DatasetSet_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls
#SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls
#SCID_versus_ATM_plus_repos
Phenotypephenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in classATM_plus
GeneSetBRCA1KO_MEF_DN
Enrichment Score (ES)-0.59635216
Normalized Enrichment Score (NES)-1.7546108
Nominal p-value0.0
FDR q-value0.1662565
FWER p-Value0.636
Table: GSEA Results Summary



Fig 1: Enrichment plot: BRCA1KO_MEF_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)
GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1ZFX1419565_a_at 1425972_a_at 1428046_a_at 1449512_a_at2622.4630.0380No
2MEF2C1421027_a_at 1421028_a_at 1424852_at 1439946_at 1445420_at 1446484_at 1451506_at 1451507_at 1458551_at3922.0640.0740No
3UTX1427235_at 1427672_a_at 1440524_at 1441201_at 1445198_at 1446234_at 1446278_at9471.1920.0728No
4FAF11418242_at 1434370_s_at21780.5840.0284No
5NET11421321_a_at 1457830_at22930.5560.0344No
6USP471426976_at 1426977_at 1457454_at24740.5130.0366No
7TGFBR31425620_at 1433795_at 1440041_at 1442332_at 1447314_at 1459355_at27240.4650.0346No
8FMR11423369_at 1426086_a_at 1452550_a_at31460.3950.0234No
9STK101417751_at 1459736_at33850.3660.0199No
10CDC2L61434997_at 1442225_at48640.259-0.0424No
11GFRA11421973_at 1439015_at 1450440_at49450.255-0.0409No
12NCOA11418594_a_at 1434515_at 1439883_at 1443397_at 1443438_at 1459277_at55940.227-0.0659No
13ROCK21423592_at 1451041_at56250.226-0.0627No
14DCLRE1A1417904_at 1432097_a_at 1442329_at65850.192-0.1027No
15ABCA11421839_at 1421840_at 1450392_at71990.173-0.1272No
16PDIA41416497_at76070.160-0.1426No
17UBE2L31417907_at 1417908_s_at 1448879_at 1448880_at82120.144-0.1673No
18RAI141417400_at 1417401_at 1441030_at 1444777_at94620.113-0.2222No
19CASP11449265_at97810.105-0.2346No
20CHD11420990_at 1444787_at 1444788_x_at 1450077_at 1457473_at107070.084-0.2752No
21BNIP31422470_at112060.072-0.2965No
22TJP11417749_a_at112300.072-0.2961No
23CCPG11420127_s_at 1424420_at 1447003_at118750.055-0.3245No
24HOXB91452317_at118950.055-0.3242No
25NEFL1426255_at131100.026-0.3792No
26VLDLR1417900_a_at 1434465_x_at 1435893_at 1438258_at 1442169_at 1451156_s_at133200.020-0.3884No
27ENPP21415894_at 1443224_at 1448136_at135570.014-0.3989No
28GOLGA41417674_s_at 1448803_at 1460213_at136200.012-0.4015No
29IPO71442511_at 1454955_at 1458165_at136850.010-0.4042No
30CASP41449591_at137840.008-0.4085No
31BAAT1419001_at 1419002_s_at140640.000-0.4213No
32NID11416808_at 1441519_at14319-0.008-0.4328No
33VPS351415783_at 1415784_at14593-0.017-0.4449No
34RFC11418342_at 1449050_at 1451920_a_at14628-0.018-0.4461No
35RABEP11421305_x_at 1426023_a_at 1427448_at 1443856_at 1444930_at 1459494_at14909-0.026-0.4584No
36CEBPZ1420497_a_at 1429962_at15621-0.053-0.4898No
37ZFR1419650_at 1442311_at 1443002_at 1443353_at 1443357_at 1444096_at 1449552_at 1458450_at16112-0.076-0.5107No
38TLOC11432635_a_at 1433704_s_at 1439233_at 1444811_at 1454697_at 1455698_at16391-0.091-0.5216No
39GSPT11426736_at 1426737_at 1435000_at 1446550_at 1452168_x_at 1455173_at16459-0.096-0.5227No
40GSTA41416368_at16843-0.121-0.5378No
41HFE1422645_at 1450702_at17099-0.142-0.5465No
42USP161430203_at 1431951_a_at17110-0.143-0.5441No
43SLK1419092_a_at 1425977_a_at 1433999_at 1441262_at 1443815_x_at 1449336_a_at17186-0.151-0.5445No
44SMARCA31425996_a_at 1450889_at 1451901_at17230-0.155-0.5433No
45UBE3A1416680_at 1416681_at 1416682_at 1425206_a_at 1431224_at 1445727_at17278-0.159-0.5422No
46ADD31423297_at 1423298_at 1426574_a_at 1447077_at 1456162_x_at17322-0.163-0.5409No
47COL3A11427883_a_at 1427884_at 1442977_at17798-0.212-0.5583No
48IMMT1429533_at 1429534_a_at 1433470_a_at 1437126_at17847-0.217-0.5561No
49ATF21426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at18187-0.264-0.5663No
50TPP21421893_a_at 1421894_a_at 1430575_a_at 1430576_at 1438264_a_at18846-0.364-0.5890Yes
51ITCH1415769_at 1431316_at 1459332_at18975-0.390-0.5869Yes
52NCOR11423200_at 1423201_at 1423202_a_at 1435914_at 1438276_at 1444760_at 1445230_at 1446574_at 1457007_at 1457938_at 1458103_at19001-0.395-0.5801Yes
53TOP11423474_at 1438495_at 1457573_at 1459672_at19100-0.415-0.5761Yes
54LAMC11423885_at 1423886_at19234-0.446-0.5732Yes
55PNN1423324_at 1423325_at19262-0.453-0.5652Yes
56NDRG31417663_a_at 1417664_a_at19354-0.475-0.5597Yes
57MAP2K41426233_at 1442679_at 1451982_at19388-0.482-0.5515Yes
58MGA1422646_at 1431232_a_at 1433012_at 1434746_at 1442356_at19443-0.494-0.5439Yes
59YME1L11423360_at 1423361_at 1437822_at 1450954_at19761-0.583-0.5466Yes
60GPT21434542_at 1438385_s_at 1439029_at 1455007_s_at19909-0.625-0.5406Yes
61XRN21422842_at 1450777_at20617-0.931-0.5541Yes
62SHOC21423129_at 1425845_a_at20729-1.016-0.5386Yes
63BAZ2B1435240_at 1440984_at 1441556_at 1442704_at 1442971_at 1445048_at 1448007_at 1458077_at20739-1.021-0.5183Yes
64MPO1415960_at20766-1.044-0.4983Yes
65ZNF1481418381_at 1427730_a_at 1436217_at 1441612_at 1441701_at 1449068_at 1449069_at 1455483_at20829-1.085-0.4791Yes
66EIF3S101416659_at 1416660_at 1416661_at 1448425_at20895-1.143-0.4589Yes
67KLF91422264_s_at 1428288_at 1428289_at 1436763_a_at 1436952_at 1452723_at 1456341_a_at21102-1.360-0.4408Yes
68ANGEL21415731_at 1431606_a_at 1437050_s_at 1448360_s_at 1453741_x_at 1455362_at21247-1.555-0.4158Yes
69CLK11426124_a_at21489-2.010-0.3860Yes
70SMAD11416081_at 1448208_at 1459843_s_at21506-2.046-0.3453Yes
71NFE2L21416543_at 1457117_at21541-2.121-0.3038Yes
72EPN21427225_at 1427226_at 1433915_s_at 1440175_at 1447599_x_at 1454303_at 1454304_at21558-2.168-0.2606Yes
73SEPP11452141_a_at21586-2.233-0.2165Yes
74NKTR1423248_at 1423249_at 1437660_at 1440804_at 1458676_at21610-2.316-0.1706Yes
75BIRC31421392_a_at 1425223_at21874-3.643-0.1087Yes
76TCF121421908_a_at 1427670_a_at 1438762_at 1439209_at 1439619_at 1443012_at 1444620_at 1445093_at 1445133_at 1457524_at 1458337_at21929-5.4960.0003Yes
Table: GSEA details [plain text format]



Fig 2: BRCA1KO_MEF_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: BRCA1KO_MEF_DN: Random ES distribution   
Gene set null distribution of ES for BRCA1KO_MEF_DN