Details for gene set NCI_ENDOTHELINS[GSEA]

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NCI_ENDOTHELINS
Enrichment Score (ES)	-0.51711214
Normalized Enrichment Score (NES)	-1.6529427
Nominal p-value	0.0
FDR q-value	0.1519344
FWER p-Value	0.92

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL5	1425546_a_at 1442049_at 1450550_at	130	3.232	0.0274	No
2	AKT1	1416657_at 1425711_a_at 1440950_at 1442759_at	182	2.933	0.0554	No
3	TBX21	1449361_at	242	2.572	0.0793	No
4	EIF4EBP1	1417562_at 1417563_at 1434976_x_at	583	1.660	0.0809	No
5	CALM3	1426710_at 1438825_at 1438826_x_at 1450864_at	1103	1.061	0.0680	No
6	CALM2	1422414_a_at 1423807_a_at	1171	1.010	0.0754	No
7	EIF4A1	1427058_at 1430980_a_at 1434985_a_at	1229	0.977	0.0828	No
8	COL1A2	1446326_at 1450857_a_at	1635	0.774	0.0723	No
9	CDK4	1422441_x_at	1669	0.757	0.0786	No
10	HRAS	1422407_s_at 1424132_at	1741	0.725	0.0828	No
11	GNAI1	1427510_at 1434440_at 1454959_s_at	1743	0.724	0.0902	No
12	PPP5C	1424115_at 1424116_x_at 1451242_a_at	1770	0.714	0.0964	No
13	SLC3A2	1425364_a_at	1947	0.653	0.0951	No
14	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	2079	0.612	0.0954	No
15	CASP3	1426165_a_at 1430192_at 1449839_at	2160	0.589	0.0978	No
16	EIF4G1	1427036_a_at 1427037_at 1438686_at	2273	0.561	0.0985	No
17	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	2363	0.538	0.1000	No
18	PPP2R5D	1450560_a_at	2644	0.481	0.0921	No
19	PIK3CA	1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at	2775	0.456	0.0908	No
20	MAPK1	1419568_at 1426585_s_at 1442876_at 1453104_at	3406	0.363	0.0657	No
21	ADCY1	1445112_at 1445359_at 1456487_at 1457251_x_at 1457329_at	3448	0.358	0.0675	No
22	GNAL	1441654_at 1442021_at 1446359_at 1446491_at	3565	0.344	0.0657	No
23	GNAO1	1421152_a_at 1448031_at 1460383_at	3759	0.328	0.0603	No
24	JAK2	1421065_at 1421066_at	3805	0.324	0.0615	No
25	FOSL1	1417487_at 1417488_at	3849	0.321	0.0629	No
26	PRKCE	1437860_at 1437861_s_at 1442609_at 1444649_at 1449956_at 1452878_at	4192	0.295	0.0502	No
27	PRKCZ	1418085_at 1449692_at 1454902_at	4536	0.274	0.0373	No
28	RPS6	1453466_at	4629	0.270	0.0359	No
29	PPARG	1420715_a_at	4732	0.265	0.0340	No
30	IL4	1449864_at	4912	0.257	0.0284	No
31	BAD	1416582_a_at 1416583_at	4939	0.255	0.0298	No
32	CSF2	1427429_at	5226	0.242	0.0192	No
33	RPS6KB1	1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at	5573	0.228	0.0057	No
34	TSC2	1452105_a_at	5821	0.219	-0.0034	No
35	MAF	1435828_at 1437473_at 1444073_at 1447849_s_at 1447945_at 1456060_at	5957	0.213	-0.0074	No
36	EIF4E	1450909_at 1457489_at 1459371_at	6477	0.196	-0.0292	No
37	FKBP8	1416113_at	6548	0.193	-0.0304	No
38	IL3	1450566_at	6633	0.190	-0.0323	No
39	EDNRB	1423594_a_at 1426314_at 1437347_at	6879	0.182	-0.0416	No
40	YWHAB	1420878_a_at 1420879_a_at 1420880_a_at 1436783_x_at 1438708_x_at 1455815_a_at	6981	0.179	-0.0444	No
41	MKNK1	1417630_at 1417631_at 1454119_at	7113	0.175	-0.0486	No
42	E2F1	1417878_at 1431875_a_at 1447840_x_at	7608	0.160	-0.0697	No
43	GNA12	1421026_at 1439206_at 1450096_at 1450097_s_at 1455008_at	7638	0.159	-0.0693	No
44	CYSLTR2	1421642_a_at	7850	0.153	-0.0774	No
45	EDN3	1421136_at 1438696_at 1441923_s_at 1441924_x_at	7899	0.152	-0.0781	No
46	TSC1	1422043_at 1439989_at 1455252_at	7907	0.151	-0.0768	No
47	ADCY9	1418586_at	8094	0.147	-0.0839	No
48	INSR	1421380_at 1450225_at	8400	0.139	-0.0964	No
49	EGF	1418093_a_at	8460	0.138	-0.0977	No
50	IFNG	1425947_at	8785	0.130	-0.1112	No
51	ADCY5	1439829_at 1443080_at 1447696_x_at 1455296_at	8813	0.129	-0.1111	No
52	IRS1	1423104_at	8941	0.126	-0.1157	No
53	GNA15	1421302_a_at	8945	0.126	-0.1145	No
54	IL2RA	1420691_at 1420692_at	9422	0.113	-0.1352	No
55	TNF	1419607_at	9455	0.113	-0.1355	No
56	EDN2	1449161_at	9515	0.112	-0.1370	No
57	ADCY8	1418754_at 1443704_at	10074	0.098	-0.1616	No
58	GNA14	1420385_at 1447791_s_at 1449848_at 1458738_at	10103	0.097	-0.1619	No
59	RAN	1443131_at 1446819_at 1447478_at 1460551_at	11162	0.073	-0.2097	No
60	ADCY4	1418098_at	11187	0.072	-0.2101	No
61	AKAP5	1447301_at	11622	0.062	-0.2294	No
62	PRKACA	1447720_x_at 1450519_a_at	11849	0.056	-0.2392	No
63	PTEN	1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at	12225	0.047	-0.2559	No
64	EGR4	1449977_at	12527	0.040	-0.2693	No
65	POU2F1	1419716_a_at 1427695_a_at 1427835_at	12594	0.039	-0.2719	No
66	PLA2G4A	1448558_a_at	12887	0.032	-0.2850	No
67	EGFR	1424932_at 1432647_at 1435888_at 1451530_at 1454313_at 1457563_at 1460420_a_at	13159	0.025	-0.2972	No
68	ADCY2	1455462_at	13283	0.021	-0.3026	No
69	NUP214	1434351_at 1456503_at 1457815_at	13511	0.015	-0.3129	No
70	BCAR1	1439388_s_at 1450622_at	13601	0.012	-0.3168	No
71	CYSLTR1	1418944_at 1449282_at	13901	0.004	-0.3305	No
72	RNF128	1418318_at 1449036_at	13942	0.003	-0.3323	No
73	PLCB1	1421170_a_at 1425600_a_at 1425781_a_at 1425782_at 1435043_at 1447004_at	14166	-0.003	-0.3425	No
74	EDNRA	1433525_at 1440093_at 1451691_at 1460513_a_at	14216	-0.005	-0.3447	No
75	PTPN1	1417068_a_at 1438670_at	14331	-0.008	-0.3499	No
76	JUN	1417409_at 1448694_at	14497	-0.014	-0.3573	No
77	FKBP1A	1416036_at 1438795_x_at 1438958_x_at 1448184_at 1456196_x_at	14549	-0.015	-0.3595	No
78	GNAZ	1426517_at 1435268_at	14658	-0.019	-0.3642	No
79	PTPRK	1423277_at 1423278_at 1431680_a_at 1441276_at 1441277_s_at 1441644_at 1443491_at 1443699_at 1444763_at	14713	-0.021	-0.3665	No
80	MAPK3	1427060_at	14783	-0.022	-0.3694	No
81	SRC	1423240_at 1450918_s_at	14992	-0.030	-0.3787	No
82	FOXP3	1420765_a_at 1457082_at	15403	-0.045	-0.3970	No
83	GNA11	1434254_at 1449144_at	15519	-0.049	-0.4018	No
84	CALM1	1417365_a_at 1417366_s_at 1433592_at 1454611_a_at 1455571_x_at	15628	-0.053	-0.4062	No
85	CRK	1416201_at 1425855_a_at 1436835_at 1448248_at 1460176_at	15694	-0.056	-0.4086	No
86	YWHAZ	1416102_at 1416103_at 1436971_x_at 1436981_a_at 1439005_x_at 1443893_at 1448218_s_at 1448219_a_at	15698	-0.056	-0.4082	No
87	PRKAB1	1424119_at 1452457_a_at	15803	-0.061	-0.4123	No
88	RAF1	1416078_s_at 1425419_a_at	15837	-0.063	-0.4132	No
89	TRPC6	1449431_at	15850	-0.064	-0.4131	No
90	FASLG	1418803_a_at 1449235_at	15860	-0.064	-0.4128	No
91	NFATC1	1417621_at 1425761_a_at 1428479_at 1447084_at 1447085_s_at	15972	-0.069	-0.4172	No
92	SLC9A3	1432771_at 1441236_at	16022	-0.072	-0.4187	No
93	XPO1	1418442_at 1418443_at 1448070_at	16219	-0.081	-0.4269	No
94	MAP2K1	1416351_at	16232	-0.082	-0.4266	No
95	ADCY3	1421959_s_at 1421960_at 1436928_s_at 1436929_x_at 1440405_at 1444641_at	16281	-0.084	-0.4279	No
96	NFATC2	1425901_at 1425990_a_at 1426031_a_at 1426032_at 1439205_at 1440426_at	16317	-0.086	-0.4286	No
97	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	16402	-0.092	-0.4315	No
98	SLC9A1	1417397_at	16705	-0.112	-0.4442	No
99	MAPK9	1421876_at 1421877_at 1421878_at	16802	-0.119	-0.4474	No
100	CD40LG	1422283_at	17003	-0.135	-0.4552	No
101	ADCY7	1420970_at 1450065_at 1456307_s_at	17324	-0.164	-0.4682	No
102	PRKCD	1422847_a_at 1442256_at	17365	-0.167	-0.4683	No
103	SFN	1448612_at	17471	-0.178	-0.4713	No
104	YWHAE	1426384_a_at 1426385_x_at 1435702_s_at 1438839_a_at 1440841_at 1457173_at	17505	-0.181	-0.4710	No
105	COL3A1	1427883_a_at 1427884_at 1442977_at	17798	-0.212	-0.4822	No
106	PRKCH	1422079_at 1434248_at	17855	-0.218	-0.4825	No
107	MAP3K8	1419208_at	18259	-0.276	-0.4981	No
108	RHEB	1416636_at	18445	-0.300	-0.5035	No
109	YWHAQ	1420828_s_at 1420829_a_at 1420830_x_at 1432842_s_at 1437608_x_at 1454378_at 1460590_s_at 1460621_x_at	18537	-0.311	-0.5045	No
110	CBLB	1437304_at 1455082_at 1458469_at	18786	-0.353	-0.5122	No
111	EDN1	1451924_a_at	18813	-0.357	-0.5097	No
112	ITCH	1415769_at 1431316_at 1459332_at	18975	-0.390	-0.5131	Yes
113	GRB2	1418508_a_at 1449111_a_at	18989	-0.393	-0.5096	Yes
114	YWHAH	1416004_at	19020	-0.399	-0.5069	Yes
115	GNAQ	1428938_at 1428939_s_at 1428940_at 1429559_at 1446688_at 1447593_x_at 1450115_at 1455729_at 1458159_at	19069	-0.409	-0.5048	Yes
116	IRF4	1421173_at 1421174_at	19146	-0.427	-0.5039	Yes
117	SOS1	1421884_at 1421885_at 1421886_at	19240	-0.448	-0.5036	Yes
118	KPNB1	1416925_at 1434357_a_at 1448526_at 1451967_x_at	19279	-0.456	-0.5006	Yes
119	PLCB2	1452481_at	19419	-0.489	-0.5019	Yes
120	CTLA4	1419334_at	19438	-0.493	-0.4976	Yes
121	MEF2D	1421388_at 1434487_at 1436642_x_at 1437300_at 1458901_at	19516	-0.517	-0.4958	Yes
122	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	19644	-0.549	-0.4960	Yes
123	CSNK1A1	1424827_a_at 1428537_at 1430529_at 1451497_at 1456216_at	19715	-0.569	-0.4933	Yes
124	GNAI3	1428645_at 1437225_x_at	19794	-0.592	-0.4908	Yes
125	YWHAG	1420816_at 1420817_at 1450012_x_at 1459693_x_at	19896	-0.621	-0.4890	Yes
126	PIM1	1423006_at 1435458_at	19899	-0.622	-0.4827	Yes
127	PTGS2	1417262_at 1417263_at	20129	-0.707	-0.4859	Yes
128	GNAI2	1419449_a_at 1435652_a_at	20160	-0.718	-0.4798	Yes
129	ADCY6	1418128_at	20630	-0.938	-0.4916	Yes
130	FOS	1423100_at	20795	-1.059	-0.4882	Yes
131	JUNB	1415899_at	20884	-1.130	-0.4806	Yes
132	BCL2	1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at	20911	-1.157	-0.4698	Yes
133	CSNK2A1	1419034_at 1419035_s_at 1419036_at 1419037_at 1419038_a_at 1453427_at	21003	-1.246	-0.4611	Yes
134	MAP3K1	1424850_at	21036	-1.286	-0.4493	Yes
135	EP300	1434765_at	21052	-1.301	-0.4365	Yes
136	GATA3	1448886_at	21135	-1.401	-0.4258	Yes
137	EEF2	1424736_at 1440784_at 1441414_at	21216	-1.518	-0.4138	Yes
138	CAMK4	1421941_at 1426167_a_at 1439843_at 1442822_at 1452572_at	21229	-1.528	-0.3986	Yes
139	FRAP1	1417592_at 1436267_a_at 1446185_at 1459625_at	21257	-1.565	-0.3836	Yes
140	PRKCQ	1426044_a_at	21352	-1.700	-0.3704	Yes
141	MAP2K2	1415974_at 1443436_at 1460636_at	21462	-1.936	-0.3554	Yes
142	PDPK1	1415729_at 1416501_at 1459775_at 1459776_x_at	21531	-2.098	-0.3368	Yes
143	NFATC3	1419976_s_at 1452497_a_at	21574	-2.204	-0.3159	Yes
144	DGKA	1418578_at	21651	-2.462	-0.2940	Yes
145	NR4A1	1416505_at	21728	-2.816	-0.2683	Yes
146	GSK3B	1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at	21817	-3.254	-0.2387	Yes
147	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	21856	-3.508	-0.2042	Yes
148	EGR2	1427682_a_at 1427683_at	21904	-4.293	-0.1620	Yes
149	EGR3	1421486_at 1436329_at	21908	-4.438	-0.1163	Yes
150	EGR1	1417065_at	21928	-5.313	-0.0622	Yes
151	PTK2B	1434653_at 1442437_at 1442927_at	21933	-6.050	0.0001	Yes