 294 | tags=14%, list=1%, signal=14% | |
| 315 | INOH_GENE EXPRESSION OF SOCS3 BY STAT DIMER | 26 | -0.37 | -0.94 | 0.538 | 0.728 | 1.000 | 1888 | tags=23%, list=9%, signal=25% | |
| 316 | REACTOME_PLATELET_ACTIVATION_TRIGGERS | 24 | -0.38 | -0.94 | 0.548 | 0.729 | 1.000 | 1989 | tags=25%, list=9%, signal=27% | |
| 317 | NCI_CERAMIDE SIGNALING PATHWAY | 42 | -0.34 | -0.94 | 0.581 | 0.728 | 1.000 | 2630 | tags=29%, list=12%, signal=32% | |
| 318 | BIOCARTA_WNT SIGNALING PATHWAY | 27 | -0.37 | -0.94 | 0.550 | 0.727 | 1.000 | 3058 | tags=26%, list=14%, signal=30% | |
| 319 | BIOCARTA_SIGNALING PATHWAY FROM G-PROTEIN FAMILIES | 24 | -0.38 | -0.93 | 0.561 | 0.739 | 1.000 | 3685 | tags=38%, list=17%, signal=45% | |
| 320 | HUMANCYC_RESPIRATION (ANAEROBIC) | 16 | -0.41 | -0.93 | 0.569 | 0.740 | 1.000 | 1741 | tags=19%, list=8%, signal=20% | |
| 321 | NCI_SIGNALING EVENTS MEDIATED BY VEGFR1 AND VEGFR2 | 65 | -0.31 | -0.93 | 0.588 | 0.739 | 1.000 | 1700 | tags=11%, list=8%, signal=12% | |
| 322 | NCI_INTEGRINS IN ANGIOGENESIS | 62 | -0.31 | -0.93 | 0.581 | 0.739 | 1.000 | 2665 | tags=19%, list=12%, signal=22% | |
| 323 | BIOCARTA_CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES | 15 | -0.41 | -0.93 | 0.590 | 0.738 | 1.000 | 2331 | tags=27%, list=11%, signal=30% | |
| 324 | BIOCARTA_THROMBIN SIGNALING AND PROTEASE-ACTIVATED RECEPTORS | 21 | -0.40 | -0.92 | 0.560 | 0.744 | 1.000 | 775 | tags=14%, list=4%, signal=15% | |
| 325 | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY | 132 | -0.28 | -0.92 | 0.664 | 0.749 | 1.000 | 3110 | tags=21%, list=14%, signal=25% | |
| 326 | NCI_IL23-MEDIATED SIGNALING EVENTS | 60 | -0.32 | -0.92 | 0.599 | 0.748 | 1.000 | 2717 | tags=23%, list=12%, signal=27% | |
| 327 | INOH_NEGATIVE REGULATION OF (TRANSCRIPTION BY R-SMAD:SMAD4) IN TGF BETA SUPER FAMILY SIGNALING PATHWAY | 17 | -0.40 | -0.92 | 0.575 | 0.748 | 1.000 | 5142 | tags=59%, list=23%, signal=77% | |
| 328 | BIOCARTA_CYCLINS AND CELL CYCLE REGULATION | 21 | -0.38 | -0.91 | 0.584 | 0.751 | 1.000 | 1063 | tags=24%, list=5%, signal=25% | |
| 329 | NCI_NONCANONICAL WNT SIGNALING PATHWAY | 18 | -0.40 | -0.91 | 0.586 | 0.749 | 1.000 | 1394 | tags=17%, list=6%, signal=18% | |
| 330 | NCI_FGF SIGNALING PATHWAY | 46 | -0.33 | -0.91 | 0.606 | 0.754 | 1.000 | 2815 | tags=24%, list=13%, signal=27% | |
| 331 | BIOCARTA_MAP KINASE INACTIVATION OF SMRT COREPRESSOR | 17 | -0.40 | -0.91 | 0.593 | 0.757 | 1.000 | 1324 | tags=18%, list=6%, signal=19% | |
| 332 | BIOCARTA_ASPIRIN BLOCKS SIGNALING PATHWAY INVOLVED IN PLATELET ACTIVATION | 16 | -0.41 | -0.91 | 0.576 | 0.756 | 1.000 | 2193 | tags=31%, list=10%, signal=35% | |
| 333 | BIOCARTA_CONTROL OF GENE EXPRESSION BY VITAMIN D RECEPTOR | 24 | -0.37 | -0.90 | 0.608 | 0.757 | 1.000 | 2167 | tags=33%, list=10%, signal=37% | |
| 334 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 12 | -0.42 | -0.90 | 0.586 | 0.756 | 1.000 | 1700 | tags=33%, list=8%, signal=36% | |
| 335 | NCI_SIGNALING EVENTS MEDIATED BY HDAC CLASS II | 31 | -0.35 | -0.90 | 0.621 | 0.759 | 1.000 | 2701 | tags=29%, list=12%, signal=33% | |
| 336 | HUMANCYC_NAD/NADH PHOSPHORYLATION AND DEPHOSPHORYLATION | 32 | -0.34 | -0.89 | 0.610 | 0.773 | 1.000 | 249 | tags=6%, list=1%, signal=6% | |
| 337 | REACTOME_SIGNALING_BY_GPCR | 139 | -0.27 | -0.89 | 0.710 | 0.785 | 1.000 | 1989 | tags=8%, list=9%, signal=9% | |
| 338 | HUMANCYC_TCA CYCLE | 18 | -0.38 | -0.88 | 0.631 | 0.788 | 1.000 | 1602 | tags=17%, list=7%, signal=18% | |
| 339 | NETPATH_TIE1_TEK | 25 | -0.36 | -0.88 | 0.642 | 0.794 | 1.000 | 1974 | tags=16%, list=9%, signal=18% | |
| 340 | BIOCARTA_ROLE OF FL-ARRESTINS IN THE ACTIVATION AND TARGETING OF MAP KINASES | 28 | -0.35 | -0.88 | 0.643 | 0.797 | 1.000 | 2546 | tags=21%, list=12%, signal=24% | |
| 341 | BIOCARTA_HYPOXIA AND P53 IN THE CARDIOVASCULAR SYSTEM | 19 | -0.37 | -0.88 | 0.631 | 0.799 | 1.000 | 2760 | tags=21%, list=13%, signal=24% | |
| 342 | HUMANCYC_SUPERPATHWAY OF GLYOXYLATE BYPASS AND TCA | 18 | -0.38 | -0.87 | 0.612 | 0.798 | 1.000 | 1602 | tags=17%, list=7%, signal=18% | |
| 343 | BIOCARTA_REGULATION OF CELL CYCLE PROGRESSION BY PLK3 | 17 | -0.38 | -0.87 | 0.669 | 0.801 | 1.000 | 207 | tags=12%, list=1%, signal=12% | |
| 344 | BIOCARTA_MECHANISM OF PROTEIN IMPORT INTO THE NUCLEUS | 11 | -0.41 | -0.87 | 0.664 | 0.801 | 1.000 | 1672 | tags=27%, list=8%, signal=30% | |
| 345 | BIOCARTA_NF-KB SIGNALING PATHWAY | 21 | -0.36 | -0.87 | 0.631 | 0.801 | 1.000 | 2331 | tags=24%, list=11%, signal=27% | |
| 346 | BIOCARTA_REGULATION OF P27 PHOSPHORYLATION DURING CELL CYCLE PROGRESSION | 11 | -0.41 | -0.87 | 0.647 | 0.802 | 1.000 | 3185 | tags=55%, list=15%, signal=64% | |
| 347 | BIOCARTA_MCALPAIN AND FRIENDS IN CELL MOTILITY | 28 | -0.34 | -0.87 | 0.679 | 0.804 | 1.000 | 3685 | tags=29%, list=17%, signal=34% | |
| 348 | REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES | 64 | -0.29 | -0.86 | 0.697 | 0.805 | 1.000 | 1332 | tags=9%, list=6%, signal=10% | |
| 349 | BIOCARTA_AKT SIGNALING PATHWAY | 14 | -0.39 | -0.86 | 0.650 | 0.806 | 1.000 | 2347 | tags=29%, list=11%, signal=32% | |
| 350 | BIOCARTA_PHOSPHOLIPASE C-EPSILON PATHWAY | 11 | -0.42 | -0.86 | 0.651 | 0.806 | 1.000 | 3685 | tags=45%, list=17%, signal=55% | |
| 351 | BIOCARTA_GROWTH HORMONE SIGNALING PATHWAY | 17 | -0.38 | -0.86 | 0.661 | 0.806 | 1.000 | 1888 | tags=24%, list=9%, signal=26% | |
| 352 | BIOCARTA_BONE REMODELING | 15 | -0.39 | -0.85 | 0.674 | 0.819 | 1.000 | 180 | tags=7%, list=1%, signal=7% | |
| 353 | BIOCARTA_APOPTOTIC SIGNALING IN RESPONSE TO DNA DAMAGE | 14 | -0.39 | -0.85 | 0.674 | 0.821 | 1.000 | 207 | tags=14%, list=1%, signal=14% | |
| 354 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 54 | -0.30 | -0.85 | 0.748 | 0.819 | 1.000 | 4427 | tags=19%, list=20%, signal=23% | |
| 355 | HUMANCYC_VALINE DEGRADATION I | 10 | -0.41 | -0.85 | 0.660 | 0.820 | 1.000 | 3310 | tags=40%, list=15%, signal=47% | |
| 356 | BIOCARTA_ROLES OF FL ARRESTIN DEPENDENT RECRUITMENT OF SRC KINASES IN GPCR SIGNALING | 32 | -0.32 | -0.84 | 0.716 | 0.837 | 1.000 | 2546 | tags=19%, list=12%, signal=21% | |
| 357 | HUMANCYC_PHOSPHOLIPID BIOSYNTHESIS II | 27 | -0.34 | -0.84 | 0.708 | 0.834 | 1.000 | 2699 | tags=22%, list=12%, signal=25% | |
| 358 | BIOCARTA_ROLE OF ERBB2 IN SIGNAL TRANSDUCTION AND ONCOLOGY | 28 | -0.33 | -0.83 | 0.737 | 0.840 | 1.000 | 2567 | tags=25%, list=12%, signal=28% | |
| 359 | REACTOME_TOLL_LIKE_RECEPTOR_3__TLR3__CASCADE | 15 | -0.37 | -0.82 | 0.691 | 0.854 | 1.000 | 2673 | tags=20%, list=12%, signal=23% | |
| 360 | REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | 17 | -0.36 | -0.82 | 0.712 | 0.858 | 1.000 | 3944 | tags=29%, list=18%, signal=36% | |
| 361 | NCI_EPHRINB-EPHB PATHWAY | 53 | -0.28 | -0.82 | 0.786 | 0.861 | 1.000 | 2546 | tags=17%, list=12%, signal=19% | |
| 362 | INOH_SIGNALING WITH WNT (MAMMAL) | 53 | -0.29 | -0.82 | 0.757 | 0.861 | 1.000 | 5411 | tags=34%, list=25%, signal=45% | |
| 363 | NCI_EPHA2 FORWARD SIGNALING | 17 | -0.36 | -0.81 | 0.714 | 0.861 | 1.000 | 4895 | tags=35%, list=22%, signal=45% | |
| 364 | HUMANCYC_CDP-DIACYLGLYCEROL BIOSYNTHESIS II | 10 | -0.39 | -0.81 | 0.743 | 0.872 | 1.000 | 2482 | tags=30%, list=11%, signal=34% | |
| 365 | BIOCARTA_CCR3 SIGNALING IN EOSINOPHILS | 22 | -0.33 | -0.81 | 0.762 | 0.869 | 1.000 | 2193 | tags=14%, list=10%, signal=15% | |
| 366 | BIOCARTA_SPROUTY REGULATION OF TYROSINE KINASE SIGNALS | 20 | -0.34 | -0.81 | 0.749 | 0.868 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 367 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_THE_ANTIVIRAL_CYTOKINE_IFN_ALPHA_BETA_CASCADE | 13 | -0.37 | -0.80 | 0.711 | 0.871 | 1.000 | 2673 | tags=23%, list=12%, signal=26% | |
| 368 | BIOCARTA_CELL CYCLE: G2/M CHECKPOINT | 20 | -0.34 | -0.80 | 0.758 | 0.873 | 1.000 | 3215 | tags=25%, list=15%, signal=29% | |
| 369 | BIOCARTA_HOW PROGESTERONE INITIATES THE OOCYTE MATURATION | 21 | -0.33 | -0.80 | 0.755 | 0.873 | 1.000 | 3685 | tags=33%, list=17%, signal=40% | |
| 370 | REACTOME_SIGNALLING_TO_RAS | 12 | -0.38 | -0.80 | 0.728 | 0.875 | 1.000 | 2193 | tags=25%, list=10%, signal=28% | |
| 371 | BIOCARTA_REGULATION OF TRANSCRIPTIONAL ACTIVITY BY PML | 11 | -0.38 | -0.79 | 0.737 | 0.877 | 1.000 | 2159 | tags=18%, list=10%, signal=20% | |
| 372 | REACTOME_SHC_RELATED_EVENTS | 10 | -0.39 | -0.79 | 0.740 | 0.876 | 1.000 | 2193 | tags=30%, list=10%, signal=33% | |
| 373 | HUMANCYC_CDP-DIACYLGLYCEROL BIOSYNTHESIS I | 10 | -0.39 | -0.79 | 0.740 | 0.877 | 1.000 | 2482 | tags=30%, list=11%, signal=34% | |
| 374 | NCI_THROMBOXANE A2 RECEPTOR SIGNALING | 50 | -0.27 | -0.79 | 0.837 | 0.881 | 1.000 | 3700 | tags=24%, list=17%, signal=29% | |
| 375 | BIOCARTA_INACTIVATION OF GSK3 BY AKT CAUSES ACCUMULATION OF B-CATENIN IN ALVEOLAR MACROPHAGES | 37 | -0.29 | -0.78 | 0.834 | 0.883 | 1.000 | 3310 | tags=24%, list=15%, signal=29% | |
| 376 | BIOCARTA_ROLE OF NICOTINIC ACETYLCHOLINE RECEPTORS IN THE REGULATION OF APOPTOSIS | 15 | -0.34 | -0.77 | 0.782 | 0.896 | 1.000 | 775 | tags=13%, list=4%, signal=14% | |
| 377 | REACTOME_TOLL_RECEPTOR_CASCADES | 27 | -0.30 | -0.77 | 0.829 | 0.896 | 1.000 | 2673 | tags=15%, list=12%, signal=17% | |
| 378 | HUMANCYC_SUPERPATHWAY OF CHOLESTEROL BIOSYNTHESIS | 24 | -0.30 | -0.77 | 0.796 | 0.896 | 1.000 | 2048 | tags=17%, list=9%, signal=18% | |
| 379 | REACTOME_TOLL_LIKE_RECEPTOR_4__TLR4__CASCADE | 10 | -0.37 | -0.76 | 0.762 | 0.902 | 1.000 | 2673 | tags=20%, list=12%, signal=23% | |
| 380 | NCI_LPA4-MEDIATED SIGNALING EVENTS | 14 | -0.35 | -0.76 | 0.812 | 0.902 | 1.000 | 4834 | tags=43%, list=22%, signal=55% | |
| 381 | NCI_VISUAL SIGNAL TRANSDUCTION: CONES | 16 | -0.33 | -0.75 | 0.815 | 0.910 | 1.000 | 688 | tags=6%, list=3%, signal=6% | |
| 382 | NCI_STABILIZATION AND EXPANSION OF THE E-CADHERIN ADHERENS JUNCTION | 19 | -0.32 | -0.75 | 0.819 | 0.918 | 1.000 | 3700 | tags=26%, list=17%, signal=32% | |
| 383 | BIOCARTA_TRANSCRIPTION FACTOR CREB AND ITS EXTRACELLULAR SIGNALS | 25 | -0.30 | -0.74 | 0.846 | 0.917 | 1.000 | 3685 | tags=32%, list=17%, signal=38% | |
| 384 | HUMANCYC_TRIACYLGLYCEROL DEGRADATION | 12 | -0.35 | -0.74 | 0.806 | 0.916 | 1.000 | 4169 | tags=25%, list=19%, signal=31% | |
| 385 | BIOCARTA_ENDOCYTOTIC ROLE OF NDK PHOSPHINS AND DYNAMIN | 15 | -0.33 | -0.74 | 0.826 | 0.922 | 1.000 | 3043 | tags=27%, list=14%, signal=31% | |
| 386 | BIOCARTA_PKC-CATALYZED PHOSPHORYLATION OF INHIBITORY PHOSPHOPROTEIN OF MYOSIN PHOSPHATASE | 20 | -0.31 | -0.74 | 0.847 | 0.921 | 1.000 | 3700 | tags=30%, list=17%, signal=36% | |
| 387 | REACTOME_SPHINGOLIPID_METABOLISM | 10 | -0.35 | -0.72 | 0.804 | 0.931 | 1.000 | 3521 | tags=30%, list=16%, signal=36% | |
| 388 | INOH_ADENYLATE CYCLASE ACTIVATION SIGNALING | 11 | -0.34 | -0.72 | 0.816 | 0.937 | 1.000 | 4760 | tags=45%, list=22%, signal=58% | |
| 389 | BIOCARTA_PHOSPHOLIPIDS AS SIGNALLING INTERMEDIARIES | 30 | -0.28 | -0.71 | 0.864 | 0.938 | 1.000 | 2193 | tags=13%, list=10%, signal=15% | |
| 390 | BIOCARTA_CHAPERONES MODULATE INTERFERON SIGNALING PATHWAY | 17 | -0.31 | -0.71 | 0.843 | 0.941 | 1.000 | 3480 | tags=24%, list=16%, signal=28% | |
| 391 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | 16 | -0.31 | -0.70 | 0.848 | 0.942 | 1.000 | 3067 | tags=19%, list=14%, signal=22% | |
| 392 | INOH_SIGNALING WITH WNT (CANONICAL) | 57 | -0.23 | -0.69 | 0.957 | 0.957 | 1.000 | 5411 | tags=32%, list=25%, signal=42% | |
| 393 | INOH_SIGNALING WITH WNT (XENOPUS) | 15 | -0.30 | -0.68 | 0.856 | 0.955 | 1.000 | 2227 | tags=13%, list=10%, signal=15% | |
| 394 | INOH_STABILIZATION AND ACCUMULATION OF CYTOPLASMIC BETA-CATENIN (XENOPUS) | 15 | -0.30 | -0.68 | 0.873 | 0.955 | 1.000 | 2227 | tags=13%, list=10%, signal=15% | |
| 395 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | 23 | -0.27 | -0.68 | 0.903 | 0.958 | 1.000 | 2902 | tags=17%, list=13%, signal=20% | |
| 396 | REACTOME_METABOLISM_OF_WATER_SOLUBLE_VITAMINS_AND_COFACTORS | 23 | -0.27 | -0.67 | 0.900 | 0.957 | 1.000 | 2902 | tags=17%, list=13%, signal=20% | |
| 397 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | 10 | -0.33 | -0.66 | 0.872 | 0.965 | 1.000 | 4770 | tags=50%, list=22%, signal=64% | |
| 398 | REACTOME_BASE_EXCISION_REPAIR | 13 | -0.30 | -0.66 | 0.900 | 0.966 | 1.000 | 3987 | tags=31%, list=18%, signal=38% | |
| 399 | REACTOME_RESOLUTION_OF_ABASIC_SITES__AP_SITES_ | 13 | -0.30 | -0.65 | 0.919 | 0.965 | 1.000 | 3987 | tags=31%, list=18%, signal=38% | |
| 400 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA S ACS EPAC BRAF AND ERKCASCADE) | 198 | -0.19 | -0.64 | 1.000 | 0.969 | 1.000 | 2456 | tags=7%, list=11%, signal=8% | |
| 401 | INOH_HETEROTRIMERIC GPCR SIGNALING PATHWAY (THROUGH G ALPHA Q, PLC BETA AND ERK CASCADE) | 183 | -0.19 | -0.64 | 1.000 | 0.968 | 1.000 | 2193 | tags=6%, list=10%, signal=7% | |
| 402 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS II (VIA 24,25-DIHYDROLANOSTEROL) | 13 | -0.29 | -0.63 | 0.925 | 0.970 | 1.000 | 3067 | tags=23%, list=14%, signal=27% | |
| 403 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS III (VIA DESMOSTEROL) | 13 | -0.29 | -0.63 | 0.917 | 0.968 | 1.000 | 3067 | tags=23%, list=14%, signal=27% | |
| 404 | HUMANCYC_CHOLESTEROL BIOSYNTHESIS I | 13 | -0.29 | -0.62 | 0.921 | 0.970 | 1.000 | 3067 | tags=23%, list=14%, signal=27% | |
| 405 | INOH_NEGATIVE REGULATION OF (G ALPHA I GDP-GTP EXCHANGE SIGNALING) | 18 | -0.26 | -0.60 | 0.947 | 0.978 | 1.000 | 3570 | tags=22%, list=16%, signal=27% | |
| 406 | INOH_HETEROMERIC GPCR SIGNALING PATHWAY (THROUGH_G ALPHA S_ACS_PKA_BRAF_AND_ERKCASCADE)(CANONICAL) | 189 | -0.17 | -0.58 | 1.000 | 0.983 | 1.000 | 2232 | tags=6%, list=10%, signal=7% | |
| 407 | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PEROXISOME_PROLIFERATOR_ACTIVATED_RECEPTOR_ALPHA__PPARALPHA_ | 11 | -0.28 | -0.58 | 0.926 | 0.981 | 1.000 | 3602 | tags=18%, list=16%, signal=22% | |
| 408 | NCI_VISUAL SIGNAL TRANSDUCTION: RODS | 18 | -0.25 | -0.56 | 0.964 | 0.985 | 1.000 | 688 | tags=6%, list=3%, signal=6% | |
| 409 | REACTOME_STEROID_METABOLISM | 38 | -0.21 | -0.56 | 0.992 | 0.983 | 1.000 | 5955 | tags=37%, list=27%, signal=50% | |
| 410 | REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION | 14 | -0.23 | -0.52 | 0.965 | 0.990 | 1.000 | 3778 | tags=21%, list=17%, signal=26% | |
| 411 | REACTOME_CYTOCHROME_P450___ARRANGED_BY_SUBSTRATE_TYPE | 20 | -0.21 | -0.50 | 0.986 | 0.991 | 1.000 | 4642 | tags=20%, list=21%, signal=25% | |
| 412 | INOH_G ALPHA I GDP-GTP EXCHANGE SIGNALING | 35 | -0.14 | -0.37 | 1.000 | 0.999 | 1.000 | 4965 | tags=17%, list=23%, signal=22% |