Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
Upregulated in class | SCID |
GeneSet | V$FOXO1_01 |
Enrichment Score (ES) | -0.49043563 |
Normalized Enrichment Score (NES) | -1.5404166 |
Nominal p-value | 0.0019455253 |
FDR q-value | 0.3805245 |
FWER p-Value | 0.772 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NDRG1 | 1423413_at 1450976_at 1456174_x_at | 148 | 2.520 | 0.0235 | No | ||
2 | ETV5 | 1420998_at 1428142_at 1450082_s_at | 263 | 2.018 | 0.0426 | No | ||
3 | SSBP3 | 1425940_a_at 1427917_s_at 1439136_at 1443554_at 1457560_at 1458749_at | 335 | 1.774 | 0.0607 | No | ||
4 | ELAVL2 | 1421881_a_at 1421882_a_at 1421883_at 1433052_at | 474 | 1.509 | 0.0725 | No | ||
5 | NR4A2 | 1447863_s_at 1450749_a_at 1450750_a_at 1455034_at | 491 | 1.465 | 0.0894 | No | ||
6 | LMO4 | 1420981_a_at 1439651_at | 518 | 1.409 | 0.1052 | No | ||
7 | NFIB | 1416293_at 1427680_a_at 1434101_at 1434102_at 1438072_at 1438244_at 1442214_at 1444800_at 1448288_at 1454834_at | 683 | 1.164 | 0.1116 | No | ||
8 | SLC38A2 | 1426722_at 1429593_at 1429594_at | 1202 | 0.741 | 0.0967 | No | ||
9 | CSNK1G3 | 1429383_at 1429384_at 1458994_at | 1260 | 0.709 | 0.1027 | No | ||
10 | BMI1 | 1417493_at 1448733_at | 1463 | 0.627 | 0.1009 | No | ||
11 | OSR1 | 1449350_at | 1596 | 0.584 | 0.1019 | No | ||
12 | UBL3 | 1423461_a_at | 1623 | 0.577 | 0.1076 | No | ||
13 | SFRS12 | 1427134_at 1427135_at 1427136_s_at 1458056_at | 1810 | 0.520 | 0.1053 | No | ||
14 | GFRA1 | 1421973_at 1439015_at 1450440_at | 1968 | 0.480 | 0.1039 | No | ||
15 | HSPB2 | 1429888_a_at | 2084 | 0.447 | 0.1040 | No | ||
16 | SMAD1 | 1416081_at 1448208_at 1459843_s_at | 2338 | 0.396 | 0.0971 | No | ||
17 | INHBA | 1422053_at 1458291_at | 2576 | 0.356 | 0.0905 | No | ||
18 | KLHDC2 | 1435086_s_at 1442596_at 1460678_at | 2713 | 0.336 | 0.0883 | No | ||
19 | JMJD1A | 1426810_at | 2885 | 0.314 | 0.0842 | No | ||
20 | BCL11B | 1440137_at 1441762_at 1450339_a_at | 2895 | 0.313 | 0.0876 | No | ||
21 | SLC26A2 | 1421145_at 1443882_at | 2971 | 0.303 | 0.0878 | No | ||
22 | SLITRK6 | 1437231_at | 3040 | 0.295 | 0.0882 | No | ||
23 | LPHN2 | 1434111_at 1434112_at 1444906_at | 3055 | 0.292 | 0.0911 | No | ||
24 | PURA | 1420628_at 1438219_at 1449934_at 1453783_at 1456898_at | 3117 | 0.285 | 0.0917 | No | ||
25 | HBP1 | 1432143_a_at 1438430_at 1446269_at 1460367_at | 3128 | 0.284 | 0.0947 | No | ||
26 | WBP4 | 1419374_at 1419375_at | 3157 | 0.281 | 0.0968 | No | ||
27 | CRB1 | 1421451_at 1441330_at | 3263 | 0.270 | 0.0952 | No | ||
28 | AXIN2 | 1421341_at 1436845_at | 3746 | 0.230 | 0.0758 | No | ||
29 | FSTL1 | 1416221_at 1448259_at | 3766 | 0.228 | 0.0777 | No | ||
30 | GPR110 | 1421443_at | 3839 | 0.223 | 0.0770 | No | ||
31 | MLL5 | 1427236_a_at 1432601_at 1434704_at 1439107_a_at 1439108_at | 3841 | 0.223 | 0.0797 | No | ||
32 | LAG3 | 1449911_at | 3850 | 0.222 | 0.0820 | No | ||
33 | YTHDF3 | 1426840_at 1426841_at 1426842_at 1445235_at | 3870 | 0.221 | 0.0838 | No | ||
34 | PALM | 1422034_a_at 1423967_at 1439927_at 1457217_at | 4110 | 0.204 | 0.0752 | No | ||
35 | PHACTR3 | 1429651_at | 4228 | 0.197 | 0.0722 | No | ||
36 | TRIM8 | 1418577_at 1427593_at 1438679_at 1460237_at | 4238 | 0.196 | 0.0742 | No | ||
37 | EZH1 | 1418290_a_at 1429629_at 1429630_at 1444604_at 1449023_a_at | 4380 | 0.188 | 0.0700 | No | ||
38 | NRG1 | 1456524_at | 4630 | 0.175 | 0.0606 | No | ||
39 | MGLL | 1426785_s_at 1431331_at 1450391_a_at 1453836_a_at | 4756 | 0.170 | 0.0569 | No | ||
40 | AP4M1 | 1418846_at | 4857 | 0.165 | 0.0543 | No | ||
41 | POU3F4 | 1422164_at 1422165_at | 5162 | 0.151 | 0.0421 | No | ||
42 | MITF | 1422025_at 1455214_at | 5203 | 0.150 | 0.0421 | No | ||
43 | ZFHX1B | 1422748_at 1434298_at 1442393_at 1445518_at 1454200_at 1456389_at | 5295 | 0.146 | 0.0397 | No | ||
44 | NMNAT2 | 1436155_at | 5314 | 0.145 | 0.0406 | No | ||
45 | SALL3 | 1441186_at 1452386_at | 5573 | 0.135 | 0.0304 | No | ||
46 | PLCB2 | 1452481_at | 5591 | 0.135 | 0.0312 | No | ||
47 | EPHB3 | 1451550_at | 5673 | 0.132 | 0.0291 | No | ||
48 | HHEX | 1423319_at | 5697 | 0.131 | 0.0296 | No | ||
49 | FST | 1421365_at 1434458_at | 5824 | 0.127 | 0.0253 | No | ||
50 | IRS4 | 1441429_at | 5847 | 0.126 | 0.0258 | No | ||
51 | NTRK3 | 1422329_a_at 1425070_at 1425071_s_at 1426003_at 1433825_at 1443970_at 1455917_at | 6060 | 0.119 | 0.0175 | No | ||
52 | KCNN1 | 1419617_at 1449536_at | 6192 | 0.115 | 0.0129 | No | ||
53 | NR2C2 | 1425014_at 1439696_at 1445613_at 1446955_at 1451569_at 1454167_at 1454851_at | 6435 | 0.108 | 0.0031 | No | ||
54 | TDRD5 | 1446208_at 1456391_at | 6611 | 0.103 | -0.0037 | No | ||
55 | NFIX | 1423493_a_at 1436363_a_at 1436364_x_at 1451443_at 1459909_at | 6837 | 0.096 | -0.0129 | No | ||
56 | PTPRD | 1424886_at 1429052_at 1435537_at 1439175_at 1440624_at 1441498_at 1441932_at 1442837_at 1443053_at 1443056_at 1443075_at 1443860_at 1444492_at 1444622_at 1445767_at 1459173_at | 6946 | 0.093 | -0.0168 | No | ||
57 | LHX1 | 1421951_at 1450428_at | 6987 | 0.092 | -0.0175 | No | ||
58 | A2BP1 | 1418314_a_at 1438217_at 1447735_x_at 1455358_at 1456921_at | 7029 | 0.091 | -0.0183 | No | ||
59 | SNCAIP | 1423499_at 1430463_a_at 1441037_at | 7373 | 0.082 | -0.0331 | No | ||
60 | IMPDH2 | 1415851_a_at 1415852_at | 7376 | 0.082 | -0.0322 | No | ||
61 | POU3F2 | 1450831_at 1453478_at 1457734_at | 7428 | 0.081 | -0.0335 | No | ||
62 | GRIK3 | 1427709_at | 7525 | 0.078 | -0.0370 | No | ||
63 | IGSF1 | 1433652_at 1438589_at 1447702_x_at | 7553 | 0.078 | -0.0373 | No | ||
64 | CADPS | 1444488_at 1445586_at 1448955_s_at 1458298_at | 7892 | 0.070 | -0.0520 | No | ||
65 | TBCC | 1424644_at 1451423_at | 8057 | 0.066 | -0.0588 | No | ||
66 | ABLIM3 | 1434013_at 1446069_at | 8123 | 0.065 | -0.0610 | No | ||
67 | AKT1S1 | 1428158_at 1437736_at 1452684_at | 8191 | 0.064 | -0.0633 | No | ||
68 | ARID4A | 1436191_at 1438464_at 1456420_at | 8365 | 0.059 | -0.0705 | No | ||
69 | GPR18 | 1439141_at | 8395 | 0.058 | -0.0712 | No | ||
70 | PROX1 | 1421336_at 1437894_at 1457432_at | 8878 | 0.047 | -0.0928 | No | ||
71 | SCRN3 | 1426916_at 1426917_s_at 1436573_at | 9497 | 0.034 | -0.1208 | No | ||
72 | C1QTNF3 | 1422606_at | 9752 | 0.028 | -0.1321 | No | ||
73 | NF1 | 1438067_at 1441523_at 1443097_at 1452525_a_at | 10090 | 0.022 | -0.1473 | No | ||
74 | SESN3 | 1449303_at 1453313_at | 10124 | 0.021 | -0.1486 | No | ||
75 | HOXA11 | 1420414_at | 10190 | 0.020 | -0.1513 | No | ||
76 | RASGEF1B | 1454742_at | 10488 | 0.014 | -0.1648 | No | ||
77 | EIF4EBP2 | 1417084_at 1436158_at 1437733_at 1455575_at 1456613_at | 10565 | 0.013 | -0.1681 | No | ||
78 | FGF9 | 1420795_at 1438718_at 1445258_at | 10941 | 0.005 | -0.1853 | No | ||
79 | BDNF | 1422168_a_at 1422169_a_at | 11002 | 0.004 | -0.1880 | No | ||
80 | TSC1 | 1422043_at 1439989_at 1455252_at | 11052 | 0.003 | -0.1903 | No | ||
81 | HIPK1 | 1421298_a_at 1424540_at 1457515_at | 11114 | 0.002 | -0.1930 | No | ||
82 | LHX5 | 1420348_at | 11121 | 0.001 | -0.1933 | No | ||
83 | CLDN2 | 1417231_at 1417232_at | 11509 | -0.007 | -0.2110 | No | ||
84 | HOXC4 | 1422870_at | 11549 | -0.008 | -0.2127 | No | ||
85 | ETV1 | 1422607_at 1445314_at 1450684_at | 11721 | -0.011 | -0.2204 | No | ||
86 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 11825 | -0.013 | -0.2250 | No | ||
87 | CREM | 1418322_at 1430598_at 1430847_a_at 1449037_at | 12080 | -0.019 | -0.2365 | No | ||
88 | ESRRG | 1421747_at 1455267_at 1457896_at | 12151 | -0.020 | -0.2394 | No | ||
89 | GPR109A | 1419721_at | 12476 | -0.027 | -0.2540 | No | ||
90 | SEMA6D | 1446536_at 1448060_at 1453055_at 1459318_at | 12499 | -0.027 | -0.2547 | No | ||
91 | EML1 | 1458317_at | 12504 | -0.028 | -0.2545 | No | ||
92 | SLC26A7 | 1425841_at | 12523 | -0.028 | -0.2550 | No | ||
93 | GRB7 | 1448227_at | 12539 | -0.029 | -0.2554 | No | ||
94 | BMF | 1422995_at 1454880_s_at 1458325_x_at | 12552 | -0.029 | -0.2556 | No | ||
95 | SOX2 | 1416967_at | 12580 | -0.029 | -0.2565 | No | ||
96 | KLF12 | 1439846_at 1439847_s_at 1441040_at 1455521_at | 12734 | -0.033 | -0.2631 | No | ||
97 | PITX2 | 1424797_a_at 1450482_a_at | 12774 | -0.034 | -0.2645 | No | ||
98 | DDIT4 | 1428306_at | 12966 | -0.038 | -0.2728 | No | ||
99 | GTF2B | 1438066_at 1451135_at | 13112 | -0.042 | -0.2790 | No | ||
100 | PAPPA | 1427633_a_at 1432591_at 1432592_at 1459375_at | 13177 | -0.043 | -0.2814 | No | ||
101 | LASP1 | 1438633_x_at 1438634_x_at 1439264_x_at 1444947_at 1448207_at 1455470_x_at 1456309_x_at 1456469_x_at 1456578_x_at 1460173_at | 13275 | -0.045 | -0.2853 | No | ||
102 | DTNA | 1419223_a_at 1425292_at 1426066_a_at 1427588_a_at 1429768_at 1447280_at 1456069_at 1458908_at | 13298 | -0.045 | -0.2858 | No | ||
103 | APOA2 | 1417950_a_at | 13334 | -0.046 | -0.2868 | No | ||
104 | TBX4 | 1426321_at 1456033_at | 13541 | -0.051 | -0.2957 | No | ||
105 | WHSC1L1 | 1442085_at 1447931_at 1455668_at 1457630_at 1457793_a_at 1457794_at 1459907_a_at | 13574 | -0.051 | -0.2965 | No | ||
106 | NKX2-2 | 1421112_at | 13837 | -0.058 | -0.3079 | No | ||
107 | CCND1 | 1417419_at 1417420_at 1448698_at | 14109 | -0.065 | -0.3196 | No | ||
108 | HESX1 | 1420604_at | 14151 | -0.066 | -0.3206 | No | ||
109 | H2AFX | 1416746_at | 14194 | -0.067 | -0.3218 | No | ||
110 | GATA6 | 1425463_at 1425464_at 1443081_at | 14454 | -0.074 | -0.3328 | No | ||
111 | SDK2 | 1430425_at 1457333_at | 14463 | -0.074 | -0.3323 | No | ||
112 | CRH | 1457984_at | 14488 | -0.075 | -0.3325 | No | ||
113 | EFEMP1 | 1427183_at | 14529 | -0.076 | -0.3334 | No | ||
114 | KBTBD5 | 1431043_at | 14535 | -0.076 | -0.3327 | No | ||
115 | CSAD | 1427981_a_at | 14702 | -0.081 | -0.3394 | No | ||
116 | CDKN1C | 1417649_at | 14808 | -0.084 | -0.3432 | No | ||
117 | BIN1 | 1423618_at 1425532_a_at 1444120_at | 15025 | -0.089 | -0.3520 | No | ||
118 | EPHB1 | 1455188_at | 15110 | -0.092 | -0.3548 | No | ||
119 | ASB7 | 1435010_at 1438744_at 1446319_at 1450363_at | 15158 | -0.093 | -0.3558 | No | ||
120 | ZADH2 | 1451277_at | 15501 | -0.103 | -0.3703 | No | ||
121 | FGF14 | 1435747_at 1447221_x_at 1447480_at 1449958_a_at 1458830_at 1459073_x_at | 15505 | -0.103 | -0.3692 | No | ||
122 | PRDM1 | 1420425_at 1444997_at | 15531 | -0.104 | -0.3691 | No | ||
123 | SLITRK5 | 1429718_at | 15602 | -0.106 | -0.3711 | No | ||
124 | DUSP1 | 1448830_at | 15775 | -0.112 | -0.3776 | No | ||
125 | LRRC1 | 1452411_at | 15828 | -0.114 | -0.3786 | No | ||
126 | DEPDC2 | 1432047_at | 15843 | -0.114 | -0.3779 | No | ||
127 | ELOVL6 | 1417403_at 1417404_at 1445062_at 1445578_at 1445641_at | 15858 | -0.115 | -0.3772 | No | ||
128 | LMO3 | 1455754_at | 15878 | -0.115 | -0.3767 | No | ||
129 | SH3BP5 | 1421922_at 1421923_at 1444346_at | 15965 | -0.118 | -0.3792 | No | ||
130 | HOXB8 | 1452493_s_at | 16753 | -0.146 | -0.4136 | No | ||
131 | FGF12 | 1440270_at 1451693_a_at 1460137_at | 16899 | -0.152 | -0.4184 | No | ||
132 | HOXB4 | 1451761_at 1460379_at | 16918 | -0.152 | -0.4174 | No | ||
133 | PMCH | 1429361_at | 16940 | -0.153 | -0.4166 | No | ||
134 | GPR63 | 1422338_at 1440725_at | 17013 | -0.157 | -0.4180 | No | ||
135 | CXXC5 | 1431469_a_at 1448960_at | 17047 | -0.158 | -0.4176 | No | ||
136 | PDCD4 | 1444171_at | 17064 | -0.159 | -0.4164 | No | ||
137 | SEMA4G | 1449202_at | 17221 | -0.166 | -0.4216 | No | ||
138 | GPRC5C | 1424450_at 1452947_at | 17322 | -0.172 | -0.4241 | No | ||
139 | SYT6 | 1420188_at 1426106_a_at 1449766_at 1449767_x_at | 17609 | -0.189 | -0.4350 | No | ||
140 | PLXDC2 | 1418912_at 1449270_at | 17612 | -0.189 | -0.4328 | No | ||
141 | THRA | 1426997_at 1443952_at 1454675_at | 17956 | -0.212 | -0.4460 | No | ||
142 | FOXP2 | 1422014_at 1438231_at 1438232_at 1440108_at 1441365_at 1458191_at | 18070 | -0.220 | -0.4486 | No | ||
143 | CHES1 | 1434002_at 1436925_at 1438255_at 1440607_at 1444555_at 1447325_at 1453094_at | 18085 | -0.221 | -0.4466 | No | ||
144 | TBC1D17 | 1423659_a_at | 18233 | -0.232 | -0.4505 | No | ||
145 | IL1RAPL1 | 1445821_at 1458964_at | 18289 | -0.235 | -0.4502 | No | ||
146 | DEDD | 1432000_a_at 1434994_at 1434995_s_at | 18564 | -0.261 | -0.4597 | No | ||
147 | ORC1L | 1422663_at 1443172_at | 18790 | -0.283 | -0.4666 | No | ||
148 | TAZ | 1416207_at 1453785_at | 18828 | -0.286 | -0.4649 | No | ||
149 | HOXA3 | 1427433_s_at 1441070_at 1452421_at | 19039 | -0.309 | -0.4708 | No | ||
150 | CNNM3 | 1420480_at 1420481_at 1420482_at 1420483_at 1441544_at 1458330_x_at | 19138 | -0.322 | -0.4714 | No | ||
151 | OPA3 | 1455131_at | 19406 | -0.361 | -0.4794 | No | ||
152 | SLC25A28 | 1424776_a_at | 19407 | -0.361 | -0.4750 | No | ||
153 | KCNJ15 | 1435354_at 1443054_at 1450185_a_at | 19468 | -0.370 | -0.4733 | No | ||
154 | H3F3B | 1420376_a_at 1430357_at 1455725_a_at | 19573 | -0.386 | -0.4735 | No | ||
155 | MED8 | 1431423_a_at 1442417_at | 19603 | -0.391 | -0.4701 | No | ||
156 | ANKRD28 | 1434630_at 1454801_at | 19928 | -0.452 | -0.4796 | No | ||
157 | RUNX1 | 1422864_at 1422865_at 1427650_a_at 1427847_at 1440878_at 1444527_at 1446930_at 1452530_a_at 1452531_at 1452578_at 1459470_at | 19942 | -0.456 | -0.4747 | No | ||
158 | DDX17 | 1437773_x_at 1439037_at 1452155_a_at | 20045 | -0.481 | -0.4736 | No | ||
159 | SH3GL3 | 1432103_a_at | 20413 | -0.583 | -0.4834 | Yes | ||
160 | ITPR3 | 1417297_at | 20439 | -0.595 | -0.4774 | Yes | ||
161 | USP3 | 1425022_at 1425023_at 1435531_at 1441056_at 1446886_at | 20549 | -0.631 | -0.4748 | Yes | ||
162 | ZFYVE1 | 1435071_at 1435072_at | 20575 | -0.641 | -0.4683 | Yes | ||
163 | CHCHD7 | 1440158_x_at 1444318_at 1446844_at 1454640_at | 20620 | -0.661 | -0.4623 | Yes | ||
164 | CCNG2 | 1416488_at 1448364_at | 20726 | -0.715 | -0.4585 | Yes | ||
165 | LCP2 | 1418641_at 1418642_at | 20805 | -0.755 | -0.4530 | Yes | ||
166 | CHD1 | 1420990_at 1444787_at 1444788_x_at 1450077_at 1457473_at | 20911 | -0.827 | -0.4479 | Yes | ||
167 | PLAG1 | 1421745_at 1443943_at | 20954 | -0.857 | -0.4395 | Yes | ||
168 | ATF7IP | 1446323_at 1449192_at 1454973_at 1459096_at | 21124 | -1.003 | -0.4352 | Yes | ||
169 | SPAG9 | 1430556_at 1433648_at 1437676_at | 21256 | -1.139 | -0.4275 | Yes | ||
170 | UTX | 1427235_at 1427672_a_at 1440524_at 1441201_at 1445198_at 1446234_at 1446278_at | 21341 | -1.267 | -0.4161 | Yes | ||
171 | DLX1 | 1449470_at | 21371 | -1.298 | -0.4018 | Yes | ||
172 | UBE2H | 1418631_at 1418632_at 1428791_at 1438971_x_at 1447374_at 1459930_at | 21478 | -1.495 | -0.3887 | Yes | ||
173 | ASXL1 | 1434561_at 1435077_at 1458380_at | 21529 | -1.599 | -0.3718 | Yes | ||
174 | PPP1CB | 1426205_at 1431328_at 1433540_x_at 1456462_x_at | 21533 | -1.605 | -0.3526 | Yes | ||
175 | NFYA | 1422082_a_at 1427808_at 1452560_a_at | 21556 | -1.641 | -0.3338 | Yes | ||
176 | EMP1 | 1416529_at 1459171_at | 21618 | -1.820 | -0.3147 | Yes | ||
177 | EXT1 | 1417730_at 1439877_at 1440011_at 1440092_at 1456655_at 1458054_at 1458296_at | 21631 | -1.845 | -0.2931 | Yes | ||
178 | DMD | 1417307_at 1430320_at 1446156_at 1448665_at 1457022_at | 21702 | -2.099 | -0.2710 | Yes | ||
179 | FOXO1A | 1416981_at 1416982_at 1416983_s_at 1459170_at | 21749 | -2.340 | -0.2450 | Yes | ||
180 | OLIG3 | 1421728_at | 21795 | -2.639 | -0.2153 | Yes | ||
181 | NNT | 1416105_at 1432608_at 1456573_x_at | 21803 | -2.678 | -0.1834 | Yes | ||
182 | BUB3 | 1416815_s_at 1448058_s_at 1448473_at 1459104_at 1459918_at | 21917 | -5.037 | -0.1280 | Yes | ||
183 | CYR61 | 1416039_x_at 1417848_at 1417849_at 1438133_a_at 1442340_x_at 1457823_at 1459462_at | 21924 | -5.210 | -0.0655 | Yes | ||
184 | H2AFV | 1428029_a_at 1436596_at | 21928 | -5.485 | 0.0004 | Yes |