Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION |
| Enrichment Score (ES) | -0.6474221 |
| Normalized Enrichment Score (NES) | -1.5746474 |
| Nominal p-value | 0.009940358 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SOST | 1421245_at 1436240_at 1450179_at | 1619 | 0.577 | -0.0339 | No | ||
| 2 | ACVR1 | 1416786_at 1416787_at 1448460_at 1457551_at | 1966 | 0.480 | -0.0164 | No | ||
| 3 | THY1 | 1423135_at | 3381 | 0.259 | -0.0629 | No | ||
| 4 | CBLC | 1422666_at 1431692_a_at | 3778 | 0.227 | -0.0652 | No | ||
| 5 | ADRB3 | 1421555_at 1455918_at | 3788 | 0.226 | -0.0499 | No | ||
| 6 | SNX6 | 1425148_a_at 1429497_s_at 1447234_s_at 1451602_at | 3842 | 0.223 | -0.0369 | No | ||
| 7 | PEG10 | 1427550_at | 6009 | 0.121 | -0.1273 | No | ||
| 8 | NF2 | 1421820_a_at 1427708_a_at 1450382_at 1451829_a_at | 6347 | 0.111 | -0.1350 | No | ||
| 9 | FRZB | 1416658_at 1448424_at | 6724 | 0.099 | -0.1453 | No | ||
| 10 | AMBP | 1416649_at | 7522 | 0.078 | -0.1762 | No | ||
| 11 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 7628 | 0.076 | -0.1758 | No | ||
| 12 | MDFI | 1420713_a_at 1425924_at | 7878 | 0.070 | -0.1823 | No | ||
| 13 | CIDEA | 1417956_at | 9280 | 0.039 | -0.2435 | No | ||
| 14 | NF1 | 1438067_at 1441523_at 1443097_at 1452525_a_at | 10090 | 0.022 | -0.2790 | No | ||
| 15 | OTUD7B | 1428953_at 1429139_at 1435552_at 1457716_at | 10245 | 0.019 | -0.2847 | No | ||
| 16 | TSC1 | 1422043_at 1439989_at 1455252_at | 11052 | 0.003 | -0.3213 | No | ||
| 17 | MFN2 | 1441424_at 1448131_at 1451900_at | 11078 | 0.002 | -0.3222 | No | ||
| 18 | ADRB2 | 1437302_at | 12302 | -0.023 | -0.3765 | No | ||
| 19 | HGS | 1416540_at | 15477 | -0.102 | -0.5143 | No | ||
| 20 | PTPRC | 1422124_a_at 1440165_at | 16410 | -0.133 | -0.5476 | No | ||
| 21 | NLK | 1419112_at 1435970_at 1443279_at 1445427_at 1456467_s_at | 16818 | -0.149 | -0.5558 | No | ||
| 22 | SIGIRR | 1449163_at | 17961 | -0.212 | -0.5932 | No | ||
| 23 | TAOK3 | 1435964_a_at 1444366_at 1444881_at 1447257_at 1455733_at | 18775 | -0.281 | -0.6108 | No | ||
| 24 | BRAP | 1416738_at 1416739_a_at | 18818 | -0.285 | -0.5930 | No | ||
| 25 | SMURF1 | 1443393_at | 20011 | -0.472 | -0.6147 | Yes | ||
| 26 | TAX1BP3 | 1424169_at | 20257 | -0.541 | -0.5883 | Yes | ||
| 27 | SOCS1 | 1440047_at 1450446_a_at | 20707 | -0.704 | -0.5600 | Yes | ||
| 28 | SLA2 | 1437504_at 1451492_at | 20802 | -0.754 | -0.5120 | Yes | ||
| 29 | TNFAIP3 | 1433699_at 1450829_at | 21569 | -1.675 | -0.4307 | Yes | ||
| 30 | CENTD3 | 1419833_s_at 1447407_at 1451282_at | 21694 | -2.079 | -0.2921 | Yes | ||
| 31 | RHOH | 1429319_at 1441385_at 1443015_at | 21905 | -4.367 | 0.0014 | Yes |
