Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | ATM_minus |
| GeneSet | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX |
| Enrichment Score (ES) | 0.7429367 |
| Normalized Enrichment Score (NES) | 1.8438988 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.023050603 |
| FWER p-Value | 0.183 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDK2 | 1416873_a_at 1447617_at | 8 | 5.536 | 0.3227 | Yes | ||
| 2 | POLA2 | 1425794_at 1448369_at 1456713_at | 629 | 1.509 | 0.3824 | Yes | ||
| 3 | MCM6 | 1416251_at 1438852_x_at 1447756_x_at | 679 | 1.462 | 0.4655 | Yes | ||
| 4 | MCM4 | 1416214_at 1436708_x_at | 761 | 1.378 | 0.5422 | Yes | ||
| 5 | POLE2 | 1427094_at 1431440_at | 1007 | 1.177 | 0.5997 | Yes | ||
| 6 | PRIM1 | 1418369_at 1444544_at 1449061_a_at | 1422 | 0.930 | 0.6351 | Yes | ||
| 7 | ORC5L | 1415830_at 1441601_at | 1672 | 0.832 | 0.6723 | Yes | ||
| 8 | ORC2L | 1418225_at 1418226_at 1418227_at | 1843 | 0.762 | 0.7090 | Yes | ||
| 9 | POLE | 1441854_at 1448650_a_at | 2009 | 0.711 | 0.7429 | Yes | ||
| 10 | CDC45L | 1416575_at 1457838_at | 2907 | 0.501 | 0.7313 | No | ||
| 11 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 4985 | 0.292 | 0.6535 | No | ||
| 12 | RPA1 | 1423293_at 1437309_a_at 1441240_at | 5735 | 0.245 | 0.6336 | No | ||
| 13 | RPA2 | 1416433_at 1454011_a_at | 9314 | 0.093 | 0.4758 | No | ||
| 14 | ORC4L | 1423336_at 1423337_at 1431172_at 1453804_a_at | 10870 | 0.041 | 0.4072 | No | ||
| 15 | POLA1 | 1419397_at 1456285_at 1459319_at 1459963_at | 11554 | 0.019 | 0.3771 | No | ||
| 16 | MCM3 | 1420029_at 1426653_at | 11978 | 0.004 | 0.3581 | No | ||
| 17 | CDC7 | 1426002_a_at 1426021_a_at | 12379 | -0.011 | 0.3404 | No | ||
| 18 | ORC1L | 1422663_at 1443172_at | 16631 | -0.211 | 0.1588 | No | ||
| 19 | MCM10 | 1433407_at 1433408_a_at 1454244_at | 17316 | -0.266 | 0.1431 | No | ||
| 20 | RPA3 | 1448938_at | 18042 | -0.345 | 0.1301 | No | ||
| 21 | MCM5 | 1415945_at 1436808_x_at | 18068 | -0.348 | 0.1493 | No | ||
| 22 | MCM2 | 1434079_s_at 1448777_at | 18785 | -0.465 | 0.1437 | No |
