Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos |
| Phenotype | phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | REACTOME_OPIOID_SIGNALLING |
| Enrichment Score (ES) | -0.67979515 |
| Normalized Enrichment Score (NES) | -1.623496 |
| Nominal p-value | 0.016129032 |
| FDR q-value | 0.20839821 |
| FWER p-Value | 0.969 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GNAI1 | 1427510_at 1434440_at 1454959_s_at | 1743 | 0.724 | -0.0270 | No | ||
| 2 | PRKAR2B | 1430640_a_at 1438664_at 1456475_s_at | 3019 | 0.417 | -0.0549 | No | ||
| 3 | GNAL | 1441654_at 1442021_at 1446359_at 1446491_at | 3565 | 0.344 | -0.0548 | No | ||
| 4 | PPP1CA | 1460165_at | 5703 | 0.223 | -0.1361 | No | ||
| 5 | OPRM1 | 1425432_at 1441791_at 1451705_a_at 1451709_at 1459402_at | 5896 | 0.216 | -0.1292 | No | ||
| 6 | GNA14 | 1420385_at 1447791_s_at 1449848_at 1458738_at | 10103 | 0.097 | -0.3141 | No | ||
| 7 | PRKACA | 1447720_x_at 1450519_a_at | 11849 | 0.056 | -0.3897 | No | ||
| 8 | PLA2G4A | 1448558_a_at | 12887 | 0.032 | -0.4346 | No | ||
| 9 | CDK5 | 1422590_at 1450674_at | 13760 | 0.008 | -0.4738 | No | ||
| 10 | GNAZ | 1426517_at 1435268_at | 14658 | -0.019 | -0.5134 | No | ||
| 11 | PDE4D | 1443289_at 1458212_at 1459289_at 1459311_at | 14809 | -0.023 | -0.5186 | No | ||
| 12 | CALM1 | 1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at | 15628 | -0.053 | -0.5520 | No | ||
| 13 | PDYN | 1416266_at | 16340 | -0.088 | -0.5781 | No | ||
| 14 | CREB1 | 1421582_a_at 1421583_at 1423402_at 1428755_at 1452529_a_at 1452901_at | 16598 | -0.105 | -0.5822 | No | ||
| 15 | ADRBK1 | 1426249_at 1451992_at | 18513 | -0.308 | -0.6472 | Yes | ||
| 16 | GNG2 | 1418451_at 1418452_at 1428156_at 1428157_at | 18983 | -0.392 | -0.6402 | Yes | ||
| 17 | PLCB2 | 1452481_at | 19419 | -0.489 | -0.6246 | Yes | ||
| 18 | ADCY6 | 1418128_at | 20630 | -0.938 | -0.6117 | Yes | ||
| 19 | GNB1 | 1417432_a_at 1425908_at 1454696_at 1459442_at | 20700 | -0.993 | -0.5428 | Yes | ||
| 20 | CAMK4 | 1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at | 21229 | -1.528 | -0.4560 | Yes | ||
| 21 | PRKACB | 1420610_at 1420611_at 1457197_at | 21289 | -1.608 | -0.3420 | Yes | ||
| 22 | PPP3R1 | 1421786_at 1433591_at 1450368_a_at | 21405 | -1.812 | -0.2158 | Yes | ||
| 23 | PDE4B | 1422473_at 1422474_at 1442700_at 1444731_at 1445449_at 1446577_at 1447237_at 1447718_at | 21826 | -3.306 | 0.0050 | Yes |
