Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | ATM_minus |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | 0.6826119 |
| Normalized Enrichment Score (NES) | 1.763733 |
| Nominal p-value | 0.0021645022 |
| FDR q-value | 0.040113665 |
| FWER p-Value | 0.486 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDK2 | 1416873_a_at 1447617_at | 8 | 5.536 | 0.2814 | Yes | ||
| 2 | CDC25A | 1417131_at 1417132_at 1445995_at | 47 | 3.621 | 0.4639 | Yes | ||
| 3 | MCM6 | 1416251_at 1438852_x_at 1447756_x_at | 679 | 1.462 | 0.5095 | Yes | ||
| 4 | MCM4 | 1416214_at 1436708_x_at | 761 | 1.378 | 0.5759 | Yes | ||
| 5 | ORC5L | 1415830_at 1441601_at | 1672 | 0.832 | 0.5768 | Yes | ||
| 6 | ORC2L | 1418225_at 1418226_at 1418227_at | 1843 | 0.762 | 0.6078 | Yes | ||
| 7 | RFC3 | 1423700_at 1432538_a_at | 1985 | 0.719 | 0.6379 | Yes | ||
| 8 | CDC25C | 1422252_a_at | 2391 | 0.607 | 0.6503 | Yes | ||
| 9 | RFC4 | 1424321_at 1438161_s_at | 2443 | 0.593 | 0.6782 | Yes | ||
| 10 | CDC45L | 1416575_at 1457838_at | 2907 | 0.501 | 0.6826 | Yes | ||
| 11 | CHEK1 | 1420031_at 1420032_at 1439208_at 1449708_s_at 1450677_at | 3820 | 0.380 | 0.6603 | No | ||
| 12 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 4985 | 0.292 | 0.6221 | No | ||
| 13 | RPA1 | 1423293_at 1437309_a_at 1441240_at | 5735 | 0.245 | 0.6003 | No | ||
| 14 | HUS1 | 1418308_at 1425366_a_at | 8853 | 0.110 | 0.4636 | No | ||
| 15 | RPA2 | 1416433_at 1454011_a_at | 9314 | 0.093 | 0.4474 | No | ||
| 16 | ORC4L | 1423336_at 1423337_at 1431172_at 1453804_a_at | 10870 | 0.041 | 0.3785 | No | ||
| 17 | MCM3 | 1420029_at 1426653_at | 11978 | 0.004 | 0.3282 | No | ||
| 18 | CDC7 | 1426002_a_at 1426021_a_at | 12379 | -0.011 | 0.3105 | No | ||
| 19 | RFC5 | 1452917_at | 14645 | -0.102 | 0.2122 | No | ||
| 20 | RAD9B | 1425800_at 1439955_at | 15104 | -0.121 | 0.1975 | No | ||
| 21 | RFC2 | 1417503_at 1457638_x_at 1457669_x_at | 15920 | -0.165 | 0.1687 | No | ||
| 22 | ORC1L | 1422663_at 1443172_at | 16631 | -0.211 | 0.1471 | No | ||
| 23 | MCM10 | 1433407_at 1433408_a_at 1454244_at | 17316 | -0.266 | 0.1294 | No | ||
| 24 | RPA3 | 1448938_at | 18042 | -0.345 | 0.1138 | No | ||
| 25 | MCM5 | 1415945_at 1436808_x_at | 18068 | -0.348 | 0.1304 | No | ||
| 26 | RAD1 | 1448414_at | 18652 | -0.439 | 0.1261 | No | ||
| 27 | MCM2 | 1434079_s_at 1448777_at | 18785 | -0.465 | 0.1437 | No |
