Details for gene set REACTOME_REGULATION_OF_INSULIN

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	SCID
GeneSet	REACTOME_REGULATION_OF_INSULIN_SECRETION
Enrichment Score (ES)	0.6284655
Normalized Enrichment Score (NES)	1.9472786
Nominal p-value	0.0
FDR q-value	0.0022011697
FWER p-Value	0.01

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COX5B	1416902_a_at 1435613_x_at 1436149_at 1448514_at 1454716_x_at 1456588_x_at	1	6.901	0.0808	Yes
2	COX8A	1416112_at 1436409_at 1448222_x_at	7	6.333	0.1547	Yes
3	ATP5C1	1416058_s_at 1438809_at	29	4.740	0.2093	Yes
4	NDUFA10	1418068_at 1448934_at	51	4.175	0.2572	Yes
5	CYCS	1422484_at 1445484_at	164	3.037	0.2876	Yes
6	ATP5G1	1416020_a_at 1444874_at	227	2.644	0.3157	Yes
7	NDUFB2	1416834_x_at 1442658_at 1448483_a_at 1453806_at	328	2.212	0.3371	Yes
8	NDUFS8	1423907_a_at 1423908_at 1434212_at 1434213_x_at 1434579_x_at 1455283_x_at	337	2.196	0.3624	Yes
9	IQGAP1	1417379_at 1417380_at 1431395_a_at 1431396_at 1434998_at 1445724_at 1458124_at	363	2.129	0.3862	Yes
10	PDHA1	1418560_at 1446954_at 1449137_at	364	2.127	0.4111	Yes
11	GLP1R	1422330_at	508	1.810	0.4258	Yes
12	TPI1	1415918_a_at 1435659_a_at 1452927_x_at	818	1.314	0.4270	Yes
13	NDUFC1	1416285_at 1448284_a_at	847	1.273	0.4406	Yes
14	NDUFS7	1424313_a_at 1451312_at	864	1.252	0.4546	Yes
15	SDHD	1428235_at 1437489_x_at	1135	1.031	0.4543	Yes
16	NDUFS4	1418117_at 1438166_x_at 1444464_at 1448959_at 1459760_at	1166	1.014	0.4648	Yes
17	CS	1422577_at 1422578_at 1450667_a_at	1256	0.961	0.4720	Yes
18	CYC1	1416604_at	1259	0.960	0.4831	Yes
19	UQCR	1448292_at	1321	0.925	0.4911	Yes
20	ATP5E	1416567_s_at	1345	0.915	0.5008	Yes
21	SDHB	1418005_at	1446	0.863	0.5063	Yes
22	ATP5L	1448203_at	1485	0.846	0.5145	Yes
23	NDUFV1	1415966_a_at 1415967_at 1456015_x_at	1496	0.842	0.5239	Yes
24	ETFB	1428181_at	1611	0.788	0.5279	Yes
25	NDUFS6	1433603_at	1631	0.777	0.5361	Yes
26	NDUFA9	1416663_at	1706	0.737	0.5414	Yes
27	PKM2	1417308_at	1721	0.732	0.5493	Yes
28	SUCLG1	1415891_at	1817	0.699	0.5531	Yes
29	COX6C	1415970_at 1434491_a_at	1922	0.661	0.5561	Yes
30	NDUFA4	1424085_at	1943	0.654	0.5629	Yes
31	NDUFB10	1428322_a_at	2039	0.624	0.5658	Yes
32	NDUFV2	1428179_at 1438159_x_at 1452692_a_at	2112	0.603	0.5696	Yes
33	UQCRC1	1428782_a_at	2115	0.601	0.5765	Yes
34	NDUFB6	1434056_a_at 1434057_at	2181	0.583	0.5804	Yes
35	COX5A	1415933_a_at 1439267_x_at 1448153_at	2259	0.565	0.5835	Yes
36	NDUFB5	1417102_a_at 1448589_at	2285	0.558	0.5889	Yes
37	NDUFA8	1423692_at	2355	0.539	0.5920	Yes
38	ATP5O	1416278_a_at	2361	0.538	0.5981	Yes
39	ETFA	1423972_at	2367	0.537	0.6042	Yes
40	NDUFS1	1425143_a_at 1453354_at	2398	0.531	0.6090	Yes
41	IDH3G	1416788_a_at 1416789_at	2507	0.507	0.6100	Yes
42	ATP5F1	1426742_at 1433562_s_at	2558	0.497	0.6135	Yes
43	ATP5J2	1416269_at 1435395_s_at	2586	0.491	0.6180	Yes
44	IDH3B	1418885_a_at 1418886_s_at 1441271_at	2589	0.490	0.6237	Yes
45	NDUFA5	1417285_a_at 1417286_at	2632	0.483	0.6274	Yes
46	NDUFA6	1448427_at	2922	0.431	0.6192	Yes
47	PRKAR2B	1430640_a_at 1438664_at 1456475_s_at	3019	0.417	0.6197	Yes
48	ATP5J	1416143_at	3166	0.393	0.6176	Yes
49	NDUFS2	1451096_at	3223	0.385	0.6196	Yes
50	IDH3A	1422500_at 1422501_s_at 1432016_a_at 1447701_x_at	3224	0.385	0.6241	Yes
51	NDUFA7	1422976_x_at 1428360_x_at 1436567_a_at 1450818_a_at 1455749_x_at	3311	0.374	0.6245	Yes
52	ATP5B	1416829_at	3364	0.368	0.6264	Yes
53	ATP5I	1422525_at 1434053_x_at 1450640_x_at	3413	0.362	0.6285	Yes
54	NDUFA2	1417368_s_at	3685	0.334	0.6200	No
55	ATP5A1	1420037_at 1423111_at 1449710_s_at	3857	0.320	0.6159	No
56	NDUFS3	1423737_at	3907	0.316	0.6173	No
57	NDUFA1	1422241_a_at	3924	0.315	0.6203	No
58	NDUFB7	1416417_a_at 1448331_at	4053	0.304	0.6180	No
59	NDUFA3	1428464_at 1430149_at 1452790_x_at	4119	0.300	0.6185	No
60	KCNJ11	1450515_at 1455417_at	4190	0.295	0.6188	No
61	NDUFB3	1416547_at	4243	0.292	0.6198	No
62	UQCRQ	1427880_at 1430326_s_at 1437134_at 1452613_at	4254	0.292	0.6228	No
63	PFKFB1	1427213_at	4583	0.272	0.6109	No
64	SYT5	1422531_at	4807	0.262	0.6038	No
65	ATP5D	1423716_s_at 1456580_s_at	5080	0.249	0.5943	No
66	UQCRFS1	1450968_at	5182	0.245	0.5925	No
67	COX4I1	1448322_a_at	5260	0.241	0.5918	No
68	COX6B1	1416565_at 1436757_a_at	5469	0.232	0.5850	No
69	MDH2	1416478_a_at 1433984_a_at	5883	0.216	0.5686	No
70	ADRA2A	1423022_at 1433600_at 1433601_at	6211	0.204	0.5560	No
71	CHRM3	1422258_at	6409	0.198	0.5493	No
72	PDHB	1416090_at 1448214_at	6542	0.193	0.5455	No
73	PDHX	1456090_at 1459434_at	6901	0.181	0.5312	No
74	COX6A1	1417417_a_at	7695	0.157	0.4968	No
75	ABCC8	1455765_a_at 1457066_at	8577	0.135	0.4580	No
76	NDUFA11	1429708_at 1444154_at	8659	0.133	0.4558	No
77	UQCRC2	1428631_a_at 1435757_a_at	10607	0.086	0.3677	No
78	PFKFB3	1416432_at 1419882_at 1456676_a_at	10688	0.084	0.3650	No
79	NDUFC2	1431670_at	11217	0.072	0.3416	No
80	SDHA	1426688_at 1426689_s_at 1445317_at	11345	0.069	0.3366	No
81	AKAP5	1447301_at	11622	0.062	0.3247	No
82	GNAS	1421740_at 1427789_s_at 1443007_at 1443375_at 1444767_at 1450186_s_at 1453413_at	11887	0.055	0.3133	No
83	NDUFB4	1428075_at 1428076_s_at 1432427_at	12291	0.046	0.2954	No
84	UQCRH	1452133_at 1453229_s_at	12494	0.041	0.2866	No
85	GCG	1425952_a_at	13554	0.014	0.2382	No
86	ATP5H	1423676_at 1435112_a_at	13608	0.012	0.2360	No
87	NDUFS5	1416494_at 1416495_s_at	16242	-0.082	0.1163	No
88	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	16402	-0.092	0.1101	No
89	COX7C	1448112_at 1459884_at 1459885_s_at	16794	-0.118	0.0936	No
90	SLC2A2	1449067_at	17163	-0.149	0.0785	No
91	NDUFB8	1448198_a_at 1458404_at	17221	-0.154	0.0777	No
92	COX7A2L	1421772_a_at 1432263_a_at 1432264_x_at	17553	-0.185	0.0647	No
93	DLAT	1426264_at 1426265_x_at 1452005_at	18063	-0.247	0.0442	No
94	PFKFB4	1456888_at	18289	-0.280	0.0372	No
95	DLD	1423159_at	18621	-0.325	0.0259	No
96	MARCKS	1415971_at 1415972_at 1430311_at 1437034_x_at 1456028_x_at	19202	-0.439	0.0044	No
97	ETFDH	1451084_at 1458152_at	19266	-0.453	0.0069	No
98	PFKFB2	1422090_a_at 1422091_at 1422092_at 1429486_at 1431901_a_at	19623	-0.544	-0.0031	No
99	NDUFAB1	1428159_s_at 1428160_at 1435934_at 1447919_x_at 1453565_at 1458678_at	20293	-0.778	-0.0246	No
100	OGDH	1445632_at 1451274_at	20709	-1.001	-0.0319	No
101	DLST	1423710_at 1430161_at 1431011_at 1437775_at	21097	-1.353	-0.0338	No
102	RAP1A	1424139_at	21116	-1.376	-0.0185	No
103	VAMP2	1420833_at 1420834_at	21214	-1.515	-0.0052	No
104	PRKACB	1420610_at 1420611_at 1457197_at	21289	-1.608	0.0103	No
105	UQCRB	1416337_at 1455997_a_at	21322	-1.651	0.0281	No