Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | REACTOME_L13A_MEDIATED_TRANSLATIONAL_SILENCING_OF_CERULOPLASMIN_EXPRESSION |
| Enrichment Score (ES) | -0.63367534 |
| Normalized Enrichment Score (NES) | -1.6743178 |
| Nominal p-value | 0.008080808 |
| FDR q-value | 0.4156149 |
| FWER p-Value | 0.905 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | EIF2S2 | 1417712_at 1417713_at 1441023_at 1448819_at 1448820_a_at 1456617_a_at | 281 | 1.952 | 0.0667 | No | ||
| 2 | RPL30 | 1438076_at 1456266_at | 420 | 1.618 | 0.1262 | No | ||
| 3 | RPL4 | 1425183_a_at | 2122 | 0.439 | 0.0664 | No | ||
| 4 | RPS3A | 1422475_a_at | 2915 | 0.310 | 0.0429 | No | ||
| 5 | RPL27A | 1437729_at | 2967 | 0.304 | 0.0529 | No | ||
| 6 | RPS3 | 1435151_a_at 1447563_at 1455600_at | 3632 | 0.238 | 0.0322 | No | ||
| 7 | EIF2S1 | 1440272_at 1452662_a_at | 4119 | 0.204 | 0.0183 | No | ||
| 8 | EIF4G1 | 1427036_a_at 1427037_at 1438686_at | 4282 | 0.193 | 0.0188 | No | ||
| 9 | RPL18 | 1437005_a_at 1450372_a_at | 5066 | 0.155 | -0.0106 | No | ||
| 10 | RPS24 | 1436064_x_at 1436500_at 1453362_x_at 1455195_at 1456628_x_at | 5158 | 0.151 | -0.0086 | No | ||
| 11 | RPS21 | 1430288_x_at 1433549_x_at 1433721_x_at 1434358_x_at | 5877 | 0.125 | -0.0364 | No | ||
| 12 | RPS14 | 1436586_x_at | 6345 | 0.111 | -0.0532 | No | ||
| 13 | RPS23 | 1460175_at | 6930 | 0.094 | -0.0760 | No | ||
| 14 | RPS28 | 1451101_a_at | 8388 | 0.059 | -0.1402 | No | ||
| 15 | RPS11 | 1424000_a_at | 9553 | 0.033 | -0.1921 | No | ||
| 16 | RPL37A | 1416217_a_at 1460543_x_at | 9936 | 0.025 | -0.2085 | No | ||
| 17 | RPL8 | 1417762_a_at | 10152 | 0.021 | -0.2175 | No | ||
| 18 | RPL6 | 1416546_a_at | 10328 | 0.017 | -0.2248 | No | ||
| 19 | RPS2 | 1431766_x_at | 10619 | 0.012 | -0.2375 | No | ||
| 20 | RPL41 | 1422623_x_at 1455578_x_at | 10938 | 0.005 | -0.2518 | No | ||
| 21 | RPS25 | 1430978_at 1451068_s_at | 10979 | 0.004 | -0.2535 | No | ||
| 22 | EIF4A1 | 1427058_at 1430980_a_at 1434985_a_at | 11569 | -0.008 | -0.2801 | No | ||
| 23 | RPL18A | 1428152_a_at | 11989 | -0.017 | -0.2985 | No | ||
| 24 | FAU | 1417452_a_at | 12027 | -0.018 | -0.2995 | No | ||
| 25 | RPLP1 | 1416277_a_at | 12236 | -0.022 | -0.3081 | No | ||
| 26 | RPL11 | 1417615_a_at | 12796 | -0.034 | -0.3322 | No | ||
| 27 | RPSA | 1416196_at 1448245_at | 12918 | -0.037 | -0.3362 | No | ||
| 28 | RPS20 | 1456373_x_at 1456436_x_at | 13098 | -0.041 | -0.3427 | No | ||
| 29 | RPL28 | 1416074_a_at | 13562 | -0.051 | -0.3618 | No | ||
| 30 | RPL39 | 1423032_at 1450840_a_at | 13626 | -0.053 | -0.3625 | No | ||
| 31 | RPS5 | 1416054_at | 13721 | -0.055 | -0.3646 | No | ||
| 32 | RPS19 | 1449243_a_at 1460442_at | 14222 | -0.068 | -0.3847 | No | ||
| 33 | RPL37 | 1453729_a_at | 14693 | -0.081 | -0.4028 | No | ||
| 34 | RPS4X | 1416276_a_at | 14898 | -0.086 | -0.4087 | No | ||
| 35 | RPLP2 | 1415879_a_at | 14932 | -0.087 | -0.4066 | No | ||
| 36 | RPS17 | 1437510_x_at 1438501_at 1438986_x_at 1455662_x_at 1457940_at 1459986_a_at | 15183 | -0.094 | -0.4142 | No | ||
| 37 | RPS15A | 1453467_s_at 1457726_at | 15280 | -0.097 | -0.4147 | No | ||
| 38 | RPL19 | 1416219_at | 15333 | -0.098 | -0.4131 | No | ||
| 39 | RPL14 | 1422128_at 1426793_a_at 1433688_x_at 1436688_x_at 1438507_x_at 1438626_x_at | 16718 | -0.145 | -0.4704 | No | ||
| 40 | RPS15 | 1416088_a_at 1416089_at | 16772 | -0.147 | -0.4668 | No | ||
| 41 | RPL35A | 1417317_s_at | 17469 | -0.179 | -0.4913 | No | ||
| 42 | EIF4B | 1426378_at 1426379_at 1426380_at | 18572 | -0.262 | -0.5310 | No | ||
| 43 | RPL17 | 1423855_x_at 1435791_x_at 1453752_at | 18977 | -0.302 | -0.5371 | No | ||
| 44 | EIF4E | 1450909_at 1457489_at 1459371_at | 19374 | -0.356 | -0.5408 | No | ||
| 45 | RPL5 | 1423665_a_at 1447460_at | 21409 | -1.360 | -0.5783 | Yes | ||
| 46 | PABPC1 | 1418883_a_at 1419500_at 1453840_at | 21934 | -6.759 | -0.3270 | Yes | ||
| 47 | RPS16 | 1416404_s_at 1437196_x_at 1455835_at | 21936 | -8.031 | 0.0000 | Yes |
