Details for gene set REACTOME_DIABETES

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	SCID
GeneSet	REACTOME_DIABETES_PATHWAYS
Enrichment Score (ES)	0.5631264
Normalized Enrichment Score (NES)	1.8314945
Nominal p-value	0.0
FDR q-value	0.008487354
FWER p-Value	0.131

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COX5B	1416902_a_at 1435613_x_at 1436149_at 1448514_at 1454716_x_at 1456588_x_at	1	6.901	0.0586	Yes
2	RPL14	1422128_at 1426793_a_at 1433688_x_at 1436688_x_at 1438507_x_at 1438626_x_at	5	6.611	0.1147	Yes
3	COX8A	1416112_at 1436409_at 1448222_x_at	7	6.333	0.1685	Yes
4	DDOST	1416493_at 1420179_at	26	4.960	0.2099	Yes
5	ATP5C1	1416058_s_at 1438809_at	29	4.740	0.2501	Yes
6	NDUFA10	1418068_at 1448934_at	51	4.175	0.2847	Yes
7	EIF2S1	1440272_at 1452662_a_at	91	3.569	0.3132	Yes
8	CYCS	1422484_at 1445484_at	164	3.037	0.3357	Yes
9	ATP5G1	1416020_a_at 1444874_at	227	2.644	0.3554	Yes
10	NDUFS8	1423907_a_at 1423908_at 1434212_at 1434213_x_at 1434579_x_at 1455283_x_at	337	2.196	0.3691	Yes
11	IQGAP1	1417379_at 1417380_at 1431395_a_at 1431396_at 1434998_at 1445724_at 1458124_at	363	2.129	0.3860	Yes
12	PDHA1	1418560_at 1446954_at 1449137_at	364	2.127	0.4041	Yes
13	GLP1R	1422330_at	508	1.810	0.4129	Yes
14	NFYA	1422082_a_at 1427808_at 1452560_a_at	518	1.784	0.4277	Yes
15	RPS3	1435151_a_at 1447563_at 1455600_at	690	1.463	0.4323	Yes
16	TPI1	1415918_a_at 1435659_a_at 1452927_x_at	818	1.314	0.4376	Yes
17	NDUFC1	1416285_at 1448284_a_at	847	1.273	0.4472	Yes
18	NDUFS7	1424313_a_at 1451312_at	864	1.252	0.4571	Yes
19	SDHD	1428235_at 1437489_x_at	1135	1.031	0.4535	Yes
20	NDUFS4	1418117_at 1438166_x_at 1444464_at 1448959_at 1459760_at	1166	1.014	0.4607	Yes
21	CS	1422577_at 1422578_at 1450667_a_at	1256	0.961	0.4648	Yes
22	UQCR	1448292_at	1321	0.925	0.4697	Yes
23	ATP5E	1416567_s_at	1345	0.915	0.4764	Yes
24	SDHB	1418005_at	1446	0.863	0.4792	Yes
25	ATP5L	1448203_at	1485	0.846	0.4846	Yes
26	NDUFV1	1415966_a_at 1415967_at 1456015_x_at	1496	0.842	0.4913	Yes
27	ETFB	1428181_at	1611	0.788	0.4928	Yes
28	NDUFS6	1433603_at	1631	0.777	0.4985	Yes
29	NDUFA9	1416663_at	1706	0.737	0.5014	Yes
30	PKM2	1417308_at	1721	0.732	0.5070	Yes
31	SUCLG1	1415891_at	1817	0.699	0.5086	Yes
32	SSR2	1449930_a_at	1908	0.666	0.5101	Yes
33	COX6C	1415970_at 1434491_a_at	1922	0.661	0.5151	Yes
34	NDUFA4	1424085_at	1943	0.654	0.5198	Yes
35	NDUFB10	1428322_a_at	2039	0.624	0.5207	Yes
36	NDUFV2	1428179_at 1438159_x_at 1452692_a_at	2112	0.603	0.5226	Yes
37	UQCRC1	1428782_a_at	2115	0.601	0.5276	Yes
38	NDUFB6	1434056_a_at 1434057_at	2181	0.583	0.5295	Yes
39	NDUFB5	1417102_a_at 1448589_at	2285	0.558	0.5296	Yes
40	NDUFA8	1423692_at	2355	0.539	0.5310	Yes
41	ATP5O	1416278_a_at	2361	0.538	0.5353	Yes
42	SEC61B	1417083_at	2389	0.533	0.5386	Yes
43	RPS19	1449243_a_at 1460442_at	2419	0.526	0.5418	Yes
44	IDH3G	1416788_a_at 1416789_at	2507	0.507	0.5421	Yes
45	ATP5F1	1426742_at 1433562_s_at	2558	0.497	0.5440	Yes
46	ATP5J2	1416269_at 1435395_s_at	2586	0.491	0.5469	Yes
47	RPL18	1437005_a_at 1450372_a_at	2642	0.481	0.5485	Yes
48	RPL37	1453729_a_at	2657	0.478	0.5519	Yes
49	RPS4X	1416276_a_at	2868	0.440	0.5460	Yes
50	NDUFA6	1448427_at	2922	0.431	0.5473	Yes
51	PLA2G7	1430700_a_at	2997	0.421	0.5474	Yes
52	PRKAR2B	1430640_a_at 1438664_at 1456475_s_at	3019	0.417	0.5500	Yes
53	SEC61G	1423090_x_at	3070	0.407	0.5512	Yes
54	ATP5J	1416143_at	3166	0.393	0.5502	Yes
55	NDUFS2	1451096_at	3223	0.385	0.5509	Yes
56	IDH3A	1422500_at 1422501_s_at 1432016_a_at 1447701_x_at	3224	0.385	0.5541	Yes
57	NDUFA7	1422976_x_at 1428360_x_at 1436567_a_at 1450818_a_at 1455749_x_at	3311	0.374	0.5534	Yes
58	ATP5B	1416829_at	3364	0.368	0.5541	Yes
59	F2	1418897_at	3405	0.363	0.5554	Yes
60	ATP5I	1422525_at 1434053_x_at 1450640_x_at	3413	0.362	0.5581	Yes
61	RPS24	1436064_x_at 1436500_at 1453362_x_at 1455195_at 1456628_x_at	3597	0.342	0.5526	Yes
62	RPL8	1417762_a_at	3600	0.341	0.5554	Yes
63	RPL11	1417615_a_at	3654	0.336	0.5559	Yes
64	RPS3A	1422475_a_at	3660	0.336	0.5585	Yes
65	RPS25	1430978_at 1451068_s_at	3664	0.336	0.5612	Yes
66	NDUFA2	1417368_s_at	3685	0.334	0.5631	Yes
67	ATP5A1	1420037_at 1423111_at 1449710_s_at	3857	0.320	0.5580	No
68	IGFBP6	1417933_at	3906	0.317	0.5585	No
69	NDUFS3	1423737_at	3907	0.316	0.5612	No
70	RPSA	1416196_at 1448245_at	3972	0.311	0.5609	No
71	NDUFB7	1416417_a_at 1448331_at	4053	0.304	0.5598	No
72	KCNJ11	1450515_at 1455417_at	4190	0.295	0.5561	No
73	RPL6	1416546_a_at	4227	0.293	0.5569	No
74	NDUFB3	1416547_at	4243	0.292	0.5587	No
75	UQCRQ	1427880_at 1430326_s_at 1437134_at 1452613_at	4254	0.292	0.5607	No
76	PFKFB1	1427213_at	4583	0.272	0.5480	No
77	MMP2	1416136_at 1439364_a_at	4672	0.268	0.5462	No
78	RPS5	1416054_at	4680	0.267	0.5482	No
79	SYT5	1422531_at	4807	0.262	0.5446	No
80	ATP5D	1423716_s_at 1456580_s_at	5080	0.249	0.5342	No
81	UQCRFS1	1450968_at	5182	0.245	0.5317	No
82	RPS2	1431766_x_at	5241	0.242	0.5311	No
83	COX4I1	1448322_a_at	5260	0.241	0.5323	No
84	RPL4	1425183_a_at	5313	0.239	0.5319	No
85	COX6B1	1416565_at 1436757_a_at	5469	0.232	0.5268	No
86	RPS15A	1453467_s_at 1457726_at	5652	0.225	0.5204	No
87	MDH2	1416478_a_at 1433984_a_at	5883	0.216	0.5116	No
88	RPL41	1422623_x_at 1455578_x_at	5912	0.215	0.5122	No
89	ADRA2A	1423022_at 1433600_at 1433601_at	6211	0.204	0.5002	No
90	CHRM3	1422258_at	6409	0.198	0.4929	No
91	RPL28	1416074_a_at	6426	0.197	0.4938	No
92	SRP54	1430476_at 1441233_at 1441480_at	6479	0.196	0.4931	No
93	RPS23	1460175_at	7276	0.170	0.4580	No
94	COX6A1	1417417_a_at	7695	0.157	0.4401	No
95	RPL19	1416219_at	8258	0.143	0.4155	No
96	ABCC8	1455765_a_at 1457066_at	8577	0.135	0.4021	No
97	NDUFA11	1429708_at 1444154_at	8659	0.133	0.3995	No
98	RPLP2	1415879_a_at	9484	0.112	0.3626	No
99	RPL39	1423032_at 1450840_a_at	9661	0.108	0.3555	No
100	RPL18A	1428152_a_at	9994	0.100	0.3411	No
101	RPS20	1456373_x_at 1456436_x_at	10317	0.093	0.3271	No
102	ERN1	1421240_at 1431886_at 1437119_at 1438583_at 1438997_at 1450176_at	10367	0.091	0.3256	No
103	RPL17	1423855_x_at 1435791_x_at 1453752_at	10526	0.088	0.3191	No
104	UQCRC2	1428631_a_at 1435757_a_at	10607	0.086	0.3161	No
105	LEP	1422582_at	10875	0.079	0.3046	No
106	NDUFC2	1431670_at	11217	0.072	0.2895	No
107	KLK3	1450718_at 1453389_a_at	11293	0.070	0.2867	No
108	SDHA	1426688_at 1426689_s_at 1445317_at	11345	0.069	0.2849	No
109	IGF1	1419519_at 1436497_at 1437401_at 1452014_a_at	11555	0.064	0.2759	No
110	RPL37A	1416217_a_at 1460543_x_at	11638	0.062	0.2726	No
111	CPE	1415949_at	11815	0.057	0.2650	No
112	GNAS	1421740_at 1427789_s_at 1443007_at 1443375_at 1444767_at 1450186_s_at 1453413_at	11887	0.055	0.2622	No
113	NDUFB4	1428075_at 1428076_s_at 1432427_at	12291	0.046	0.2441	No
114	IGFALS	1422826_at	12688	0.037	0.2262	No
115	RPL27A	1437729_at	12816	0.034	0.2207	No
116	RPS28	1451101_a_at	13005	0.029	0.2123	No
117	NKX2-2	1421112_at	13361	0.019	0.1962	No
118	GCG	1425952_a_at	13554	0.014	0.1875	No
119	PCSK2	1428305_at 1444147_at 1447991_at 1447992_s_at 1448312_at	13858	0.006	0.1736	No
120	RPLP1	1416277_a_at	14633	-0.018	0.1382	No
121	ATF4	1438992_x_at 1439258_at 1448135_at	14825	-0.024	0.1297	No
122	SLC30A7	1450697_at	14954	-0.028	0.1240	No
123	IGFBP5	1422313_a_at 1452114_s_at	14975	-0.029	0.1233	No
124	IGFBP1	1418918_at	15444	-0.046	0.1023	No
125	SRP19	1450891_at	15636	-0.053	0.0939	No
126	FAU	1417452_a_at	15712	-0.057	0.0910	No
127	NDUFS5	1416494_at 1416495_s_at	16242	-0.082	0.0674	No
128	RPS14	1436586_x_at	16313	-0.086	0.0649	No
129	HSPA5	1416064_a_at 1427464_s_at 1447824_x_at	16347	-0.088	0.0641	No
130	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	16402	-0.092	0.0624	No
131	COX7C	1448112_at 1459884_at 1459885_s_at	16794	-0.118	0.0455	No
132	KLF4	1417394_at 1417395_at	17025	-0.136	0.0361	No
133	SLC2A2	1449067_at	17163	-0.149	0.0311	No
134	NDUFB8	1448198_a_at 1458404_at	17221	-0.154	0.0297	No
135	SPCS3	1451175_at	17810	-0.213	0.0046	No
136	SSR4	1427096_s_at 1435709_at 1448524_s_at	18114	-0.255	-0.0072	No
137	MBTPS1	1431385_a_at 1431386_s_at 1448240_at	18246	-0.273	-0.0109	No
138	PFKFB4	1456888_at	18289	-0.280	-0.0104	No
139	RPS21	1430288_x_at 1433549_x_at 1433721_x_at 1434358_x_at	18303	-0.282	-0.0086	No
140	ATF6	1435444_at 1453288_at 1456021_at	18349	-0.287	-0.0082	No
141	DLD	1423159_at	18621	-0.325	-0.0179	No
142	RPL5	1423665_a_at 1447460_at	18916	-0.377	-0.0282	No
143	SRP14	1418567_a_at 1418568_x_at 1454615_x_at 1455939_x_at	18948	-0.385	-0.0264	No
144	SRP72	1428876_at 1428877_at	19089	-0.414	-0.0293	No
145	ETFDH	1451084_at 1458152_at	19266	-0.453	-0.0335	No
146	SPCS2	1423215_at 1450907_at	19370	-0.478	-0.0342	No
147	PFKFB2	1422090_a_at 1422091_at 1422092_at 1429486_at 1431901_a_at	19623	-0.544	-0.0411	No
148	EXOC8	1436048_at	20237	-0.752	-0.0629	No
149	NDUFAB1	1428159_s_at 1428160_at 1435934_at 1447919_x_at 1453565_at 1458678_at	20293	-0.778	-0.0588	No
150	RPS16	1416404_s_at 1437196_x_at 1455835_at	20558	-0.895	-0.0633	No
151	OGDH	1445632_at 1451274_at	20709	-1.001	-0.0617	No
152	EXOC5	1436817_at 1438126_at	20812	-1.070	-0.0572	No
153	RAP1A	1424139_at	21116	-1.376	-0.0595	No
154	IGFBP4	1421991_a_at 1421992_a_at 1423756_s_at 1423757_x_at 1437405_a_at 1437406_x_at	21123	-1.380	-0.0480	No
155	VAMP2	1420833_at 1420834_at	21214	-1.515	-0.0392	No
156	UQCRB	1416337_at 1455997_a_at	21322	-1.651	-0.0301	No
157	KIF5B	1418427_at 1418428_at 1418429_at 1418430_at 1418431_at	21359	-1.708	-0.0172	No
158	RPS17	1437510_x_at 1438501_at 1438986_x_at 1455662_x_at 1457940_at 1459986_a_at	21924	-5.137	0.0006	No