Details for gene set REGULATION_OF_SIGNAL

Table: GSEA Results Summary

Dataset	Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos
Phenotype	phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	REGULATION_OF_SIGNAL_TRANSDUCTION
Enrichment Score (ES)	-0.4984058
Normalized Enrichment Score (NES)	-1.6531311
Nominal p-value	0.0
FDR q-value	0.35784173
FWER p-Value	0.984

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	VAPA	1416465_a_at 1416466_at 1448349_at	203	2.343	0.0107	No
2	HMOX1	1448239_at	321	1.931	0.0217	No
3	UBE2N	1422559_at 1435384_at	522	1.575	0.0260	No
4	TGFB1	1420653_at 1445360_at	817	1.249	0.0231	No
5	ECM1	1448613_at	1084	1.067	0.0200	No
6	TFG	1415887_at 1438053_at	1095	1.062	0.0286	No
7	CITED2	1417129_a_at 1421267_a_at 1439915_at 1440091_at 1443561_at 1443926_at 1445638_at 1446176_at 1447861_x_at 1457632_s_at 1459301_at	1105	1.052	0.0372	No
8	PTPRC	1422124_a_at 1440165_at	1172	1.016	0.0428	No
9	BST2	1424921_at	1260	0.968	0.0471	No
10	CBLC	1422666_at 1431692_a_at	1333	0.927	0.0517	No
11	GNG7	1455190_at	1528	0.839	0.0499	No
12	ECT2	1419513_a_at	1545	0.832	0.0562	No
13	EEF1D	1428135_a_at 1439439_x_at 1449506_a_at 1459754_x_at	1763	0.746	0.0526	No
14	LGALS9	1421217_a_at	2026	0.660	0.0462	No
15	RPL17	1423855_x_at 1435791_x_at 1453752_at	2218	0.607	0.0426	No
16	GPR89A	1424696_at	2359	0.578	0.0411	No
17	GJA1	1415800_at 1415801_at 1437992_x_at 1438650_x_at 1438945_x_at 1438973_x_at	2449	0.557	0.0418	No
18	PPM1A	1415678_at 1417221_at 1425537_at 1429500_at 1429501_s_at 1443903_at 1451943_a_at 1453171_s_at	2476	0.550	0.0453	No
19	PLK2	1427005_at	2523	0.539	0.0478	No
20	RIC8B	1435096_at 1439724_at	2534	0.538	0.0519	No
21	CD24	1416034_at 1437502_x_at 1448182_a_at	2551	0.535	0.0557	No
22	ATP6AP2	1423662_at 1437688_x_at 1439456_x_at	2564	0.532	0.0597	No
23	GOLT1B	1449859_at 1460583_at	2593	0.525	0.0629	No
24	TNFRSF10B	1421296_at 1422344_s_at	2612	0.522	0.0665	No
25	MAPK8IP3	1416437_a_at 1425975_a_at 1436676_at 1460628_at	2765	0.489	0.0637	No
26	GRK1	1421361_at	2919	0.462	0.0606	No
27	TRAF3IP2	1445985_at 1448508_at	2977	0.453	0.0619	No
28	LTBR	1416435_at	3111	0.432	0.0594	No
29	LGALS1	1419573_a_at 1455439_a_at	3168	0.426	0.0605	No
30	SHC1	1422853_at 1422854_at	3459	0.392	0.0505	No
31	SMAD2	1420634_a_at 1458304_at	3526	0.385	0.0507	No
32	SOST	1421245_at 1436240_at 1450179_at	3714	0.363	0.0452	No
33	TSPAN6	1416872_at 1448501_at	3825	0.352	0.0432	No
34	GRM4	1457299_at	3855	0.349	0.0448	No
35	TPD52L1	1418412_at	3939	0.342	0.0439	No
36	TRIM13	1417888_at	4027	0.334	0.0428	No
37	GLI1	1449058_at	4186	0.321	0.0382	No
38	GRK4	1420355_at 1454152_a_at	4220	0.320	0.0395	No
39	RGS9	1418691_at 1426033_at 1439635_at	4245	0.318	0.0411	No
40	TDGF1	1450989_at	4494	0.301	0.0322	No
41	CASP8	1424552_at	4574	0.296	0.0311	No
42	ADRB3	1421555_at 1455918_at	4652	0.291	0.0301	No
43	ZDHHC17	1434397_at 1447656_at 1455986_at 1458084_at 1458363_at	4902	0.276	0.0210	No
44	PEG10	1427550_at	5051	0.267	0.0164	No
45	ABRA	1458455_at	5080	0.265	0.0174	No
46	NFAM1	1425714_a_at 1428790_at	5182	0.260	0.0150	No
47	NF1	1438067_at 1441523_at 1443097_at 1452525_a_at	5271	0.256	0.0131	No
48	CDKN1C	1417649_at	5595	0.239	0.0003	No
49	NEK6	1451043_at	6069	0.218	-0.0196	No
50	NCK2	1416796_at 1416797_at 1458432_at	6147	0.214	-0.0213	No
51	CIDEA	1417956_at	6634	0.195	-0.0420	No
52	RAC1	1423734_at 1437674_at 1451086_s_at	6772	0.190	-0.0467	No
53	RGS5	1420940_x_at 1420941_at	6935	0.185	-0.0526	No
54	FRZB	1416658_at 1448424_at	6975	0.183	-0.0528	No
55	NDFIP1	1424820_a_at 1424821_at 1451493_at	7047	0.181	-0.0545	No
56	PPP5C	1424115_at 1424116_x_at 1451242_a_at	7071	0.180	-0.0540	No
57	CDC42BPA	1435847_at 1436380_at 1438449_at 1442260_at 1446945_at	7303	0.172	-0.0632	No
58	IGF1	1419519_at 1436497_at 1437401_at 1452014_a_at	7365	0.169	-0.0646	No
59	LITAF	1416303_at 1416304_at	7383	0.169	-0.0639	No
60	RHOC	1435394_s_at 1448605_at	7414	0.168	-0.0638	No
61	PLEKHG5	1452248_at	7465	0.167	-0.0647	No
62	IL12A	1425454_a_at	7539	0.164	-0.0667	No
63	GRK5	1446361_at 1446998_at 1449514_at	7589	0.163	-0.0675	No
64	EREG	1419431_at	8099	0.145	-0.0897	No
65	ACVR2A	1437382_at 1439643_at 1445026_at 1451004_at	8150	0.143	-0.0908	No
66	TLR6	1421352_at	8519	0.133	-0.1066	No
67	NF2	1421820_a_at 1427708_a_at 1450382_at 1451829_a_at	8584	0.131	-0.1084	No
68	TMED4	1448422_at 1448423_at	8813	0.123	-0.1179	No
69	CASP1	1449265_at	9080	0.115	-0.1291	No
70	IL20	1421608_at	9287	0.109	-0.1377	No
71	MFN2	1441424_at 1448131_at 1451900_at	9543	0.101	-0.1485	No
72	AMBP	1416649_at	9577	0.100	-0.1492	No
73	SMAD3	1450471_at 1450472_s_at 1454960_at	9779	0.094	-0.1576	No
74	FGD5	1460578_at	10393	0.077	-0.1852	No
75	MAPK8IP2	1418785_at 1418786_at 1435045_s_at 1449225_a_at 1455194_at	10445	0.075	-0.1869	No
76	SECTM1	1419478_at 1419479_at	10461	0.075	-0.1869	No
77	TNFSF10	1420412_at 1439680_at 1459913_at	10505	0.074	-0.1883	No
78	RGN	1448852_at	10518	0.073	-0.1882	No
79	EGF	1418093_a_at	10553	0.072	-0.1891	No
80	EDA2R	1440085_at	10859	0.063	-0.2026	No
81	TGFA	1421942_s_at 1450421_at	10896	0.062	-0.2038	No
82	RIPK2	1421236_at 1450173_at	11268	0.052	-0.2204	No
83	ACVR2B	1419140_at 1439856_at	11514	0.045	-0.2313	No
84	EDG2	1417143_at 1426110_a_at 1448606_at	11551	0.044	-0.2326	No
85	ALS2	1417783_at 1417784_at 1431608_at 1446183_at	11636	0.041	-0.2361	No
86	FGD4	1425037_at 1426041_a_at 1426042_at 1451659_at 1455337_at	11686	0.040	-0.2380	No
87	CDH13	1423551_at 1431824_at 1454015_a_at 1459535_at	11817	0.036	-0.2437	No
88	PLCE1	1452398_at	11966	0.031	-0.2502	No
89	CANT1	1421476_a_at 1433709_at 1451688_s_at	12008	0.030	-0.2518	No
90	MYD88	1419272_at	12527	0.014	-0.2755	No
91	GIT1	1454759_at	12588	0.013	-0.2782	No
92	FGD2	1419515_at	13335	-0.012	-0.3124	No
93	ZIC1	1423477_at 1439627_at	13344	-0.012	-0.3127	No
94	OTUD7B	1428953_at 1429139_at 1435552_at 1457716_at	13548	-0.019	-0.3218	No
95	CDKN2B	1449152_at	13553	-0.019	-0.3219	No
96	OTX2	1425926_a_at	13997	-0.036	-0.3419	No
97	FASLG	1418803_a_at 1449235_at	14461	-0.054	-0.3628	No
98	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	14546	-0.057	-0.3662	No
99	CDC42BPB	1434652_at 1459167_at	14697	-0.063	-0.3725	No
100	MDFI	1420713_a_at 1425924_at	14882	-0.070	-0.3804	No
101	FGD6	1419322_at 1435467_at	15034	-0.077	-0.3867	No
102	TNFAIP3	1433699_at 1450829_at	15052	-0.078	-0.3868	No
103	ZDHHC13	1428307_at 1460048_at	15079	-0.079	-0.3873	No
104	HTR2B	1422125_at	15171	-0.085	-0.3908	No
105	RGS20	1421493_a_at 1443694_at 1446199_at	15395	-0.096	-0.4002	No
106	RGS11	1425245_a_at	15778	-0.114	-0.4168	No
107	SNX6	1425148_a_at 1429497_s_at 1447234_s_at 1451602_at	15814	-0.117	-0.4174	No
108	SLA2	1437504_at 1451492_at	15815	-0.117	-0.4164	No
109	MIB2	1424862_s_at	15840	-0.118	-0.4165	No
110	HGS	1416540_at	15845	-0.118	-0.4157	No
111	REL	1420710_at	16007	-0.128	-0.4220	No
112	DMPK	1422989_a_at 1434944_at	16010	-0.129	-0.4210	No
113	TRADD	1429117_at 1439910_a_at 1452622_a_at	16324	-0.150	-0.4341	No
114	RHOA	1437628_s_at	16372	-0.153	-0.4350	No
115	RASGRP4	1425380_at	16421	-0.157	-0.4358	No
116	RIPK1	1419508_at 1439273_at 1449485_at	16494	-0.162	-0.4377	No
117	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	16565	-0.168	-0.4395	No
118	MAPK8IP1	1425679_a_at 1440619_at	16574	-0.169	-0.4385	No
119	CXXC5	1431469_a_at 1448960_at	16705	-0.180	-0.4429	No
120	RGS16	1426037_a_at 1451452_a_at 1455265_a_at	16761	-0.184	-0.4439	No
121	HIPK2	1424863_a_at 1424864_at 1425983_x_at 1428433_at 1429566_a_at 1432523_at 1446167_at 1448631_a_at 1456022_at 1458520_at	17004	-0.207	-0.4532	No
122	CD40	1439221_s_at 1449473_s_at 1460415_a_at	17136	-0.221	-0.4574	No
123	SLC44A2	1428065_at 1438559_x_at 1438860_a_at	17396	-0.249	-0.4672	No
124	INHBA	1422053_at 1458291_at	17416	-0.252	-0.4659	No
125	FGD1	1416865_at 1437369_at 1459278_at	17723	-0.287	-0.4775	No
126	IL31RA	1445095_at 1451535_at	17911	-0.312	-0.4834	No
127	TRAF7	1424320_a_at	18034	-0.328	-0.4862	No
128	SNF1LK2	1444472_at 1457276_at	18097	-0.338	-0.4862	No
129	GNG4	1417943_at 1417944_at 1447669_s_at	18181	-0.350	-0.4871	No
130	SIGIRR	1449163_at	18196	-0.352	-0.4847	No
131	MALT1	1445068_at 1456126_at 1456429_at	18297	-0.366	-0.4862	No
132	THY1	1423135_at	18309	-0.368	-0.4835	No
133	TBK1	1422469_at 1445571_at 1460315_s_at	18339	-0.371	-0.4817	No
134	RALBP1	1417248_at 1448634_at	18424	-0.383	-0.4823	No
135	BRAP	1416738_at 1416739_a_at	18747	-0.444	-0.4933	No
136	ENG	1417271_a_at 1432176_a_at	18758	-0.447	-0.4900	No
137	CLCF1	1437270_a_at 1437271_at 1450262_at	18800	-0.456	-0.4880	No
138	MAP3K7IP2	1423462_at 1451003_at	18957	-0.490	-0.4910	No
139	TICAM1	1454676_s_at	19120	-0.525	-0.4939	Yes
140	SMURF1	1443393_at	19172	-0.538	-0.4917	Yes
141	TMEM9B	1417874_at 1448867_at	19177	-0.540	-0.4873	Yes
142	MDFIC	1427040_at	19282	-0.568	-0.4872	Yes
143	TSC1	1422043_at 1439989_at 1455252_at	19367	-0.587	-0.4860	Yes
144	TMEM101	1451315_at	19475	-0.613	-0.4857	Yes
145	RGS4	1416286_at 1416287_at 1448285_at	19529	-0.626	-0.4828	Yes
146	SCOTIN	1423986_a_at 1437503_a_at	19580	-0.640	-0.4797	Yes
147	NDFIP2	1452066_a_at	19587	-0.641	-0.4745	Yes
148	ARHGAP27	1416758_at 1457655_x_at	19637	-0.658	-0.4711	Yes
149	RELA	1419536_a_at	19723	-0.683	-0.4692	Yes
150	SLC35B2	1423927_at 1429007_at	19725	-0.684	-0.4634	Yes
151	CENTD2	1428064_at	19735	-0.687	-0.4580	Yes
152	CDC42BPG	1436197_at	19840	-0.721	-0.4566	Yes
153	RAMP1	1417481_at 1447474_at	19846	-0.724	-0.4506	Yes
154	F2R	1437308_s_at 1450852_s_at	19855	-0.727	-0.4448	Yes
155	HCLS1	1418842_at	19868	-0.733	-0.4391	Yes
156	SLC20A1	1438824_at 1446441_at 1448568_a_at	19943	-0.759	-0.4360	Yes
157	FADD	1416888_at 1446499_at	20011	-0.786	-0.4324	Yes
158	BIRC2	1418854_at	20095	-0.816	-0.4292	Yes
159	PTEN	1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at	20113	-0.822	-0.4230	Yes
160	GRK6	1437436_s_at 1450480_a_at 1451672_at	20236	-0.862	-0.4213	Yes
161	GPR177	1423824_at 1423825_at 1437434_a_at 1458319_at	20312	-0.897	-0.4171	Yes
162	MAP3K3	1426686_s_at 1426687_at 1436522_at	20318	-0.899	-0.4096	Yes
163	RGS3	1425701_a_at 1427648_at 1449516_a_at 1454026_a_at	20320	-0.900	-0.4020	Yes
164	NOTCH2	1451889_at 1455556_at	20365	-0.915	-0.3962	Yes
165	NUP62	1415925_a_at 1415926_at 1437612_at 1438917_x_at 1447905_x_at 1448150_at	20398	-0.933	-0.3897	Yes
166	ADRB2	1437302_at	20462	-0.963	-0.3844	Yes
167	ACVR1	1416786_at 1416787_at 1448460_at 1457551_at	20596	-1.046	-0.3816	Yes
168	FLNA	1426677_at	20659	-1.088	-0.3752	Yes
169	TRAT1	1427532_at 1437561_at	20681	-1.103	-0.3667	Yes
170	ARF6	1418822_a_at 1418823_at 1418824_at	20682	-1.104	-0.3573	Yes
171	TAX1BP3	1424169_at	20688	-1.108	-0.3481	Yes
172	ACVR1B	1422098_at 1433725_at	20742	-1.142	-0.3408	Yes
173	RGS2	1419247_at 1419248_at 1447830_s_at	20858	-1.223	-0.3356	Yes
174	IKBKE	1417813_at	20898	-1.262	-0.3266	Yes
175	FGD3	1433398_at 1450235_at 1454593_at	20975	-1.326	-0.3188	Yes
176	CC2D1A	1426422_at	20990	-1.342	-0.3080	Yes
177	TAOK3	1435964_a_at 1444366_at 1444881_at 1447257_at 1455733_at	21028	-1.394	-0.2978	Yes
178	RHOH	1429319_at 1441385_at 1443015_at	21077	-1.451	-0.2876	Yes
179	SOCS1	1440047_at 1450446_a_at	21129	-1.501	-0.2772	Yes
180	SQSTM1	1440076_at 1442237_at 1444021_at 1450957_a_at	21130	-1.503	-0.2643	Yes
181	CENTD3	1419833_s_at 1447407_at 1451282_at	21133	-1.505	-0.2516	Yes
182	RGS12	1429380_at 1453129_a_at 1457511_at 1459566_at	21134	-1.506	-0.2387	Yes
183	SMAD4	1422485_at 1422486_a_at 1422487_at 1444205_at	21192	-1.576	-0.2279	Yes
184	RGS14	1419221_a_at	21230	-1.635	-0.2157	Yes
185	CFLAR	1424996_at 1425686_at 1425687_at 1439600_at 1449317_at	21351	-1.795	-0.2059	Yes
186	TNFRSF1A	1417291_at	21427	-1.934	-0.1928	Yes
187	NLK	1419112_at 1435970_at 1443279_at 1445427_at 1456467_s_at	21448	-1.981	-0.1768	Yes
188	TAOK2	1438208_at 1443642_at 1456826_at	21488	-2.062	-0.1610	Yes
189	ATP2C1	1431196_at 1434386_at 1437738_at 1439215_at 1442742_at	21557	-2.215	-0.1453	Yes
190	EEF1E1	1444757_at 1449044_at	21736	-2.879	-0.1289	Yes
191	DTX1	1425822_a_at 1458643_at	21771	-3.048	-0.1044	Yes
192	GIT2	1423391_at 1432160_at 1435925_at	21792	-3.156	-0.0784	Yes
193	MIER1	1433755_at 1443400_at 1443879_at 1453760_at	21816	-3.301	-0.0513	Yes
194	FKBP1A	1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at	21931	-6.642	0.0001	Yes